Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112632 (Euonyquinone A (5)) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112633 (Combrequinone B (6)) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.16E+4 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112634 (Euonyquinone B (7)) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112629 (Euonydiarylpropane B (2)) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112628 (Euonydiarylpropane A (1)) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112635 ((−)-Euonyquinone C (8) | (+)-Euonyquinone C ...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112635 ((−)-Euonyquinone C (8) | (+)-Euonyquinone C ...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112639 (1-(2-hydroxy-4-meth-oxyphenyl)-3-(4-hydroxy-3-meth...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112640 ((2R)-3′,4′-Dihydroxy-7-methoxyflavan (...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112637 (Griffithane B (10)) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112638 (Broussonin F (11)) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112641 ((2R)-3′,4′-Dihydroxy-5,7-methoxyflavan...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112630 (Euonydiarylpropane C (3)) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM112631 (Euonydiarylpropane D (4)) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a (Homo sapiens (Human)) | BDBM48449 (3-(3,4-DIHYDROXYPHENYL)-2-METHYL-L-ALANINE | METHY...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+6 | n/a | n/a | n/a | n/a | 8.05 | 37 |
Shanghai Center for Systems Biomedicine, School of Pharmacy, and State Key Laboratory of Microbial Metabolism & School of Life Sciences and Biotechnology | Assay Description To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad... | ACS Chem Biol 9: 897-903 (2014) Article DOI: 10.1021/cb500009r BindingDB Entry DOI: 10.7270/Q2S75F0F | |||||||||||
More data for this Ligand-Target Pair |