Found 13 hits of ic50 for UniProtKB: P49764 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Placenta growth factor
(Mus musculus) | BDBM50339214
(CHEMBL1689480)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)NC1=O)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](Cc1ccc(O)cc1)C(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(C)C |r,wU:39.41,4.3,64.68,49.56,2.2,145.161,106.112,132.140,20.21,8.8,wD:56.60,100.108,117.123,99.105,136.149,35.102,30.136,(28.71,-31.85,;27.38,-32.62,;26.04,-31.85,;26.04,-30.32,;24.71,-32.63,;20.77,-34.9,;19.44,-34.12,;18.1,-34.87,;19.46,-32.59,;20.78,-31.84,;20.81,-30.3,;22.14,-29.56,;22.16,-28.02,;20.84,-27.24,;20.86,-25.7,;19.5,-27.99,;19.49,-29.52,;18.13,-31.79,;16.8,-32.55,;16.78,-34.09,;15.46,-31.76,;15.48,-30.23,;14.16,-29.44,;14.02,-27.92,;12.52,-27.58,;11.73,-28.9,;12.74,-30.05,;14.12,-32.54,;14.18,-34.02,;15.53,-34.76,;12.81,-34.79,;12.81,-36.34,;14.15,-37.14,;14.14,-38.71,;15.45,-39.53,;15.45,-41.06,;16.77,-41.84,;16.77,-43.38,;15.44,-44.14,;18.09,-44.15,;18.09,-45.7,;16.74,-46.46,;15.34,-45.83,;14.31,-46.97,;15.08,-48.31,;16.59,-47.99,;19.43,-43.4,;20.74,-44.16,;20.74,-45.7,;22.09,-43.4,;23.55,-43.87,;24.45,-42.64,;23.55,-41.4,;22.1,-41.87,;20.75,-41.12,;19.44,-41.88,;20.75,-39.58,;19.42,-38.82,;18.09,-39.59,;16.75,-38.83,;18.09,-41.13,;22.09,-38.79,;22.07,-37.26,;20.73,-36.51,;23.4,-36.48,;24.73,-37.25,;24.72,-38.79,;26.05,-39.57,;26.04,-41.12,;27.39,-41.91,;28.74,-41.13,;28.75,-39.57,;30.09,-41.91,;31.44,-41.14,;32.78,-41.92,;34.14,-41.14,;34.14,-39.59,;35.48,-41.93,;36.83,-41.15,;38.17,-41.94,;39.52,-41.16,;39.53,-39.61,;40.88,-38.83,;42.22,-39.61,;43.57,-38.83,;43.57,-37.28,;44.92,-39.61,;45.32,-41.11,;46.82,-40.71,;46.42,-39.2,;47.2,-37.86,;38.17,-38.82,;36.83,-39.6,;23.43,-34.93,;24.73,-34.18,;26.05,-34.93,;14.11,-41.84,;14.11,-43.36,;12.79,-41.07,;11.45,-41.84,;11.45,-43.37,;10.13,-44.15,;12.79,-44.14,;10.13,-41.06,;10.13,-39.52,;8.79,-41.84,;7.45,-41.06,;7.45,-39.52,;6.11,-38.75,;4.79,-39.53,;3.46,-38.76,;2.12,-39.53,;.8,-38.77,;2.13,-41.07,;6.11,-41.84,;4.78,-41.07,;6.12,-43.37,;4.8,-44.14,;4.81,-45.7,;3.46,-46.48,;2.11,-45.71,;.77,-46.49,;.78,-48.05,;-.57,-48.83,;2.13,-48.82,;3.47,-48.03,;3.46,-43.38,;2.13,-44.16,;3.46,-41.84,;11.49,-34.02,;10.15,-34.77,;10.15,-36.31,;8.81,-34.01,;7.47,-34.78,;6.16,-34.02,;6.15,-32.49,;4.8,-34.8,;4.82,-36.33,;3.5,-37.12,;2.16,-36.36,;.85,-37.15,;2.14,-34.83,;3.5,-34.03,;3.5,-32.5,;4.84,-31.73,;2.17,-31.72,;2.19,-30.19,;3.52,-29.43,;4.84,-30.2,;6.18,-29.44,;6.19,-27.9,;4.85,-27.13,;3.52,-27.89,;.84,-32.48,;-.49,-31.71,;-1.83,-32.48,;-.49,-30.16,;8.81,-32.48,;7.47,-31.71,;10.13,-31.7,)| Show InChI InChI=1S/C106H146N26O26S2/c1-9-59(6)89-103(155)119-71(19-13-14-39-112-83(137)51-158-52-84(138)117-66-29-22-62(23-30-66)28-36-85(139)132-42-38-86(132)140)93(145)125-79(43-57(2)3)105(157)131-41-16-21-82(131)101(153)124-78(48-68-50-111-56-115-68)97(149)126-81(100(152)130-90(60(7)133)104(156)120-72(20-15-40-113-106(108)109)92(144)121-74(91(107)143)44-64-24-31-69(135)32-25-64)54-160-159-53-80(99(151)123-77(47-67-49-110-55-114-67)96(148)122-76(98(150)129-89)46-65-26-33-70(136)34-27-65)127-102(154)88(58(4)5)128-94(146)73(35-37-87(141)142)118-95(147)75(116-61(8)134)45-63-17-11-10-12-18-63/h10-12,17-18,22-27,29-34,49-50,55-60,71-82,88-90,133,135-136H,9,13-16,19-21,28,35-48,51-54H2,1-8H3,(H2,107,143)(H,110,114)(H,111,115)(H,112,137)(H,116,134)(H,117,138)(H,118,147)(H,119,155)(H,120,156)(H,121,144)(H,122,148)(H,123,151)(H,124,153)(H,125,145)(H,126,149)(H,127,154)(H,128,146)(H,129,150)(H,130,152)(H,141,142)(H4,108,109,113)/t59-,60+,71-,72+,73-,74+,75-,76-,77-,78-,79-,80-,81-,82-,88-,89-,90+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
Placenta growth factor
(Mus musculus) | BDBM50339209
(CHEMBL1689479)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(C)C |r,wU:4.3,64.68,49.56,2.2,145.161,117.123,99.105,132.140,20.21,8.8,39.41,wD:56.60,100.108,106.112,136.149,35.102,30.136,(16.25,-25.17,;14.91,-25.94,;13.58,-25.18,;13.58,-23.65,;12.25,-25.96,;8.31,-28.23,;6.97,-27.45,;5.63,-28.2,;6.99,-25.91,;8.32,-25.16,;8.34,-23.62,;9.68,-22.88,;9.7,-21.35,;8.38,-20.56,;8.4,-19.02,;7.04,-21.32,;7.02,-22.85,;5.67,-25.12,;4.34,-25.88,;4.32,-27.42,;2.99,-25.09,;3.01,-23.56,;1.69,-22.77,;1.55,-21.25,;.05,-20.91,;-.73,-22.23,;.28,-23.39,;1.66,-25.86,;1.72,-27.35,;3.06,-28.09,;.35,-28.11,;.34,-29.66,;1.68,-30.47,;1.67,-32.03,;2.98,-32.85,;2.98,-34.39,;4.31,-35.17,;4.31,-36.71,;2.97,-37.47,;5.63,-37.48,;5.62,-39.03,;4.28,-39.79,;2.88,-39.16,;1.85,-40.3,;2.61,-41.64,;4.12,-41.32,;6.97,-36.72,;8.28,-37.49,;8.28,-39.03,;9.63,-36.73,;11.08,-37.21,;11.99,-35.97,;11.09,-34.73,;9.63,-35.2,;8.29,-34.44,;6.97,-35.21,;8.29,-32.9,;6.95,-32.14,;5.63,-32.92,;4.29,-32.16,;5.63,-34.46,;9.63,-32.12,;9.61,-30.59,;8.27,-29.83,;10.94,-29.81,;12.27,-30.58,;12.26,-32.12,;13.59,-32.89,;13.58,-34.45,;14.93,-35.23,;16.28,-34.46,;16.28,-32.9,;17.62,-35.24,;18.97,-34.47,;20.32,-35.25,;21.67,-34.47,;21.67,-32.91,;23.02,-35.25,;24.37,-34.48,;25.71,-35.27,;27.06,-34.49,;27.07,-32.93,;28.41,-32.16,;29.76,-32.94,;31.11,-32.16,;31.11,-30.6,;32.46,-32.94,;32.86,-34.44,;34.36,-34.04,;33.96,-32.54,;34.74,-31.19,;25.71,-32.15,;24.37,-32.93,;10.97,-28.26,;12.26,-27.51,;13.59,-28.26,;1.65,-35.17,;1.65,-36.69,;.32,-34.4,;-1.01,-35.17,;-1.01,-36.7,;-2.34,-37.47,;.32,-37.47,;-2.34,-34.38,;-2.34,-32.85,;-3.68,-35.17,;-5.01,-34.38,;-5.02,-32.85,;-6.35,-32.08,;-7.68,-32.86,;-9.01,-32.09,;-10.34,-32.86,;-11.68,-32.09,;-10.34,-34.39,;-6.35,-35.17,;-7.68,-34.4,;-6.34,-36.7,;-7.67,-37.47,;-7.66,-39.03,;-9,-39.81,;-10.35,-39.03,;-11.7,-39.82,;-11.71,-41.38,;-13.04,-42.16,;-10.33,-42.15,;-8.99,-41.36,;-9.01,-36.71,;-10.34,-37.48,;-9.01,-35.17,;-.97,-27.34,;-2.31,-28.09,;-2.31,-29.63,;-3.65,-27.34,;-5,-28.1,;-6.31,-27.35,;-6.32,-25.82,;-7.67,-28.12,;-7.65,-29.66,;-8.97,-30.44,;-10.31,-29.69,;-11.64,-30.47,;-10.32,-28.16,;-8.97,-27.36,;-8.96,-25.83,;-7.63,-25.06,;-10.29,-25.05,;-10.28,-23.51,;-8.94,-22.75,;-7.62,-23.53,;-6.29,-22.76,;-6.28,-21.23,;-7.61,-20.46,;-8.94,-21.22,;-11.63,-25.81,;-12.98,-25.03,;-14.33,-25.81,;-12.98,-23.48,;-3.66,-25.8,;-4.99,-25.03,;-2.33,-25.03,)| Show InChI InChI=1S/C106H146N26O26S2/c1-9-59(6)89-103(155)119-71(19-13-14-39-112-83(137)51-158-52-84(138)117-66-29-22-62(23-30-66)28-36-85(139)132-42-38-86(132)140)93(145)125-79(43-57(2)3)105(157)131-41-16-21-82(131)101(153)124-78(48-68-50-111-56-115-68)97(149)126-81(100(152)130-90(60(7)133)104(156)120-72(20-15-40-113-106(108)109)92(144)121-74(91(107)143)44-64-24-31-69(135)32-25-64)54-160-159-53-80(99(151)123-77(47-67-49-110-55-114-67)96(148)122-76(98(150)129-89)46-65-26-33-70(136)34-27-65)127-102(154)88(58(4)5)128-94(146)73(35-37-87(141)142)118-95(147)75(116-61(8)134)45-63-17-11-10-12-18-63/h10-12,17-18,22-27,29-34,49-50,55-60,71-82,88-90,133,135-136H,9,13-16,19-21,28,35-48,51-54H2,1-8H3,(H2,107,143)(H,110,114)(H,111,115)(H,112,137)(H,116,134)(H,117,138)(H,118,147)(H,119,155)(H,120,156)(H,121,144)(H,122,148)(H,123,151)(H,124,153)(H,125,145)(H,126,149)(H,127,154)(H,128,146)(H,129,150)(H,130,152)(H,141,142)(H4,108,109,113)/t59-,60+,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,88-,89-,90-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
Placenta growth factor
(Mus musculus) | BDBM50339193
(CHEMBL1689463)Show SMILES CSCC[C@H](NC(=O)[C@H](CCCCNC(=O)COCC(=O)Nc1ccc(CCC(=O)N2CCC2=O)cc1)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(N)=O |r| Show InChI InChI=1S/C102H144N24O26S3/c1-54(2)41-75-102(151)125-38-20-27-78(125)98(147)118-72(44-64-48-105-53-109-64)92(141)120-76(96(145)114-69(25-16-18-36-106-58(8)128)90(139)113-68(89(138)112-67(88(104)137)35-40-153-10)26-17-19-37-107-80(131)49-152-50-81(132)111-63-31-28-60(29-32-63)30-33-82(133)126-39-34-83(126)134)51-154-155-52-77(121-99(148)85(55(3)4)122-95(144)74(46-84(135)136)117-91(140)70(110-59(9)129)42-61-21-12-11-13-22-61)97(146)116-73(45-79(103)130)93(142)115-71(43-62-47-108-66-24-15-14-23-65(62)66)94(143)123-86(56(5)6)100(149)124-87(57(7)127)101(150)119-75/h11-15,21-24,28-29,31-32,47-48,53-57,67-78,85-87,108,127H,16-20,25-27,30,33-46,49-52H2,1-10H3,(H2,103,130)(H2,104,137)(H,105,109)(H,106,128)(H,107,131)(H,110,129)(H,111,132)(H,112,138)(H,113,139)(H,114,145)(H,115,142)(H,116,146)(H,117,140)(H,118,147)(H,119,150)(H,120,141)(H,121,148)(H,122,144)(H,123,143)(H,124,149)(H,135,136)/t57-,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,77+,78+,85+,86+,87+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
Placenta growth factor
(Mus musculus) | BDBM50339201
(CHEMBL1689470)Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O |r| Show InChI InChI=1S/C103H146N24O25S3/c1-55(2)42-76-103(151)126-39-21-28-79(126)99(147)119-73(45-65-49-106-54-110-65)93(141)121-77(97(145)114-70(27-17-19-37-107-59(9)128)91(139)123-86(56(3)4)100(148)113-68(89(105)137)36-41-153-11)52-154-155-53-78(122-102(150)88(58(7)8)125-96(144)75(47-85(135)136)118-92(140)71(111-60(10)129)43-62-22-13-12-14-23-62)98(146)117-74(46-80(104)130)94(142)116-72(44-63-48-109-67-25-16-15-24-66(63)67)95(143)124-87(57(5)6)101(149)115-69(90(138)120-76)26-18-20-38-108-81(131)50-152-51-82(132)112-64-32-29-61(30-33-64)31-34-83(133)127-40-35-84(127)134/h12-16,22-25,29-30,32-33,48-49,54-58,68-79,86-88,109H,17-21,26-28,31,34-47,50-53H2,1-11H3,(H2,104,130)(H2,105,137)(H,106,110)(H,107,128)(H,108,131)(H,111,129)(H,112,132)(H,113,148)(H,114,145)(H,115,149)(H,116,142)(H,117,146)(H,118,140)(H,119,147)(H,120,138)(H,121,141)(H,122,150)(H,123,139)(H,124,143)(H,125,144)(H,135,136)/t68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,86-,87-,88-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
Placenta growth factor
(Mus musculus) | BDBM50339197
(CHEMBL1689466)Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(=O)COCC(=O)Nc1ccc(CCC(=O)N2CCC2=O)cc1)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O |r| Show InChI InChI=1S/C99H139N23O25S3/c1-51(2)38-71-99(146)121-35-19-25-74(121)94(141)113-68(41-61-45-102-50-105-61)88(135)115-72(92(139)109-65(86(133)117-81(52(3)4)95(142)108-64(85(101)132)33-37-148-11)24-17-18-34-103-76(126)46-147-47-77(127)107-60-29-26-57(27-30-60)28-31-78(128)122-36-32-79(122)129)48-149-150-49-73(116-96(143)82(53(5)6)118-91(138)70(43-80(130)131)112-87(134)66(106-56(10)124)39-58-20-13-12-14-21-58)93(140)111-69(42-75(100)125)89(136)110-67(40-59-44-104-63-23-16-15-22-62(59)63)90(137)119-83(54(7)8)97(144)120-84(55(9)123)98(145)114-71/h12-16,20-23,26-27,29-30,44-45,50-55,64-74,81-84,104,123H,17-19,24-25,28,31-43,46-49H2,1-11H3,(H2,100,125)(H2,101,132)(H,102,105)(H,103,126)(H,106,124)(H,107,127)(H,108,142)(H,109,139)(H,110,136)(H,111,140)(H,112,134)(H,113,141)(H,114,145)(H,115,135)(H,116,143)(H,117,133)(H,118,138)(H,119,137)(H,120,144)(H,130,131)/t55-,64+,65+,66+,67+,68+,69+,70+,71+,72+,73+,74+,81+,82+,83+,84+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
Placenta growth factor
(Mus musculus) | BDBM50339213
(CHEMBL1689478)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(C)C |r,wU:20.21,8.8,39.41,4.3,64.68,49.56,2.2,124.138,96.100,78.82,111.117,wD:56.60,79.85,85.89,115.126,35.79,30.113,(24.33,-18.35,;22.99,-19.12,;21.66,-18.36,;21.65,-16.82,;20.32,-19.14,;16.38,-21.41,;15.04,-20.63,;13.7,-21.38,;15.06,-19.1,;16.39,-18.34,;16.41,-16.8,;17.75,-16.06,;17.77,-14.52,;16.44,-13.74,;16.47,-12.19,;15.1,-14.49,;15.09,-16.03,;13.73,-18.3,;12.4,-19.06,;12.38,-20.6,;11.05,-18.27,;11.07,-16.73,;9.75,-15.94,;9.61,-14.42,;8.11,-14.08,;7.32,-15.4,;8.33,-16.56,;9.72,-19.05,;9.77,-20.53,;11.12,-21.27,;8.41,-21.3,;8.4,-22.85,;9.74,-23.65,;9.73,-25.22,;11.04,-26.05,;11.04,-27.59,;12.37,-28.37,;12.37,-29.91,;11.03,-30.67,;13.69,-30.67,;13.69,-32.23,;12.34,-32.99,;10.94,-32.36,;9.91,-33.51,;10.67,-34.84,;12.18,-34.53,;15.03,-29.92,;16.35,-30.69,;16.34,-32.23,;17.7,-29.93,;19.15,-30.41,;20.06,-29.17,;19.16,-27.92,;17.7,-28.39,;16.36,-27.64,;15.04,-28.4,;16.36,-26.1,;15.02,-25.33,;13.69,-26.11,;12.35,-25.35,;13.69,-27.65,;17.7,-25.31,;17.68,-23.78,;16.34,-23.02,;19.01,-23,;20.34,-23.77,;20.33,-25.31,;21.66,-26.09,;23,-25.32,;24.33,-26.1,;25.66,-25.33,;24.32,-27.63,;19.04,-21.44,;20.33,-20.69,;21.67,-21.45,;9.7,-28.36,;9.7,-29.89,;8.38,-27.59,;7.05,-28.36,;7.05,-29.9,;5.71,-30.67,;8.38,-30.66,;5.71,-27.58,;5.71,-26.04,;4.37,-28.36,;3.04,-27.58,;3.03,-26.04,;1.69,-25.27,;.37,-26.05,;-.96,-25.28,;-2.3,-26.05,;-3.63,-25.28,;-2.3,-27.59,;1.69,-28.36,;.36,-27.6,;1.7,-29.9,;.38,-30.67,;.38,-32.23,;-.96,-33.01,;-2.31,-32.24,;-3.66,-33.02,;-3.65,-34.58,;-5,-35.37,;-2.29,-35.35,;-.95,-34.57,;-.96,-29.9,;-2.3,-30.68,;-.96,-28.37,;7.09,-20.53,;5.74,-21.28,;5.74,-22.82,;4.4,-20.52,;3.05,-21.29,;1.74,-20.53,;1.73,-19,;.38,-21.31,;.4,-22.84,;-.92,-23.63,;-2.27,-22.88,;-3.58,-23.66,;-2.28,-21.34,;-.92,-20.54,;-.92,-19.01,;.42,-18.24,;-2.25,-18.23,;-2.24,-16.69,;-.9,-15.93,;.42,-16.71,;1.75,-15.94,;1.77,-14.4,;.43,-13.63,;-.9,-14.39,;-3.58,-18.99,;-4.93,-18.21,;-6.29,-18.99,;-4.93,-16.66,;4.39,-18.99,;3.05,-18.21,;5.72,-18.21,)| Show InChI InChI=1S/C90H130N26O21S2/c1-9-48(6)72-86(135)104-59(19-14-32-99-90(94)95)76(125)110-66(34-46(2)3)88(137)116-33-15-20-69(116)84(133)109-65(39-55-41-97-45-101-55)80(129)111-68(83(132)115-73(49(7)117)87(136)105-58(18-13-31-98-89(92)93)75(124)106-61(74(91)123)35-52-21-25-56(119)26-22-52)43-139-138-42-67(82(131)108-64(38-54-40-96-44-100-54)79(128)107-63(81(130)114-72)37-53-23-27-57(120)28-24-53)112-85(134)71(47(4)5)113-77(126)60(29-30-70(121)122)103-78(127)62(102-50(8)118)36-51-16-11-10-12-17-51/h10-12,16-17,21-28,40-41,44-49,58-69,71-73,117,119-120H,9,13-15,18-20,29-39,42-43H2,1-8H3,(H2,91,123)(H,96,100)(H,97,101)(H,102,118)(H,103,127)(H,104,135)(H,105,136)(H,106,124)(H,107,128)(H,108,131)(H,109,133)(H,110,125)(H,111,129)(H,112,134)(H,113,126)(H,114,130)(H,115,132)(H,121,122)(H4,92,93,98)(H4,94,95,99)/t48-,49+,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,71-,72-,73-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
Placenta growth factor
(Mus musculus) | BDBM50339204
(CHEMBL1689473)Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O |r| Show InChI InChI=1S/C103H147N23O25S3/c1-55(2)43-76-103(150)125-40-22-29-79(125)98(145)117-74(46-66-49-105-54-109-66)93(140)119-77(96(143)114-71(28-18-20-38-106-60(10)128)91(138)121-85(56(3)4)99(146)112-69(89(104)136)37-42-152-12)52-153-154-53-78(120-100(147)86(57(5)6)122-95(142)75(47-84(134)135)116-92(139)72(110-61(11)129)44-63-23-14-13-15-24-63)97(144)113-70(27-19-21-39-107-80(130)50-151-51-81(131)111-65-33-30-62(31-34-65)32-35-82(132)126-41-36-83(126)133)90(137)115-73(45-64-48-108-68-26-17-16-25-67(64)68)94(141)123-87(58(7)8)101(148)124-88(59(9)127)102(149)118-76/h13-17,23-26,30-31,33-34,48-49,54-59,69-79,85-88,108,127H,18-22,27-29,32,35-47,50-53H2,1-12H3,(H2,104,136)(H,105,109)(H,106,128)(H,107,130)(H,110,129)(H,111,131)(H,112,146)(H,113,144)(H,114,143)(H,115,137)(H,116,139)(H,117,145)(H,118,149)(H,119,140)(H,120,147)(H,121,138)(H,122,142)(H,123,141)(H,124,148)(H,134,135)/t59-,69+,70+,71+,72+,73+,74+,75+,76+,77+,78+,79+,85+,86+,87+,88+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 624 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
Placenta growth factor
(Mus musculus) | BDBM50339205
(CHEMBL1689474)Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O |r| Show InChI InChI=1S/C102H144N24O26S3/c1-54(2)41-75-102(151)125-38-20-27-78(125)98(147)118-72(44-64-48-105-53-109-64)92(141)121-76(96(145)114-69(26-16-18-36-106-58(8)128)90(139)122-85(55(3)4)99(148)112-67(88(104)137)35-40-153-10)51-154-155-52-77(97(146)116-73(45-79(103)130)93(142)115-71(43-62-47-108-66-24-15-14-23-65(62)66)95(144)123-86(56(5)6)100(149)124-87(57(7)127)101(150)119-75)120-89(138)68(113-94(143)74(46-84(135)136)117-91(140)70(110-59(9)129)42-61-21-12-11-13-22-61)25-17-19-37-107-80(131)49-152-50-81(132)111-63-31-28-60(29-32-63)30-33-82(133)126-39-34-83(126)134/h11-15,21-24,28-29,31-32,47-48,53-57,67-78,85-87,108,127H,16-20,25-27,30,33-46,49-52H2,1-10H3,(H2,103,130)(H2,104,137)(H,105,109)(H,106,128)(H,107,131)(H,110,129)(H,111,132)(H,112,148)(H,113,143)(H,114,145)(H,115,142)(H,116,146)(H,117,140)(H,118,147)(H,119,150)(H,120,138)(H,121,141)(H,122,139)(H,123,144)(H,124,149)(H,135,136)/t57-,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,77+,78+,85+,86+,87+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
Placenta growth factor
(Mus musculus) | BDBM50339203
(CHEMBL1689472)Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O |r| Show InChI InChI=1S/C96H143N23O26S3/c1-50(2)39-68-96(144)118-36-20-25-71(118)91(139)110-65(41-60-44-99-49-102-60)86(134)112-69(89(137)107-63(23-16-18-34-100-55(10)121)84(132)114-78(51(3)4)92(140)105-61(82(98)130)33-38-146-12)47-147-148-48-70(113-93(141)79(52(5)6)116-88(136)67(43-77(128)129)109-85(133)64(103-56(11)122)40-58-21-14-13-15-22-58)90(138)108-66(42-72(97)123)87(135)106-62(83(131)115-80(53(7)8)94(142)117-81(54(9)120)95(143)111-68)24-17-19-35-101-73(124)45-145-46-74(125)104-59-29-26-57(27-30-59)28-31-75(126)119-37-32-76(119)127/h13-15,21-22,26-27,29-30,44,49-54,61-71,78-81,120H,16-20,23-25,28,31-43,45-48H2,1-12H3,(H2,97,123)(H2,98,130)(H,99,102)(H,100,121)(H,101,124)(H,103,122)(H,104,125)(H,105,140)(H,106,135)(H,107,137)(H,108,138)(H,109,133)(H,110,139)(H,111,143)(H,112,134)(H,113,141)(H,114,132)(H,115,131)(H,116,136)(H,117,142)(H,128,129)/t54-,61+,62+,63+,64+,65+,66+,67+,68+,69+,70+,71+,78+,79+,80+,81+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
Placenta growth factor
(Mus musculus) | BDBM50339200
(CHEMBL1689469)Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O |r| Show InChI InChI=1S/C101H142N24O26S3/c1-53(2)83(97(146)111-66(87(103)136)35-40-152-10)120-88(137)67(25-16-18-36-105-57(8)127)112-94(143)74-50-153-154-51-75(119-98(147)84(54(3)4)121-93(142)73(45-82(134)135)116-89(138)69(109-58(9)128)41-60-21-12-11-13-22-60)95(144)115-72(44-77(102)129)91(140)114-70(42-61-46-107-65-24-15-14-23-64(61)65)92(141)122-85(55(5)6)99(148)123-86(56(7)126)100(149)113-68(101(150)124-38-20-27-76(124)96(145)117-71(90(139)118-74)43-63-47-104-52-108-63)26-17-19-37-106-78(130)48-151-49-79(131)110-62-31-28-59(29-32-62)30-33-80(132)125-39-34-81(125)133/h11-15,21-24,28-29,31-32,46-47,52-56,66-76,83-86,107,126H,16-20,25-27,30,33-45,48-51H2,1-10H3,(H2,102,129)(H2,103,136)(H,104,108)(H,105,127)(H,106,130)(H,109,128)(H,110,131)(H,111,146)(H,112,143)(H,113,149)(H,114,140)(H,115,144)(H,116,138)(H,117,145)(H,118,139)(H,119,147)(H,120,137)(H,121,142)(H,122,141)(H,123,148)(H,134,135)/t56-,66+,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,83+,84+,85+,86+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
Placenta growth factor
(Mus musculus) | BDBM50339199
(CHEMBL1689468)Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O |r| Show InChI InChI=1S/C102H146N24O26S3/c1-53(2)40-70-91(140)113-68(26-19-21-37-107-79(131)48-152-49-80(132)111-63-31-28-60(29-32-63)30-33-81(133)126-38-34-82(126)134)89(138)116-73(43-64-47-105-52-109-64)93(142)120-76(97(146)114-69(27-18-20-36-106-58(10)128)90(139)122-84(54(3)4)99(148)112-67(88(104)137)35-39-153-12)50-154-155-51-77(121-100(149)85(55(5)6)123-96(145)75(45-83(135)136)118-92(141)71(110-59(11)129)41-61-22-14-13-15-23-61)98(147)117-74(44-78(103)130)94(143)115-72(42-62-46-108-66-25-17-16-24-65(62)66)95(144)124-86(56(7)8)101(150)125-87(57(9)127)102(151)119-70/h13-17,22-25,28-29,31-32,46-47,52-57,67-77,84-87,108,127H,18-21,26-27,30,33-45,48-51H2,1-12H3,(H2,103,130)(H2,104,137)(H,105,109)(H,106,128)(H,107,131)(H,110,129)(H,111,132)(H,112,148)(H,113,140)(H,114,146)(H,115,143)(H,116,138)(H,117,147)(H,118,141)(H,119,151)(H,120,142)(H,121,149)(H,122,139)(H,123,145)(H,124,144)(H,125,150)(H,135,136)/t57-,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,77+,84+,85+,86+,87+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
Placenta growth factor
(Mus musculus) | BDBM50339198
(CHEMBL1689467)Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N1)C(C)C)C(N)=O |r| Show InChI InChI=1S/C101H146N22O26S3/c1-53(2)43-73-101(148)122-40-22-29-76(122)96(143)111-67(27-19-21-39-105-78(128)49-149-50-79(129)108-63-33-30-60(31-34-63)32-35-80(130)123-41-36-81(123)131)88(135)116-74(94(141)110-68(28-18-20-38-104-58(10)125)89(136)118-83(54(3)4)97(144)109-66(87(103)134)37-42-150-12)51-151-152-52-75(117-98(145)84(55(5)6)119-93(140)72(47-82(132)133)114-90(137)69(107-59(11)126)44-61-23-14-13-15-24-61)95(142)113-71(46-77(102)127)91(138)112-70(45-62-48-106-65-26-17-16-25-64(62)65)92(139)120-85(56(7)8)99(146)121-86(57(9)124)100(147)115-73/h13-17,23-26,30-31,33-34,48,53-57,66-76,83-86,106,124H,18-22,27-29,32,35-47,49-52H2,1-12H3,(H2,102,127)(H2,103,134)(H,104,125)(H,105,128)(H,107,126)(H,108,129)(H,109,144)(H,110,141)(H,111,143)(H,112,138)(H,113,142)(H,114,137)(H,115,147)(H,116,135)(H,117,145)(H,118,136)(H,119,140)(H,120,139)(H,121,146)(H,132,133)/t57-,66+,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,83+,84+,85+,86+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
Placenta growth factor
(Mus musculus) | BDBM50339202
(CHEMBL1689471)Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCNC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O |r| Show InChI InChI=1S/C102H144N24O26S3/c1-54(2)41-75-102(151)125-38-20-27-78(125)98(147)118-72(44-64-48-105-53-109-64)93(142)120-76(96(145)114-68(25-16-18-36-106-58(8)128)89(138)122-85(55(3)4)99(148)112-67(88(104)137)35-40-153-10)51-154-155-52-77(121-100(149)86(56(5)6)123-95(144)74(46-84(135)136)117-91(140)70(110-59(9)129)42-61-21-12-11-13-22-61)97(146)116-73(45-79(103)130)94(143)115-71(43-62-47-108-66-24-15-14-23-65(62)66)92(141)113-69(90(139)124-87(57(7)127)101(150)119-75)26-17-19-37-107-80(131)49-152-50-81(132)111-63-31-28-60(29-32-63)30-33-82(133)126-39-34-83(126)134/h11-15,21-24,28-29,31-32,47-48,53-57,67-78,85-87,108,127H,16-20,25-27,30,33-46,49-52H2,1-10H3,(H2,103,130)(H2,104,137)(H,105,109)(H,106,128)(H,107,131)(H,110,129)(H,111,132)(H,112,148)(H,113,141)(H,114,145)(H,115,143)(H,116,146)(H,117,140)(H,118,147)(H,119,150)(H,120,142)(H,121,149)(H,122,138)(H,123,144)(H,124,139)(H,135,136)/t57-,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,77+,78+,85+,86+,87+/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA |
J Med Chem 54: 1256-65 (2011)
Article DOI: 10.1021/jm101226k
BindingDB Entry DOI: 10.7270/Q2BK1CN1 |
More data for this
Ligand-Target Pair | |
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