Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae) | BDBM27216 ((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae cdc28 | Science 281: 533-538 (1998) BindingDB Entry DOI: 10.7270/Q28G8MMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae) | BDBM7478 (2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae cdc28 | Science 281: 533-538 (1998) BindingDB Entry DOI: 10.7270/Q28G8MMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae) | BDBM7377 (4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol | ...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS USR-3151 Curated by ChEMBL | Assay Description Inhibition of hemagglutinin-tagged Saccharomyces cerevisiae MNY629 Cdc28/Clb2 | Bioorg Med Chem 17: 5572-82 (2009) Article DOI: 10.1016/j.bmc.2009.06.024 BindingDB Entry DOI: 10.7270/Q22J6BWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae) | BDBM50113707 (2,6,9-Trisubstitute purine, 2 | 2-(2-hydroxyethyla...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of yeast W303 cdc28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation counting | Science 281: 533-538 (1998) BindingDB Entry DOI: 10.7270/Q28G8MMG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae) | BDBM50129555 ((1R,2R)-2-((4E,6Z)-(2S,8R,9S,11R,13S,15S,16S)-7-cy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boston University Curated by ChEMBL | Assay Description Inhibition of cyclin-dependent kinase activity of Cdc28p/CDK2p in S. cerevisiae | Bioorg Med Chem Lett 13: 2235-7 (2003) BindingDB Entry DOI: 10.7270/Q20Z72N8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae) | BDBM50295351 (CHEMBL560452 | N-methyl-aloisine A) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS USR-3151 Curated by ChEMBL | Assay Description Inhibition of hemagglutinin-tagged Saccharomyces cerevisiae MNY629 Cdc28/Clb2 | Bioorg Med Chem 17: 5572-82 (2009) Article DOI: 10.1016/j.bmc.2009.06.024 BindingDB Entry DOI: 10.7270/Q22J6BWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae) | BDBM50267719 (2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of yeast W303 cdc28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation counting | Science 281: 533-538 (1998) BindingDB Entry DOI: 10.7270/Q28G8MMG | |||||||||||
More data for this Ligand-Target Pair |