Compile Data Set for Download or QSAR

Found 107 hits of ic50 for UniProtKB: P17174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50589298 (CHEMBL5182428) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1cc(\[#6]=[#6]-2/[#8]-[#6](=O)-[#6](=[#6]-2-[#8])-c2cc(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])cc2-[#8])ccc1-[#8] |c:13| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128883 BindingDB Entry DOI: 10.7270/Q2668J40
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50048803 (5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...) Show SMILES Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128883 BindingDB Entry DOI: 10.7270/Q2668J40
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50589299 (CHEMBL5170907) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1cc(\[#6]=[#6]-2/[#8]-[#6](=O)-[#6](=[#6]-2-[#8])-c2ccc(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2)ccc1-[#8] |c:13| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	5.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128883 BindingDB Entry DOI: 10.7270/Q2668J40
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50589293 (CHEMBL5203489) Show SMILES NC1Cc2ccccc2N(O)C1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128883 BindingDB Entry DOI: 10.7270/Q2668J40
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462535 (CHEMBL4238792) Show SMILES Clc1ccc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)cc1 Show InChI InChI=1S/C19H19ClN4O/c20-14-4-6-15(7-5-14)22-19(25)24-12-10-23(11-13-24)18-3-1-2-17-16(18)8-9-21-17/h1-9,21H,10-13H2,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462533 (CHEMBL4244961) Show SMILES FC(F)(F)c1cccc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)c1 Show InChI InChI=1S/C20H19F3N4O/c21-20(22,23)14-3-1-4-15(13-14)25-19(28)27-11-9-26(10-12-27)18-6-2-5-17-16(18)7-8-24-17/h1-8,13,24H,9-12H2,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462496 (CHEMBL4246401) Show SMILES Brc1ccc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)cc1 Show InChI InChI=1S/C19H19BrN4O/c20-14-4-6-15(7-5-14)22-19(25)24-12-10-23(11-13-24)18-3-1-2-17-16(18)8-9-21-17/h1-9,21H,10-13H2,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462466 (CHEMBL4237572) Show SMILES CC(=O)c1ccc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)cc1 Show InChI InChI=1S/C21H22N4O2/c1-15(26)16-5-7-17(8-6-16)23-21(27)25-13-11-24(12-14-25)20-4-2-3-19-18(20)9-10-22-19/h2-10,22H,11-14H2,1H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462473 (CHEMBL4245427) Show SMILES FC(F)(F)c1ccc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)cc1 Show InChI InChI=1S/C20H19F3N4O/c21-20(22,23)14-4-6-15(7-5-14)25-19(28)27-12-10-26(11-13-27)18-3-1-2-17-16(18)8-9-24-17/h1-9,24H,10-13H2,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462524 (CHEMBL4239993) Show SMILES O=C(Nc1ccc(cc1)C#N)N1CCN(CC1)c1cccc2[nH]ccc12 Show InChI InChI=1S/C20H19N5O/c21-14-15-4-6-16(7-5-15)23-20(26)25-12-10-24(11-13-25)19-3-1-2-18-17(19)8-9-22-18/h1-9,22H,10-13H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50048280 (6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic ac...) Show SMILES COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O |TLB:7:8:11:15.14.13,THB:9:10:13:17.8.16,9:8:11.10.15:13,16:8:11:15.14.13,16:14:11:17.9.8| Show InChI InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128883 BindingDB Entry DOI: 10.7270/Q2668J40
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462528 (CHEMBL4249741) Show SMILES Clc1cc(Cl)cc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)c1 Show InChI InChI=1S/C19H18Cl2N4O/c20-13-10-14(21)12-15(11-13)23-19(26)25-8-6-24(7-9-25)18-3-1-2-17-16(18)4-5-22-17/h1-5,10-12,22H,6-9H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462523 (CHEMBL4241742) Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)cc1 Show InChI InChI=1S/C20H22N4O2/c1-26-16-7-5-15(6-8-16)22-20(25)24-13-11-23(12-14-24)19-4-2-3-18-17(19)9-10-21-18/h2-10,21H,11-14H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM81461 (CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...) Show SMILES NNc1nncc2ccccc12 Show InChI InChI=1S/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128883 BindingDB Entry DOI: 10.7270/Q2668J40
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM81461 (CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...) Show SMILES NNc1nncc2ccccc12 Show InChI InChI=1S/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128883 BindingDB Entry DOI: 10.7270/Q2668J40
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462553 (CHEMBL4246163) Show SMILES Brc1cccc(NC(=O)NCCc2c[nH]c3ccccc23)c1 Show InChI InChI=1S/C17H16BrN3O/c18-13-4-3-5-14(10-13)21-17(22)19-9-8-12-11-20-16-7-2-1-6-15(12)16/h1-7,10-11,20H,8-9H2,(H2,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50589296 (CHEMBL5176149) Show SMILES NNc1cccnn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128883 BindingDB Entry DOI: 10.7270/Q2668J40
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462504 (CHEMBL4237382) Show SMILES Clc1ccc(NC(=O)NCCc2c[nH]c3ccccc23)c(Cl)c1 Show InChI InChI=1S/C17H15Cl2N3O/c18-12-5-6-16(14(19)9-12)22-17(23)20-8-7-11-10-21-15-4-2-1-3-13(11)15/h1-6,9-10,21H,7-8H2,(H2,20,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462554 (CHEMBL4239818) Show SMILES O=C(NCCc1c[nH]c2ccccc12)Nc1ccccc1-c1ccccc1 Show InChI InChI=1S/C23H21N3O/c27-23(24-15-14-18-16-25-21-12-6-4-11-20(18)21)26-22-13-7-5-10-19(22)17-8-2-1-3-9-17/h1-13,16,25H,14-15H2,(H2,24,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462486 (CHEMBL4244220) Show SMILES FC(F)(F)Oc1ccc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)cc1 Show InChI InChI=1S/C20H19F3N4O2/c21-20(22,23)29-15-6-4-14(5-7-15)25-19(28)27-12-10-26(11-13-27)18-3-1-2-17-16(18)8-9-24-17/h1-9,24H,10-13H2,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462502 (CHEMBL4248460) Show SMILES Clc1ccc(NC(=O)NCCc2c[nH]c3ccccc23)cc1Cl Show InChI InChI=1S/C17H15Cl2N3O/c18-14-6-5-12(9-15(14)19)22-17(23)20-8-7-11-10-21-16-4-2-1-3-13(11)16/h1-6,9-10,21H,7-8H2,(H2,20,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462464 (CHEMBL4239817) Show SMILES Clc1ccc(NC(=O)NCCc2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C17H16ClN3O/c18-13-5-7-14(8-6-13)21-17(22)19-10-9-12-11-20-16-4-2-1-3-15(12)16/h1-8,11,20H,9-10H2,(H2,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462505 (CHEMBL4243647) Show SMILES FC(F)(F)c1ccc(NC(=O)NCCc2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C18H16F3N3O/c19-18(20,21)13-5-7-14(8-6-13)24-17(25)22-10-9-12-11-23-16-4-2-1-3-15(12)16/h1-8,11,23H,9-10H2,(H2,22,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462529 (CHEMBL4239201) Show SMILES O=C(Nc1cccc(Oc2ccccc2)c1)N1CCN(CC1)c1cccc2[nH]ccc12 Show InChI InChI=1S/C25H24N4O2/c30-25(27-19-6-4-9-21(18-19)31-20-7-2-1-3-8-20)29-16-14-28(15-17-29)24-11-5-10-23-22(24)12-13-26-23/h1-13,18,26H,14-17H2,(H,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462546 (CHEMBL4241005) Show SMILES Cc1ccc(N2CCN(CC2)C(=O)Nc2ccccc2)c2cc[nH]c12 Show InChI InChI=1S/C20H22N4O/c1-15-7-8-18(17-9-10-21-19(15)17)23-11-13-24(14-12-23)20(25)22-16-5-3-2-4-6-16/h2-10,21H,11-14H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462530 (CHEMBL4246252) Show SMILES O=C(Nc1ccc(cc1)C(=O)c1ccccc1)N1CCN(CC1)c1cccc2[nH]ccc12 Show InChI InChI=1S/C26H24N4O2/c31-25(19-5-2-1-3-6-19)20-9-11-21(12-10-20)28-26(32)30-17-15-29(16-18-30)24-8-4-7-23-22(24)13-14-27-23/h1-14,27H,15-18H2,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462477 (CHEMBL4248098) Show SMILES Clc1cc(N2CCN(CC2)C(=O)Nc2ccccc2)c2cc[nH]c2c1 Show InChI InChI=1S/C19H19ClN4O/c20-14-12-17-16(6-7-21-17)18(13-14)23-8-10-24(11-9-23)19(25)22-15-4-2-1-3-5-15/h1-7,12-13,21H,8-11H2,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50607315 (BAY-069) Show SMILES Cc1ccccc1Oc1cc(-n2c(=O)cc([nH]c2=O)C(F)(F)F)c2ccccc2c1Cl |(20.53,-12.27,;19.26,-11.42,;19.36,-9.88,;18.08,-9.03,;16.7,-9.71,;16.59,-11.25,;17.87,-12.1,;17.76,-13.64,;16.38,-14.32,;15.11,-13.47,;13.73,-14.15,;12.45,-13.3,;12.56,-11.76,;13.94,-11.08,;11.28,-10.9,;9.9,-11.59,;9.79,-13.13,;11.07,-13.98,;10.96,-15.52,;8.45,-11.09,;8.55,-9.56,;7.17,-10.24,;7.29,-12.11,;13.62,-15.7,;12.24,-16.38,;12.13,-17.91,;13.41,-18.77,;14.79,-18.09,;14.9,-16.55,;16.28,-15.87,;17.55,-16.72,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00441 BindingDB Entry DOI: 10.7270/Q2SN0F31
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462468 (CHEMBL4249221) Show SMILES Clc1cccc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)c1 Show InChI InChI=1S/C19H19ClN4O/c20-14-3-1-4-15(13-14)22-19(25)24-11-9-23(10-12-24)18-6-2-5-17-16(18)7-8-21-17/h1-8,13,21H,9-12H2,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462469 (CHEMBL4243428) Show SMILES Clc1ccc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)c(Cl)c1 Show InChI InChI=1S/C19H18Cl2N4O/c20-13-4-5-17(15(21)12-13)23-19(26)25-10-8-24(9-11-25)18-3-1-2-16-14(18)6-7-22-16/h1-7,12,22H,8-11H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462481 (CHEMBL4239412) Show SMILES FC(F)(F)c1cccc(NC(=O)NCCc2c[nH]c3ccccc23)c1 Show InChI InChI=1S/C18H16F3N3O/c19-18(20,21)13-4-3-5-14(10-13)24-17(25)22-9-8-12-11-23-16-7-2-1-6-15(12)16/h1-7,10-11,23H,8-9H2,(H2,22,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462503 (CHEMBL4244956) Show SMILES FC(F)(F)Oc1ccc(NC(=O)NCCc2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C18H16F3N3O2/c19-18(20,21)26-14-7-5-13(6-8-14)24-17(25)22-10-9-12-11-23-16-4-2-1-3-15(12)16/h1-8,11,23H,9-10H2,(H2,22,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462485 (CHEMBL4237469) Show SMILES Cc1cc(C)cc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)c1 Show InChI InChI=1S/C21H24N4O/c1-15-12-16(2)14-17(13-15)23-21(26)25-10-8-24(9-11-25)20-5-3-4-19-18(20)6-7-22-19/h3-7,12-14,22H,8-11H2,1-2H3,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50589294 (CHEMBL5182989) Show SMILES NNc1nnc(Cl)c2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128883 BindingDB Entry DOI: 10.7270/Q2668J40
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462480 (CHEMBL4237444) Show SMILES Brc1ccc(NC(=O)NCCc2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C17H16BrN3O/c18-13-5-7-14(8-6-13)21-17(22)19-10-9-12-11-20-16-4-2-1-3-15(12)16/h1-8,11,20H,9-10H2,(H2,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462525 (CHEMBL4242135) Show SMILES O=C(Nc1ccc2scnc2c1)N1CCN(CC1)c1cccc2[nH]ccc12 Show InChI InChI=1S/C20H19N5OS/c26-20(23-14-4-5-19-17(12-14)22-13-27-19)25-10-8-24(9-11-25)18-3-1-2-16-15(18)6-7-21-16/h1-7,12-13,21H,8-11H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462552 (CHEMBL4237925) Show SMILES O=C(Nc1ccccc1)N1CCN(CC1)c1cccc2[nH]ccc12 Show InChI InChI=1S/C19H20N4O/c24-19(21-15-5-2-1-3-6-15)23-13-11-22(12-14-23)18-8-4-7-17-16(18)9-10-20-17/h1-10,20H,11-14H2,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128883 BindingDB Entry DOI: 10.7270/Q2668J40
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462552 (CHEMBL4237925) Show SMILES O=C(Nc1ccccc1)N1CCN(CC1)c1cccc2[nH]ccc12 Show InChI InChI=1S/C19H20N4O/c24-19(21-15-5-2-1-3-6-15)23-13-11-22(12-14-23)18-8-4-7-17-16(18)9-10-20-17/h1-10,20H,11-14H2,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462463 (CHEMBL4248152) Show SMILES O=C(N1CCN(CC1)c1cccc2[nH]ccc12)c1ccccc1 Show InChI InChI=1S/C19H19N3O/c23-19(15-5-2-1-3-6-15)22-13-11-21(12-14-22)18-8-4-7-17-16(18)9-10-20-17/h1-10,20H,11-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462465 (CHEMBL4240748) Show SMILES COc1cc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)cc(OC)c1 Show InChI InChI=1S/C21H24N4O3/c1-27-16-12-15(13-17(14-16)28-2)23-21(26)25-10-8-24(9-11-25)20-5-3-4-19-18(20)6-7-22-19/h3-7,12-14,22H,8-11H2,1-2H3,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462467 (CHEMBL4238388) Show SMILES Clc1cccc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)c1Cl Show InChI InChI=1S/C19H18Cl2N4O/c20-14-3-1-5-16(18(14)21)23-19(26)25-11-9-24(10-12-25)17-6-2-4-15-13(17)7-8-22-15/h1-8,22H,9-12H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50163238 (4-Pyridin-4-yl-piperazine-1-carboxylic acid (4-chl...) Show SMILES Clc1ccc(NC(=O)N2CCN(CC2)c2ccncc2)cc1 Show InChI InChI=1S/C16H17ClN4O/c17-13-1-3-14(4-2-13)19-16(22)21-11-9-20(10-12-21)15-5-7-18-8-6-15/h1-8H,9-12H2,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462470 (CHEMBL4237836) Show SMILES O=C(Nc1ccccc1)N1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C16H18N4O/c21-16(18-14-4-2-1-3-5-14)20-12-10-19(11-13-20)15-6-8-17-9-7-15/h1-9H,10-13H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462471 (CHEMBL4241990) Show SMILES CNC(=O)c1cccc(NC(=O)N2CCN(CC2)c2cccc3[nH]ccc23)c1 Show InChI InChI=1S/C21H23N5O2/c1-22-20(27)15-4-2-5-16(14-15)24-21(28)26-12-10-25(11-13-26)19-7-3-6-18-17(19)8-9-23-18/h2-9,14,23H,10-13H2,1H3,(H,22,27)(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462472 (CHEMBL4237924) Show SMILES Cc1ccccc1NC(=O)N1CCN(CC1)c1cccc2[nH]ccc12 Show InChI InChI=1S/C20H22N4O/c1-15-5-2-3-6-17(15)22-20(25)24-13-11-23(12-14-24)19-8-4-7-18-16(19)9-10-21-18/h2-10,21H,11-14H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462474 (CHEMBL4242890) Show SMILES FC(F)(F)c1cccc(NC(=O)N2CCN(CC2)c2ccncc2)c1 Show InChI InChI=1S/C17H17F3N4O/c18-17(19,20)13-2-1-3-14(12-13)22-16(25)24-10-8-23(9-11-24)15-4-6-21-7-5-15/h1-7,12H,8-11H2,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462475 (CHEMBL4249657) Show SMILES COc1ccccc1N1CCN(CC1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C18H21N3O2/c1-23-17-10-6-5-9-16(17)20-11-13-21(14-12-20)18(22)19-15-7-3-2-4-8-15/h2-10H,11-14H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462476 (CHEMBL4244692) Show SMILES CC(C)N1CCN(CC1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C14H21N3O/c1-12(2)16-8-10-17(11-9-16)14(18)15-13-6-4-3-5-7-13/h3-7,12H,8-11H2,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462478 (CHEMBL4239952) Show SMILES Cc1ccc2[nH]ccc2c1N1CCN(CC1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C20H22N4O/c1-15-7-8-18-17(9-10-21-18)19(15)23-11-13-24(14-12-23)20(25)22-16-5-3-2-4-6-16/h2-10,21H,11-14H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair
Aspartate aminotransferase, cytoplasmic (Homo sapiens)	BDBM50462479 (CHEMBL4239480) Show SMILES O=C(OCc1ccccc1)N1CCN(CC1)c1cccc2[nH]ccc12 Show InChI InChI=1S/C20H21N3O2/c24-20(25-15-16-5-2-1-3-6-16)23-13-11-22(12-14-23)19-8-4-7-18-17(19)9-10-21-18/h1-10,21H,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
California Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay				Bioorg Med Chem Lett 28: 2675-2678 (2018) Article DOI: 10.1016/j.bmcl.2018.04.061 BindingDB Entry DOI: 10.7270/Q2MC92P6
					More data for this Ligand-Target Pair

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