Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137236 (5-Acetylamino-2-{[2-(3-fluoro-4-trifluoromethyl-ph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137238 (2-{[2-(3-Fluoro-4-trifluoromethyl-phenyl)-5-oxo-ox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50178647 (5-chloro-2-{[(9-oxo-9H-fluoren-4-yl)carbonyl]amino...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibitory activity against Bacillus subtilis AcpS by HTRF assay | J Med Chem 48: 7960-9 (2005) Article DOI: 10.1021/jm050523n BindingDB Entry DOI: 10.7270/Q2W66KBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137242 (5-Methyl-2-{[5-oxo-2-(4-trifluoromethyl-phenyl)-ox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137227 (5-Chloro-2-{[2-(3-fluoro-4-trifluoromethyl-phenyl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137229 (2-{[2-(4-Chloro-phenyl)-5-oxo-oxazol-(4E)-ylidenem...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50178649 (5-chloro-2-[3-(4-chlorophenyl)-2-methylsulfanyl-pr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibitory activity against Bacillus subtilis AcpS by HTRF assay | J Med Chem 48: 7960-9 (2005) Article DOI: 10.1021/jm050523n BindingDB Entry DOI: 10.7270/Q2W66KBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137234 (5-Bromo-2-{[2-(3-fluoro-4-trifluoromethyl-phenyl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137233 (5-Fluoro-2-{[5-oxo-2-(4-trifluoromethyl-phenyl)-ox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137235 (5-Bromo-4-chloro-2-{[5-oxo-2-(4-trifluoromethyl-ph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137239 (2-{[2-(4-Chloro-phenyl)-5-oxo-oxazol-(4E)-ylidenem...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50178646 (5-chloro-2-[(2-methyl-3-phenylpropanoyl)amino]benz...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibitory activity against Bacillus subtilis AcpS by HTRF assay | J Med Chem 48: 7960-9 (2005) Article DOI: 10.1021/jm050523n BindingDB Entry DOI: 10.7270/Q2W66KBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137230 (5-Bromo-2-{[2-(4-chloro-phenyl)-5-oxo-oxazol-(4E)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137231 (5-Methyl-2-{[5-oxo-2-(3-trifluoromethoxy-phenyl)-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against acyl carrier protein synthase (AcpS) in Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM25902 (4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibitory activity against Bacillus subtilis AcpS by HTRF assay | J Med Chem 48: 7960-9 (2005) Article DOI: 10.1021/jm050523n BindingDB Entry DOI: 10.7270/Q2W66KBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137237 (5-Bromo-2-{[5-oxo-2-(3-trifluoromethoxy-phenyl)-ox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137240 (2-{[2-(4-Chloro-phenyl)-5-oxo-oxazol-(4E)-ylidenem...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137232 (5-Chloro-2-{[5-oxo-2-(3-trifluoromethoxy-phenyl)-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137228 (5-Fluoro-2-{[2-(4-methoxy-phenyl)-5-oxo-oxazol-(4E...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137241 (5-Bromo-4-chloro-2-{[2-(4-chloro-phenyl)-5-oxo-oxa...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50137243 (2-{[5-Oxo-2-phenyl-oxazol-(4E)-ylidenemethyl]-amin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibitory activity against Holo-[acyl-carrier-protein] synthase was determined using Bacillus subtilis GST-Acp-HTRFassay | Bioorg Med Chem Lett 14: 37-41 (2003) BindingDB Entry DOI: 10.7270/Q2B27TPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Holo-[acyl-carrier-protein] synthase (Bacillus subtilis) | BDBM50178648 (4-chloro-2-{[(2E)-3-(4-chlorophenyl)-2-methylprop-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibitory activity against Bacillus subtilis AcpS by HTRF assay | J Med Chem 48: 7960-9 (2005) Article DOI: 10.1021/jm050523n BindingDB Entry DOI: 10.7270/Q2W66KBJ | |||||||||||
More data for this Ligand-Target Pair |