Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50002471 (5-Amino-2-{4-[(2-amino-4-oxo-2,3,4,4a,5,6,7,8-octa...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description In vitro inhibition of mouse liver Folyl-polyglutamate synthase | J Med Chem 35: 1578-88 (1992) BindingDB Entry DOI: 10.7270/Q2028S6J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50006906 (2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-am...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Binding affinity of the compound towards Folyl polyglutamate synthetase (FPGS) | J Med Chem 35: 2626-30 (1992) BindingDB Entry DOI: 10.7270/Q2DV1HVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50011885 (5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-am...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liver | J Med Chem 29: 655-60 (1986) BindingDB Entry DOI: 10.7270/Q2RR1ZTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50020107 (5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-am...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibitory constant against purified Folyl-polyglutamate synthase obtained from mouse | J Med Chem 31: 1338-44 (1988) BindingDB Entry DOI: 10.7270/Q22J6CFD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50006907 (2-{4-[(4-Oxo-3,4-dihydro-quinazolin-6-ylmethyl)-am...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Binding affinity of the compound towards Folyl polyglutamate synthetase (FPGS) | J Med Chem 35: 2626-30 (1992) BindingDB Entry DOI: 10.7270/Q2DV1HVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50006905 (2-{4-[(4-Oxo-3,4-dihydro-benzo[d][1,2,3]triazin-6-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Binding affinity of the compound towards Folyl polyglutamate synthetase (FPGS) | J Med Chem 35: 2626-30 (1992) BindingDB Entry DOI: 10.7270/Q2DV1HVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50005868 (2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-pyrido[...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description In vitro inhibition of mouse liver Folyl-polyglutamate synthase | J Med Chem 35: 1578-88 (1992) BindingDB Entry DOI: 10.7270/Q2028S6J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50020102 (5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibitory constant against purified Folyl-polyglutamate synthase obtained from rat | J Med Chem 31: 1338-44 (1988) BindingDB Entry DOI: 10.7270/Q22J6CFD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50005859 (5-Amino-2-{4-[(2,4-diamino-pyrido[3,2-d]pyrimidin-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description In vitro inhibition of mouse liver Folyl-polyglutamate synthase | J Med Chem 35: 1578-88 (1992) BindingDB Entry DOI: 10.7270/Q2028S6J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50020101 (2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibitory constant against purified Folyl-polyglutamate synthase obtained from mouse | J Med Chem 31: 1338-44 (1988) BindingDB Entry DOI: 10.7270/Q22J6CFD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50005867 (2-{4-[(2-Amino-4-oxo-3,4-dihydro-pyrido[2,3-d]pyri...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description In vitro inhibition of mouse liver Folyl-polyglutamate synthase | J Med Chem 35: 1578-88 (1992) BindingDB Entry DOI: 10.7270/Q2028S6J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | AMINOPTE...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars | PubMed | 1.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liver | J Med Chem 29: 655-60 (1986) BindingDB Entry DOI: 10.7270/Q2RR1ZTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50020102 (5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibitory constant against purified Folyl-polyglutamate synthase obtained from mouse liver | J Med Chem 31: 1338-44 (1988) BindingDB Entry DOI: 10.7270/Q22J6CFD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50011886 (5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liver | J Med Chem 29: 655-60 (1986) BindingDB Entry DOI: 10.7270/Q2RR1ZTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50005865 (2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-pyrido[...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description In vitro inhibition of mouse liver Folyl-polyglutamate synthase | J Med Chem 35: 1578-88 (1992) BindingDB Entry DOI: 10.7270/Q2028S6J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50005860 (2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-pyrido[...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.15E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description In vitro inhibition of mouse liver Folyl-polyglutamate synthase | J Med Chem 35: 1578-88 (1992) BindingDB Entry DOI: 10.7270/Q2028S6J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 1.66E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liver | J Med Chem 29: 655-60 (1986) BindingDB Entry DOI: 10.7270/Q2RR1ZTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50020099 (2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibitory constant against purified Folyl-polyglutamate synthase from mouse liver | J Med Chem 31: 1338-44 (1988) BindingDB Entry DOI: 10.7270/Q22J6CFD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50005863 (2-{4-[(2-Amino-4-oxo-3,4-dihydro-pyrido[2,3-d]pyri...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 5.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description In vitro inhibition of mouse liver Folyl-polyglutamate synthase | J Med Chem 35: 1578-88 (1992) BindingDB Entry DOI: 10.7270/Q2028S6J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpolyglutamate synthase, mitochondrial (Mus musculus) | BDBM50005866 (2-{4-[(2-Amino-4-oxo-3,4-dihydro-pyrido[2,3-d]pyri...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description In vitro inhibition of mouse liver Folyl-polyglutamate synthase | J Med Chem 35: 1578-88 (1992) BindingDB Entry DOI: 10.7270/Q2028S6J | |||||||||||
More data for this Ligand-Target Pair |