Compile Data Set for Download or QSAR

Found 1014 hits of ec50 for UniProtKB: P04628   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293564 (US10106527, Compound 275 | US10544128, Compound 27...) Show SMILES CC(C)N1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cncn1C Show InChI InChI=1S/C26H29N7O/c1-18(2)32-8-10-33(11-9-32)25-14-20(6-7-28-25)26(34)30-24-13-22-12-19(4-5-21(22)15-29-24)23-16-27-17-31(23)3/h4-7,12-18H,8-11H2,1-3H3,(H,29,30,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293600 (US10106527, Compound 359 | US10544128, Compound 35...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnc(N)s1 Show InChI InChI=1S/C23H23N7OS/c1-29-6-8-30(9-7-29)21-12-16(4-5-25-21)22(31)28-20-11-18-10-15(2-3-17(18)13-26-20)19-14-27-23(24)32-19/h2-5,10-14H,6-9H2,1H3,(H2,24,27)(H,26,28,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293546 (US10106527, Compound 238 | US10544128, Compound 23...) Show SMILES CN1CCC(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn(C)nn1 Show InChI InChI=1S/C24H25N7O/c1-30-9-6-16(7-10-30)21-12-18(5-8-25-21)24(32)27-23-13-20-11-17(3-4-19(20)14-26-23)22-15-31(2)29-28-22/h3-5,8,11-16H,6-7,9-10H2,1-2H3,(H,26,27,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293536 (US10106527, Compound 204 | US10544128, Compound 20...) Show SMILES Cn1ncc(c1CN1CCOCC1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCOCC3)cc2c1 Show InChI InChI=1S/C28H31N7O3/c1-33-25(19-34-6-10-37-11-7-34)24(18-31-33)20-2-3-22-17-30-26(15-23(22)14-20)32-28(36)21-4-5-29-27(16-21)35-8-12-38-13-9-35/h2-5,14-18H,6-13,19H2,1H3,(H,30,32,36)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293453 (US10106527, Compound 56 | US10544128, Compound 56 ...) Show SMILES CC(C)N1CCC(CC1)Oc1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C27H30N6O2/c1-18(2)33-10-7-24(8-11-33)35-26-14-20(6-9-28-26)27(34)31-25-13-22-12-19(4-5-21(22)15-29-25)23-16-30-32(3)17-23/h4-6,9,12-18,24H,7-8,10-11H2,1-3H3,(H,29,31,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293452 (US10106527, Compound 55 | US10544128, Compound 55 ...) Show SMILES CN(C)C1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C26H29N7O/c1-31(2)23-7-10-33(11-8-23)25-14-19(6-9-27-25)26(34)30-24-13-21-12-18(4-5-20(21)15-28-24)22-16-29-32(3)17-22/h4-6,9,12-17,23H,7-8,10-11H2,1-3H3,(H,28,30,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293444 (US10106527, Compound 37 | US10544128, Compound 37 ...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cncn1C Show InChI InChI=1S/C24H25N7O/c1-29-7-9-31(10-8-29)23-13-18(5-6-26-23)24(32)28-22-12-20-11-17(3-4-19(20)14-27-22)21-15-25-16-30(21)2/h3-6,11-16H,7-10H2,1-2H3,(H,27,28,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293471 (US10106527, Compound 85 | US10544128, Compound 85 ...) Show SMILES CN1CCC(=CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 |c:4| Show InChI InChI=1S/C25H24N6O/c1-30-9-6-17(7-10-30)23-12-19(5-8-26-23)25(32)29-24-13-21-11-18(3-4-20(21)14-27-24)22-15-28-31(2)16-22/h3-6,8,11-16H,7,9-10H2,1-2H3,(H,27,29,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293451 (US10106527, Compound 54 | US10544128, Compound 54 ...) Show SMILES CNC1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C25H27N7O/c1-26-22-6-9-32(10-7-22)24-13-18(5-8-27-24)25(33)30-23-12-20-11-17(3-4-19(20)14-28-23)21-15-29-31(2)16-21/h3-5,8,11-16,22,26H,6-7,9-10H2,1-2H3,(H,28,30,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293547 (US10106527, Compound 240 | US10544128, Compound 24...) Show SMILES CN(C)C1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn(C)nn1 Show InChI InChI=1S/C25H28N8O/c1-31(2)21-7-10-33(11-8-21)24-14-18(6-9-26-24)25(34)28-23-13-20-12-17(4-5-19(20)15-27-23)22-16-32(3)30-29-22/h4-6,9,12-16,21H,7-8,10-11H2,1-3H3,(H,27,28,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293632 (US10106527, Compound 430 | US10544128, Compound 43...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1nnc(N)s1 Show InChI InChI=1S/C22H22N8OS/c1-29-6-8-30(9-7-29)19-12-14(4-5-24-19)20(31)26-18-11-17-10-15(2-3-16(17)13-25-18)21-27-28-22(23)32-21/h2-5,10-13H,6-9H2,1H3,(H2,23,28)(H,25,26,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293546 (US10106527, Compound 238 | US10544128, Compound 23...) Show SMILES CN1CCC(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn(C)nn1 Show InChI InChI=1S/C24H25N7O/c1-30-9-6-16(7-10-30)21-12-18(5-8-25-21)24(32)27-23-13-20-11-17(3-4-19(20)14-26-23)22-15-31(2)29-28-22/h3-5,8,11-16H,6-7,9-10H2,1-2H3,(H,26,27,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293479 (US10106527, Compound 93 | US10544128, Compound 93 ...) Show SMILES CN1CCC2(CN(C2)c2cc(ccn2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C27H29N7O/c1-32-9-6-27(7-10-32)17-34(18-27)25-13-20(5-8-28-25)26(35)31-24-12-22-11-19(3-4-21(22)14-29-24)23-15-30-33(2)16-23/h3-5,8,11-16H,6-7,9-10,17-18H2,1-2H3,(H,29,31,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293542 (US10106527, Compound 230 | US10544128, Compound 23...) Show SMILES CN1CCC(CC1)Oc1cccc(c1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn(C)nn1 Show InChI InChI=1S/C25H26N6O2/c1-30-10-8-21(9-11-30)33-22-5-3-4-18(13-22)25(32)27-24-14-20-12-17(6-7-19(20)15-26-24)23-16-31(2)29-28-23/h3-7,12-16,21H,8-11H2,1-2H3,(H,26,27,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293551 (US10106527, Compound 245 | US10544128, Compound 24...) Show SMILES CC(C)N1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn(C)nn1 Show InChI InChI=1S/C25H28N8O/c1-17(2)32-8-10-33(11-9-32)24-14-19(6-7-26-24)25(34)28-23-13-21-12-18(4-5-20(21)15-27-23)22-16-31(3)30-29-22/h4-7,12-17H,8-11H2,1-3H3,(H,27,28,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293415 (US10106527, Compound 1 | US10106527, Compound 145 ...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn[nH]c1 Show InChI InChI=1S/C23H23N7O/c1-29-6-8-30(9-7-29)22-12-17(4-5-24-22)23(31)28-21-11-19-10-16(20-14-26-27-15-20)2-3-18(19)13-25-21/h2-5,10-15H,6-9H2,1H3,(H,26,27)(H,25,28,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293423 (US10106527, Compound 461 | US10106527, Compound 9 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCNCC3)cc2c1 Show InChI InChI=1S/C23H23N7O/c1-29-15-20(14-27-29)16-2-3-18-13-26-21(11-19(18)10-16)28-23(31)17-4-5-25-22(12-17)30-8-6-24-7-9-30/h2-5,10-15,24H,6-9H2,1H3,(H,26,28,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293450 (US10106527, Compound 53 | US10544128, Compound 53 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCC(N)CC3)cc2c1 Show InChI InChI=1S/C24H25N7O/c1-30-15-20(14-28-30)16-2-3-18-13-27-22(11-19(18)10-16)29-24(32)17-4-7-26-23(12-17)31-8-5-21(25)6-9-31/h2-4,7,10-15,21H,5-6,8-9,25H2,1H3,(H,27,29,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293628 (US10106527, Compound 423 | US10544128, Compound 42...) Show SMILES CN1CCC(CC1)Sc1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1nnc(C)s1 Show InChI InChI=1S/C24H24N6OS2/c1-15-28-29-24(32-15)17-3-4-18-14-26-21(12-19(18)11-17)27-23(31)16-5-8-25-22(13-16)33-20-6-9-30(2)10-7-20/h3-5,8,11-14,20H,6-7,9-10H2,1-2H3,(H,26,27,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293483 (US10106527, Compound 99 | US10544128, Compound 99 ...) Show SMILES CN1CCC(CC1)Sc1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C25H26N6OS/c1-30-9-6-22(7-10-30)33-24-13-18(5-8-26-24)25(32)29-23-12-20-11-17(3-4-19(20)14-27-23)21-15-28-31(2)16-21/h3-5,8,11-16,22H,6-7,9-10H2,1-2H3,(H,27,29,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	41	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293482 (US10106527, Compound 97 | US10544128, Compound 97 ...) Show SMILES CN(C1CCN(C)CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C26H29N7O/c1-31-10-7-23(8-11-31)33(3)25-14-19(6-9-27-25)26(34)30-24-13-21-12-18(4-5-20(21)15-28-24)22-16-29-32(2)17-22/h4-6,9,12-17,23H,7-8,10-11H2,1-3H3,(H,28,30,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	41	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293623 (US10106527, Compound 409 | US10544128, Compound 40...) Show SMILES CN1CCC(=CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1nnc(C)s1 |c:4| Show InChI InChI=1S/C24H22N6OS/c1-15-28-29-24(32-15)18-3-4-19-14-26-22(13-20(19)11-18)27-23(31)17-5-8-25-21(12-17)16-6-9-30(2)10-7-16/h3-6,8,11-14H,7,9-10H2,1-2H3,(H,26,27,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	41	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293549 (US10106527, Compound 242 | US10106527, Compound 43...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn(C)nn1 Show InChI InChI=1S/C23H24N8O/c1-29-7-9-31(10-8-29)22-13-17(5-6-24-22)23(32)26-21-12-19-11-16(3-4-18(19)14-25-21)20-15-30(2)28-27-20/h3-6,11-15H,7-10H2,1-2H3,(H,25,26,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293619 (US10106527, Compound 391 | US10544128, Compound 39...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1nncs1 Show InChI InChI=1S/C22H21N7OS/c1-28-6-8-29(9-7-28)20-12-15(4-5-23-20)21(30)26-19-11-18-10-16(22-27-25-14-31-22)2-3-17(18)13-24-19/h2-5,10-14H,6-9H2,1H3,(H,24,26,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293423 (US10106527, Compound 461 | US10106527, Compound 9 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCNCC3)cc2c1 Show InChI InChI=1S/C23H23N7O/c1-29-15-20(14-27-29)16-2-3-18-13-26-21(11-19(18)10-16)28-23(31)17-4-5-25-22(12-17)30-8-6-24-7-9-30/h2-5,10-15,24H,6-9H2,1H3,(H,26,28,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293464 (BDBM427096 | US10106527, Compound 71 | US11548872,...) Show SMILES CN(C)Cc1ccc(cc1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C23H23N5O/c1-27(2)14-16-4-6-17(7-5-16)23(29)26-22-11-20-10-18(8-9-19(20)12-24-22)21-13-25-28(3)15-21/h4-13,15H,14H2,1-3H3,(H,24,26,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293424 (US10106527, Compound 10 | US10106527, Compound 142...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C24H25N7O/c1-29-7-9-31(10-8-29)23-13-18(5-6-25-23)24(32)28-22-12-20-11-17(3-4-19(20)14-26-22)21-15-27-30(2)16-21/h3-6,11-16H,7-10H2,1-2H3,(H,26,28,32)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293424 (US10106527, Compound 10 | US10106527, Compound 142...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C24H25N7O/c1-29-7-9-31(10-8-29)23-13-18(5-6-25-23)24(32)28-22-12-20-11-17(3-4-19(20)14-26-22)21-15-27-30(2)16-21/h3-6,11-16H,7-10H2,1-2H3,(H,26,28,32)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM427094 (US10544128, Compound 66) Show SMILES CN1CC(C1)Oc1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn(C)nn1 Show InChI InChI=1S/C22H21N7O2/c1-28-11-18(12-28)31-21-9-15(5-6-23-21)22(30)25-20-8-17-7-14(3-4-16(17)10-24-20)19-13-29(2)27-26-19/h3-10,13,18H,11-12H2,1-2H3,(H,24,25,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293527 (US10106527, Compound 149 | US10544128, Compound 14...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1N Show InChI InChI=1S/C24H26N8O/c1-30-7-9-32(10-8-30)22-13-17(5-6-26-22)24(33)29-21-12-19-11-16(3-4-18(19)14-27-21)20-15-28-31(2)23(20)25/h3-6,11-15H,7-10,25H2,1-2H3,(H,27,29,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293633 (US10106527, Compound 431 | US10544128, Compound 43...) Show SMILES Cn1cc(nn1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCNCC3)cc2c1 Show InChI InChI=1S/C22H22N8O/c1-29-14-19(27-28-29)15-2-3-17-13-25-20(11-18(17)10-15)26-22(31)16-4-5-24-21(12-16)30-8-6-23-7-9-30/h2-5,10-14,23H,6-9H2,1H3,(H,25,26,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293549 (US10106527, Compound 242 | US10106527, Compound 43...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn(C)nn1 Show InChI InChI=1S/C23H24N8O/c1-29-7-9-31(10-8-29)22-13-17(5-6-24-22)23(32)26-21-12-19-11-16(3-4-18(19)14-25-21)20-15-30(2)28-27-20/h3-6,11-15H,7-10H2,1-2H3,(H,25,26,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293424 (US10106527, Compound 10 | US10106527, Compound 142...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C24H25N7O/c1-29-7-9-31(10-8-29)23-13-18(5-6-25-23)24(32)28-22-12-20-11-17(3-4-19(20)14-26-22)21-15-27-30(2)16-21/h3-6,11-16H,7-10H2,1-2H3,(H,26,28,32)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293466 (US10106527, Compound 74 | US10544128, Compound 74 ...) Show SMILES CN1CCN(Cc2cccc(c2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C26H28N6O/c1-30-8-10-32(11-9-30)17-19-4-3-5-21(12-19)26(33)29-25-14-23-13-20(6-7-22(23)15-27-25)24-16-28-31(2)18-24/h3-7,12-16,18H,8-11,17H2,1-2H3,(H,27,29,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293554 (US10106527, Compound 253 | US10544128, Compound 25...) Show SMILES CN1CCC(CC1)Sc1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn(C)nn1 Show InChI InChI=1S/C24H25N7OS/c1-30-9-6-20(7-10-30)33-23-13-17(5-8-25-23)24(32)27-22-12-19-11-16(3-4-18(19)14-26-22)21-15-31(2)29-28-21/h3-5,8,11-15,20H,6-7,9-10H2,1-2H3,(H,26,27,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293424 (US10106527, Compound 10 | US10106527, Compound 142...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C24H25N7O/c1-29-7-9-31(10-8-29)23-13-18(5-6-25-23)24(32)28-22-12-20-11-17(3-4-19(20)14-26-22)21-15-27-30(2)16-21/h3-6,11-16H,7-10H2,1-2H3,(H,26,28,32)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293553 (US10106527, Compound 250 | US10544128, Compound 25...) Show SMILES CN(C1CCN(C)CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn(C)nn1 Show InChI InChI=1S/C25H28N8O/c1-31-10-7-21(8-11-31)33(3)24-14-18(6-9-26-24)25(34)28-23-13-20-12-17(4-5-19(20)15-27-23)22-16-32(2)30-29-22/h4-6,9,12-16,21H,7-8,10-11H2,1-3H3,(H,27,28,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293424 (US10106527, Compound 10 | US10106527, Compound 142...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C24H25N7O/c1-29-7-9-31(10-8-29)23-13-18(5-6-25-23)24(32)28-22-12-20-11-17(3-4-19(20)14-26-22)21-15-27-30(2)16-21/h3-6,11-16H,7-10H2,1-2H3,(H,26,28,32)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293597 (US10106527, Compound 338 | US10544128, Compound 33...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cncs1 Show InChI InChI=1S/C23H22N6OS/c1-28-6-8-29(9-7-28)22-12-17(4-5-25-22)23(30)27-21-11-19-10-16(20-14-24-15-31-20)2-3-18(19)13-26-21/h2-5,10-15H,6-9H2,1H3,(H,26,27,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293560 (US10106527, Compound 266 | US10544128, Compound 26...) Show SMILES Cn1cncc1-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CC(N)C3)cc2c1 Show InChI InChI=1S/C22H21N7O/c1-28-13-24-10-19(28)14-2-3-16-9-26-20(7-17(16)6-14)27-22(30)15-4-5-25-21(8-15)29-11-18(23)12-29/h2-10,13,18H,11-12,23H2,1H3,(H,26,27,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293463 (US10106527, Compound 67 | US10544128, Compound 67 ...) Show SMILES CCN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C25H27N7O/c1-3-31-8-10-32(11-9-31)24-14-19(6-7-26-24)25(33)29-23-13-21-12-18(4-5-20(21)15-27-23)22-16-28-30(2)17-22/h4-7,12-17H,3,8-11H2,1-2H3,(H,27,29,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293431 (US10106527, Compound 17 | US10544128, Compound 17 ...) Show SMILES CN1CCC(CC1)Oc1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C25H26N6O2/c1-30-9-6-22(7-10-30)33-24-13-18(5-8-26-24)25(32)29-23-12-20-11-17(3-4-19(20)14-27-23)21-15-28-31(2)16-21/h3-5,8,11-16,22H,6-7,9-10H2,1-2H3,(H,27,29,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	58	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293512 (US10106527, Compound 134 | US10544128, Compound 13...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(-c3cnn(C)c3)c(F)cc2cn1 Show InChI InChI=1S/C24H24FN7O/c1-30-5-7-32(8-6-30)23-12-16(3-4-26-23)24(33)29-22-11-17-9-20(19-14-28-31(2)15-19)21(25)10-18(17)13-27-22/h3-4,9-15H,5-8H2,1-2H3,(H,27,29,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	58	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293624 (US10106527, Compound 412 | US10544128, Compound 42...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1nnc(C)s1 Show InChI InChI=1S/C23H23N7OS/c1-15-27-28-23(32-15)17-3-4-18-14-25-20(12-19(18)11-17)26-22(31)16-5-6-24-21(13-16)30-9-7-29(2)8-10-30/h3-6,11-14H,7-10H2,1-2H3,(H,25,26,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293595 (US10106527, Compound 336 | US10544128, Compound 33...) Show SMILES CN(C)C1CN(C1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cncs1 Show InChI InChI=1S/C23H22N6OS/c1-28(2)19-12-29(13-19)22-9-16(5-6-25-22)23(30)27-21-8-18-7-15(20-11-24-14-31-20)3-4-17(18)10-26-21/h3-11,14,19H,12-13H2,1-2H3,(H,26,27,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM427097 (US10544128, Compound 72) Show SMILES CN1CCC(CC1)c1cccc(c1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn(C)nn1 Show InChI InChI=1S/C25H26N6O/c1-30-10-8-17(9-11-30)18-4-3-5-20(12-18)25(32)27-24-14-22-13-19(6-7-21(22)15-26-24)23-16-31(2)29-28-23/h3-7,12-17H,8-11H2,1-2H3,(H,26,27,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293455 (US10106527, Compound 59 | US10544128, Compound 59 ...) Show SMILES CN(C)C1CN(C1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C24H25N7O/c1-29(2)21-14-31(15-21)23-10-17(6-7-25-23)24(32)28-22-9-19-8-16(4-5-18(19)11-26-22)20-12-27-30(3)13-20/h4-13,21H,14-15H2,1-3H3,(H,26,28,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293430 (US10106527, Compound 16 | US10544128, Compound 16 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccnc(OC4CCNCC4)c3)cc2c1 Show InChI InChI=1S/C24H24N6O2/c1-30-15-20(14-28-30)16-2-3-18-13-27-22(11-19(18)10-16)29-24(31)17-4-9-26-23(12-17)32-21-5-7-25-8-6-21/h2-4,9-15,21,25H,5-8H2,1H3,(H,27,29,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293433 (US10106527, Compound 19 | US10544128, Compound 19 ...) Show SMILES CN1CCC(CC1)Nc1cncc(c1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C25H27N7O/c1-31-7-5-22(6-8-31)29-23-10-20(12-26-15-23)25(33)30-24-11-19-9-17(3-4-18(19)13-27-24)21-14-28-32(2)16-21/h3-4,9-16,22,29H,5-8H2,1-2H3,(H,27,30,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	66	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM293415 (US10106527, Compound 1 | US10106527, Compound 145 ...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn[nH]c1 Show InChI InChI=1S/C23H23N7O/c1-29-6-8-30(9-7-29)22-12-17(4-5-24-22)23(31)28-21-11-19-10-16(20-14-26-27-15-20)2-3-18(19)13-25-21/h2-5,10-15H,6-9H2,1H3,(H,26,27)(H,25,28,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair

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