Compile Data Set for Download or QSAR

Found 27 hits of ec50 for UniProtKB: P53779   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10/8/9 (Homo sapiens (Human))	BDBM86636 (JNK-IN-11) Show SMILES CN(C)C\C=C\C(=O)Nc1cccc(c1)C(=O)Nc1ccc(Nc2nccc(n2)-c2c(nn3ccccc23)-c2ccccc2)cc1 Show InChI InChI=1S/C36H32N8O2/c1-43(2)22-9-15-32(45)38-29-13-8-12-26(24-29)35(46)39-27-16-18-28(19-17-27)40-36-37-21-20-30(41-36)33-31-14-6-7-23-44(31)42-34(33)25-10-4-3-5-11-25/h3-21,23-24H,22H2,1-2H3,(H,38,45)(H,39,46)(H,37,40,41)/b15-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.60	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01947 BindingDB Entry DOI: 10.7270/Q2CV4NSB
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492961 (CHEMBL2414924) Show SMILES COc1cc2[nH]c-3c(CCc4c[nH]nc-34)c2cc1C#N Show InChI InChI=1S/C15H12N4O/c1-20-13-5-12-11(4-9(13)6-16)10-3-2-8-7-17-19-14(8)15(10)18-12/h4-5,7,18H,2-3H2,1H3,(H,17,19)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492955 (CHEMBL2414923) Show SMILES COc1cc2[nH]c-3c(CCc4c[nH]nc-34)c2cc1OC Show InChI InChI=1S/C15H15N3O2/c1-19-12-5-10-9-4-3-8-7-16-18-14(8)15(9)17-11(10)6-13(12)20-2/h5-7,17H,3-4H2,1-2H3,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/8/9 (Homo sapiens (Human))	BDBM86636 (JNK-IN-11) Show SMILES CN(C)C\C=C\C(=O)Nc1cccc(c1)C(=O)Nc1ccc(Nc2nccc(n2)-c2c(nn3ccccc23)-c2ccccc2)cc1 Show InChI InChI=1S/C36H32N8O2/c1-43(2)22-9-15-32(45)38-29-13-8-12-26(24-29)35(46)39-27-16-18-28(19-17-27)40-36-37-21-20-30(41-36)33-31-14-6-7-23-44(31)42-34(33)25-10-4-3-5-11-25/h3-21,23-24H,22H2,1-2H3,(H,38,45)(H,39,46)(H,37,40,41)/b15-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01947 BindingDB Entry DOI: 10.7270/Q2CV4NSB
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492952 (CHEMBL2414918) Show SMILES N#Cc1ccc2[nH]c-3c(CCc4c[nH]nc-34)c2c1 Show InChI InChI=1S/C14H10N4/c15-6-8-1-4-12-11(5-8)10-3-2-9-7-16-18-13(9)14(10)17-12/h1,4-5,7,17H,2-3H2,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492957 (CHEMBL2414921) Show SMILES COc1ccc2c3CCc4c[nH]nc4-c3[nH]c2c1 Show InChI InChI=1S/C14H13N3O/c1-18-9-3-5-10-11-4-2-8-7-15-17-13(8)14(11)16-12(10)6-9/h3,5-7,16H,2,4H2,1H3,(H,15,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492944 (CHEMBL2414925) Show SMILES COc1cc(OC)c2c3CCc4c[nH]nc4-c3[nH]c2c1 Show InChI InChI=1S/C15H15N3O2/c1-19-9-5-11-13(12(6-9)20-2)10-4-3-8-7-16-18-14(8)15(10)17-11/h5-7,17H,3-4H2,1-2H3,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492945 (CHEMBL2414922) Show SMILES N#Cc1ccc2c3CCc4c[nH]nc4-c3[nH]c2c1 Show InChI InChI=1S/C14H10N4/c15-6-8-1-3-10-11-4-2-9-7-16-18-13(9)14(11)17-12(10)5-8/h1,3,5,7,17H,2,4H2,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492948 (CHEMBL2414915) Show SMILES Fc1ccc2[nH]c-3c(CCc4c[nH]nc-34)c2c1 Show InChI InChI=1S/C13H10FN3/c14-8-2-4-11-10(5-8)9-3-1-7-6-15-17-12(7)13(9)16-11/h2,4-6,16H,1,3H2,(H,15,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492956 (CHEMBL2414926) Show SMILES C1Oc2cc3[nH]c-4c(CCc5c[nH]nc-45)c3cc2O1 Show InChI InChI=1S/C14H11N3O2/c1-2-8-9-3-11-12(19-6-18-11)4-10(9)16-14(8)13-7(1)5-15-17-13/h3-5,16H,1-2,6H2,(H,15,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492964 (CHEMBL2414917) Show SMILES COc1ccc2[nH]c-3c(CCc4c[nH]nc-34)c2c1 Show InChI InChI=1S/C14H13N3O/c1-18-9-3-5-12-11(6-9)10-4-2-8-7-15-17-13(8)14(10)16-12/h3,5-7,16H,2,4H2,1H3,(H,15,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492946 (CHEMBL2414920) Show SMILES FC(F)(F)c1ccc2c3CCc4c[nH]nc4-c3[nH]c2c1 Show InChI InChI=1S/C14H10F3N3/c15-14(16,17)8-2-4-9-10-3-1-7-6-18-20-12(7)13(10)19-11(9)5-8/h2,4-6,19H,1,3H2,(H,18,20)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492947 (CHEMBL2414919) Show SMILES Clc1ccc2c3CCc4c[nH]nc4-c3[nH]c2c1 Show InChI InChI=1S/C13H10ClN3/c14-8-2-4-9-10-3-1-7-6-15-17-12(7)13(10)16-11(9)5-8/h2,4-6,16H,1,3H2,(H,15,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM24713 (1,2,4,5-tetrahydropyrazolo[3,4-a]carbazole | 3,4,1...) Show SMILES C1Cc2c([nH]c3ccccc23)-c2n[nH]cc12 Show InChI InChI=1S/C13H11N3/c1-2-4-11-9(3-1)10-6-5-8-7-14-16-12(8)13(10)15-11/h1-4,7,15H,5-6H2,(H,14,16)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50389604 (CHEMBL1929485) Show SMILES C1Cc2c[nH]nc2-c2[nH]c3ccccc3c2C1 Show InChI InChI=1S/C14H13N3/c1-2-7-12-10(5-1)11-6-3-4-9-8-15-17-13(9)14(11)16-12/h1-2,5,7-8,16H,3-4,6H2,(H,15,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	640	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492958 (CHEMBL2414985) Show SMILES Clc1cccc2[nH]c-3c(CCc4c[nH]nc-34)c12 Show InChI InChI=1S/C13H10ClN3/c14-9-2-1-3-10-11(9)8-5-4-7-6-15-17-12(7)13(8)16-10/h1-3,6,16H,4-5H2,(H,15,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492951 (CHEMBL2414983) Show SMILES Cc1cccc2c3CCc4c[nH]nc4-c3[nH]c12 Show InChI InChI=1S/C14H13N3/c1-8-3-2-4-10-11-6-5-9-7-15-17-13(9)14(11)16-12(8)10/h2-4,7,16H,5-6H2,1H3,(H,15,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	760	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492963 (CHEMBL2414916) Show SMILES CCc1ccc2[nH]c-3c(CCc4c[nH]nc-34)c2c1 Show InChI InChI=1S/C15H15N3/c1-2-9-3-6-13-12(7-9)11-5-4-10-8-16-18-14(10)15(11)17-13/h3,6-8,17H,2,4-5H2,1H3,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	780	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492962 (CHEMBL2414981) Show SMILES CC1Cc2c([nH]c3ccccc23)-c2n[nH]cc12 Show InChI InChI=1S/C14H13N3/c1-8-6-10-9-4-2-3-5-12(9)16-13(10)14-11(8)7-15-17-14/h2-5,7-8,16H,6H2,1H3,(H,15,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492959 (CHEMBL2414982) Show SMILES Fc1cccc2c3CCc4c[nH]nc4-c3[nH]c12 Show InChI InChI=1S/C13H10FN3/c14-10-3-1-2-8-9-5-4-7-6-15-17-11(7)13(9)16-12(8)10/h1-3,6,16H,4-5H2,(H,15,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	860	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492949 (CHEMBL2414914) Show SMILES COc1cccc2[nH]c-3c(CCc4c[nH]nc-34)c12 Show InChI InChI=1S/C14H13N3O/c1-18-11-4-2-3-10-12(11)9-6-5-8-7-15-17-13(8)14(9)16-10/h2-4,7,16H,5-6H2,1H3,(H,15,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM24717 (3,4,16-triazatetracyclo[7.7.0.0^{2,6}.0^{10,15}]he...) Show SMILES OCc1[nH]nc-2c1CCc1c-2[nH]c2ccccc12 Show InChI InChI=1S/C14H13N3O/c18-7-12-10-6-5-9-8-3-1-2-4-11(8)15-13(9)14(10)17-16-12/h1-4,15,18H,5-7H2,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492960 (CHEMBL2414927) Show SMILES C1COc2cc3c4CCc5c[nH]nc5-c4[nH]c3cc2O1 Show InChI InChI=1S/C15H13N3O2/c1-2-9-10-5-12-13(20-4-3-19-12)6-11(10)17-15(9)14-8(1)7-16-18-14/h5-7,17H,1-4H2,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.64E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492953 (CHEMBL2414980) Show SMILES c1[nH]nc2c1ccc1c3ccccc3[nH]c21 Show InChI InChI=1S/C13H9N3/c1-2-4-11-9(3-1)10-6-5-8-7-14-16-12(8)13(10)15-11/h1-7,15H,(H,14,16)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.62E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM24716 (Tetrahydropyrazolo[3,4-a]carbazole, 25 | ethyl 3,4...) Show SMILES CCOC(=O)c1[nH]nc-2c1CCc1c-2[nH]c2ccccc12 Show InChI InChI=1S/C16H15N3O2/c1-2-21-16(20)15-11-8-7-10-9-5-3-4-6-12(9)17-13(10)14(11)18-19-15/h3-6,17H,2,7-8H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.86E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492954 (CHEMBL2414978) Show SMILES C1c2c[nH]nc2-c2[nH]c3ccccc3c12 Show InChI InChI=1S/C12H9N3/c1-2-4-10-8(3-1)9-5-7-6-13-15-11(7)12(9)14-10/h1-4,6,14H,5H2,(H,13,15)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.79E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50492950 (CHEMBL2414984) Show SMILES [O-][N+](=O)c1cccc2c3CCc4c[nH]nc4-c3[nH]c12 Show InChI InChI=1S/C13H10N4O2/c18-17(19)10-3-1-2-8-9-5-4-7-6-14-16-11(7)13(9)15-12(8)10/h1-3,6,15H,4-5H2,(H,14,16)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.32E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of RIP1/JNK2 (unknown origin)-mediated necrosis				Bioorg Med Chem Lett 23: 4903-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.073 BindingDB Entry DOI: 10.7270/Q2GB2702
					More data for this Ligand-Target Pair