Compile Data Set for Download or QSAR

Found 704 hits of ic50 for UniProtKB: P20272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50350429 (CHEMBL1814154) Show SMILES CCc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC(C)(C)c1nnnn1C Show InChI InChI=1S/C23H22BrCl2N7O/c1-5-16-19(21(34)27-23(2,3)22-28-30-31-32(22)4)29-33(18-11-10-15(25)12-17(18)26)20(16)13-6-8-14(24)9-7-13/h6-12H,5H2,1-4H3,(H,27,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	7.4	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from rat brain CB1 receptor at pH 7.4 after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 4913-8 (2011) Article DOI: 10.1016/j.bmcl.2011.06.017 BindingDB Entry DOI: 10.7270/Q2SJ1KZ7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50350458 (CHEMBL1814333) Show SMILES OCc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1(CC1)c1noc(n1)C(F)(F)F Show InChI InChI=1S/C23H15Cl3F3N5O3/c24-12-3-1-11(2-4-12)18-14(10-35)17(32-34(18)16-6-5-13(25)9-15(16)26)19(36)31-22(7-8-22)20-30-21(37-33-20)23(27,28)29/h1-6,9,35H,7-8,10H2,(H,31,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	7.4	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from rat brain CB1 receptor at pH 7.4 after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 4913-8 (2011) Article DOI: 10.1016/j.bmcl.2011.06.017 BindingDB Entry DOI: 10.7270/Q2SJ1KZ7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50350447 (CHEMBL1814329) Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1(CC1)c1noc(n1)C(F)(F)F Show InChI InChI=1S/C23H15Cl3F3N5O2/c1-11-17(19(35)31-22(8-9-22)20-30-21(36-33-20)23(27,28)29)32-34(16-7-6-14(25)10-15(16)26)18(11)12-2-4-13(24)5-3-12/h2-7,10H,8-9H2,1H3,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	7.4	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from rat brain CB1 receptor at pH 7.4 after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 4913-8 (2011) Article DOI: 10.1016/j.bmcl.2011.06.017 BindingDB Entry DOI: 10.7270/Q2SJ1KZ7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50267545 ((4-(3-cyclopropyl-5-(trifluoromethyl)phenylsulfony...) Show SMILES FC(F)(F)c1ccc(cc1)[C@@H]1C[C@H]1C(=O)N1CCN(CC1)S(=O)(=O)c1cc(cc(c1)C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C25H24F6N2O3S/c26-24(27,28)18-5-3-16(4-6-18)21-14-22(21)23(34)32-7-9-33(10-8-32)37(35,36)20-12-17(15-1-2-15)11-19(13-20)25(29,30)31/h3-6,11-13,15,21-22H,1-2,7-10,14H2/t21-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H] SR141716 from rat recombinant CB1R expressed in CHO cells				J Med Chem 52: 2550-8 (2009) Article DOI: 10.1021/jm900063x BindingDB Entry DOI: 10.7270/Q2028RF8
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50323009 (1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-me...) Show SMILES Cn1c(cc(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)N1CCC(CC1)(N1CCCCC1)C(N)=O Show InChI InChI=1S/C29H31Cl3N4O2/c1-34-25(27(37)35-15-11-29(12-16-35,28(33)38)36-13-3-2-4-14-36)18-23(22-10-9-21(31)17-24(22)32)26(34)19-5-7-20(30)8-6-19/h5-10,17-18H,2-4,11-16H2,1H3,(H2,33,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D Curated by ChEMBL					Assay Description Binding affinity to CB1 receptor in rat brain synaptosomal membranes				Bioorg Med Chem Lett 20: 4573-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.017 BindingDB Entry DOI: 10.7270/Q28G8KV6
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50200841 (CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...) Show SMILES C[C@H](NC(=O)C(C)(C)Oc1ccc(cn1)C(F)(F)F)[C@@H](Cc1ccc(Cl)cc1)c1cccc(c1)C#N |r| Show InChI InChI=1S/C27H25ClF3N3O2/c1-17(34-25(35)26(2,3)36-24-12-9-21(16-33-24)27(29,30)31)23(14-18-7-10-22(28)11-8-18)20-6-4-5-19(13-20)15-32/h4-13,16-17,23H,14H2,1-3H3,(H,34,35)/t17-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from rat brain CB1 receptor at pH 7.4 after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 4913-8 (2011) Article DOI: 10.1016/j.bmcl.2011.06.017 BindingDB Entry DOI: 10.7270/Q2SJ1KZ7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50350449 (CHEMBL1814331) Show SMILES CC(C)(NC(=O)c1nn(c(c1CO)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)c1noc(n1)C(F)(F)F Show InChI InChI=1S/C23H17Cl3F3N5O3/c1-22(2,20-30-21(37-33-20)23(27,28)29)31-19(36)17-14(10-35)18(11-3-5-12(24)6-4-11)34(32-17)16-8-7-13(25)9-15(16)26/h3-9,35H,10H2,1-2H3,(H,31,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.4	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from rat brain CB1 receptor at pH 7.4 after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 4913-8 (2011) Article DOI: 10.1016/j.bmcl.2011.06.017 BindingDB Entry DOI: 10.7270/Q2SJ1KZ7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50323003 (1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(2...) Show SMILES CS(=O)(=O)CCn1c(cc(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)N1CCC(CC1)(N1CCCCC1)C(N)=O Show InChI InChI=1S/C31H35Cl3N4O4S/c1-43(41,42)18-17-38-27(29(39)36-15-11-31(12-16-36,30(35)40)37-13-3-2-4-14-37)20-25(24-10-9-23(33)19-26(24)34)28(38)21-5-7-22(32)8-6-21/h5-10,19-20H,2-4,11-18H2,1H3,(H2,35,40)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D Curated by ChEMBL					Assay Description Binding affinity to CB1 receptor in rat brain synaptosomal membranes				Bioorg Med Chem Lett 20: 4573-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.017 BindingDB Entry DOI: 10.7270/Q28G8KV6
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50350428 (CHEMBL1814153) Show SMILES CCc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC(C)(C)c1nnnn1C Show InChI InChI=1S/C23H22Cl3N7O/c1-5-16-19(21(34)27-23(2,3)22-28-30-31-32(22)4)29-33(18-11-10-15(25)12-17(18)26)20(16)13-6-8-14(24)9-7-13/h6-12H,5H2,1-4H3,(H,27,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.4	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from rat brain CB1 receptor at pH 7.4 after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 4913-8 (2011) Article DOI: 10.1016/j.bmcl.2011.06.017 BindingDB Entry DOI: 10.7270/Q2SJ1KZ7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50275414 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...) Show SMILES Clc1ccc(cc1)C1(CC1)c1nnc(o1)-c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C29H19BrCl3N7O/c30-19-5-1-17(2-6-19)26-22(14-39-16-34-15-35-39)25(38-40(26)24-10-9-21(32)13-23(24)33)27-36-37-28(41-27)29(11-12-29)18-3-7-20(31)8-4-18/h1-10,13,15-16H,11-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometry				J Med Chem 51: 7216-33 (2009) Article DOI: 10.1021/jm800843r BindingDB Entry DOI: 10.7270/Q2PK0G0G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50325211 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...) Show SMILES CC(C)(C)c1nnc(s1)-c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl Show InChI InChI=1S/C24H21BrClN7S/c1-24(2,3)23-30-29-22(34-23)20-17(12-32-14-27-13-28-32)21(15-8-10-16(25)11-9-15)33(31-20)19-7-5-4-6-18(19)26/h4-11,13-14H,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.681	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 6377-88 (2010) Article DOI: 10.1016/j.bmc.2010.07.013 BindingDB Entry DOI: 10.7270/Q2XG9RBT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50316513 (CHEMBL1096182 | N-((4R)-6-(4-chlorophenyl)-7-(2,4-...) Show SMILES Cc1cc([nH]n1)C(=O)N[C@@H]1CC(C)(C)Oc2nc(-c3ccc(Cl)cc3Cl)c(cc12)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C27H23Cl3N4O2/c1-14-10-22(34-33-14)25(35)31-23-13-27(2,3)36-26-20(23)12-19(15-4-6-16(28)7-5-15)24(32-26)18-9-8-17(29)11-21(18)30/h4-12,23H,13H2,1-3H3,(H,31,35)(H,33,34)/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rat cannabinoid CB1 receptor				J Med Chem 53: 4028-37 (2010) Article DOI: 10.1021/jm100023j BindingDB Entry DOI: 10.7270/Q2TQ61QD
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50323007 (1-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-met...) Show SMILES Cn1c(cc(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)N1CCC(CC1)(C(N)=O)c1ccccc1 Show InChI InChI=1S/C30H26Cl3N3O2/c1-35-26(28(37)36-15-13-30(14-16-36,29(34)38)20-5-3-2-4-6-20)18-24(23-12-11-22(32)17-25(23)33)27(35)19-7-9-21(31)10-8-19/h2-12,17-18H,13-16H2,1H3,(H2,34,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D Curated by ChEMBL					Assay Description Binding affinity to CB1 receptor in rat brain synaptosomal membranes				Bioorg Med Chem Lett 20: 4573-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.017 BindingDB Entry DOI: 10.7270/Q28G8KV6
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50350448 (CHEMBL1814330) Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1(CCC1)c1noc(n1)C(F)(F)F Show InChI InChI=1S/C24H17Cl3F3N5O2/c1-12-18(20(36)32-23(9-2-10-23)21-31-22(37-34-21)24(28,29)30)33-35(17-8-7-15(26)11-16(17)27)19(12)13-3-5-14(25)6-4-13/h3-8,11H,2,9-10H2,1H3,(H,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.4	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from rat brain CB1 receptor at pH 7.4 after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 4913-8 (2011) Article DOI: 10.1016/j.bmcl.2011.06.017 BindingDB Entry DOI: 10.7270/Q2SJ1KZ7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50325221 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...) Show SMILES FC(F)(F)C1(CCC1)c1nnc(s1)-c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl Show InChI InChI=1S/C25H18BrClF3N7S/c26-16-8-6-15(7-9-16)21-17(12-36-14-31-13-32-36)20(35-37(21)19-5-2-1-4-18(19)27)22-33-34-23(38-22)24(10-3-11-24)25(28,29)30/h1-2,4-9,13-14H,3,10-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.848	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 6377-88 (2010) Article DOI: 10.1016/j.bmc.2010.07.013 BindingDB Entry DOI: 10.7270/Q2XG9RBT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50200841 (CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...) Show SMILES C[C@H](NC(=O)C(C)(C)Oc1ccc(cn1)C(F)(F)F)[C@@H](Cc1ccc(Cl)cc1)c1cccc(c1)C#N |r| Show InChI InChI=1S/C27H25ClF3N3O2/c1-17(34-25(35)26(2,3)36-24-12-9-21(16-33-24)27(29,30)31)23(14-18-7-10-22(28)11-8-18)20-6-4-5-19(13-20)15-32/h4-13,16-17,23H,14H2,1-3H3,(H,34,35)/t17-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	0.860	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometry				J Med Chem 51: 7216-33 (2009) Article DOI: 10.1021/jm800843r BindingDB Entry DOI: 10.7270/Q2PK0G0G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50325226 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...) Show SMILES Clc1ccc(cc1)C1(CC1)c1nnc(s1)-c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C29H19BrCl3N7S/c30-19-5-1-17(2-6-19)26-22(14-39-16-34-15-35-39)25(38-40(26)24-10-9-21(32)13-23(24)33)27-36-37-28(41-27)29(11-12-29)18-3-7-20(31)8-4-18/h1-10,13,15-16H,11-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.877	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 6377-88 (2010) Article DOI: 10.1016/j.bmc.2010.07.013 BindingDB Entry DOI: 10.7270/Q2XG9RBT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50275368 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...) Show SMILES FC(F)(F)C1(CC1)c1nnc(o1)-c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H15BrCl2F3N7O/c25-14-3-1-13(2-4-14)20-16(10-36-12-31-11-32-36)19(35-37(20)18-6-5-15(26)9-17(18)27)21-33-34-22(38-21)23(7-8-23)24(28,29)30/h1-6,9,11-12H,7-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.930	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometry				J Med Chem 51: 7216-33 (2009) Article DOI: 10.1021/jm800843r BindingDB Entry DOI: 10.7270/Q2PK0G0G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50275412 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...) Show SMILES Clc1ccc(c(Cl)c1)-n1nc(c(Cn2cncn2)c1-c1ccc(Br)cc1)-c1nnc(o1)C1(CC1)c1ccccc1 Show InChI InChI=1S/C29H20BrCl2N7O/c30-20-8-6-18(7-9-20)26-22(15-38-17-33-16-34-38)25(37-39(26)24-11-10-21(31)14-23(24)32)27-35-36-28(40-27)29(12-13-29)19-4-2-1-3-5-19/h1-11,14,16-17H,12-13,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.960	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometry				J Med Chem 51: 7216-33 (2009) Article DOI: 10.1021/jm800843r BindingDB Entry DOI: 10.7270/Q2PK0G0G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50325223 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chloroph...) Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccccc1Cl)-c1nnc(s1)C1(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C29H20Cl3N7S/c30-20-9-5-18(6-10-20)26-22(15-38-17-33-16-34-38)25(37-39(26)24-4-2-1-3-23(24)32)27-35-36-28(40-27)29(13-14-29)19-7-11-21(31)12-8-19/h1-12,16-17H,13-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.966	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 6377-88 (2010) Article DOI: 10.1016/j.bmc.2010.07.013 BindingDB Entry DOI: 10.7270/Q2XG9RBT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50325227 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...) Show SMILES FC(F)(F)C1(CC1)c1nnc(s1)-c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H15BrCl2F3N7S/c25-14-3-1-13(2-4-14)20-16(10-36-12-31-11-32-36)19(35-37(20)18-6-5-15(26)9-17(18)27)21-33-34-22(38-21)23(7-8-23)24(28,29)30/h1-6,9,11-12H,7-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.991	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 6377-88 (2010) Article DOI: 10.1016/j.bmc.2010.07.013 BindingDB Entry DOI: 10.7270/Q2XG9RBT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50325222 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...) Show SMILES FC(F)(F)C1(CC1)c1nnc(s1)-c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl Show InChI InChI=1S/C24H16BrClF3N7S/c25-15-7-5-14(6-8-15)20-16(11-35-13-30-12-31-35)19(34-36(20)18-4-2-1-3-17(18)26)21-32-33-22(37-21)23(9-10-23)24(27,28)29/h1-8,12-13H,9-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.992	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 6377-88 (2010) Article DOI: 10.1016/j.bmc.2010.07.013 BindingDB Entry DOI: 10.7270/Q2XG9RBT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50350450 (CHEMBL1814335) Show SMILES CCOC(=O)c1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1(CC1)c1noc(n1)C(F)(F)F Show InChI InChI=1S/C25H17Cl3F3N5O4/c1-2-39-21(38)17-18(20(37)33-24(9-10-24)22-32-23(40-35-22)25(29,30)31)34-36(16-8-7-14(27)11-15(16)28)19(17)12-3-5-13(26)6-4-12/h3-8,11H,2,9-10H2,1H3,(H,33,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from rat brain CB1 receptor at pH 7.4 after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 4913-8 (2011) Article DOI: 10.1016/j.bmcl.2011.06.017 BindingDB Entry DOI: 10.7270/Q2SJ1KZ7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50323006 (1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(3...) Show SMILES CS(=O)(=O)NCCCn1c(cc(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)N1CCC(CC1)(N1CCC(F)(F)CC1)C(N)=O Show InChI InChI=1S/C32H36Cl3F2N5O4S/c1-47(45,46)39-13-2-14-42-27(20-25(24-8-7-23(34)19-26(24)35)28(42)21-3-5-22(33)6-4-21)29(43)40-15-9-31(10-16-40,30(38)44)41-17-11-32(36,37)12-18-41/h3-8,19-20,39H,2,9-18H2,1H3,(H2,38,44)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D Curated by ChEMBL					Assay Description Binding affinity to CB1 receptor in rat brain synaptosomal membranes				Bioorg Med Chem Lett 20: 4573-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.017 BindingDB Entry DOI: 10.7270/Q28G8KV6
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50325228 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chloroph...) Show SMILES FC(F)(F)C1(CCC1)c1nnc(s1)-c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccccc1Cl Show InChI InChI=1S/C25H18Cl2F3N7S/c26-16-8-6-15(7-9-16)21-17(12-36-14-31-13-32-36)20(35-37(21)19-5-2-1-4-18(19)27)22-33-34-23(38-22)24(10-3-11-24)25(28,29)30/h1-2,4-9,13-14H,3,10-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 6377-88 (2010) Article DOI: 10.1016/j.bmc.2010.07.013 BindingDB Entry DOI: 10.7270/Q2XG9RBT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50275482 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloroph...) Show SMILES Cc1ccc(cc1)C1(CC1)c1nnc(o1)-c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C30H22Cl3N7O/c1-18-2-6-20(7-3-18)30(12-13-30)29-37-36-28(41-29)26-23(15-39-17-34-16-35-39)27(19-4-8-21(31)9-5-19)40(38-26)25-11-10-22(32)14-24(25)33/h2-11,14,16-17H,12-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometry				J Med Chem 51: 7216-33 (2009) Article DOI: 10.1021/jm800843r BindingDB Entry DOI: 10.7270/Q2PK0G0G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50310000 (4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...) Show SMILES Cc1cc(Br)ccc1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl Show InChI InChI=1S/C27H21Br2ClN6O/c1-17-12-21(29)11-8-19(17)13-32-27(37)25-22(14-35-16-31-15-33-35)26(18-6-9-20(28)10-7-18)36(34-25)24-5-3-2-4-23(24)30/h2-12,15-16H,13-14H2,1H3,(H,32,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane				Bioorg Med Chem 18: 1149-62 (2010) Article DOI: 10.1016/j.bmc.2009.12.040 BindingDB Entry DOI: 10.7270/Q2TD9XG2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50350430 (CHEMBL1814155) Show SMILES CCCS(=O)(=O)Oc1ccc(cc1)-c1c(C)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NC(C)(C)c1nnnn1C Show InChI InChI=1S/C25H27Cl2N7O4S/c1-6-13-39(36,37)38-18-10-7-16(8-11-18)22-15(2)21(30-34(22)20-12-9-17(26)14-19(20)27)23(35)28-25(3,4)24-29-31-32-33(24)5/h7-12,14H,6,13H2,1-5H3,(H,28,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.4	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from rat brain CB1 receptor at pH 7.4 after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 4913-8 (2011) Article DOI: 10.1016/j.bmcl.2011.06.017 BindingDB Entry DOI: 10.7270/Q2SJ1KZ7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50275413 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...) Show SMILES Cc1ccc(cc1)C1(CC1)c1nnc(o1)-c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C30H22BrCl2N7O/c1-18-2-6-20(7-3-18)30(12-13-30)29-37-36-28(41-29)26-23(15-39-17-34-16-35-39)27(19-4-8-21(31)9-5-19)40(38-26)25-11-10-22(32)14-24(25)33/h2-11,14,16-17H,12-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometry				J Med Chem 51: 7216-33 (2009) Article DOI: 10.1021/jm800843r BindingDB Entry DOI: 10.7270/Q2PK0G0G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50278254 (5-(4-bromophenyl)-3-(5-tert-butyl-1,3,4-oxadiazol-...) Show SMILES CC(C)(C)c1nnc(o1)-c1nn(c(c1C(=O)Nc1ccccc1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C28H22BrCl2N5O2/c1-28(2,3)27-34-33-26(38-27)23-22(25(37)32-19-7-5-4-6-8-19)24(16-9-11-17(29)12-10-16)36(35-23)21-14-13-18(30)15-20(21)31/h4-15H,1-3H3,(H,32,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 from cannabinoid CB1 receptor in Sprague-Dawley rat cerebellar membrane by liquid scintillation spectrometry				Bioorg Med Chem Lett 19: 1899-902 (2009) Article DOI: 10.1016/j.bmcl.2009.02.063 BindingDB Entry DOI: 10.7270/Q26T0MHX
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50032599 ((4-Methoxy-naphthalen-1-yl)-[1-(2-morpholin-4-yl-e...) Show SMILES COc1ccc(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C26H26N2O3/c1-30-25-11-10-22(19-6-2-3-8-21(19)25)26(29)23-18-28(24-9-5-4-7-20(23)24)13-12-27-14-16-31-17-15-27/h2-11,18H,12-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research Division Curated by ChEMBL					Assay Description Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.				J Med Chem 38: 3094-105 (1995) BindingDB Entry DOI: 10.7270/Q2DN442Z
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50323004 (1'-(5-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-1-(3...) Show SMILES CS(=O)(=O)NCCCn1c(cc(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)N1CCC(CC1)(N1CCCCC1)C(N)=O Show InChI InChI=1S/C32H38Cl3N5O4S/c1-45(43,44)37-14-5-17-40-28(30(41)38-18-12-32(13-19-38,31(36)42)39-15-3-2-4-16-39)21-26(25-11-10-24(34)20-27(25)35)29(40)22-6-8-23(33)9-7-22/h6-11,20-21,37H,2-5,12-19H2,1H3,(H2,36,42)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D Curated by ChEMBL					Assay Description Binding affinity to CB1 receptor in rat brain synaptosomal membranes				Bioorg Med Chem Lett 20: 4573-7 (2010) Article DOI: 10.1016/j.bmcl.2010.06.017 BindingDB Entry DOI: 10.7270/Q28G8KV6
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50309995 (4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...) Show SMILES Cc1cc(Br)ccc1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C27H20Br2Cl2N6O/c1-16-10-20(29)7-4-18(16)12-33-27(38)25-22(13-36-15-32-14-34-36)26(17-2-5-19(28)6-3-17)37(35-25)24-9-8-21(30)11-23(24)31/h2-11,14-15H,12-13H2,1H3,(H,33,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane				Bioorg Med Chem 18: 1149-62 (2010) Article DOI: 10.1016/j.bmc.2009.12.040 BindingDB Entry DOI: 10.7270/Q2TD9XG2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50278255 (5-(4-bromophenyl)-3-(5-tert-butyl-1,3,4-oxadiazol-...) Show SMILES CC(C)(C)c1nnc(o1)-c1nn(c(c1C(=O)Nc1ccccn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C27H21BrCl2N6O2/c1-27(2,3)26-34-33-25(38-26)22-21(24(37)32-20-6-4-5-13-31-20)23(15-7-9-16(28)10-8-15)36(35-22)19-12-11-17(29)14-18(19)30/h4-14H,1-3H3,(H,31,32,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 from cannabinoid CB1 receptor in Sprague-Dawley rat cerebellar membrane by liquid scintillation spectrometry				Bioorg Med Chem Lett 19: 1899-902 (2009) Article DOI: 10.1016/j.bmcl.2009.02.063 BindingDB Entry DOI: 10.7270/Q26T0MHX
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50278201 (3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-(4-chlorop...) Show SMILES CC(C)(C)c1nnc(o1)-c1nn(c(c1C(=O)Nc1ccccn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C27H21Cl3N6O2/c1-27(2,3)26-34-33-25(38-26)22-21(24(37)32-20-6-4-5-13-31-20)23(15-7-9-16(28)10-8-15)36(35-22)19-12-11-17(29)14-18(19)30/h4-14H,1-3H3,(H,31,32,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.47	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 from cannabinoid CB1 receptor in Sprague-Dawley rat cerebellar membrane by liquid scintillation spectrometry				Bioorg Med Chem Lett 19: 1899-902 (2009) Article DOI: 10.1016/j.bmcl.2009.02.063 BindingDB Entry DOI: 10.7270/Q26T0MHX
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50275480 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloroph...) Show SMILES FC(F)(F)C1(CC1)c1nnc(o1)-c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H15Cl3F3N7O/c25-14-3-1-13(2-4-14)20-16(10-36-12-31-11-32-36)19(35-37(20)18-6-5-15(26)9-17(18)27)21-33-34-22(38-21)23(7-8-23)24(28,29)30/h1-6,9,11-12H,7-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.51	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellum by liquid scintillation spectrometry				J Med Chem 51: 7216-33 (2009) Article DOI: 10.1021/jm800843r BindingDB Entry DOI: 10.7270/Q2PK0G0G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50325213 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...) Show SMILES CC(C)(C)c1nnc(s1)-c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H20BrCl2N7S/c1-24(2,3)23-31-30-22(35-23)20-17(11-33-13-28-12-29-33)21(14-4-6-15(25)7-5-14)34(32-20)19-9-8-16(26)10-18(19)27/h4-10,12-13H,11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.54	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 6377-88 (2010) Article DOI: 10.1016/j.bmc.2010.07.013 BindingDB Entry DOI: 10.7270/Q2XG9RBT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50310005 (4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...) Show SMILES Clc1ccccc1-n1nc(C(=O)NC2CCCCC2)c(Cn2cncn2)c1-c1ccc(Br)cc1 Show InChI InChI=1S/C25H24BrClN6O/c26-18-12-10-17(11-13-18)24-20(14-32-16-28-15-29-32)23(25(34)30-19-6-2-1-3-7-19)31-33(24)22-9-5-4-8-21(22)27/h4-5,8-13,15-16,19H,1-3,6-7,14H2,(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane				Bioorg Med Chem 18: 1149-62 (2010) Article DOI: 10.1016/j.bmc.2009.12.040 BindingDB Entry DOI: 10.7270/Q2TD9XG2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50278136 (3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-(4-chlorop...) Show SMILES CC(C)(C)c1nnc(o1)-c1nn(c(c1C(=O)Nc1ccccc1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C28H22Cl3N5O2/c1-28(2,3)27-34-33-26(38-27)23-22(25(37)32-19-7-5-4-6-8-19)24(16-9-11-17(29)12-10-16)36(35-23)21-14-13-18(30)15-20(21)31/h4-15H,1-3H3,(H,32,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 from cannabinoid CB1 receptor in Sprague-Dawley rat cerebellar membrane by liquid scintillation spectrometry				Bioorg Med Chem Lett 19: 1899-902 (2009) Article DOI: 10.1016/j.bmcl.2009.02.063 BindingDB Entry DOI: 10.7270/Q26T0MHX
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50325229 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chloroph...) Show SMILES FC(F)(F)C1(CC1)c1nnc(s1)-c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccccc1Cl Show InChI InChI=1S/C24H16Cl2F3N7S/c25-15-7-5-14(6-8-15)20-16(11-35-13-30-12-31-35)19(34-36(20)18-4-2-1-3-17(18)26)21-32-33-22(37-21)23(9-10-23)24(27,28)29/h1-8,12-13H,9-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 6377-88 (2010) Article DOI: 10.1016/j.bmc.2010.07.013 BindingDB Entry DOI: 10.7270/Q2XG9RBT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50310003 (4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...) Show SMILES Clc1ccc(cc1)C1(CC1)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl Show InChI InChI=1S/C28H21BrCl2N6O/c29-20-9-5-18(6-10-20)26-22(15-36-17-32-16-33-36)25(35-37(26)24-4-2-1-3-23(24)31)27(38)34-28(13-14-28)19-7-11-21(30)12-8-19/h1-12,16-17H,13-15H2,(H,34,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane				Bioorg Med Chem 18: 1149-62 (2010) Article DOI: 10.1016/j.bmc.2009.12.040 BindingDB Entry DOI: 10.7270/Q2TD9XG2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50303019 (2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-m...) Show SMILES Cc1nnc(s1)-c1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)-c1nnc(o1)C1(CC1)C(F)(F)F Show InChI InChI=1S/C24H14BrCl2F3N6OS/c1-11-31-33-21(38-11)17-18(20-32-34-22(37-20)23(8-9-23)24(28,29)30)35-36(16-7-6-14(26)10-15(16)27)19(17)12-2-4-13(25)5-3-12/h2-7,10H,8-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane				Bioorg Med Chem Lett 19: 6632-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.015 BindingDB Entry DOI: 10.7270/Q2NC6191
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50325224 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloroph...) Show SMILES CC(C)(C)c1nnc(s1)-c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H20Cl3N7S/c1-24(2,3)23-31-30-22(35-23)20-17(11-33-13-28-12-29-33)21(14-4-6-15(25)7-5-14)34(32-20)19-9-8-16(26)10-18(19)27/h4-10,12-13H,11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.73	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 6377-88 (2010) Article DOI: 10.1016/j.bmc.2010.07.013 BindingDB Entry DOI: 10.7270/Q2XG9RBT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50325230 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloroph...) Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)-c1nnc(s1)C1(CC1)c1ccccc1 Show InChI InChI=1S/C29H20Cl3N7S/c30-20-8-6-18(7-9-20)26-22(15-38-17-33-16-34-38)25(37-39(26)24-11-10-21(31)14-23(24)32)27-35-36-28(40-27)29(12-13-29)19-4-2-1-3-5-19/h1-11,14,16-17H,12-13,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.79	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 6377-88 (2010) Article DOI: 10.1016/j.bmc.2010.07.013 BindingDB Entry DOI: 10.7270/Q2XG9RBT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50309988 (4-((1H-1,2,4-Triazol-1-yl)methyl)-N-(1-(4-bromophe...) Show SMILES Cc1cc(Br)ccc1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccccc1Cl Show InChI InChI=1S/C27H21BrCl2N6O/c1-17-12-20(28)9-6-19(17)13-32-27(37)25-22(14-35-16-31-15-33-35)26(18-7-10-21(29)11-8-18)36(34-25)24-5-3-2-4-23(24)30/h2-12,15-16H,13-14H2,1H3,(H,32,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane				Bioorg Med Chem 18: 1149-62 (2010) Article DOI: 10.1016/j.bmc.2009.12.040 BindingDB Entry DOI: 10.7270/Q2TD9XG2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50267487 (1-(4-(3-cyclopropyl-5-(trifluoromethyl)phenylsulfo...) Show SMILES FC(F)(F)c1ccc(CC(=O)N2CCN(CC2)S(=O)(=O)c2cc(cc(c2)C(F)(F)F)C2CC2)cc1 Show InChI InChI=1S/C23H22F6N2O3S/c24-22(25,26)18-5-1-15(2-6-18)11-21(32)30-7-9-31(10-8-30)35(33,34)20-13-17(16-3-4-16)12-19(14-20)23(27,28)29/h1-2,5-6,12-14,16H,3-4,7-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant CB1R expressed in CHO cells assessed as inhibition of methanandamide-stimulated cAMP level				J Med Chem 52: 2550-8 (2009) Article DOI: 10.1021/jm900063x BindingDB Entry DOI: 10.7270/Q2028RF8
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Central Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebella membrane				Bioorg Med Chem 16: 4035-51 (2008) Article DOI: 10.1016/j.bmc.2008.01.023 BindingDB Entry DOI: 10.7270/Q2B56JH2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50254919 (2-(1-(4-bromophenyl)-2-(2,4-dichlorophenyl)-5-ethy...) Show SMILES CCc1c(nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Br)cc1)-c1nnc(s1)C(C)(C)C Show InChI InChI=1S/C23H21BrCl2N4S/c1-5-18-19(21-28-29-22(31-21)23(2,3)4)27-20(16-11-8-14(25)12-17(16)26)30(18)15-9-6-13(24)7-10-15/h6-12H,5H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.91	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane				Bioorg Med Chem Lett 19: 142-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.130 BindingDB Entry DOI: 10.7270/Q2T153H8
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50325231 (2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chloroph...) Show SMILES CC(C)(C)c1nnc(s1)-c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccccc1Cl Show InChI InChI=1S/C24H21Cl2N7S/c1-24(2,3)23-30-29-22(34-23)20-17(12-32-14-27-13-28-32)21(15-8-10-16(25)11-9-15)33(31-20)19-7-5-4-6-18(19)26/h4-11,13-14H,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.93	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 6377-88 (2010) Article DOI: 10.1016/j.bmc.2010.07.013 BindingDB Entry DOI: 10.7270/Q2XG9RBT
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50278311 (5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-N-phenyl-...) Show SMILES FC(F)(F)C1(CC1)c1nnc(o1)-c1nn(c(c1C(=O)Nc1ccccc1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C28H17BrCl2F3N5O2/c29-16-8-6-15(7-9-16)23-21(24(40)35-18-4-2-1-3-5-18)22(38-39(23)20-11-10-17(30)14-19(20)31)25-36-37-26(41-25)27(12-13-27)28(32,33)34/h1-11,14H,12-13H2,(H,35,40)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.94	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 from cannabinoid CB1 receptor in Sprague-Dawley rat cerebellar membrane by liquid scintillation spectrometry				Bioorg Med Chem Lett 19: 1899-902 (2009) Article DOI: 10.1016/j.bmcl.2009.02.063 BindingDB Entry DOI: 10.7270/Q26T0MHX
					More data for this Ligand-Target Pair

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