Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289495 (1-(4-(6-amino-5-(tri- fluoromethyl)pyridin-3- yl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM590003 ((S)-1-(4-(6-amino-5- (trifluoromethyl)pyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM589995 ((R)-1-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM589991 (US11560366, Example 3b) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289483 (1-(4-(6-amino-5- (trifluoromethyl)- pyridin-3-yl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM590004 ((S)-1-(4-(6-amino-5- (trifluoromethoxy)pyridin-3-y...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM589992 ((S)-1-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289483 (1-(4-(6-amino-5- (trifluoromethyl)- pyridin-3-yl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289429 ((S)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289505 (1-(4-(6-amino-5-(tri- fluoromethyl)pyridin-3- yl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289428 ((S)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289428 ((S)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM589996 ((R)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289481 (1-(4-(6-amino-5-(tri- fluoromethoxy)pyridin- 3-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM589998 (US11560366, Example 10a) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289426 ( (R)-1-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.740 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM589997 (US11560366, Example 9b) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289481 (1-(4-(6-amino-5-(tri- fluoromethoxy)pyridin- 3-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM590001 ((R)-1-(4-(6-amino-5-(trifluoromethoxy)- pyridin-3-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289491 (1-(4-(6-amino-5- (trifluoromethoxy)- pyridin-3-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289437 (4-(3-(2-cyclopropyl-4-(3-(trifluoromethyl)-1H-pyrr...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289489 (1-(4-(6-amino-5-(tri- fluoromethyl)pyridin-3- yl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM589988 ((R)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289425 ((R)-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)-1...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289484 ((4-(6-amino-5-(trifluoro- methyl)pyridin-3- yl)-1-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM590000 ((4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)-1-(3-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289447 (4-(3-(2-isopropyl-4-(1-(1-(pyridin-2-yl)ethyl)-1H-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM589999 ((4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl)-1-(3...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289466 (5-(2-(cyclopropyl- methyl)-1-(3-(4- methylpiperazi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM589990 ((R)-1-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289509 (5-(2-isopropyl-1-(3-(4- methylpiperazin-1-yl)- bic...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289480 ((4-(6-amino-5-(tri- fluoromethoxy)pyridin- 3-yl)-1...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM50271212 (CHEMBL3715238) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a |
WuXi AppTec Co., Ltd. Curated by ChEMBL | Assay Description Binding affinity to full length wild type human DLK (M1 to P859 residues) expressed in mammalian cells by KINOMEscan assay | J Med Chem 60: 8083-8102 (2017) Article DOI: 10.1021/acs.jmedchem.7b00843 BindingDB Entry DOI: 10.7270/Q2639S7K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM589993 (US11560366, Example 5) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289471 (5-(2-isobutyl-1-(3- morpholinobicyclo- [1.1.1]pent...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289444 (5-(1-(3-(bis(2-methoxyethyl)amino)bicyclo[1.1.1]pe...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289455 (5-(1-(3-morpholino- bicyclo[1.1.1]pentan-1- yl)-2-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289443 (5-(2-cyclopropyl-1-(3-((2-methoxyethyl)(methyl)ami...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289436 (5-(2-cyclopropyl-1-(3-(4-(2-fluoroethyl)piperazin-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289445 (1-(3-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289458 (5-(2-(cyclopropyl- methyl)-1-(3-morpho- linobicycl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289511 (5-(2-cyclopropyl-1-(3- (4-methylpiperazin-1- yl)bi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289510 (5-(2-cyclopropyl-1-(3- (4-methylpiperazin-1- yl)bi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM589994 (US11560366, Example 6) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c... | Citation and Details BindingDB Entry DOI: 10.7270/Q21C21S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289424 (US10093664, Example 4) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289473 (5-(2-(sec-butyl)-1-(3- morpholinobicyclo- [1.1.1]p...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289474 (5-(2-(sec-butyl)-1-(3- morpholinobicyclo- [1.1.1]p...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289441 (4-(3-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289456 ((S)-1-(4-(6-amino-5- (trifluoromethyl)- pyridin-3-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM289423 (5-(2-isopropyl-1-(3-morpholinobicyclo[1.1.1]pentan...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System US Patent | Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... | US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |
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