Compile Data Set for Download or QSAR

Found 8 hits of ic50 for UniProtKB: P49058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase (Borrelia burgdorferi)	BDBM81426 (1H-naphtho[2,3-d]imidazol-2-ylmethyl 4-aminobenzoa...) Show SMILES Nc1ccc(cc1)C(=O)OCc1nc2cc3ccccc3cc2[nH]1 Show InChI InChI=1S/C19H15N3O2/c20-15-7-5-12(6-8-15)19(23)24-11-18-21-16-9-13-3-1-2-4-14(13)10-17(16)22-18/h1-10H,11,20H2,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).				Chem Biol 17: 1084-91 (2010) Article DOI: 10.1016/j.chembiol.2010.07.014 BindingDB Entry DOI: 10.7270/Q2GH9GF5
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Borrelia burgdorferi)	BDBM81423 (N-(4-methoxyphenyl)-2-[2-(1,3-thiazol-4-yl)-1H-1,3...) Show SMILES COc1ccc(NC(=O)Cn2c(nc3ccccc23)-c2cscn2)cc1 Show InChI InChI=1S/C19H16N4O2S/c1-25-14-8-6-13(7-9-14)21-18(24)10-23-17-5-3-2-4-15(17)22-19(23)16-11-26-12-20-16/h2-9,11-12H,10H2,1H3,(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).				Chem Biol 17: 1084-91 (2010) Article DOI: 10.1016/j.chembiol.2010.07.014 BindingDB Entry DOI: 10.7270/Q2GH9GF5
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Borrelia burgdorferi)	BDBM81425 (l-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl}sulfanyl...) Show SMILES CCn1c(SCC(=O)Nc2ccc(OC)cc2)nc2ccsc2c1=O Show InChI InChI=1S/C17H17N3O3S2/c1-3-20-16(22)15-13(8-9-24-15)19-17(20)25-10-14(21)18-11-4-6-12(23-2)7-5-11/h4-9H,3,10H2,1-2H3,(H,18,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).				Chem Biol 17: 1084-91 (2010) Article DOI: 10.1016/j.chembiol.2010.07.014 BindingDB Entry DOI: 10.7270/Q2GH9GF5
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Borrelia burgdorferi)	BDBM81427 (3-{1H-naphtho[2,3-d]imidazol-2-yl}propyl 4-aminobe...) Show SMILES Nc1ccc(cc1)C(=O)OCCCc1nc2cc3ccccc3cc2[nH]1 Show InChI InChI=1S/C21H19N3O2/c22-17-9-7-14(8-10-17)21(25)26-11-3-6-20-23-18-12-15-4-1-2-5-16(15)13-19(18)24-20/h1-2,4-5,7-10,12-13H,3,6,11,22H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).				Chem Biol 17: 1084-91 (2010) Article DOI: 10.1016/j.chembiol.2010.07.014 BindingDB Entry DOI: 10.7270/Q2GH9GF5
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Borrelia burgdorferi)	BDBM81328 (methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...) Show SMILES COC(=O)c1c(C)c(=O)[nH]c2ccccc12 Show InChI InChI=1S/C12H11NO3/c1-7-10(12(15)16-2)8-5-3-4-6-9(8)13-11(7)14/h3-6H,1-2H3,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).				Chem Biol 17: 1084-91 (2010) Article DOI: 10.1016/j.chembiol.2010.07.014 BindingDB Entry DOI: 10.7270/Q2GH9GF5
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Borrelia burgdorferi)	BDBM50294184 (CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClNO2/c1-11(19-14-5-3-2-4-6-14)15(18)17-13-9-7-12(16)8-10-13/h2-11H,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).				Chem Biol 17: 1084-91 (2010) Article DOI: 10.1016/j.chembiol.2010.07.014 BindingDB Entry DOI: 10.7270/Q2GH9GF5
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Borrelia burgdorferi)	BDBM81424 (N-(4-methoxyphenyl)-2-(3-methyl-4-oxo-3,4-dihydrop...) Show SMILES COc1ccc(NC(=O)Cc2nn(C)c(=O)c3ccccc23)cc1 Show InChI InChI=1S/C18H17N3O3/c1-21-18(23)15-6-4-3-5-14(15)16(20-21)11-17(22)19-12-7-9-13(24-2)10-8-12/h3-10H,11H2,1-2H3,(H,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).				Chem Biol 17: 1084-91 (2010) Article DOI: 10.1016/j.chembiol.2010.07.014 BindingDB Entry DOI: 10.7270/Q2GH9GF5
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Borrelia burgdorferi)	BDBM81422 (N-(4-methoxyphenyl)-2-(naphthalen-1-yl)acetamide, ...) Show SMILES COc1ccc(NC(=O)Cc2cccc3ccccc23)cc1 Show InChI InChI=1S/C19H17NO2/c1-22-17-11-9-16(10-12-17)20-19(21)13-15-7-4-6-14-5-2-3-8-18(14)15/h2-12H,13H2,1H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).				Chem Biol 17: 1084-91 (2010) Article DOI: 10.1016/j.chembiol.2010.07.014 BindingDB Entry DOI: 10.7270/Q2GH9GF5
					More data for this Ligand-Target Pair