Compile Data Set for Download or QSAR

Found 7 hits of ic50 for UniProtKB: P19493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor 4 (Rattus norvegicus)	BDBM50316374 (CHEMBL1096289 | N-(4-hydroxyphenylpropanyl)-spermi...) Show SMILES NCCCNCCCCNCCCNC(=O)CCc1ccccc1 Show InChI InChI=1S/C19H34N4O/c20-12-6-15-21-13-4-5-14-22-16-7-17-23-19(24)11-10-18-8-2-1-3-9-18/h1-3,8-9,21-22H,4-7,10-17,20H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat recombinant GluA4 receptor expressed in Xenopus oocytes assessed as inhibition of 300 uM kainate-induced current				Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Rattus norvegicus)	BDBM50158554 (CHEMBL224688 | {2-[3-(3-bromophenyl)ureido]-4-chlo...) Show SMILES OC(=O)Cc1ccc(Cl)cc1NC(=O)Nc1cccc(Br)c1 Show InChI InChI=1S/C15H12BrClN2O3/c16-10-2-1-3-12(7-10)18-15(22)19-13-8-11(17)5-4-9(13)6-14(20)21/h1-5,7-8H,6H2,(H,20,21)(H2,18,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat homomeric recombinant GluR4 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Rattus norvegicus)	BDBM50158555 (1-[5-chloro-2-(5-oxo-4,5-dihydro-[1,2,4]oxadiazol-...) Show SMILES Clc1ccc(-c2nc(=O)o[nH]2)c(NC(=O)Nc2cccc(Br)c2)c1 Show InChI InChI=1S/C15H10BrClN4O3/c16-8-2-1-3-10(6-8)18-14(22)19-12-7-9(17)4-5-11(12)13-20-15(23)24-21-13/h1-7H,(H2,18,19,22)(H,20,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat homomeric recombinant GluR4 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Rattus norvegicus)	BDBM50137125 (2-(3-(3-bromophenyl)ureido)-4-chlorobenzoic acid |...) Show SMILES OC(=O)c1ccc(Cl)cc1NC(=O)Nc1cccc(Br)c1 Show InChI InChI=1S/C14H10BrClN2O3/c15-8-2-1-3-10(6-8)17-14(21)18-12-7-9(16)4-5-11(12)13(19)20/h1-7H,(H,19,20)(H2,17,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat homomeric recombinant GluR4 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Rattus norvegicus)	BDBM50158561 (2-[3-(3-bromophenyl)ureido]-4-chlorobenzenesulfoni...) Show SMILES OS(=O)(=O)c1ccc(Cl)cc1NC(=O)Nc1cccc(Br)c1 Show InChI InChI=1S/C13H10BrClN2O4S/c14-8-2-1-3-10(6-8)16-13(18)17-11-7-9(15)4-5-12(11)22(19,20)21/h1-7H,(H2,16,17,18)(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat homomeric recombinant GluR4 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Rattus norvegicus)	BDBM50137124 (4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...) Show SMILES OC(=O)c1ccc(Cl)cc1NC(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C18H13ClN2O3/c19-13-6-8-15(17(22)23)16(10-13)21-18(24)20-14-7-5-11-3-1-2-4-12(11)9-14/h1-10H,(H,22,23)(H2,20,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat homomeric recombinant GluR4 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Rattus norvegicus)	BDBM50158556 (1-(3-bromophenyl)-3-[5-chloro-2-(1H-tetrazol-5-yl-...) Show SMILES Clc1ccc(-c2nnn[nH]2)c(NC(=O)Nc2cccc(Br)c2)c1 Show InChI InChI=1S/C14H10BrClN6O/c15-8-2-1-3-10(6-8)17-14(23)18-12-7-9(16)4-5-11(12)13-19-21-22-20-13/h1-7H,(H2,17,18,23)(H,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat homomeric recombinant GluR4 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...				J Med Chem 47: 6948-57 (2004) Article DOI: 10.1021/jm030638w BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
					More data for this Ligand-Target Pair