Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50069111 ((2S,4S)-2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly Curated by ChEMBL | Assay Description Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparations | Bioorg Med Chem Lett 8: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2T152SF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50288204 ((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested in vitro for binding affinity against Ionotropic glutamate receptor kainate using [3H]-kainate as the radioligand. | Bioorg Med Chem Lett 6: 2559-2564 (1996) Article DOI: 10.1016/0960-894X(96)00464-7 BindingDB Entry DOI: 10.7270/Q2HX1CN1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50069120 ((2S,4S)-2-Amino-4-(3,3-diphenyl-propyl)-pentanedio...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly Curated by ChEMBL | Assay Description Binding affinity against Ionotropic glutamate receptor using ACPD sensitive [3H]- glutamate displacement from rat forebrain preparations | Bioorg Med Chem Lett 8: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2T152SF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50069118 ((2S,4S)-2-Amino-4-(3-phenyl-propyl)-pentanedioic a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly Curated by ChEMBL | Assay Description Binding affinity against Ionotropic glutamate receptor using ACPD sensitive [3H]- glutamate displacement from rat forebrain preparations | Bioorg Med Chem Lett 8: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2T152SF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50069118 ((2S,4S)-2-Amino-4-(3-phenyl-propyl)-pentanedioic a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly Curated by ChEMBL | Assay Description Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparations | Bioorg Med Chem Lett 8: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2T152SF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50069120 ((2S,4S)-2-Amino-4-(3,3-diphenyl-propyl)-pentanedio...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly Curated by ChEMBL | Assay Description Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparations | Bioorg Med Chem Lett 8: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2T152SF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined against KA receptor, using radioligand [3H]- KA | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50069111 ((2S,4S)-2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly Curated by ChEMBL | Assay Description Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparations | Bioorg Med Chem Lett 8: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2T152SF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50017244 ((R,S)-2-amino-3-(4-bromo-3-hydroxy-5-isoxazolyl)pr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined against KA receptor, using radioligand [3H]- KA | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50128264 ((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined against KA receptor,using radioligand [3H]- KA | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50049748 ((2S,4S)-2-Amino-4-(4,4-diphenyl-butyl)-pentanedioi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.47E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly Curated by ChEMBL | Assay Description Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparations | Bioorg Med Chem Lett 8: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2T152SF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50049748 ((2S,4S)-2-Amino-4-(4,4-diphenyl-butyl)-pentanedioi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.47E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly Curated by ChEMBL | Assay Description Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparations | Bioorg Med Chem Lett 8: 765-70 (1999) BindingDB Entry DOI: 10.7270/Q2T152SF | |||||||||||
More data for this Ligand-Target Pair |