Compile Data Set for Download or QSAR

Found 51 hits of ic50 for UniProtKB: P22199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (RAT)	BDBM50398061 (CHEMBL2181928) Show SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1 |r| Show InChI InChI=1S/C18H19N3O3/c1-12-9-21(14(10-23-12)13-5-3-2-4-6-13)16-8-7-15-18(19-16)20-17(22)11-24-15/h2-8,12,14H,9-11H2,1H3,(H,19,20,22)/t12-,14+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction in...				J Med Chem 61: 1086-1097 (2018) Article DOI: 10.1021/acs.jmedchem.7b01515 BindingDB Entry DOI: 10.7270/Q2V1277H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50531569 (CHEMBL4532472) Show SMILES NS(=O)(=O)C[C@H]1COc2cc(F)ccc2N1C(=O)c1ccc2OCC(=O)Nc2c1 |r| Show InChI InChI=1S/C18H16FN3O6S/c19-11-2-3-14-16(6-11)27-7-12(9-29(20,25)26)22(14)18(24)10-1-4-15-13(5-10)21-17(23)8-28-15/h1-6,12H,7-9H2,(H,21,23)(H2,20,25,26)/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assay				J Med Chem 62: 1385-1406 (2019) Article DOI: 10.1021/acs.jmedchem.8b01523 BindingDB Entry DOI: 10.7270/Q2GT5RP6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mineralocorticoid receptor (RAT)	BDBM404273 (US10017502, Example 6b) Show SMILES CNC(=O)C[C@H]1COc2cc(Cl)ccc2N1C(=O)c1ccc2OCC(=O)Nc2c1 |r| Show InChI InChI=1S/C20H18ClN3O5/c1-22-18(25)8-13-9-28-17-7-12(21)3-4-15(17)24(13)20(27)11-2-5-16-14(6-11)23-19(26)10-29-16/h2-7,13H,8-10H2,1H3,(H,22,25)(H,23,26)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assay				J Med Chem 62: 1385-1406 (2019) Article DOI: 10.1021/acs.jmedchem.8b01523 BindingDB Entry DOI: 10.7270/Q2GT5RP6
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50398062 (CHEMBL2181930) Show SMILES CC1(C)OC(=S)Nc2ccc(NS(=O)(=O)c3cccs3)cc12 Show InChI InChI=1S/C14H14N2O3S3/c1-14(2)10-8-9(5-6-11(10)15-13(20)19-14)16-22(17,18)12-4-3-7-21-12/h3-8,16H,1-2H3,(H,15,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in rat kidney cytosolic fraction measured after 18 hrs by liquid scintillation counting method				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50398062 (CHEMBL2181930) Show SMILES CC1(C)OC(=S)Nc2ccc(NS(=O)(=O)c3cccs3)cc12 Show InChI InChI=1S/C14H14N2O3S3/c1-14(2)10-8-9(5-6-11(10)15-13(20)19-14)16-22(17,18)12-4-3-7-21-12/h3-8,16H,1-2H3,(H,15,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-aldosterone from rat mineralocorticoid receptor after 18 hrs by liquid scintillation counter analysis				J Med Chem 55: 7957-66 (2012) Article DOI: 10.1021/jm300806c BindingDB Entry DOI: 10.7270/Q2QC04N3
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50398060 (CHEMBL2181931) Show SMILES COc1cc(ccc1S(N)(=O)=O)C(=O)Nc1ccc(c(CCN(C)C2CC2)c1)-c1ccccc1OC(F)(F)F Show InChI InChI=1S/C27H28F3N3O5S/c1-33(20-9-10-20)14-13-17-15-19(8-11-21(17)22-5-3-4-6-23(22)38-27(28,29)30)32-26(34)18-7-12-25(39(31,35)36)24(16-18)37-2/h3-8,11-12,15-16,20H,9-10,13-14H2,1-2H3,(H,32,34)(H2,31,35,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Aldosterone C from rat mineralocorticoid receptor by liquid scintillation counter analysis				J Med Chem 55: 7957-66 (2012) Article DOI: 10.1021/jm300806c BindingDB Entry DOI: 10.7270/Q2QC04N3
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50235950 (CHEMBL4087750) Show SMILES COc1cc(NC(=O)c2ccc(c(CCN(C)C3CC3)c2)-c2ccccc2OC(F)(F)F)ccc1S(N)(=O)=O Show InChI InChI=1S/C27H28F3N3O5S/c1-33(20-9-10-20)14-13-17-15-18(7-11-21(17)22-5-3-4-6-23(22)38-27(28,29)30)26(34)32-19-8-12-25(39(31,35)36)24(16-19)37-2/h3-8,11-12,15-16,20H,9-10,13-14H2,1-2H3,(H,32,34)(H2,31,35,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50235982 (CHEMBL4085281) Show SMILES COc1cc(NC(=O)c2ccc(c(COC(C)=O)c2)-c2ccccc2C(F)(F)F)ccc1S(N)(=O)=O Show InChI InChI=1S/C24H21F3N2O6S/c1-14(30)35-13-16-11-15(7-9-18(16)19-5-3-4-6-20(19)24(25,26)27)23(31)29-17-8-10-22(36(28,32)33)21(12-17)34-2/h3-12H,13H2,1-2H3,(H,29,31)(H2,28,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50318300 (CHEMBL1095097 | EPLERENONE | SC-66110) Show SMILES COC(=O)[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@@]23O[C@@H]2C[C@@]2(C)[C@@H](CC[C@@]22CCC(=O)O2)[C@H]13 |r,t:6| Show InChI InChI=1S/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17-,19+,21+,22+,23-,24-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assay				J Med Chem 62: 1385-1406 (2019) Article DOI: 10.1021/acs.jmedchem.8b01523 BindingDB Entry DOI: 10.7270/Q2GT5RP6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mineralocorticoid receptor (RAT)	BDBM19214 ((1S,2R,10S,11S,14S,15R,17S)-17-hydroxy-14-(2-hydro...) Show SMILES [H][C@@]12CC[C@H](C(=O)CO)[C@]1(C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C)C=O |t:21| Show InChI InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Aldo from mineralocorticoid receptor in Sprague-Dawley rat kidney after 2 hrs by liquid scintillation counting				Bioorg Med Chem Lett 21: 6310-3 (2011) Checked by Author Article DOI: 10.1016/j.bmcl.2011.08.118 BindingDB Entry DOI: 10.7270/Q2JH3MKZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mineralocorticoid receptor (RAT)	BDBM19214 ((1S,2R,10S,11S,14S,15R,17S)-17-hydroxy-14-(2-hydro...) Show SMILES [H][C@@]12CC[C@H](C(=O)CO)[C@]1(C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C)C=O |t:21| Show InChI InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from Sprague-Dawley rat MR by liquid scintillation counting				Bioorg Med Chem Lett 21: 1744-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.073 BindingDB Entry DOI: 10.7270/Q2474B55
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mineralocorticoid receptor (RAT)	BDBM50235983 (CHEMBL4095450) Show SMILES COc1cc(NC(=O)c2ccc(c(CO)c2)-c2ccccc2OC(F)(F)F)ccc1S(N)(=O)=O Show InChI InChI=1S/C22H19F3N2O6S/c1-32-19-11-15(7-9-20(19)34(26,30)31)27-21(29)13-6-8-16(14(10-13)12-28)17-4-2-3-5-18(17)33-22(23,24)25/h2-11,28H,12H2,1H3,(H,27,29)(H2,26,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50235951 (CHEMBL4066419) Show SMILES COc1cc(NC(=O)c2ccc(c(CCN3CC(C)OC(C)C3)c2)-c2ccccc2OC(F)(F)F)ccc1S(N)(=O)=O Show InChI InChI=1S/C29H32F3N3O6S/c1-18-16-35(17-19(2)40-18)13-12-20-14-21(8-10-23(20)24-6-4-5-7-25(24)41-29(30,31)32)28(36)34-22-9-11-27(42(33,37)38)26(15-22)39-3/h4-11,14-15,18-19H,12-13,16-17H2,1-3H3,(H,34,36)(H2,33,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50531586 (CHEMBL4462110) Show SMILES CNC(=O)C[C@H]1COc2ccc(Cl)cc2N1C(=O)c1ccc2OCC(=O)Nc2c1 |r| Show InChI InChI=1S/C20H18ClN3O5/c1-22-18(25)8-13-9-28-17-5-3-12(21)7-15(17)24(13)20(27)11-2-4-16-14(6-11)23-19(26)10-29-16/h2-7,13H,8-10H2,1H3,(H,22,25)(H,23,26)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assay				J Med Chem 62: 1385-1406 (2019) Article DOI: 10.1021/acs.jmedchem.8b01523 BindingDB Entry DOI: 10.7270/Q2GT5RP6
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM238159 (US10017502, Example 4b | US9394291, 4a) Show SMILES CNC(=O)C[C@H]1COc2cc(F)ccc2N1C(=O)c1ccc2OCC(=O)Nc2c1 |r| Show InChI InChI=1S/C20H18FN3O5/c1-22-18(25)8-13-9-28-17-7-12(21)3-4-15(17)24(13)20(27)11-2-5-16-14(6-11)23-19(26)10-29-16/h2-7,13H,8-10H2,1H3,(H,22,25)(H,23,26)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assay				J Med Chem 62: 1385-1406 (2019) Article DOI: 10.1021/acs.jmedchem.8b01523 BindingDB Entry DOI: 10.7270/Q2GT5RP6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mineralocorticoid receptor (RAT)	BDBM50235954 (CHEMBL4075017) Show SMILES COc1cc(NC(=O)c2ccc(c(CO)c2)-c2ccccc2-c2cccs2)ccc1S(N)(=O)=O Show InChI InChI=1S/C25H22N2O5S2/c1-32-22-14-18(9-11-24(22)34(26,30)31)27-25(29)16-8-10-19(17(13-16)15-28)20-5-2-3-6-21(20)23-7-4-12-33-23/h2-14,28H,15H2,1H3,(H,27,29)(H2,26,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50235952 (CHEMBL4079872) Show SMILES CCOCc1cc(NC(=O)c2ccc(c(OC)c2)S(N)(=O)=O)ccc1-c1ccccc1C(F)(F)F Show InChI InChI=1S/C24H23F3N2O5S/c1-3-34-14-16-12-17(9-10-18(16)19-6-4-5-7-20(19)24(25,26)27)29-23(30)15-8-11-22(35(28,31)32)21(13-15)33-2/h4-13H,3,14H2,1-2H3,(H,29,30)(H2,28,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50531568 (CHEMBL4455600) Show SMILES NC(=O)C[C@H]1COc2cc(F)cc(F)c2N1C(=O)c1ccc2OCC(=O)Nc2c1 |r| Show InChI InChI=1S/C19H15F2N3O5/c20-10-4-12(21)18-15(5-10)28-7-11(6-16(22)25)24(18)19(27)9-1-2-14-13(3-9)23-17(26)8-29-14/h1-5,11H,6-8H2,(H2,22,25)(H,23,26)/t11-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assay				J Med Chem 62: 1385-1406 (2019) Article DOI: 10.1021/acs.jmedchem.8b01523 BindingDB Entry DOI: 10.7270/Q2GT5RP6
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50531567 (CHEMBL4557032) Show SMILES C[C@H]1COc2cc(F)ccc2N1C(=O)c1ccc2OCC(=O)Nc2c1 |r| Show InChI InChI=1S/C18H15FN2O4/c1-10-8-24-16-7-12(19)3-4-14(16)21(10)18(23)11-2-5-15-13(6-11)20-17(22)9-25-15/h2-7,10H,8-9H2,1H3,(H,20,22)/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assay				J Med Chem 62: 1385-1406 (2019) Article DOI: 10.1021/acs.jmedchem.8b01523 BindingDB Entry DOI: 10.7270/Q2GT5RP6
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50004519 (CHEMBL2181929) Show SMILES CC1(C)Oc2cc(NS(C)(=O)=O)ccc2N(C1=O)c1ccc(F)cc1 Show InChI InChI=1S/C17H17FN2O4S/c1-17(2)16(21)20(13-7-4-11(18)5-8-13)14-9-6-12(10-15(14)24-17)19-25(3,22)23/h4-10,19H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to rat mineralocorticoid receptor				J Med Chem 55: 7957-66 (2012) Article DOI: 10.1021/jm300806c BindingDB Entry DOI: 10.7270/Q2QC04N3
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50235976 (CHEMBL4060780) Show SMILES CC1(C)Oc2cc(NS(C)(=O)=O)ccc2C(=N1)c1ccc(Cl)cc1 |c:16| Show InChI InChI=1S/C17H17ClN2O3S/c1-17(2)19-16(11-4-6-12(18)7-5-11)14-9-8-13(10-15(14)23-17)20-24(3,21)22/h4-10,20H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in Sprague-Dawley rat kidney cytosolic fraction measured after overnight incubation by liquid scintillation ...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50235977 (CHEMBL4082663) Show SMILES Cc1cc(NS(C)(=O)=O)cc2OC(C)(C)N=C(c3ccc(F)cc3)c12 |t:15| Show InChI InChI=1S/C18H19FN2O3S/c1-11-9-14(21-25(4,22)23)10-15-16(11)17(20-18(2,3)24-15)12-5-7-13(19)8-6-12/h5-10,21H,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Inhibition of Ha-ras polymerase-chain reaction product				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50235978 (CHEMBL4064627) Show SMILES CC1=C(c2ccc(F)cc2)c2ccc(NS(C)(=O)=O)cc2OC1(C)C |c:1| Show InChI InChI=1S/C19H20FNO3S/c1-12-18(13-5-7-14(20)8-6-13)16-10-9-15(21-25(4,22)23)11-17(16)24-19(12,2)3/h5-11,21H,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in Sprague-Dawley rat kidney cytosolic fraction measured after overnight incubation by liquid scintillation ...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50235979 (CHEMBL4086138) Show SMILES Cc1cc(Cl)ccc1C1=CC(C)(C)Oc2cc(NS(C)(=O)=O)ccc12 |t:9| Show InChI InChI=1S/C19H20ClNO3S/c1-12-9-13(20)5-7-15(12)17-11-19(2,3)24-18-10-14(6-8-16(17)18)21-25(4,22)23/h5-11,21H,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in Sprague-Dawley rat kidney cytosolic fraction measured after overnight incubation by liquid scintillation ...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50336275 (1-oxo-1,3,4,5,6,7,8,9-octahydrobenzo[c][1]oxacyclo...) Show SMILES CC(=O)Oc1cc2CCCCCCCOC(=O)c2c(OC(C)=O)c1 Show InChI InChI=1S/C18H22O6/c1-12(19)23-15-10-14-8-6-4-3-5-7-9-22-18(21)17(14)16(11-15)24-13(2)20/h10-11H,3-9H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...				Bioorg Med Chem Lett 21: 1171-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.101 BindingDB Entry DOI: 10.7270/Q2X92BKM
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50336276 (1-oxo-1,3,4,5,6,7,8,9,10,11-decahydrobenzo[c][1]ox...) Show SMILES CC(=O)Oc1cc2CCCCCCCCCOC(=O)c2c(OC(C)=O)c1 Show InChI InChI=1S/C20H26O6/c1-14(21)25-17-12-16-10-8-6-4-3-5-7-9-11-24-20(23)19(16)18(13-17)26-15(2)22/h12-13H,3-11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...				Bioorg Med Chem Lett 21: 1171-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.101 BindingDB Entry DOI: 10.7270/Q2X92BKM
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50336277 (1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-benzo[c][1]oxa...) Show SMILES CC(=O)Oc1cc2CCCCCCCCOC(=O)c2c(OC(C)=O)c1 Show InChI InChI=1S/C19H24O6/c1-13(20)24-16-11-15-9-7-5-3-4-6-8-10-23-19(22)18(15)17(12-16)25-14(2)21/h11-12H,3-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...				Bioorg Med Chem Lett 21: 1171-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.101 BindingDB Entry DOI: 10.7270/Q2X92BKM
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM18161 ((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C |r| Show InChI InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Aldo from mineralocorticoid receptor in Sprague-Dawley rat kidney after 2 hrs by liquid scintillation counting				Bioorg Med Chem Lett 21: 6310-3 (2011) Checked by Author Article DOI: 10.1016/j.bmcl.2011.08.118 BindingDB Entry DOI: 10.7270/Q2JH3MKZ
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM18161 ((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C |r| Show InChI InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from Sprague-Dawley rat MR by liquid scintillation counting				Bioorg Med Chem Lett 21: 1744-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.073 BindingDB Entry DOI: 10.7270/Q2474B55
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50336278 ((R)-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-b...) Show SMILES C[C@@H]1CCCCCCCc2cc(OC(C)=O)cc(OC(C)=O)c2C(=O)O1 |r| Show InChI InChI=1S/C20H26O6/c1-13-9-7-5-4-6-8-10-16-11-17(25-14(2)21)12-18(26-15(3)22)19(16)20(23)24-13/h11-13H,4-10H2,1-3H3/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...				Bioorg Med Chem Lett 21: 1171-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.101 BindingDB Entry DOI: 10.7270/Q2X92BKM
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50336274 (1-oxo-3,4,5,6,7,8,9,10,11,12-decahydro-1H-benzo[c]...) Show SMILES CC(=O)Oc1cc2CCCCCCCCCCOC(=O)c2c(OC(C)=O)c1 Show InChI InChI=1S/C21H28O6/c1-15(22)26-18-13-17-11-9-7-5-3-4-6-8-10-12-25-21(24)20(17)19(14-18)27-16(2)23/h13-14H,3-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...				Bioorg Med Chem Lett 21: 1171-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.101 BindingDB Entry DOI: 10.7270/Q2X92BKM
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM19207 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@@H](O)CCC=C |r,t:5| Show InChI InChI=1S/C23H27FN2O/c1-3-4-8-22(27)20-7-5-6-17-13-21-16(14-23(17,20)2)15-25-26(21)19-11-9-18(24)10-12-19/h3,9-13,15,20,22,27H,1,4-8,14H2,2H3/t20-,22+,23+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The IC50s were determined by incubating the receptors with radiolabeled aldosterone in the presence of full log scale concentrations (10-11 M to 10-6...				J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM19201 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@](C)(O)c1ccc(F)cc1 |r,t:5| Show InChI InChI=1S/C26H26F2N2O/c1-25-15-17-16-29-30(22-12-10-21(28)11-13-22)23(17)14-19(25)4-3-5-24(25)26(2,31)18-6-8-20(27)9-7-18/h6-14,16,24,31H,3-5,15H2,1-2H3/t24-,25-,26+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The IC50s were determined by incubating the receptors with radiolabeled aldosterone in the presence of full log scale concentrations (10-11 M to 10-6...				J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM19200 ((S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@H](O)c1ccc(F)cc1 |r,t:5| Show InChI InChI=1S/C25H24F2N2O/c1-25-14-17-15-28-29(21-11-9-20(27)10-12-21)23(17)13-18(25)3-2-4-22(25)24(30)16-5-7-19(26)8-6-16/h5-13,15,22,24,30H,2-4,14H2,1H3/t22-,24-,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The IC50s were determined by incubating the receptors with radiolabeled aldosterone in the presence of full log scale concentrations (10-11 M to 10-6...				J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM19199 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@@H](O)c1cc(F)c(F)c(OC)c1 |r,t:5| Show InChI InChI=1S/C26H25F3N2O2/c1-26-13-16-14-30-31(19-8-6-18(27)7-9-19)22(16)12-17(26)4-3-5-20(26)25(32)15-10-21(28)24(29)23(11-15)33-2/h6-12,14,20,25,32H,3-5,13H2,1-2H3/t20-,25+,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The IC50s were determined by incubating the receptors with radiolabeled aldosterone in the presence of full log scale concentrations (10-11 M to 10-6...				J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM19191 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@@H](O)c1ccccc1 |r,t:5| Show InChI InChI=1S/C25H25FN2O/c1-25-15-18-16-27-28(21-12-10-20(26)11-13-21)23(18)14-19(25)8-5-9-22(25)24(29)17-6-3-2-4-7-17/h2-4,6-7,10-14,16,22,24,29H,5,8-9,15H2,1H3/t22-,24+,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The IC50s were determined by incubating the receptors with radiolabeled aldosterone in the presence of full log scale concentrations (10-11 M to 10-6...				J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM19192 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@@H](O)c1ccc(F)cc1 |r,t:5| Show InChI InChI=1S/C25H24F2N2O/c1-25-14-17-15-28-29(21-11-9-20(27)10-12-21)23(17)13-18(25)3-2-4-22(25)24(30)16-5-7-19(26)8-6-16/h5-13,15,22,24,30H,2-4,14H2,1H3/t22-,24+,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The IC50s were determined by incubating the receptors with radiolabeled aldosterone in the presence of full log scale concentrations (10-11 M to 10-6...				J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50338693 (2-methyl-2-((3aR,4S,9bS)-8-nitro-3a,4,5,9b-tetrahy...) Show SMILES CC(C)(CO)[C@H]1Nc2ccc(cc2[C@H]2C=CC[C@@H]12)[N+]([O-])=O |r,c:15| Show InChI InChI=1S/C16H20N2O3/c1-16(2,9-19)15-12-5-3-4-11(12)13-8-10(18(20)21)6-7-14(13)17-15/h3-4,6-8,11-12,15,17,19H,5,9H2,1-2H3/t11-,12+,15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from Sprague-Dawley rat MR by liquid scintillation counting				Bioorg Med Chem Lett 21: 1744-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.073 BindingDB Entry DOI: 10.7270/Q2474B55
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50336279 ((R)-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-b...) Show SMILES C[C@@H]1CCCCCCCc2cc(OS(=O)(=O)c3ccc(C)cc3)cc(OS(=O)(=O)c3ccc(C)cc3)c2C(=O)O1 |r| Show InChI InChI=1S/C30H34O8S2/c1-21-11-15-26(16-12-21)39(32,33)37-25-19-24-10-8-6-4-5-7-9-23(3)36-30(31)29(24)28(20-25)38-40(34,35)27-17-13-22(2)14-18-27/h11-20,23H,4-10H2,1-3H3/t23-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...				Bioorg Med Chem Lett 21: 1171-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.101 BindingDB Entry DOI: 10.7270/Q2X92BKM
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50167799 (1-(4-fluorophenyl)-4a-methyl-4',5'-divinyl-(4'R,4a...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCCC21O[C@H](C=C)[C@H](O1)C=C)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C24H25FN2O2/c1-4-21-22(5-2)29-24(28-21)12-6-7-17-13-20-16(14-23(17,24)3)15-26-27(20)19-10-8-18(25)9-11-19/h4-5,8-11,13,15,21-22H,1-2,6-7,12,14H2,3H3/t21-,22-,23+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for rat mineralocorticoid receptor				Bioorg Med Chem Lett 15: 2926-31 (2005) Article DOI: 10.1016/j.bmcl.2005.03.027 BindingDB Entry DOI: 10.7270/Q2X34X0Q
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50167808 (1-(4-fluorophenyl)-4a-methyl-(4aS)-spiro[4,4a,5,6,...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCCC21OCCO1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C20H21FN2O2/c1-19-12-14-13-22-23(17-6-4-16(21)5-7-17)18(14)11-15(19)3-2-8-20(19)24-9-10-25-20/h4-7,11,13H,2-3,8-10,12H2,1H3/t19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for rat mineralocorticoid receptor				Bioorg Med Chem Lett 15: 2926-31 (2005) Article DOI: 10.1016/j.bmcl.2005.03.027 BindingDB Entry DOI: 10.7270/Q2X34X0Q
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50336280 ((R)-de-O-methyllasioplodin | CHEMBL1669749) Show SMILES C[C@@H]1CCCCCCCc2cc(O)cc(O)c2C(=O)O1 |r| Show InChI InChI=1S/C16H22O4/c1-11-7-5-3-2-4-6-8-12-9-13(17)10-14(18)15(12)16(19)20-11/h9-11,17-18H,2-8H2,1H3/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...				Bioorg Med Chem Lett 21: 1171-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.101 BindingDB Entry DOI: 10.7270/Q2X92BKM
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50167790 (1-(4-fluorophenyl)-4',4a,6'-trimethyl-(4'S,4aS,6'S...) Show SMILES C[C@H]1C[C@H](C)O[C@@]2(CCC3=Cc4c(C[C@]23C)cnn4-c2ccc(F)cc2)O1 |t:9| Show InChI InChI=1S/C22H25FN2O2/c1-14-10-15(2)27-22(26-14)9-8-17-11-20-16(12-21(17,22)3)13-24-25(20)19-6-4-18(23)5-7-19/h4-7,11,13-15H,8-10,12H2,1-3H3/t14-,15-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for rat mineralocorticoid receptor				Bioorg Med Chem Lett 15: 2926-31 (2005) Article DOI: 10.1016/j.bmcl.2005.03.027 BindingDB Entry DOI: 10.7270/Q2X34X0Q
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50167795 (1-(4-fluorophenyl)-4',4a,5'-trimethyl-(4'R,4aS,5'R...) Show SMILES C[C@H]1OC2(CCC3=Cc4c(C[C@]23C)cnn4-c2ccc(F)cc2)O[C@@H]1C |t:6| Show InChI InChI=1S/C21H23FN2O2/c1-13-14(2)26-21(25-13)9-8-16-10-19-15(11-20(16,21)3)12-23-24(19)18-6-4-17(22)5-7-18/h4-7,10,12-14H,8-9,11H2,1-3H3/t13-,14-,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for rat mineralocorticoid receptor				Bioorg Med Chem Lett 15: 2926-31 (2005) Article DOI: 10.1016/j.bmcl.2005.03.027 BindingDB Entry DOI: 10.7270/Q2X34X0Q
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50167794 (1-(4-fluorophenyl)-4a-methyl-(4aS)-spiro[1,4,4a,5,...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC21OCCO1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C19H19FN2O2/c1-18-11-13-12-21-22(16-4-2-15(20)3-5-16)17(13)10-14(18)6-7-19(18)23-8-9-24-19/h2-5,10,12H,6-9,11H2,1H3/t18-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for rat mineralocorticoid receptor				Bioorg Med Chem Lett 15: 2926-31 (2005) Article DOI: 10.1016/j.bmcl.2005.03.027 BindingDB Entry DOI: 10.7270/Q2X34X0Q
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50167796 (1-(4-fluorophenyl)-4a-methyl-4',5'-divinyl-(4'R,4a...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC21O[C@H](C=C)[C@H](O1)C=C)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C23H23FN2O2/c1-4-20-21(5-2)28-23(27-20)11-10-16-12-19-15(13-22(16,23)3)14-25-26(19)18-8-6-17(24)7-9-18/h4-9,12,14,20-21H,1-2,10-11,13H2,3H3/t20-,21-,22+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for rat mineralocorticoid receptor				Bioorg Med Chem Lett 15: 2926-31 (2005) Article DOI: 10.1016/j.bmcl.2005.03.027 BindingDB Entry DOI: 10.7270/Q2X34X0Q
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50355936 (CHEMBL1910411) Show SMILES CN(C)[C@H]1C[C@H](Nc2ccc(cc12)[N+]([O-])=O)C(C)(C)CO |r| Show InChI InChI=1S/C15H23N3O3/c1-15(2,9-19)14-8-13(17(3)4)11-7-10(18(20)21)5-6-12(11)16-14/h5-7,13-14,16,19H,8-9H2,1-4H3/t13-,14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Aldo from mineralocorticoid receptor in Sprague-Dawley rat kidney after 2 hrs by liquid scintillation counting				Bioorg Med Chem Lett 21: 6310-3 (2011) Checked by Author Article DOI: 10.1016/j.bmcl.2011.08.118 BindingDB Entry DOI: 10.7270/Q2JH3MKZ
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50336281 ((R,Z)-12,14-dimethoxy-3-methyl-3,4,5,6,9,10-hexahy...) Show SMILES COc1cc2CC\C=C/CCC[C@@H](C)OC(=O)c2c(OC)c1 |r,c:7| Show InChI InChI=1S/C18H24O4/c1-13-9-7-5-4-6-8-10-14-11-15(20-2)12-16(21-3)17(14)18(19)22-13/h4,6,11-13H,5,7-10H2,1-3H3/b6-4-/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...				Bioorg Med Chem Lett 21: 1171-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.101 BindingDB Entry DOI: 10.7270/Q2X92BKM
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM50336282 ((R)-3-methyl-1-oxo-3,4,5,6,7,8,9,10-octahydro-1H-b...) Show SMILES CCC(=O)Oc1cc2CCCCCCC[C@@H](C)OC(=O)c2c(OC(=O)CC)c1 |r| Show InChI InChI=1S/C22H30O6/c1-4-19(23)27-17-13-16-12-10-8-6-7-9-11-15(3)26-22(25)21(16)18(14-17)28-20(24)5-2/h13-15H,4-12H2,1-3H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...				Bioorg Med Chem Lett 21: 1171-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.101 BindingDB Entry DOI: 10.7270/Q2X92BKM
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (RAT)	BDBM18525 (Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...) Show SMILES CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kaken Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Aldo from mineralocorticoid receptor in Sprague-Dawley rat kidney after 2 hrs by liquid scintillation counting				Bioorg Med Chem Lett 21: 6310-3 (2011) Checked by Author Article DOI: 10.1016/j.bmcl.2011.08.118 BindingDB Entry DOI: 10.7270/Q2JH3MKZ
					More data for this Ligand-Target Pair

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