BindingDB PrimarySearch

Found 111 hits of ec50 for UniProtKB: P61169
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50090828 ((-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9-...) Show SMILES CCCN1CCO[C@H]2[C@H]1CSc1ccc(O)cc21 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	0.0130	n/a	n/a	n/a	n/a
University Centre for Pharmacy Curated by ChEMBL					Assay Description Agonist activity by measuring the [3H]thymidine uptake against Dopamine receptor D2L from rat				J Med Chem 43: 2871-82 (2000) BindingDB Entry DOI: 10.7270/Q2X067R1
University Centre for Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D2 using FLIPR assay				J Med Chem 47: 3853-64 (2004) Article DOI: 10.1021/jm030505a BindingDB Entry DOI: 10.7270/Q24B3225
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Agonist activity at rat D2 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPR				J Med Chem 49: 7450-65 (2006) Article DOI: 10.1021/jm060662k BindingDB Entry DOI: 10.7270/Q25X28MM
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE \| 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D2 using FLIPR assay				J Med Chem 47: 3853-64 (2004) Article DOI: 10.1021/jm030505a BindingDB Entry DOI: 10.7270/Q24B3225
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE \| 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Agonist activity at rat D2 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPR				J Med Chem 49: 7450-65 (2006) Article DOI: 10.1021/jm060662k BindingDB Entry DOI: 10.7270/Q25X28MM
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assay				J Med Chem 47: 3853-64 (2004) Article DOI: 10.1021/jm030505a BindingDB Entry DOI: 10.7270/Q24B3225
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50020222 ((+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthal...) Show SMILES CCCN(CCC)C1CCc2ccc(O)cc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at Rattus norvegicus (rat) dopamine D2 receptor transfected in african green monkey COS7 cells assessed as inhibition of forskolin-s...				Citation and Details Article DOI: 10.1007/s00044-004-0006-x BindingDB Entry DOI: 10.7270/Q2377CM7
TBA					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a
University Centre for Pharmacy Curated by ChEMBL					Assay Description Agonist activity by measuring the [3H]thymidine uptake against Dopamine receptor D2L from rat				J Med Chem 43: 2871-82 (2000) BindingDB Entry DOI: 10.7270/Q2X067R1
University Centre for Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE \| 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Activity at rat dopamine D2L receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production				J Med Chem 49: 6848-57 (2006) Article DOI: 10.1021/jm0604979 BindingDB Entry DOI: 10.7270/Q25T3M92
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010586 ((+)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-diox...) Show SMILES CCCN1CCO[C@H]2[C@H]1COc1ccc(O)cc21 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	5.70	n/a	n/a	n/a	n/a
University Centre for Pharmacy Curated by ChEMBL					Assay Description Agonist activity by measuring the [3H]thymidine uptake against Dopamine receptor D2L from rat				J Med Chem 43: 2871-82 (2000) BindingDB Entry DOI: 10.7270/Q2X067R1
University Centre for Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50092173 (CHEMBL325710 \| N6,N6-Dipropyl-6,7-dihydro-5H-1...) Show SMILES CCCN(CCC)C1Cc2cc3nc(N)sc3cc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	5.70	n/a	n/a	n/a	n/a
University of Maastricht Curated by ChEMBL					Assay Description Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D2L by mitogenesis assay (intri...				J Med Chem 43: 3549-57 (2000) BindingDB Entry DOI: 10.7270/Q2B27W0T
University of Maastricht Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017543 ((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at Rattus norvegicus (rat) dopamine D2 receptor transfected in african green monkey COS7 cells assessed as inhibition of forskolin-s...				Citation and Details Article DOI: 10.1007/s00044-004-0006-x BindingDB Entry DOI: 10.7270/Q2377CM7
TBA					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE \| 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assay				J Med Chem 47: 3853-64 (2004) Article DOI: 10.1021/jm030505a BindingDB Entry DOI: 10.7270/Q24B3225
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50251027 ((R)-(-)-2-(4-Hydroxyphenyl)-apomorphine hydrochlor...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.5	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...				Bioorg Med Chem 17: 4756-62 (2009) Article DOI: 10.1016/j.bmc.2009.04.047 BindingDB Entry DOI: 10.7270/Q2KD1XZ4
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50295863 (CHEMBL562935 \| N-Ethyl-2-(4-hydroxyphenyl)-norapom...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.70	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...				Bioorg Med Chem 17: 4756-62 (2009) Article DOI: 10.1016/j.bmc.2009.04.047 BindingDB Entry DOI: 10.7270/Q2KD1XZ4
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Activity at rat dopamine D2L receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production				J Med Chem 49: 6848-57 (2006) Article DOI: 10.1021/jm0604979 BindingDB Entry DOI: 10.7270/Q25T3M92
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50116766 ((-)-Pramipexole \| (6S)-N(6)-propyl-4,5,6,7-tetrahy...) Show SMILES CCCN[C@H]1CCc2nc(N)sc2C1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	9.20	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Effective concentration required for agonistic activity against rat D2 long receptor				Bioorg Med Chem Lett 12: 2377-80 (2002) BindingDB Entry DOI: 10.7270/Q2Z89BRG
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50116766 ((-)-Pramipexole \| (6S)-N(6)-propyl-4,5,6,7-tetrahy...) Show SMILES CCCN[C@H]1CCc2nc(N)sc2C1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.20	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Effective concentration to stimulate rat Dopamine receptor D2L mediated [3H]-thymidine incorporation into growing cells using mitogenesis assay				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50056443 ((R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-...) Show SMILES CN[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10.8	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D2 using FLIPR assay				J Med Chem 47: 3853-64 (2004) Article DOI: 10.1021/jm030505a BindingDB Entry DOI: 10.7270/Q24B3225
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50105731 ((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...) Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Effective concentration to stimulate rat Dopamine receptor D2L mediated [3H]-thymidine incorporation into growing cells using mitogenesis assay				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50295866 (CHEMBL560721 \| N-Propyl-2-(4-hydroxyphenyl)-norapo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...				Bioorg Med Chem 17: 4756-62 (2009) Article DOI: 10.1016/j.bmc.2009.04.047 BindingDB Entry DOI: 10.7270/Q2KD1XZ4
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50116766 ((-)-Pramipexole \| (6S)-N(6)-propyl-4,5,6,7-tetrahy...) Show SMILES CCCN[C@H]1CCc2nc(N)sc2C1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D2 long (high/low affinity is given as 230/53000)				Bioorg Med Chem Lett 12: 2377-80 (2002) BindingDB Entry DOI: 10.7270/Q2Z89BRG
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50116766 ((-)-Pramipexole \| (6S)-N(6)-propyl-4,5,6,7-tetrahy...) Show SMILES CCCN[C@H]1CCc2nc(N)sc2C1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Effective concentration to stimulate rat Dopamine receptor D2S mediated [3H]-thymidine incorporation into growing cells using mitogenesis assay				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50347558 (CHEMBL1802233) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Agonist activity at rat D2 dopamine receptor expressed in CHOK1 cells assessed as [35S]GTPgammaS binding after 90 mins by liquid scintillation counte...				Eur J Med Chem 46: 2992-9 (2011) Article DOI: 10.1016/j.ejmech.2011.04.028 BindingDB Entry DOI: 10.7270/Q2X34XTG
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50116767 (CHEMBL310867 \| Dipropyl-(S)-1,2,3,4-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@H]1CCc2nn3ccccc3c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Effective concentration required for agonistic activity against rat Dopamine receptor D2L				Bioorg Med Chem Lett 12: 2377-80 (2002) BindingDB Entry DOI: 10.7270/Q2Z89BRG
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Effective concentration to stimulate rat Dopamine receptor D2S mediated [3H]-thymidine incorporation into growing cells using mitogenesis assay				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50092169 (CHEMBL118636 \| N7,N7-Dipropyl-7,8-dihydro-6H-1...) Show SMILES CCCN(CCC)C1Cc2ccc3nc(N)sc3c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
University of Maastricht Curated by ChEMBL					Assay Description Effective concentration was determined as thymidine uptake in CHO-L6 cells transfected with the rat Dopamine receptor D2L by mitogenesis assay (intri...				J Med Chem 43: 3549-57 (2000) BindingDB Entry DOI: 10.7270/Q2B27W0T
University of Maastricht Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010617 ((-)-3-(1-Propyl-piperidin-3-yl)-phenol \| (S)-3-(1-...) Show SMILES CCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Effective concentration required for agonistic activity against rat D2 long receptor				Bioorg Med Chem Lett 12: 2377-80 (2002) BindingDB Entry DOI: 10.7270/Q2Z89BRG
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010617 ((-)-3-(1-Propyl-piperidin-3-yl)-phenol \| (S)-3-(1-...) Show SMILES CCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Effective concentration required for agonistic activity against rat D2 long receptor				Bioorg Med Chem Lett 12: 2377-80 (2002) BindingDB Entry DOI: 10.7270/Q2Z89BRG
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50116766 ((-)-Pramipexole \| (6S)-N(6)-propyl-4,5,6,7-tetrahy...) Show SMILES CCCN[C@H]1CCc2nc(N)sc2C1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at Rattus norvegicus (rat) dopamine D2 receptor transfected in african green monkey COS7 cells assessed as inhibition of forskolin-s...				Citation and Details Article DOI: 10.1007/s00044-004-0006-x BindingDB Entry DOI: 10.7270/Q2377CM7
TBA					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50251026 ((R)-(-)-2-Phenyl-apomorphine hydrochloride \| CHEMB...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...				Bioorg Med Chem 17: 4756-62 (2009) Article DOI: 10.1016/j.bmc.2009.04.047 BindingDB Entry DOI: 10.7270/Q2KD1XZ4
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50347560 (CHEMBL1802235) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Agonist activity at rat D2 dopamine receptor expressed in CHOK1 cells assessed as [35S]GTPgammaS binding after 90 mins by liquid scintillation counte...				Eur J Med Chem 46: 2992-9 (2011) Article DOI: 10.1016/j.ejmech.2011.04.028 BindingDB Entry DOI: 10.7270/Q2X34XTG
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Agonist activity at rat D2 dopamine receptor expressed in CHOK1 cells assessed as [35S]GTPgammaS binding after 90 mins by liquid scintillation counte...				Eur J Med Chem 46: 2992-9 (2011) Article DOI: 10.1016/j.ejmech.2011.04.028 BindingDB Entry DOI: 10.7270/Q2X34XTG
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50056443 ((R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-...) Show SMILES CN[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assay				J Med Chem 47: 3853-64 (2004) Article DOI: 10.1021/jm030505a BindingDB Entry DOI: 10.7270/Q24B3225
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50295864 (CHEMBL550180 \| N-Propyl-2-methylnorapomorphine hyd...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...				Bioorg Med Chem 17: 4756-62 (2009) Article DOI: 10.1016/j.bmc.2009.04.047 BindingDB Entry DOI: 10.7270/Q2KD1XZ4
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50164427 ((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...) Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C#N Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Effective concentration to stimulate rat Dopamine receptor D2L mediated [3H]-thymidine incorporation into growing cells using mitogenesis assay				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50251028 ((R)-(-)-2-Methyl-apomorphine hydrochloride \| CHEMB...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...				Bioorg Med Chem 17: 4756-62 (2009) Article DOI: 10.1016/j.bmc.2009.04.047 BindingDB Entry DOI: 10.7270/Q2KD1XZ4
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50116767 (CHEMBL310867 \| Dipropyl-(S)-1,2,3,4-tetrahydro-pyr...) Show SMILES CCCN(CCC)[C@H]1CCc2nn3ccccc3c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Binding affinity of compound measured using [3H]-spiperone for the cloned human dopamine receptor D4.4 (high/low affinity is given as 16/1300)				Bioorg Med Chem Lett 12: 2377-80 (2002) BindingDB Entry DOI: 10.7270/Q2Z89BRG
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Effective concentration to stimulate rat Dopamine receptor D2L mediated [3H]-thymidine incorporation into growing cells using mitogenesis assay				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM86473 (S32504 (+)) Show SMILES CCCN1CCO[C@H]2[C@H]1CCc1ccc(cc21)C(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at Rattus norvegicus (rat) dopamine D2 receptor transfected in african green monkey COS7 cells assessed as inhibition of forskolin-s...				Citation and Details Article DOI: 10.1007/s00044-004-0006-x BindingDB Entry DOI: 10.7270/Q2377CM7
TBA					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50295862 (CHEMBL564909 \| N-Ethyl-2-phenylnorapomorphine hydr...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...				Bioorg Med Chem 17: 4756-62 (2009) Article DOI: 10.1016/j.bmc.2009.04.047 BindingDB Entry DOI: 10.7270/Q2KD1XZ4
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...				Bioorg Med Chem 17: 4756-62 (2009) Article DOI: 10.1016/j.bmc.2009.04.047 BindingDB Entry DOI: 10.7270/Q2KD1XZ4
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50251320 ((R)-2-Ethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-diben...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Agonist activity at rat dopamine D2(short) receptor expressed in CHOK1 cells by [35S]GTPgammaS binding assay				Bioorg Med Chem 16: 4563-8 (2008) Article DOI: 10.1016/j.bmc.2008.02.038 BindingDB Entry DOI: 10.7270/Q24J0DW0
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50145073 (5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1...) Show SMILES Fc1ccc2[nH]c(CN3CCN(CC3)c3ccccn3)cc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D2 using FLIPR assay				J Med Chem 47: 3853-64 (2004) Article DOI: 10.1021/jm030505a BindingDB Entry DOI: 10.7270/Q24B3225
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50251327 ((R)-2-Butoxy-6-methyl-5,6,6a,7-tetrahydro-4H-diben...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	58	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Agonist activity at rat dopamine D2(short) receptor expressed in CHOK1 cells by [35S]GTPgammaS binding assay				Bioorg Med Chem 16: 4563-8 (2008) Article DOI: 10.1016/j.bmc.2008.02.038 BindingDB Entry DOI: 10.7270/Q24J0DW0
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010686 ((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...) Show SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Activity at rat dopamine D2L receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production				J Med Chem 49: 6848-57 (2006) Article DOI: 10.1021/jm0604979 BindingDB Entry DOI: 10.7270/Q25T3M92
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50251321 ((R)-6-Methyl-2-propoxy-5,6,6a,7-tetrahydro-4H-dibe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Agonist activity at rat dopamine D2(short) receptor expressed in CHOK1 cells by [35S]GTPgammaS binding assay				Bioorg Med Chem 16: 4563-8 (2008) Article DOI: 10.1016/j.bmc.2008.02.038 BindingDB Entry DOI: 10.7270/Q24J0DW0
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at Rattus norvegicus (rat) dopamine D2 receptor transfected in african green monkey COS7 cells assessed as inhibition of forskolin-s...				Citation and Details Article DOI: 10.1007/s00044-004-0006-x BindingDB Entry DOI: 10.7270/Q2377CM7
TBA					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50105731 ((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...) Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	79	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Effective concentration to stimulate rat Dopamine receptor D2S mediated [3H]-thymidine incorporation into growing cells using mitogenesis assay				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50090832 ((cis)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9...) Show SMILES CCCN1CCO[C@H]2[C@@H]1CSc1ccc(O)cc21 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	122	n/a	n/a	n/a	n/a
University Centre for Pharmacy Curated by ChEMBL					Assay Description Agonist activity by measuring the [3H]thymidine uptake against Dopamine receptor D2L from rat				J Med Chem 43: 2871-82 (2000) BindingDB Entry DOI: 10.7270/Q2X067R1
University Centre for Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair

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