Compile Data Set for Download or QSAR

Found 35 hits of ic50 for UniProtKB: P03072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Large T antigen (JC polyomavirus)	BDBM50533446 (CHEMBL4460953) Show SMILES CC(=O)Nc1ccc(Oc2ncccc2-c2nc3ccncc3s2)cc1 Show InChI InChI=1S/C19H14N4O2S/c1-12(24)22-13-4-6-14(7-5-13)25-18-15(3-2-9-21-18)19-23-16-8-10-20-11-17(16)26-19/h2-11H,1H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533445 (CHEMBL4531456) Show SMILES CC(=O)Nc1ccc(Oc2ccccc2-c2nc3ccncc3s2)cc1 Show InChI InChI=1S/C20H15N3O2S/c1-13(24)22-14-6-8-15(9-7-14)25-18-5-3-2-4-16(18)20-23-17-10-11-21-12-19(17)26-20/h2-12H,1H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair				3D Structure (crystal)
Large T antigen (JC polyomavirus)	BDBM50533444 (CHEMBL4519588) Show SMILES O(c1ccccc1)c1ncccc1-c1nc2ccncc2s1 Show InChI InChI=1S/C17H11N3OS/c1-2-5-12(6-3-1)21-16-13(7-4-9-19-16)17-20-14-8-10-18-11-15(14)22-17/h1-11H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair				3D Structure (crystal)
Large T antigen (JC polyomavirus)	BDBM50533442 (CHEMBL4438480) Show SMILES COc1ccccc1-c1nc2cc(N)ncc2s1 Show InChI InChI=1S/C13H11N3OS/c1-17-10-5-3-2-4-8(10)13-16-9-6-12(14)15-7-11(9)18-13/h2-7H,1H3,(H2,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533450 (CHEMBL4517025) Show SMILES O(c1ccccc1)c1ccccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C15H10N4OS/c1-2-6-11(7-3-1)20-13-9-5-4-8-12(13)14-18-19-10-16-17-15(19)21-14/h1-10H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair				3D Structure (crystal)
Large T antigen (JC polyomavirus)	BDBM50533460 (CHEMBL4537059) Show SMILES COc1ccccc1-c1nc2ccncc2s1 Show InChI InChI=1S/C13H10N2OS/c1-16-11-5-3-2-4-9(11)13-15-10-6-7-14-8-12(10)17-13/h2-8H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533428 (CHEMBL4521406) Show SMILES O(c1ccccc1)c1ccncc1-c1nn2cnnc2s1 Show InChI InChI=1S/C14H9N5OS/c1-2-4-10(5-3-1)20-12-6-7-15-8-11(12)13-18-19-9-16-17-14(19)21-13/h1-9H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533437 (CHEMBL4452337) Show SMILES C(CC1CCOCC1)Oc1ccccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C16H18N4O2S/c1-2-4-14(22-10-7-12-5-8-21-9-6-12)13(3-1)15-19-20-11-17-18-16(20)23-15/h1-4,11-12H,5-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533459 (CHEMBL4474704) Show SMILES C(Oc1ccccc1-c1nn2cnnc2s1)C1CCOCC1 Show InChI InChI=1S/C15H16N4O2S/c1-2-4-13(21-9-11-5-7-20-8-6-11)12(3-1)14-18-19-10-16-17-15(19)22-14/h1-4,10-11H,5-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533440 (CHEMBL4470227) Show SMILES C1Cc2cccc(c2O1)-c1nc2ccncc2s1 Show InChI InChI=1S/C14H10N2OS/c1-2-9-5-7-17-13(9)10(3-1)14-16-11-4-6-15-8-12(11)18-14/h1-4,6,8H,5,7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533455 (CHEMBL4562725) Show SMILES O(c1ccccc1)c1ncccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C14H9N5OS/c1-2-5-10(6-3-1)20-12-11(7-4-8-15-12)13-18-19-9-16-17-14(19)21-13/h1-9H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533427 (CHEMBL4475150) Show SMILES CCOc1ccccc1-c1nc2ccncc2s1 Show InChI InChI=1S/C14H12N2OS/c1-2-17-12-6-4-3-5-10(12)14-16-11-7-8-15-9-13(11)18-14/h3-9H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533454 (CHEMBL4443851) Show SMILES C(CC1CCOCC1)Oc1ccccc1-c1nc2ccncc2s1 Show InChI InChI=1S/C19H20N2O2S/c1-2-4-17(23-12-8-14-6-10-22-11-7-14)15(3-1)19-21-16-5-9-20-13-18(16)24-19/h1-5,9,13-14H,6-8,10-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533439 (CHEMBL4450465) Show SMILES O(c1ccccc1)c1ccccc1-c1nc2ccncc2s1 Show InChI InChI=1S/C18H12N2OS/c1-2-6-13(7-3-1)21-16-9-5-4-8-14(16)18-20-15-10-11-19-12-17(15)22-18/h1-12H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533435 (CHEMBL4459234) Show SMILES C1Cc2cccc(c2O1)-c1nn2cnnc2s1 Show InChI InChI=1S/C11H8N4OS/c1-2-7-4-5-16-9(7)8(3-1)10-14-15-6-12-13-11(15)17-10/h1-3,6H,4-5H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533434 (CHEMBL4442492) Show SMILES C1COc2c(C1)cccc2-c1nn2cnnc2s1 Show InChI InChI=1S/C12H10N4OS/c1-3-8-4-2-6-17-10(8)9(5-1)11-15-16-7-13-14-12(16)18-11/h1,3,5,7H,2,4,6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533430 (CHEMBL4548906) Show SMILES CCOc1ccccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C11H10N4OS/c1-2-16-9-6-4-3-5-8(9)10-14-15-7-12-13-11(15)17-10/h3-7H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533451 (CHEMBL4462771) Show SMILES COc1ccc(-c2nn3cnnc3s2)c(OC)c1 Show InChI InChI=1S/C11H10N4O2S/c1-16-7-3-4-8(9(5-7)17-2)10-14-15-6-12-13-11(15)18-10/h3-6H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533429 (CHEMBL4462427) Show SMILES COc1ccccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C10H8N4OS/c1-15-8-5-3-2-4-7(8)9-13-14-6-11-12-10(14)16-9/h2-6H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533453 (CHEMBL4539070) Show SMILES N#CCCCOc1ccccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C13H11N5OS/c14-7-3-4-8-19-11-6-2-1-5-10(11)12-17-18-9-15-16-13(18)20-12/h1-2,5-6,9H,3-4,8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533447 (CHEMBL4542310) Show SMILES COCCOc1ccccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C12H12N4O2S/c1-17-6-7-18-10-5-3-2-4-9(10)11-15-16-8-13-14-12(16)19-11/h2-5,8H,6-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533441 (CHEMBL4588212) Show SMILES Oc1ccccc1-c1nc2ccncc2s1 Show InChI InChI=1S/C12H8N2OS/c15-10-4-2-1-3-8(10)12-14-9-5-6-13-7-11(9)16-12/h1-7,15H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533438 (CHEMBL4533592) Show SMILES C(CN1CCOCC1)Oc1ccccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C15H17N5O2S/c1-2-4-13(22-10-7-19-5-8-21-9-6-19)12(3-1)14-18-20-11-16-17-15(20)23-14/h1-4,11H,5-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533433 (CHEMBL4552648) Show SMILES COc1cccc(-c2nn3cnnc3s2)c1OC Show InChI InChI=1S/C11H10N4O2S/c1-16-8-5-3-4-7(9(8)17-2)10-14-15-6-12-13-11(15)18-10/h3-6H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533426 (CHEMBL4436602) Show SMILES COc1cccc(OC)c1-c1nn2cnnc2s1 Show InChI InChI=1S/C11H10N4O2S/c1-16-7-4-3-5-8(17-2)9(7)10-14-15-6-12-13-11(15)18-10/h3-6H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533458 (CHEMBL4584998) Show SMILES C1CC1c1ccccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C12H10N4S/c1-2-4-10(9(3-1)8-5-6-8)11-15-16-7-13-14-12(16)17-11/h1-4,7-8H,5-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533457 (CHEMBL4574591) Show SMILES O(c1ccccc1)c1ncncc1-c1nn2cnnc2s1 Show InChI InChI=1S/C13H8N6OS/c1-2-4-9(5-3-1)20-11-10(6-14-7-15-11)12-18-19-8-16-17-13(19)21-12/h1-8H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533456 (CHEMBL4556570) Show SMILES Nc1ccccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C9H7N5S/c10-7-4-2-1-3-6(7)8-13-14-5-11-12-9(14)15-8/h1-5H,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533452 (CHEMBL4461656) Show SMILES Oc1ccccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C9H6N4OS/c14-7-4-2-1-3-6(7)8-12-13-5-10-11-9(13)15-8/h1-5,14H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533436 (CHEMBL4549260) Show SMILES COc1ccccc1Cc1nn2cnnc2s1 Show InChI InChI=1S/C11H10N4OS/c1-16-9-5-3-2-4-8(9)6-10-14-15-7-12-13-11(15)17-10/h2-5,7H,6H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533448 (CHEMBL4580158) Show SMILES COc1ccccc1-c1nc2ccnc(N)c2s1 Show InChI InChI=1S/C13H11N3OS/c1-17-10-5-3-2-4-8(10)13-16-9-6-7-15-12(14)11(9)18-13/h2-7H,1H3,(H2,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533431 (CHEMBL4538961) Show SMILES Cc1ccccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C10H8N4S/c1-7-4-2-3-5-8(7)9-13-14-6-11-12-10(14)15-9/h2-6H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533432 (CHEMBL4465365) Show SMILES CN(C)c1ccccc1-c1nn2cnnc2s1 Show InChI InChI=1S/C11H11N5S/c1-15(2)9-6-4-3-5-8(9)10-14-16-7-12-13-11(16)17-10/h3-7H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533443 (CHEMBL4562789) Show SMILES CNc1cc2nc(sc2cn1)-c1ccccc1OC Show InChI InChI=1S/C14H13N3OS/c1-15-13-7-10-12(8-16-13)19-14(17-10)9-5-3-4-6-11(9)18-2/h3-8H,1-2H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair
Large T antigen (JC polyomavirus)	BDBM50533449 (CHEMBL4573145) Show SMILES CCOc1ccccc1-c1nc2cnccc2s1 Show InChI InChI=1S/C14H12N2OS/c1-2-17-12-6-4-3-5-10(12)14-16-11-9-15-8-7-13(11)18-14/h3-9H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of helicase activity of JC polyomavirus LTAg (E264 to D628 residues) expressed in Escherichia coli using Cy5/BHQ3 dsDNA pre-incubated for ...				J Med Chem 59: 7138-51 (2016) Article DOI: 10.1021/acs.jmedchem.6b00486 BindingDB Entry DOI: 10.7270/Q22Z1900
					More data for this Ligand-Target Pair