Compile Data Set for Download or QSAR

Found 34 hits of ec50 for UniProtKB: P32240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101858 (4-(2-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxy-4-(3...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)c1 Show InChI InChI=1S/C23H32O6S/c1-29-15-17-5-2-4-16(12-17)13-18(24)7-8-19-20(22(26)14-21(19)25)9-11-30-10-3-6-23(27)28/h2,4-5,7-8,12,18-21,24-25H,3,6,9-11,13-15H2,1H3,(H,27,28)/b8-7+/t18-,19-,20-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50318871 (4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(=O)OC)c1 |r| Show InChI InChI=1S/C24H34O6S/c1-29-16-18-6-3-5-17(13-18)14-19(25)8-9-20-21(23(27)15-22(20)26)10-12-31-11-4-7-24(28)30-2/h3,5-6,8-9,13,19-22,25-26H,4,7,10-12,14-16H2,1-2H3/b9-8+/t19-,20-,21-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Agonist activity at mouse EP4 receptor expressed in CHO cells assessed as cAMP production				J Med Chem 53: 4332-53 (2010) Article DOI: 10.1021/jm9018756 BindingDB Entry DOI: 10.7270/Q21R6QPF
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101852 ((3-{(1R,2S,3R)-2-[(E)-(S)-4-(3-Ethoxymethyl-phenyl...) Show SMILES CCOCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2SCCCSCC(O)=O)c1 Show InChI InChI=1S/C23H32O6S2/c1-2-29-14-17-6-3-5-16(11-17)12-18(24)7-8-19-20(25)13-21(26)23(19)31-10-4-9-30-15-22(27)28/h3,5-8,11,18-20,23-25H,2,4,9-10,12-15H2,1H3,(H,27,28)/b8-7+/t18-,19+,20-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101847 (CHEMBL305568 | {3-[(1R,2S,3R)-3-Hydroxy-2-((E)-(S)...) Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2SCCCSCC(O)=O)c1 Show InChI InChI=1S/C21H28O5S2/c1-14-4-2-5-15(10-14)11-16(22)6-7-17-18(23)12-19(24)21(17)28-9-3-8-27-13-20(25)26/h2,4-7,10,16-18,21-23H,3,8-9,11-13H2,1H3,(H,25,26)/b7-6+/t16-,17+,18-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.80	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101851 ((3-{(1R,2S,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-(3...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2SCCCSCC(O)=O)c1 Show InChI InChI=1S/C22H30O6S2/c1-28-13-16-5-2-4-15(10-16)11-17(23)6-7-18-19(24)12-20(25)22(18)30-9-3-8-29-14-21(26)27/h2,4-7,10,17-19,22-24H,3,8-9,11-14H2,1H3,(H,26,27)/b7-6+/t17-,18+,19-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Evaluated for its competitive binding affinity towards mouse Prostanoid EP4 receptor in CHO cells expressing prostanoid receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101856 ((E)-7-{(1R,2R,3R,5R)-5-Chloro-3-hydroxy-2-[(E)-(S)...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)C[C@@H](Cl)[C@@H]2C\C=C\CCCC(O)=O)c1 Show InChI InChI=1S/C24H33ClO5/c1-30-16-18-8-6-7-17(13-18)14-19(26)11-12-21-20(22(25)15-23(21)27)9-4-2-3-5-10-24(28)29/h2,4,6-8,11-13,19-23,26-27H,3,5,9-10,14-16H2,1H3,(H,28,29)/b4-2+,12-11+/t19-,20-,21-,22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101861 (4-{(S)-2-[(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCSCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-6-14(20)8-9-15-16(18(22)13-17(15)21)10-12-25-11-5-7-19(23)24/h8-9,14-17,20-21H,2-7,10-13H2,1H3,(H,23,24)/b9-8+/t14-,15+,16+,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101836 (6-[(S)-(R)-3-Hydroxy-2-((1S,2R)-3-hydroxy-oct-1-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1SCCCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-5-8-14(20)10-11-15-16(21)13-17(22)19(15)25-12-7-4-6-9-18(23)24/h10-11,14-16,19-21H,2-9,12-13H2,1H3,(H,23,24)/b11-10+/t14-,15-,16+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.70	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101836 (6-[(S)-(R)-3-Hydroxy-2-((1S,2R)-3-hydroxy-oct-1-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1SCCCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-5-8-14(20)10-11-15-16(21)13-17(22)19(15)25-12-7-4-6-9-18(23)24/h10-11,14-16,19-21H,2-9,12-13H2,1H3,(H,23,24)/b11-10+/t14-,15-,16+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.70	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Evaluated for its competitive binding affinity towards mouse Prostanoid EP4 receptor in CHO cells expressing prostanoid receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101842 (CHEMBL64217 | {3-[(S)-(R)-3-Hydroxy-2-((1S,2R)-3-h...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1SCCCSCC(O)=O Show InChI InChI=1S/C18H30O5S2/c1-2-3-4-6-13(19)7-8-14-15(20)11-16(21)18(14)25-10-5-9-24-12-17(22)23/h7-8,13-15,18-20H,2-6,9-12H2,1H3,(H,22,23)/b8-7+/t13-,14-,15+,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.30	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Evaluated for its competitive binding affinity towards mouse Prostanoid EP4 receptor in CHO cells expressing prostanoid receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101846 ((3-{(1R,2S,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-(3...) Show SMILES CSCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2SCCCSCC(O)=O)c1 Show InChI InChI=1S/C22H30O5S3/c1-28-13-16-5-2-4-15(10-16)11-17(23)6-7-18-19(24)12-20(25)22(18)30-9-3-8-29-14-21(26)27/h2,4-7,10,17-19,22-24H,3,8-9,11-14H2,1H3,(H,26,27)/b7-6+/t17-,18+,19-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.80	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101850 (CHEMBL64254 | {3-[(S)-(R)-3-Hydroxy-2-((1S,2R)-3-h...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1SCCCOCC(O)=O Show InChI InChI=1S/C18H30O6S/c1-2-3-4-6-13(19)7-8-14-15(20)11-16(21)18(14)25-10-5-9-24-12-17(22)23/h7-8,13-15,18-20H,2-6,9-12H2,1H3,(H,22,23)/b8-7+/t13-,14-,15+,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	7.70	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101839 ((3-{(1R,2S,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-(3...) Show SMILES CCCOCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2SCCCSCC(O)=O)c1 Show InChI InChI=1S/C24H34O6S2/c1-2-9-30-15-18-6-3-5-17(12-18)13-19(25)7-8-20-21(26)14-22(27)24(20)32-11-4-10-31-16-23(28)29/h3,5-8,12,19-21,24-26H,2,4,9-11,13-16H2,1H3,(H,28,29)/b8-7+/t19-,20+,21-,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101845 (CHEMBL62779 | [3-((1R,2S,3R)-3-Hydroxy-2-{(E)-(S)-...) Show SMILES COCCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2SCCCSCC(O)=O)c1 Show InChI InChI=1S/C23H32O6S2/c1-29-9-8-16-4-2-5-17(12-16)13-18(24)6-7-19-20(25)14-21(26)23(19)31-11-3-10-30-15-22(27)28/h2,4-7,12,18-20,23-25H,3,8-11,13-15H2,1H3,(H,27,28)/b7-6+/t18-,19+,20-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101857 ((E)-7-{(1R,2R,3R,5R)-5-Fluoro-3-hydroxy-2-[(E)-(S)...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)C[C@@H](F)[C@@H]2C\C=C\CCCC(O)=O)c1 Show InChI InChI=1S/C24H33FO5/c1-30-16-18-8-6-7-17(13-18)14-19(26)11-12-21-20(22(25)15-23(21)27)9-4-2-3-5-10-24(28)29/h2,4,6-8,11-13,19-23,26-27H,3,5,9-10,14-16H2,1H3,(H,28,29)/b4-2+,12-11+/t19-,20-,21-,22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101864 (4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-...) Show SMILES Cc1cc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)ccc1O Show InChI InChI=1S/C22H30O6S/c1-14-11-15(4-7-19(14)24)12-16(23)5-6-17-18(21(26)13-20(17)25)8-10-29-9-2-3-22(27)28/h4-7,11,16-18,20,23-25H,2-3,8-10,12-13H2,1H3,(H,27,28)/b6-5+/t16-,17-,18-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101838 ((3-{(1R,2S,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-(4...) Show SMILES COc1ccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2SCCCSCC(O)=O)cc1 Show InChI InChI=1S/C21H28O6S2/c1-27-16-6-3-14(4-7-16)11-15(22)5-8-17-18(23)12-19(24)21(17)29-10-2-9-28-13-20(25)26/h3-8,15,17-18,21-23H,2,9-13H2,1H3,(H,25,26)/b8-5+/t15-,17+,18-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101843 (CHEMBL64542 | {3-[(1R,2S,3R)-3-Hydroxy-2-((E)-(S)-...) Show SMILES O[C@@H](Cc1ccccc1)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1SCCCSCC(O)=O Show InChI InChI=1S/C20H26O5S2/c21-15(11-14-5-2-1-3-6-14)7-8-16-17(22)12-18(23)20(16)27-10-4-9-26-13-19(24)25/h1-3,5-8,15-17,20-22H,4,9-13H2,(H,24,25)/b8-7+/t15-,16+,17-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101844 ((3-{(1R,2S,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-(3...) Show SMILES COc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2SCCCSCC(O)=O)c1 Show InChI InChI=1S/C21H28O6S2/c1-27-16-5-2-4-14(11-16)10-15(22)6-7-17-18(23)12-19(24)21(17)29-9-3-8-28-13-20(25)26/h2,4-7,11,15,17-18,21-23H,3,8-10,12-13H2,1H3,(H,25,26)/b7-6+/t15-,17+,18-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101835 (CHEMBL303532 | [3-((1R,2S,3R)-3-Hydroxy-2-{(E)-(S)...) Show SMILES COCCCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2SCCCSCC(O)=O)c1 Show InChI InChI=1S/C24H34O6S2/c1-30-10-3-7-17-5-2-6-18(13-17)14-19(25)8-9-20-21(26)15-22(27)24(20)32-12-4-11-31-16-23(28)29/h2,5-6,8-9,13,19-21,24-26H,3-4,7,10-12,14-16H2,1H3,(H,28,29)/b9-8+/t19-,20+,21-,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101865 ((E)-7-{(1R,2R,3R,5R)-5-Chloro-3-hydroxy-2-[(E)-(S)...) Show SMILES Cc1cc(C[C@H](O)\C=C\[C@H]2[C@H](O)C[C@@H](Cl)[C@@H]2C\C=C\CCCC(O)=O)ccc1O Show InChI InChI=1S/C23H31ClO5/c1-15-12-16(8-11-21(15)26)13-17(25)9-10-19-18(20(24)14-22(19)27)6-4-2-3-5-7-23(28)29/h2,4,8-12,17-20,22,25-27H,3,5-7,13-14H2,1H3,(H,28,29)/b4-2+,10-9+/t17-,18-,19-,20-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101860 (CHEMBL64188 | {(S)-4-[(R)-3-Hydroxy-2-((1R,2R)-3-h...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCSCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-7-14(20)9-10-16-15(17(21)12-18(16)22)8-5-6-11-25-13-19(23)24/h9-10,14-16,18,20,22H,2-8,11-13H2,1H3,(H,23,24)/b10-9+/t14-,15+,16+,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101855 (7-{(1R,2R,3R,5R)-5-Chloro-3-hydroxy-2-[(E)-(S)-3-h...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)C[C@@H](Cl)[C@@H]2CCCCCCC(O)=O)c1 Show InChI InChI=1S/C24H35ClO5/c1-30-16-18-8-6-7-17(13-18)14-19(26)11-12-21-20(22(25)15-23(21)27)9-4-2-3-5-10-24(28)29/h6-8,11-13,19-23,26-27H,2-5,9-10,14-16H2,1H3,(H,28,29)/b12-11+/t19-,20-,21-,22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101849 (3-{2-[(S)-(R)-3-Hydroxy-2-((1S,2R)-3-hydroxy-oct-1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1SCCSCCC(O)=O Show InChI InChI=1S/C18H30O5S2/c1-2-3-4-5-13(19)6-7-14-15(20)12-16(21)18(14)25-11-10-24-9-8-17(22)23/h6-7,13-15,18-20H,2-5,8-12H2,1H3,(H,22,23)/b7-6+/t13-,14-,15+,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101859 (4-(2-{(1R,2R,3R,5R)-5-Fluoro-3-hydroxy-2-[(E)-(S)-...) Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)C[C@@H](F)[C@@H]2CCSCCCC(O)=O)c1 Show InChI InChI=1S/C23H33FO5S/c1-29-15-17-5-2-4-16(12-17)13-18(25)7-8-20-19(21(24)14-22(20)26)9-11-30-10-3-6-23(27)28/h2,4-5,7-8,12,18-22,25-26H,3,6,9-11,13-15H2,1H3,(H,27,28)/b8-7+/t18-,19-,20-,21-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for human Prostanoid IP receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101854 (CHEMBL59921 | {3-[(1R,2S,3R)-3-Hydroxy-2-((E)-(S)-...) Show SMILES Cc1ccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2SCCCSCC(O)=O)cc1 Show InChI InChI=1S/C21H28O5S2/c1-14-3-5-15(6-4-14)11-16(22)7-8-17-18(23)12-19(24)21(17)28-10-2-9-27-13-20(25)26/h3-8,16-18,21-23H,2,9-13H2,1H3,(H,25,26)/b8-7+/t16-,17+,18-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101837 (CHEMBL303787 | {3-[(1R,2S,3R)-3-Hydroxy-2-((E)-(S)...) Show SMILES Cc1ccccc1C[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1SCCCSCC(O)=O Show InChI InChI=1S/C21H28O5S2/c1-14-5-2-3-6-15(14)11-16(22)7-8-17-18(23)12-19(24)21(17)28-10-4-9-27-13-20(25)26/h2-3,5-8,16-18,21-23H,4,9-13H2,1H3,(H,25,26)/b8-7+/t16-,17+,18-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101841 ((3-{(1R,2S,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-(2...) Show SMILES COc1ccccc1C[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1SCCCSCC(O)=O Show InChI InChI=1S/C21H28O6S2/c1-27-19-6-3-2-5-14(19)11-15(22)7-8-16-17(23)12-18(24)21(16)29-10-4-9-28-13-20(25)26/h2-3,5-8,15-17,21-23H,4,9-13H2,1H3,(H,25,26)/b8-7+/t15-,16+,17-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	580	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101863 (3-{(S)-3-[(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCSCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-6-14(20)8-9-16-15(17(21)13-18(16)22)7-5-11-25-12-10-19(23)24/h8-9,14-16,18,20,22H,2-7,10-13H2,1H3,(H,23,24)/b9-8+/t14-,15+,16+,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101862 (5-[(S)-(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1-en...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CSCCCCC(O)=O Show InChI InChI=1S/C19H32O5S/c1-2-3-4-7-14(20)9-10-15-16(18(22)12-17(15)21)13-25-11-6-5-8-19(23)24/h9-10,14-17,20-21H,2-8,11-13H2,1H3,(H,23,24)/b10-9+/t14-,15+,16+,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50101840 (CHEMBL64598 | {2-[(S)-(R)-3-Hydroxy-2-((1R,2R)-3-h...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CSCCSCC(O)=O Show InChI InChI=1S/C18H30O5S2/c1-2-3-4-5-13(19)6-7-14-15(17(21)10-16(14)20)11-24-8-9-25-12-18(22)23/h6-7,13-16,19-20H,2-5,8-12H2,1H3,(H,22,23)/b7-6+/t13-,14+,15+,16+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Evaluated for its competitive binding affinity towards mouse Prostanoid EP4 receptor in CHO cells expressing prostanoid receptor				Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D
					More data for this Ligand-Target Pair