| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division protein FtsZ |
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| Ligand | BDBM25525 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2128842 (CHEMBL4838271) |
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| IC50 | 3000±n/a nM |
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| Citation |  Song, D; Zhang, N; Zhang, P; Zhang, N; Chen, W; Zhang, L; Guo, T; Gu, X; Ma, S Design, synthesis and evaluation of novel 9-arylalkyl-10-methylacridinium derivatives as highly potent FtsZ-targeting antibacterial agents. Eur J Med Chem221:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cell division protein FtsZ |
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| Name: | Cell division protein FtsZ |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40375.29 |
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| Organism: | Bacillus subtilis |
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| Description: | ChEMBL_107642 |
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| Residue: | 382 |
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| Sequence: | MLEFETNIDGLASIKVIGVGGGGNNAVNRMIENEVQGVEYIAVNTDAQALNLSKAEVKMQ
IGAKLTRGLGAGANPEVGKKAAEESKEQIEEALKGADMVFVTAGMGGGTGTGAAPVIAQI
AKDLGALTVGVVTRPFTFEGRKRQLQAAGGISAMKEAVDTLIVIPNDRILEIVDKNTPML
EAFREADNVLRQGVQGISDLIATPGLINLDFADVKTIMSNKGSALMGIGIATGENRAAEA
AKKAISSPLLEAAIDGAQGVLMNITGGTNLSLYEVQEAADIVASASDQDVNMIFGSVINE
NLKDEIVVTVIATGFIEQEKDVTKSQRPSLNQSIKTHNQSVPKREPKREEPQQQNTVSRH
TSQPADDTLDIPTFLRNRNKRG
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| BDBM25525 |
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| n/a |
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| Name | BDBM25525 |
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| Synonyms: | 24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{14,22}.0^{17,21}]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21),23-nonaen-24-ium | CHEMBL490129 | Pseudochelerythrine | Veadent | cid_5154 | sanguinarine | sangvinarin |
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| Type | Small organic molecule |
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| Emp. Form. | C20H14NO4 |
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| Mol. Mass. | 332.3289 |
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| SMILES | C[n+]1cc2c3OCOc3ccc2c2ccc3cc4OCOc4cc3c12 |
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| Structure | 
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