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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for UniProtKB: A5Z1V5   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cell division protein FtsZ


(Bacillus subtilis)		BDBM25525
PNG
(24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...)
Show SMILES C[n+]1cc2c3OCOc3ccc2c2ccc3cc4OCOc4cc3c12
Show InChI InChI=1S/C20H14NO4/c1-21-8-15-12(4-5-16-20(15)25-10-22-16)13-3-2-11-6-17-18(24-9-23-17)7-14(11)19(13)21/h2-8H,9-10H2,1H3/q+1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
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CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

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Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FtsZ in Bacillus subtilis assessed as disruption of Z ring formation

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113480
BindingDB Entry DOI: 10.7270/Q2474FP4
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Bacillus subtilis)		BDBM50439496
PNG
(CHEMBL2418096 | US9169182, J23)
Show SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl
Show InChI InChI=1S/C18H18Cl2O4/c1-23-17-10-16(20)18(24-2)8-12(17)3-4-13(19)5-11-6-14(21)9-15(22)7-11/h4,6-10,21-22H,3,5H2,1-2H3/b13-4+
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.00E+4n/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Inhibition of Bacillus subtilis FtsZ GTPase activity assessed as production of inorganic phosphate measured up to 60 mins by malachite green-phosphom...

Bioorg Med Chem 21: 5673-8 (2013)


Article DOI: 10.1016/j.bmc.2013.07.033
BindingDB Entry DOI: 10.7270/Q2057HC4
More data for this
Ligand-Target Pair