Found 26 hits of ic50 for UniProtKB: P54283 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481859
(CHEMBL1088309)Show SMILES O=C(CCCCC(c1ccccc1)c1ccccc1)N1CCN(C\C=C\c2ccccc2)CC1 Show InChI InChI=1S/C31H36N2O/c34-31(33-25-23-32(24-26-33)22-12-15-27-13-4-1-5-14-27)21-11-10-20-30(28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-9,12-19,30H,10-11,20-26H2/b15-12+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481859
(CHEMBL1088309)Show SMILES O=C(CCCCC(c1ccccc1)c1ccccc1)N1CCN(C\C=C\c2ccccc2)CC1 Show InChI InChI=1S/C31H36N2O/c34-31(33-25-23-32(24-26-33)22-12-15-27-13-4-1-5-14-27)21-11-10-20-30(28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-9,12-19,30H,10-11,20-26H2/b15-12+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50017702
(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)Show SMILES Fc1ccc(cc1)C(N1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H26F2N2/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21/h1-15,26H,16-20H2/b7-4+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481860
(CHEMBL1087660)Show SMILES Fc1ccc(cc1)C(CCCCC(=O)N1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C31H34F2N2O/c32-28-16-12-26(13-17-28)30(27-14-18-29(33)19-15-27)10-4-5-11-31(36)35-23-21-34(22-24-35)20-6-9-25-7-2-1-3-8-25/h1-3,6-9,12-19,30H,4-5,10-11,20-24H2/b9-6+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50095765
(1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)m...)Show SMILES COc1ccc(CN2CCN(CC2)C(c2ccc(F)cc2)c2ccc(F)cc2)c(OC)c1OC Show InChI InChI=1S/C27H30F2N2O3/c1-32-24-13-8-21(26(33-2)27(24)34-3)18-30-14-16-31(17-15-30)25(19-4-9-22(28)10-5-19)20-6-11-23(29)12-7-20/h4-13,25H,14-18H2,1-3H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481862
(CHEMBL1087275)Show SMILES COc1ccc(\C=C\C(=O)N2CCN(CC2)C(=O)CCCCC(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C32H36N2O3/c1-37-29-19-16-26(17-20-29)18-21-32(36)34-24-22-33(23-25-34)31(35)15-9-8-14-30(27-10-4-2-5-11-27)28-12-6-3-7-13-28/h2-7,10-13,16-21,30H,8-9,14-15,22-25H2,1H3/b21-18+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50461289
(MK-6721 | NMED-160 | NP-118809 | Z-160 | Z160)Show SMILES O=C(CC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H32N2O/c35-31(25-30(26-13-5-1-6-14-26)27-15-7-2-8-16-27)33-21-23-34(24-22-33)32(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20,30,32H,21-25H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481858
(CHEMBL1086621)Show SMILES COc1cc(cc(OC)c1OC)C(=O)N1CCN(CCCCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C32H38F2N2O4/c1-38-29-21-25(22-30(39-2)31(29)40-3)32(37)36-19-17-35(18-20-36)16-6-4-5-7-28(23-8-12-26(33)13-9-23)24-10-14-27(34)15-11-24/h8-15,21-22,28H,4-7,16-20H2,1-3H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481868
(CHEMBL1088610)Show SMILES O=C(CCCCC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(=O)\C=C\c1cccc2OCOc12 Show InChI InChI=1S/C32H34N2O4/c35-30(17-8-7-15-28(25-10-3-1-4-11-25)26-12-5-2-6-13-26)33-20-22-34(23-21-33)31(36)19-18-27-14-9-16-29-32(27)38-24-37-29/h1-6,9-14,16,18-19,28H,7-8,15,17,20-24H2/b19-18+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481864
(CHEMBL1087237)Show SMILES Nc1ccc(\C=C\C(=O)N2CCN(CC2)C(=O)CCCCC(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C31H35N3O2/c32-28-18-15-25(16-19-28)17-20-31(36)34-23-21-33(22-24-34)30(35)14-8-7-13-29(26-9-3-1-4-10-26)27-11-5-2-6-12-27/h1-6,9-12,15-20,29H,7-8,13-14,21-24,32H2/b20-17+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481466
(CHEMBL599217)Show SMILES O=C(NC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H31N3O/c35-31(32-29(25-13-5-1-6-14-25)26-15-7-2-8-16-26)34-23-21-33(22-24-34)30(27-17-9-3-10-18-27)28-19-11-4-12-20-28/h1-20,29-30H,21-24H2,(H,32,35) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481869
(CHEMBL1088308)Show SMILES COc1cc(CN2CCN(CC2)C(=O)CCCCC(c2ccc(F)cc2)c2ccc(F)cc2)cc(OC)c1OC Show InChI InChI=1S/C32H38F2N2O4/c1-38-29-20-23(21-30(39-2)32(29)40-3)22-35-16-18-36(19-17-35)31(37)7-5-4-6-28(24-8-12-26(33)13-9-24)25-10-14-27(34)15-11-25/h8-15,20-21,28H,4-7,16-19,22H2,1-3H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481863
(CHEMBL1088464)Show SMILES O=C(CCCCC(c1ccccc1)c1ccccc1)N1CCN(C\C=C\c2cccc3OCOc23)CC1 Show InChI InChI=1S/C32H36N2O3/c35-31(19-8-7-17-29(26-11-3-1-4-12-26)27-13-5-2-6-14-27)34-23-21-33(22-24-34)20-10-16-28-15-9-18-30-32(28)37-25-36-30/h1-6,9-16,18,29H,7-8,17,19-25H2/b16-10+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481861
(CHEMBL1087779)Show SMILES COc1ccc(\C=C\CN2CCN(CC2)C(=O)CCCCC(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C32H38N2O2/c1-36-30-20-18-27(19-21-30)11-10-22-33-23-25-34(26-24-33)32(35)17-9-8-16-31(28-12-4-2-5-13-28)29-14-6-3-7-15-29/h2-7,10-15,18-21,31H,8-9,16-17,22-26H2,1H3/b11-10+ | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481449
(CHEMBL599408)Show SMILES O=C(CN1CCN(CC1)C(c1ccccc1)c1ccccc1)N(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H31N3O/c35-30(34(28-17-9-3-10-18-28)29-19-11-4-12-20-29)25-32-21-23-33(24-22-32)31(26-13-5-1-6-14-26)27-15-7-2-8-16-27/h1-20,31H,21-25H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481867
(CHEMBL1088174)Show SMILES COc1cc(cc(OC)c1OC)C(=O)N1CCN(CC1)C(=O)CCCCC(c1ccc(F)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C32H36F2N2O5/c1-39-28-20-24(21-29(40-2)31(28)41-3)32(38)36-18-16-35(17-19-36)30(37)7-5-4-6-27(22-8-12-25(33)13-9-22)23-10-14-26(34)15-11-23/h8-15,20-21,27H,4-7,16-19H2,1-3H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481853
(CHEMBL1081018)Show SMILES C(CN1CCN(CC1)C(c1ccccc1)c1ccccc1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H34N2/c1-5-13-27(14-6-1)31(28-15-7-2-8-16-28)21-22-33-23-25-34(26-24-33)32(29-17-9-3-10-18-29)30-19-11-4-12-20-30/h1-20,31-32H,21-26H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481854
(CHEMBL1081016)Show SMILES C(CC(c1ccccc1)c1ccccc1)CN1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H36N2/c1-5-14-28(15-6-1)32(29-16-7-2-8-17-29)22-13-23-34-24-26-35(27-25-34)33(30-18-9-3-10-19-30)31-20-11-4-12-21-31/h1-12,14-21,32-33H,13,22-27H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481453
(CHEMBL597148)Show SMILES O=C(CN(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H31N3O/c35-30(25-34(28-17-9-3-10-18-28)29-19-11-4-12-20-29)32-21-23-33(24-22-32)31(26-13-5-1-6-14-26)27-15-7-2-8-16-27/h1-20,31H,21-25H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481865
(CHEMBL1081175)Show SMILES C(CCN1CCN(CC1)C(c1ccccc1)c1ccccc1)CC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C34H38N2/c1-5-15-29(16-6-1)33(30-17-7-2-8-18-30)23-13-14-24-35-25-27-36(28-26-35)34(31-19-9-3-10-20-31)32-21-11-4-12-22-32/h1-12,15-22,33-34H,13-14,23-28H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481866
(CHEMBL1081365)Show SMILES O=C(CCC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H34N2O/c36-32(22-21-31(27-13-5-1-6-14-27)28-15-7-2-8-16-28)34-23-25-35(26-24-34)33(29-17-9-3-10-18-29)30-19-11-4-12-20-30/h1-20,31,33H,21-26H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481870
(CHEMBL1081177)Show SMILES O=C(C(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H30N2O/c34-31(29(25-13-5-1-6-14-25)26-15-7-2-8-16-26)33-23-21-32(22-24-33)30(27-17-9-3-10-18-27)28-19-11-4-12-20-28/h1-20,29-30H,21-24H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481857
(CHEMBL1080461)Show SMILES O=C(CCCCC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C35H38N2O/c38-34(24-14-13-23-33(29-15-5-1-6-16-29)30-17-7-2-8-18-30)36-25-27-37(28-26-36)35(31-19-9-3-10-20-31)32-21-11-4-12-22-32/h1-12,15-22,33,35H,13-14,23-28H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481856
(CHEMBL1081366)Show SMILES O=C(CCCC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C34H36N2O/c37-33(23-13-22-32(28-14-5-1-6-15-28)29-16-7-2-8-17-29)35-24-26-36(27-25-35)34(30-18-9-3-10-19-30)31-20-11-4-12-21-31/h1-12,14-21,32,34H,13,22-27H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481855
(CHEMBL1081176)Show SMILES C(CCC(c1ccccc1)c1ccccc1)CCN1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C35H40N2/c1-6-16-30(17-7-1)34(31-18-8-2-9-19-31)24-14-5-15-25-36-26-28-37(29-27-36)35(32-20-10-3-11-21-32)33-22-12-4-13-23-33/h1-4,6-13,16-23,34-35H,5,14-15,24-29H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1
(Rattus norvegicus-Rattus norvegicus (Rat)) | BDBM50481852
(CHEMBL1080654)Show SMILES C(C(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H32N2/c1-5-13-26(14-6-1)30(27-15-7-2-8-16-27)25-32-21-23-33(24-22-32)31(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20,30-31H,21-25H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calgary
Curated by ChEMBL
| Assay Description
Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce... |
Bioorg Med Chem Lett 19: 6467-72 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.008
BindingDB Entry DOI: 10.7270/Q2PV6P57 |
More data for this
Ligand-Target Pair | |
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