Compile Data Set for Download or QSAR

Found 119 hits of ec50 for UniProtKB: P04608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM29589 (Faridak | LBH-589 | LBH-589B | Panobinostat | US10...) Show SMILES Cc1[nH]c2ccccc2c1CCNCc1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in J-Lat 10.6 cells harboring LTR driven GFP reporter co-expressing CMV driven RFP reporter assessed as...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50048864 (CHEMBL3310505) Show SMILES [H][C@@]12CC(=O)N[C@H](C(C)C)C(=O)N[C@]([H])(CSSCC\C=C\1)C(=O)N\C(=C/C)C(=O)N[C@@H](C(C)C)C(=O)O2 |r,t:20| Show InChI InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17+,19+,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in J-Lat 10.6 cells harboring LTR driven GFP reporter co-expressing CMV driven RFP reporter assessed as...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524891 (CHEMBL4526214) Show SMILES FC(F)(F)c1cnc(NC(=O)CCCOc2cccc(c2)C#N)s1 Show InChI InChI=1S/C15H12F3N3O2S/c16-15(17,18)12-9-20-14(24-12)21-13(22)5-2-6-23-11-4-1-3-10(7-11)8-19/h1,3-4,7,9H,2,5-6H2,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524887 (CHEMBL4446565) Show SMILES Clc1cccc(OCCCC(=O)Nc2ncc(s2)C#N)c1 Show InChI InChI=1S/C14H12ClN3O2S/c15-10-3-1-4-11(7-10)20-6-2-5-13(19)18-14-17-9-12(8-16)21-14/h1,3-4,7,9H,2,5-6H2,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50476285 (CHEMBL609729) Show SMILES CC(Cl)c1ccc(NCCCN)c(c1)[N+]([O-])=O Show InChI InChI=1S/C11H16ClN3O2/c1-8(12)9-3-4-10(14-6-2-5-13)11(7-9)15(16)17/h3-4,7-8,14H,2,5-6,13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Tat-mediated transcription of viral promoter in 293 T cells transfected with HIV1 tat by luciferase reporter gene assay				J Med Chem 50: 2285-8 (2007) Article DOI: 10.1021/jm070014g BindingDB Entry DOI: 10.7270/Q2WW7MG1
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524928 (CHEMBL4457218) Show SMILES COc1ccccc1OCCCC(=O)Nc1ncc(C)s1 Show InChI InChI=1S/C15H18N2O3S/c1-11-10-16-15(21-11)17-14(18)8-5-9-20-13-7-4-3-6-12(13)19-2/h3-4,6-7,10H,5,8-9H2,1-2H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524948 (CHEMBL4450433) Show SMILES Clc1cnc(NC(=O)CCCOc2cccc(Cl)c2)s1 Show InChI InChI=1S/C13H12Cl2N2O2S/c14-9-3-1-4-10(7-9)19-6-2-5-12(18)17-13-16-8-11(15)20-13/h1,3-4,7-8H,2,5-6H2,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524932 (CHEMBL4439301) Show SMILES Cc1cnc(NC(=O)CCCOc2cccc(Cl)c2)s1 Show InChI InChI=1S/C14H15ClN2O2S/c1-10-9-16-14(20-10)17-13(18)6-3-7-19-12-5-2-4-11(15)8-12/h2,4-5,8-9H,3,6-7H2,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524947 (CHEMBL4531178) Show SMILES Clc1cnc(NC(=O)CCCOc2cccc(c2)C#N)s1 Show InChI InChI=1S/C14H12ClN3O2S/c15-12-9-17-14(21-12)18-13(19)5-2-6-20-11-4-1-3-10(7-11)8-16/h1,3-4,7,9H,2,5-6H2,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524929 (CHEMBL4582511) Show SMILES Cc1cnc(NC(=O)CCCOc2cccc(c2)C#N)s1 Show InChI InChI=1S/C15H15N3O2S/c1-11-10-17-15(21-11)18-14(19)6-3-7-20-13-5-2-4-12(8-13)9-16/h2,4-5,8,10H,3,6-7H2,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524940 (CHEMBL4437258) Show SMILES Cc1cnc(NC(=O)CCCOc2cccc(C)c2)s1 Show InChI InChI=1S/C15H18N2O2S/c1-11-5-3-6-13(9-11)19-8-4-7-14(18)17-15-16-10-12(2)20-15/h3,5-6,9-10H,4,7-8H2,1-2H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524889 (CHEMBL4552693) Show SMILES Cc1cc(OCCCC(=O)Nc2ncc(Cl)s2)ccc1Cl Show InChI InChI=1S/C14H14Cl2N2O2S/c1-9-7-10(4-5-11(9)15)20-6-2-3-13(19)18-14-17-8-12(16)21-14/h4-5,7-8H,2-3,6H2,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524888 (CHEMBL4540359) Show SMILES FC(F)(F)c1cnc(NC(=O)CCCOc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C15H12F6N2O2S/c16-14(17,18)9-3-1-4-10(7-9)25-6-2-5-12(24)23-13-22-8-11(26-13)15(19,20)21/h1,3-4,7-8H,2,5-6H2,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in J-Lat 10.6 cells harboring LTR driven GFP reporter co-expressing CMV driven RFP reporter assessed as...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524918 (CHEMBL4463956) Show SMILES Cc1cnc(NC(=O)CCCOc2cc(C)cc(C)c2)s1 Show InChI InChI=1S/C16H20N2O2S/c1-11-7-12(2)9-14(8-11)20-6-4-5-15(19)18-16-17-10-13(3)21-16/h7-10H,4-6H2,1-3H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524934 (CHEMBL4465487) Show SMILES Clc1cnc(NC(=O)CCCOc2ccc(Cl)c(Cl)c2)s1 Show InChI InChI=1S/C13H11Cl3N2O2S/c14-9-4-3-8(6-10(9)15)20-5-1-2-12(19)18-13-17-7-11(16)21-13/h3-4,6-7H,1-2,5H2,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524930 (CHEMBL4555472) Show SMILES Cc1cnc(NC(=O)CCCOc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C15H15F3N2O2S/c1-10-9-19-14(23-10)20-13(21)6-3-7-22-12-5-2-4-11(8-12)15(16,17)18/h2,4-5,8-9H,3,6-7H2,1H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524935 (CHEMBL4450555) Show SMILES Cc1ccc(OCCCC(=O)Nc2ncc(Cl)s2)cc1Cl Show InChI InChI=1S/C14H14Cl2N2O2S/c1-9-4-5-10(7-11(9)15)20-6-2-3-13(19)18-14-17-8-12(16)21-14/h4-5,7-8H,2-3,6H2,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524945 (CHEMBL4464874) Show SMILES Cc1cnc(NC(=O)CCCOc2cc(Cl)ccn2)s1 Show InChI InChI=1S/C13H14ClN3O2S/c1-9-8-16-13(20-9)17-11(18)3-2-6-19-12-7-10(14)4-5-15-12/h4-5,7-8H,2-3,6H2,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524899 (CHEMBL4458012) Show SMILES Cc1cnc(NC(=O)NCCOc2ccc(Cl)c(C)c2)s1 Show InChI InChI=1S/C14H16ClN3O2S/c1-9-7-11(3-4-12(9)15)20-6-5-16-13(19)18-14-17-8-10(2)21-14/h3-4,7-8H,5-6H2,1-2H3,(H2,16,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524949 (CHEMBL4445805) Show SMILES Cc1cnc(NC(=O)CCCOc2cncc(Cl)c2)s1 Show InChI InChI=1S/C13H14ClN3O2S/c1-9-6-16-13(20-9)17-12(18)3-2-4-19-11-5-10(14)7-15-8-11/h5-8H,2-4H2,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524917 (CHEMBL4575028) Show SMILES FC(F)(F)c1cnc(NC(=O)CCCOc2ccccc2)s1 Show InChI InChI=1S/C14H13F3N2O2S/c15-14(16,17)11-9-18-13(22-11)19-12(20)7-4-8-21-10-5-2-1-3-6-10/h1-3,5-6,9H,4,7-8H2,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524892 (CHEMBL4576878) Show SMILES FC(F)(F)c1cnc(NC(=O)CCCOc2cccc(Cl)c2)s1 Show InChI InChI=1S/C14H12ClF3N2O2S/c15-9-3-1-4-10(7-9)22-6-2-5-12(21)20-13-19-8-11(23-13)14(16,17)18/h1,3-4,7-8H,2,5-6H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524890 (CHEMBL4460170) Show SMILES FC(F)(F)c1cccc(OCCCC(=O)Nc2ncc(s2)C#N)c1 Show InChI InChI=1S/C15H12F3N3O2S/c16-15(17,18)10-3-1-4-11(7-10)23-6-2-5-13(22)21-14-20-9-12(8-19)24-14/h1,3-4,7,9H,2,5-6H2,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524887 (CHEMBL4446565) Show SMILES Clc1cccc(OCCCC(=O)Nc2ncc(s2)C#N)c1 Show InChI InChI=1S/C14H12ClN3O2S/c15-10-3-1-4-11(7-10)20-6-2-5-13(19)18-14-17-9-12(8-16)21-14/h1,3-4,7,9H,2,5-6H2,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in J-Lat 10.6 cells harboring LTR driven GFP reporter co-expressing CMV driven RFP reporter assessed as...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524875 (CHEMBL4439569) Show SMILES Cc1cnc(NC(=O)CCCOc2cc(C)cc(Cl)c2)s1 Show InChI InChI=1S/C15H17ClN2O2S/c1-10-6-12(16)8-13(7-10)20-5-3-4-14(19)18-15-17-9-11(2)21-15/h6-9H,3-5H2,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524882 (CHEMBL4465202) Show SMILES Cc1cc(OCCCC(=O)Nc2ncc(Br)s2)ccc1Cl Show InChI InChI=1S/C14H14BrClN2O2S/c1-9-7-10(4-5-11(9)16)20-6-2-3-13(19)18-14-17-8-12(15)21-14/h4-5,7-8H,2-3,6H2,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524921 (CHEMBL4463494) Show SMILES Cc1cnc(NC(=O)CCCOc2ccc(Cl)c(c2)C(F)(F)F)s1 Show InChI InChI=1S/C15H14ClF3N2O2S/c1-9-8-20-14(24-9)21-13(22)3-2-6-23-10-4-5-12(16)11(7-10)15(17,18)19/h4-5,7-8H,2-3,6H2,1H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524886 (CHEMBL4467303) Show SMILES Brc1cnc(NC(=O)CCCOc2ccccc2)s1 Show InChI InChI=1S/C13H13BrN2O2S/c14-11-9-15-13(19-11)16-12(17)7-4-8-18-10-5-2-1-3-6-10/h1-3,5-6,9H,4,7-8H2,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524879 (CHEMBL4531268) Show SMILES O=C(CCCOc1cccc(c1)C#N)Nc1ncc(s1)C#N Show InChI InChI=1S/C15H12N4O2S/c16-8-11-3-1-4-12(7-11)21-6-2-5-14(20)19-15-18-10-13(9-17)22-15/h1,3-4,7,10H,2,5-6H2,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524936 (CHEMBL4437444) Show SMILES Cc1cc(OCCCC(=O)Nc2ncc(s2)C(F)(F)F)ccc1Cl Show InChI InChI=1S/C15H14ClF3N2O2S/c1-9-7-10(4-5-11(9)16)23-6-2-3-13(22)21-14-20-8-12(24-14)15(17,18)19/h4-5,7-8H,2-3,6H2,1H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524946 (CHEMBL4435131) Show SMILES FC(F)(F)c1cccc(OCCCC(=O)Nc2ncc(Cl)s2)c1 Show InChI InChI=1S/C14H12ClF3N2O2S/c15-11-8-19-13(23-11)20-12(21)5-2-6-22-10-4-1-3-9(7-10)14(16,17)18/h1,3-4,7-8H,2,5-6H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524969 (CHEMBL4547664) Show SMILES Cc1cnc(NC(=O)CCCOc2cccc(Cl)n2)s1 Show InChI InChI=1S/C13H14ClN3O2S/c1-9-8-15-13(20-9)17-11(18)5-3-7-19-12-6-2-4-10(14)16-12/h2,4,6,8H,3,5,7H2,1H3,(H,15,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524960 (CHEMBL4522266) Show SMILES Cc1cnc(NC(=O)CCCOc2ccc(C)c(Cl)c2)s1 Show InChI InChI=1S/C15H17ClN2O2S/c1-10-5-6-12(8-13(10)16)20-7-3-4-14(19)18-15-17-9-11(2)21-15/h5-6,8-9H,3-4,7H2,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524957 (CHEMBL4445251) Show SMILES CCc1cnc(NC(=O)CCCOc2ccccc2)s1 Show InChI InChI=1S/C15H18N2O2S/c1-2-13-11-16-15(20-13)17-14(18)9-6-10-19-12-7-4-3-5-8-12/h3-5,7-8,11H,2,6,9-10H2,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524958 (CHEMBL4559333) Show SMILES Clc1cnc(NC(=O)CCCOc2ccccc2)s1 Show InChI InChI=1S/C13H13ClN2O2S/c14-11-9-15-13(19-11)16-12(17)7-4-8-18-10-5-2-1-3-6-10/h1-3,5-6,9H,4,7-8H2,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524951 (CHEMBL4532989) Show SMILES CN(CCCC(=O)Nc1ncc(C)s1)c1ccccc1 Show InChI InChI=1S/C15H19N3OS/c1-12-11-16-15(20-12)17-14(19)9-6-10-18(2)13-7-4-3-5-8-13/h3-5,7-8,11H,6,9-10H2,1-2H3,(H,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524916 (CHEMBL4439266) Show SMILES CC(C)c1cnc(NC(=O)CCCOc2ccccc2)s1 Show InChI InChI=1S/C16H20N2O2S/c1-12(2)14-11-17-16(21-14)18-15(19)9-6-10-20-13-7-4-3-5-8-13/h3-5,7-8,11-12H,6,9-10H2,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524924 (CHEMBL4528111) Show SMILES Cc1cnc(NC(=O)CCCOc2cccc(CO)c2)s1 Show InChI InChI=1S/C15H18N2O3S/c1-11-9-16-15(21-11)17-14(19)6-3-7-20-13-5-2-4-12(8-13)10-18/h2,4-5,8-9,18H,3,6-7,10H2,1H3,(H,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524884 (CHEMBL1386792) Show SMILES Clc1ccc(NC(=O)CCCOc2ccccc2)nc1 Show InChI InChI=1S/C15H15ClN2O2/c16-12-8-9-14(17-11-12)18-15(19)7-4-10-20-13-5-2-1-3-6-13/h1-3,5-6,8-9,11H,4,7,10H2,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524905 (CHEMBL4546726) Show SMILES Brc1ccc(NC(=O)CCCOc2ccccc2)nc1 Show InChI InChI=1S/C15H15BrN2O2/c16-12-8-9-14(17-11-12)18-15(19)7-4-10-20-13-5-2-1-3-6-13/h1-3,5-6,8-9,11H,4,7,10H2,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50210164 (CHEMBL2132936) Show SMILES Cc1nnc2C(CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in J-Lat 10.6 cells harboring LTR driven GFP reporter co-expressing CMV driven RFP reporter assessed as...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524938 (CHEMBL4441342) Show SMILES Cc1cnc(NC(=O)CCCOc2ccc(Cl)c(Cl)c2)s1 Show InChI InChI=1S/C14H14Cl2N2O2S/c1-9-8-17-14(21-9)18-13(19)3-2-6-20-10-4-5-11(15)12(16)7-10/h4-5,7-8H,2-3,6H2,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524888 (CHEMBL4540359) Show SMILES FC(F)(F)c1cnc(NC(=O)CCCOc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C15H12F6N2O2S/c16-14(17,18)9-3-1-4-10(7-9)25-6-2-5-12(24)23-13-22-8-11(26-13)15(19,20)21/h1,3-4,7-8H,2,5-6H2,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in J-Lat 10.6 cells harboring LTR driven GFP reporter co-expressing CMV driven RFP reporter assessed as...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50398244 (CHEMBL609728) Show SMILES Cc1ccc(NCCCN)c(c1)[N+]([O-])=O Show InChI InChI=1S/C10H15N3O2/c1-8-3-4-9(12-6-2-5-11)10(7-8)13(14)15/h3-4,7,12H,2,5-6,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Tat-mediated transcription of viral promoter in 293 T cells transfected with HIV1 tat by luciferase reporter gene assay				J Med Chem 50: 2285-8 (2007) Article DOI: 10.1021/jm070014g BindingDB Entry DOI: 10.7270/Q2WW7MG1
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524894 (CHEMBL4538496) Show SMILES Cc1cnc(NC(=O)CCCOc2cncc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C14H14F3N3O2S/c1-9-6-19-13(23-9)20-12(21)3-2-4-22-11-5-10(7-18-8-11)14(15,16)17/h5-8H,2-4H2,1H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524874 (CHEMBL4549436) Show SMILES O=C(CCCOc1ccccc1)Nc1ncc(s1)C#N Show InChI InChI=1S/C14H13N3O2S/c15-9-12-10-16-14(20-12)17-13(18)7-4-8-19-11-5-2-1-3-6-11/h1-3,5-6,10H,4,7-8H2,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524937 (CHEMBL4585376) Show SMILES Cc1cnc(NC(=O)CCCOc2cc(cc(c2)C#N)C#N)s1 Show InChI InChI=1S/C16H14N4O2S/c1-11-10-19-16(23-11)20-15(21)3-2-4-22-14-6-12(8-17)5-13(7-14)9-18/h5-7,10H,2-4H2,1H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524890 (CHEMBL4460170) Show SMILES FC(F)(F)c1cccc(OCCCC(=O)Nc2ncc(s2)C#N)c1 Show InChI InChI=1S/C15H12F3N3O2S/c16-15(17,18)10-3-1-4-11(7-10)23-6-2-5-13(22)21-14-20-9-12(8-19)24-14/h1,3-4,7,9H,2,5-6H2,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in J-Lat 10.6 cells harboring LTR driven GFP reporter co-expressing CMV driven RFP reporter assessed as...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair
Protein Tat (Human immunodeficiency virus type 1 (isolate HXB2 ...)	BDBM50524901 (CHEMBL4464671) Show SMILES Cc1cnc(NC(=O)CCCCc2ccccc2)s1 Show InChI InChI=1S/C15H18N2OS/c1-12-11-16-15(19-12)17-14(18)10-6-5-9-13-7-3-2-4-8-13/h2-4,7-8,11H,5-6,9-10H2,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute for Medical Research Curated by ChEMBL					Assay Description Activation of Tat-mediated HIV1 transcription in HEK293- FlpIn-FM cells harboring LTR driven CBR reporter co-expressing CMV driven CBG reporter asses...				J Med Chem 62: 5148-5175 (2019) Article DOI: 10.1021/acs.jmedchem.9b00462 BindingDB Entry DOI: 10.7270/Q2FX7DW7
					More data for this Ligand-Target Pair

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