Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM372992 (US10597366, Compound 64 | US9896418, Compound 64) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM372992 (US10597366, Compound 64 | US9896418, Compound 64) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM372992 (US10597366, Compound 64 | US9896418, Compound 64) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM566629 (3-fluoro-5-(((1R,2S,2aS)-1,2,3,3,4,4-hexafluoro- 2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were... | Citation and Details BindingDB Entry DOI: 10.7270/Q2474F3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373015 (US10597366, Compound 185 | US9896418, Compound 185) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373015 (US10597366, Compound 185 | US9896418, Compound 185) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373015 (US10597366, Compound 185 | US9896418, Compound 185) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373004 (US10597366, Compound 158 | US9896418, Compound 158) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373004 (US10597366, Compound 158 | US9896418, Compound 158) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM372966 (US10597366, Compound 9 | US9896418, Compound 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM372966 (US10597366, Compound 9 | US9896418, Compound 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373004 (US10597366, Compound 158 | US9896418, Compound 158) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM566616 (3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a- hy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were... | Citation and Details BindingDB Entry DOI: 10.7270/Q2474F3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM566616 (3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a- hy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were... | Citation and Details BindingDB Entry DOI: 10.7270/Q2474F3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM372966 (US10597366, Compound 9 | US9896418, Compound 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373041 (US10597366, Compound 292 | US9896418, Compound 292) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373042 (US10597366, Compound 273 | US9896418, Compound 273) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373041 (US10597366, Compound 292 | US9896418, Compound 292) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373042 (US10597366, Compound 273 | US9896418, Compound 273) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373041 (US10597366, Compound 292 | US9896418, Compound 292) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373042 (US10597366, Compound 273 | US9896418, Compound 273) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM566628 ((R)-3-fluoro-5-((3,3,4,4-tetrafluoro-2a-hydroxy-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were... | Citation and Details BindingDB Entry DOI: 10.7270/Q2474F3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373005 (US10597366, Compound 159 | US9896418, Compound 159) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373005 (US10597366, Compound 159 | US9896418, Compound 159) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373005 (US10597366, Compound 159 | US9896418, Compound 159) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM282572 ((R)-3-((4-(difluoromethyl)-2,2-difluoro-3-hydroxy-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a |
PELOTON THERAPEUTICS, INC. US Patent | Assay Description About 7500 of 786-O cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | US Patent US9884843 (2018) BindingDB Entry DOI: 10.7270/Q2HQ41Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM282656 (4-(Difluoromethyl)-5-(3,5-difluorophenoxy)-2,2- di...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a |
PELOTON THERAPEUTICS, INC. US Patent | Assay Description About 7500 of 786-O cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | US Patent US9884843 (2018) BindingDB Entry DOI: 10.7270/Q2HQ41Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM566615 (3-fluoro-5-((1,3,3,4,4-pentafluoro-2a-hydroxy- 2,2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were... | Citation and Details BindingDB Entry DOI: 10.7270/Q2474F3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM566630 (3-fluoro-5-(((1R,2R,2aS)-1,2,3,3,4,4-hexafluoro- 2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were... | Citation and Details BindingDB Entry DOI: 10.7270/Q2474F3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373006 (US10597366, Compound 161 | US9896418, Compound 161) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373006 (US10597366, Compound 161 | US9896418, Compound 161) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373006 (US10597366, Compound 161 | US9896418, Compound 161) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM566614 (3-fluoro-5-((3,3,4,4-tetrafluoro-2a-hydroxy-1- met...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were... | Citation and Details BindingDB Entry DOI: 10.7270/Q2474F3H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373016 (US10597366, Compound 186 | US9896418, Compound 186) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM372976 (US10597366, Compound 15 | US9896418, Compound 15) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM372976 (US10597366, Compound 15 | US9896418, Compound 15) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM372976 (US10597366, Compound 15 | US9896418, Compound 15) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373016 (US10597366, Compound 186 | US9896418, Compound 186) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373016 (US10597366, Compound 186 | US9896418, Compound 186) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM438062 (US10597366, Compound 317 | US10597366, Compound 32...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373050 (US10597366, Compound 316 | US9896418, Compound 316...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM282685 (3-((4-(Difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
PELOTON THERAPEUTICS, INC. US Patent | Assay Description About 7500 of 786-O cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | US Patent US9884843 (2018) BindingDB Entry DOI: 10.7270/Q2HQ41Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373050 (US10597366, Compound 316 | US9896418, Compound 316...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373028 (US10597366, Compound 233 | US9896418, Compound 233) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM372972 (US10597366, Compound 11 | US9896418, Compound 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM372972 (US10597366, Compound 11 | US9896418, Compound 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM372972 (US10597366, Compound 11 | US9896418, Compound 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373028 (US10597366, Compound 233 | US9896418, Compound 233) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
Research Triangle Institute | Assay Description Four hours later, serial dilutions of 10× compound stocks were made in growth medium from 500×DMSO stocks, and 20 μL of those 10× stocks were ad... | J Med Chem 50: 3686-95 (2007) BindingDB Entry DOI: 10.7270/Q2QC05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373028 (US10597366, Compound 233 | US9896418, Compound 233) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
Peloton Therapeutics, Inc. US Patent | Assay Description VEGF: Four hours later, serial dilutions of 10x compound stocks were made in growth medium from 500xDMSO stocks, and 20 uL of those 10x stocks were a... | US Patent US10597366 (2020) BindingDB Entry DOI: 10.7270/Q2M32ZSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor A (Homo sapiens (Human)) | BDBM373031 (US10597366, Compound 236 | US9896418, Compound 236) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
The Scripps Research Institute | Assay Description About 7500 of 786-0 cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-... | J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q2FN18HM | |||||||||||
More data for this Ligand-Target Pair |
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