Compile Data Set for Download or QSAR

Found 390 hits of ic50 for UniProtKB: P32418   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140907 (US8912224, 345) Show SMILES Cc1ccccc1[C@@H]1CCc2cc(Oc3ncc(s3)C(=O)NCCOP(O)(O)=O)ccc2O1 Show InChI InChI=1S/C22H23N2O7PS/c1-14-4-2-3-5-17(14)19-8-6-15-12-16(7-9-18(15)31-19)30-22-24-13-20(33-22)21(25)23-10-11-29-32(26,27)28/h2-5,7,9,12-13,19H,6,8,10-11H2,1H3,(H,23,25)(H2,26,27,28)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140915 (US8912224, 353) Show SMILES O=C(NCc1ccno1)c1csc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)n1 Show InChI InChI=1S/C23H19N3O4S/c27-22(24-13-18-10-11-25-30-18)19-14-31-23(26-19)28-17-7-9-21-16(12-17)6-8-20(29-21)15-4-2-1-3-5-15/h1-5,7,9-12,14,20H,6,8,13H2,(H,24,27)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140778 (US8912224, 210) Show SMILES C(NCc1cnc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)s1)c1ccno1 Show InChI InChI=1S/C23H21N3O3S/c1-2-4-16(5-3-1)21-8-6-17-12-18(7-9-22(17)28-21)27-23-25-15-20(30-23)14-24-13-19-10-11-26-29-19/h1-5,7,9-12,15,21,24H,6,8,13-14H2/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140630 (US8912224, 60 | US8912224, 61) Show SMILES O=C(NCc1ccncc1)c1cnc(Oc2ccc3OC(CCc3c2)c2ccsc2)s1 Show InChI InChI=1S/C23H19N3O3S2/c27-22(25-12-15-5-8-24-9-6-15)21-13-26-23(31-21)28-18-2-4-19-16(11-18)1-3-20(29-19)17-7-10-30-14-17/h2,4-11,13-14,20H,1,3,12H2,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140830 (US8912224, 266) Show SMILES OCCNCc1cnc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C21H22N2O3S/c24-11-10-22-13-18-14-23-21(27-18)25-17-7-9-20-16(12-17)6-8-19(26-20)15-4-2-1-3-5-15/h1-5,7,9,12,14,19,22,24H,6,8,10-11,13H2/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140874 (US8912224, 311) Show SMILES OCCNCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C21H22N2O3S/c24-11-10-22-13-18-14-23-21(27-18)25-17-7-9-20-16(12-17)6-8-19(26-20)15-4-2-1-3-5-15/h1-5,7,9,12,14,19,22,24H,6,8,10-11,13H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140875 (US8912224, 312) Show SMILES OCCN(CCO)C(=O)c1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C23H24N2O5S/c26-12-10-25(11-13-27)22(28)21-15-24-23(31-21)29-18-7-9-20-17(14-18)6-8-19(30-20)16-4-2-1-3-5-16/h1-5,7,9,14-15,19,26-27H,6,8,10-13H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140877 (US8912224, 314) Show SMILES O=C(N1CCOCC1)c1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C23H22N2O4S/c26-22(25-10-12-27-13-11-25)21-15-24-23(30-21)28-18-7-9-20-17(14-18)6-8-19(29-20)16-4-2-1-3-5-16/h1-5,7,9,14-15,19H,6,8,10-13H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140879 (US8912224, 317) Show SMILES CCCCNC(=O)c1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C23H24N2O3S/c1-2-3-13-24-22(26)21-15-25-23(29-21)27-18-10-12-20-17(14-18)9-11-19(28-20)16-7-5-4-6-8-16/h4-8,10,12,14-15,19H,2-3,9,11,13H2,1H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140880 (US8912224, 318) Show SMILES CC(C)CNC(=O)c1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C23H24N2O3S/c1-15(2)13-24-22(26)21-14-25-23(29-21)27-18-9-11-20-17(12-18)8-10-19(28-20)16-6-4-3-5-7-16/h3-7,9,11-12,14-15,19H,8,10,13H2,1-2H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140888 (US8912224, 326) Show SMILES Cc1ccccc1[C@@H]1CCc2cc(Oc3ncc(s3)C(=O)NCCO)ccc2O1 Show InChI InChI=1S/C22H22N2O4S/c1-14-4-2-3-5-17(14)19-8-6-15-12-16(7-9-18(15)28-19)27-22-24-13-20(29-22)21(26)23-10-11-25/h2-5,7,9,12-13,19,25H,6,8,10-11H2,1H3,(H,23,26)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140810 (US8912224, 245) Show SMILES COC(=O)CNCc1cnc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C22H22N2O4S/c1-26-21(25)14-23-12-18-13-24-22(29-18)27-17-8-10-20-16(11-17)7-9-19(28-20)15-5-3-2-4-6-15/h2-6,8,10-11,13,19,23H,7,9,12,14H2,1H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140629 (US8912224, 59) Show SMILES Cc1nc(Oc2ccc3OC(CCc3c2)c2ccccc2)sc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C26H23N3O3S/c1-17-24(25(30)28-16-18-11-13-27-14-12-18)33-26(29-17)31-21-8-10-23-20(15-21)7-9-22(32-23)19-5-3-2-4-6-19/h2-6,8,10-15,22H,7,9,16H2,1H3,(H,28,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140620 (US8912224, 49) Show SMILES Fc1cccc(c1)C1CCc2cc(Oc3ncc(s3)C(=O)NCc3ccno3)ccc2O1 Show InChI InChI=1S/C23H18FN3O4S/c24-16-3-1-2-14(10-16)19-6-4-15-11-17(5-7-20(15)30-19)29-23-26-13-21(32-23)22(28)25-12-18-8-9-27-31-18/h1-3,5,7-11,13,19H,4,6,12H2,(H,25,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140619 (US8912224, 48) Show SMILES O=C(NCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1)c1ccno1 Show InChI InChI=1S/C23H19N3O4S/c27-22(21-10-11-26-30-21)24-13-18-14-25-23(31-18)28-17-7-9-20-16(12-17)6-8-19(29-20)15-4-2-1-3-5-15/h1-5,7,9-12,14,19H,6,8,13H2,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140618 (US8912224, 47) Show SMILES O=S(=O)(NCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1)c1cccnc1 Show InChI InChI=1S/C24H21N3O4S2/c28-33(29,21-7-4-12-25-16-21)27-15-20-14-26-24(32-20)30-19-9-11-23-18(13-19)8-10-22(31-23)17-5-2-1-3-6-17/h1-7,9,11-14,16,22,27H,8,10,15H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140727 (US8912224, 159) Show SMILES C(NCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1)c1ccno1 Show InChI InChI=1S/C23H21N3O3S/c1-2-4-16(5-3-1)21-8-6-17-12-18(7-9-22(17)28-21)27-23-25-15-20(30-23)14-24-13-19-10-11-26-29-19/h1-5,7,9-12,15,21,24H,6,8,13-14H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140739 (US8912224, 171) Show SMILES O=C(NCc1ccno1)c1cnc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C23H19N3O4S/c27-22(24-13-18-10-11-26-30-18)21-14-25-23(31-21)28-17-7-9-20-16(12-17)6-8-19(29-20)15-4-2-1-3-5-15/h1-5,7,9-12,14,19H,6,8,13H2,(H,24,27)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140772 (US8912224, 204) Show SMILES OCCNC(=O)c1cnc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C21H20N2O4S/c24-11-10-22-20(25)19-13-23-21(28-19)26-16-7-9-18-15(12-16)6-8-17(27-18)14-4-2-1-3-5-14/h1-5,7,9,12-13,17,24H,6,8,10-11H2,(H,22,25)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM47064 (US8912224, 57) Show SMILES NCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C19H18N2O2S/c20-11-16-12-21-19(24-16)22-15-7-9-18-14(10-15)6-8-17(23-18)13-4-2-1-3-5-13/h1-5,7,9-10,12,17H,6,8,11,20H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the PBX Calcium Assay Kit from BD (Becton, Dickinson and Company) with...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140586 (US8912224, 15) Show SMILES O=C(NCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1)c1cccnc1 Show InChI InChI=1S/C25H21N3O3S/c29-24(19-7-4-12-26-14-19)27-15-21-16-28-25(32-21)30-20-9-11-23-18(13-20)8-10-22(31-23)17-5-2-1-3-6-17/h1-7,9,11-14,16,22H,8,10,15H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140587 (US8912224, 16) Show SMILES O=C(Cc1cccnc1)NCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C26H23N3O3S/c30-25(13-18-5-4-12-27-15-18)28-16-22-17-29-26(33-22)31-21-9-11-24-20(14-21)8-10-23(32-24)19-6-2-1-3-7-19/h1-7,9,11-12,14-15,17,23H,8,10,13,16H2,(H,28,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140590 (US8912224, 19) Show SMILES O=C(Cc1ccccn1)NCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C26H23N3O3S/c30-25(15-20-8-4-5-13-27-20)28-16-22-17-29-26(33-22)31-21-10-12-24-19(14-21)9-11-23(32-24)18-6-2-1-3-7-18/h1-8,10,12-14,17,23H,9,11,15-16H2,(H,28,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140592 (US8912224, 21) Show SMILES Cc1nccc(CNC(=O)c2cnc(Oc3ccc4OC(CCc4c3)c3ccccc3)s2)n1 Show InChI InChI=1S/C25H22N4O3S/c1-16-26-12-11-19(29-16)14-27-24(30)23-15-28-25(33-23)31-20-8-10-22-18(13-20)7-9-21(32-22)17-5-3-2-4-6-17/h2-6,8,10-13,15,21H,7,9,14H2,1H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140595 (US8912224, 24) Show SMILES O=C(NCc1ccno1)c1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C23H19N3O4S/c27-22(24-13-18-10-11-26-30-18)21-14-25-23(31-21)28-17-7-9-20-16(12-17)6-8-19(29-20)15-4-2-1-3-5-15/h1-5,7,9-12,14,19H,6,8,13H2,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140600 (US8912224, 29) Show SMILES CN(C)c1cc(CNC(=O)c2cnc(Oc3ccc4OC(CCc4c3)c3ccccc3)s2)ccn1 Show InChI InChI=1S/C27H26N4O3S/c1-31(2)25-14-18(12-13-28-25)16-29-26(32)24-17-30-27(35-24)33-21-9-11-23-20(15-21)8-10-22(34-23)19-6-4-3-5-7-19/h3-7,9,11-15,17,22H,8,10,16H2,1-2H3,(H,29,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140607 (US8912224, 36) Show SMILES O=C(NCc1ccncc1)c1cnc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C25H21N3O3S/c29-24(27-15-17-10-12-26-13-11-17)23-16-28-25(32-23)30-20-7-9-22-19(14-20)6-8-21(31-22)18-4-2-1-3-5-18/h1-5,7,9-14,16,21H,6,8,15H2,(H,27,29)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140616 (US8912224, 45) Show SMILES Fc1cccc(c1)C1CCc2cc(Oc3ncc(CNC(=O)Cc4cccnc4)s3)ccc2O1 Show InChI InChI=1S/C26H22FN3O3S/c27-20-5-1-4-18(12-20)23-8-6-19-13-21(7-9-24(19)33-23)32-26-30-16-22(34-26)15-29-25(31)11-17-3-2-10-28-14-17/h1-5,7,9-10,12-14,16,23H,6,8,11,15H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140913 (US8912224, 351) Show SMILES CCCNC(=O)c1csc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)n1 Show InChI InChI=1S/C22H22N2O3S/c1-2-12-23-21(25)18-14-28-22(24-18)26-17-9-11-20-16(13-17)8-10-19(27-20)15-6-4-3-5-7-15/h3-7,9,11,13-14,19H,2,8,10,12H2,1H3,(H,23,25)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140912 (US8912224, 350) Show SMILES OCCNC(=O)c1csc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)n1 Show InChI InChI=1S/C21H20N2O4S/c24-11-10-22-20(25)17-13-28-21(23-17)26-16-7-9-19-15(12-16)6-8-18(27-19)14-4-2-1-3-5-14/h1-5,7,9,12-13,18,24H,6,8,10-11H2,(H,22,25)/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140916 (US8912224, 354) Show SMILES CC(O)CNC(=O)c1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C22H22N2O4S/c1-14(25)12-23-21(26)20-13-24-22(29-20)27-17-8-10-19-16(11-17)7-9-18(28-19)15-5-3-2-4-6-15/h2-6,8,10-11,13-14,18,25H,7,9,12H2,1H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140908 (US8912224, 346) Show SMILES O=C(CN1CCCC1)NCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C25H27N3O3S/c29-24(17-28-12-4-5-13-28)26-15-21-16-27-25(32-21)30-20-9-11-23-19(14-20)8-10-22(31-23)18-6-2-1-3-7-18/h1-3,6-7,9,11,14,16,22H,4-5,8,10,12-13,15,17H2,(H,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140928 (US8912224, 366) Show SMILES COc1c(F)cccc1C1CCc2cc(Oc3ncc(s3)C(=O)NCc3ccno3)ccc2O1 Show InChI InChI=1S/C24H20FN3O5S/c1-30-22-17(3-2-4-18(22)25)20-7-5-14-11-15(6-8-19(14)32-20)31-24-27-13-21(34-24)23(29)26-12-16-9-10-28-33-16/h2-4,6,8-11,13,20H,5,7,12H2,1H3,(H,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140785 (US8912224, 217) Show SMILES Fc1ccc(F)c(c1)C1CCc2cc(Oc3ncc(s3)C(=O)NCc3ccno3)ccc2O1 Show InChI InChI=1S/C23H17F2N3O4S/c24-14-2-4-18(25)17(10-14)20-5-1-13-9-15(3-6-19(13)31-20)30-23-27-12-21(33-23)22(29)26-11-16-7-8-28-32-16/h2-4,6-10,12,20H,1,5,11H2,(H,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140823 (US8912224, 258) Show SMILES OCCN(CCO)Cc1cnc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C23H26N2O4S/c26-12-10-25(11-13-27)16-20-15-24-23(30-20)28-19-7-9-22-18(14-19)6-8-21(29-22)17-4-2-1-3-5-17/h1-5,7,9,14-15,21,26-27H,6,8,10-13,16H2/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140847 (US8912224, 284) Show SMILES N[C@H]1CC1NC(=O)c1cnc(Oc2ccc3O[C@@H](CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C22H21N3O3S/c23-16-11-17(16)25-21(26)20-12-24-22(29-20)27-15-7-9-19-14(10-15)6-8-18(28-19)13-4-2-1-3-5-13/h1-5,7,9-10,12,16-18H,6,8,11,23H2,(H,25,26)/t16-,17?,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140857 (US8912224, 294) Show SMILES COC(=O)CNC(=O)c1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C22H20N2O5S/c1-27-20(25)13-23-21(26)19-12-24-22(30-19)28-16-8-10-18-15(11-16)7-9-17(29-18)14-5-3-2-4-6-14/h2-6,8,10-12,17H,7,9,13H2,1H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140863 (US8912224, 300) Show SMILES Cc1ccccc1C1CCc2cc(Oc3ncc(s3)C(=O)N3CC[C@@H](O)C3)ccc2O1 Show InChI InChI=1S/C24H24N2O4S/c1-15-4-2-3-5-19(15)21-8-6-16-12-18(7-9-20(16)30-21)29-24-25-13-22(31-24)23(28)26-11-10-17(27)14-26/h2-5,7,9,12-13,17,21,27H,6,8,10-11,14H2,1H3/t17-,21?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140870 (US8912224, 307) Show SMILES CC(C)OC(=O)CNC(=O)c1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C24H24N2O5S/c1-15(2)29-22(27)14-25-23(28)21-13-26-24(32-21)30-18-9-11-20-17(12-18)8-10-19(31-20)16-6-4-3-5-7-16/h3-7,9,11-13,15,19H,8,10,14H2,1-2H3,(H,25,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140871 (US8912224, 308) Show SMILES CCOC(=O)CNC(=O)c1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C23H22N2O5S/c1-2-28-21(26)14-24-22(27)20-13-25-23(31-20)29-17-9-11-19-16(12-17)8-10-18(30-19)15-6-4-3-5-7-15/h3-7,9,11-13,18H,2,8,10,14H2,1H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140887 (US8912224, 325) Show SMILES Cc1ccccc1[C@H]1CCc2cc(Oc3ncc(s3)C(=O)NCCO)ccc2O1 Show InChI InChI=1S/C22H22N2O4S/c1-14-4-2-3-5-17(14)19-8-6-15-12-16(7-9-18(15)28-19)27-22-24-13-20(29-22)21(26)23-10-11-25/h2-5,7,9,12-13,19,25H,6,8,10-11H2,1H3,(H,23,26)/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140911 (US8912224, 349) Show SMILES Cc1ccc(F)cc1C1CCc2cc(Oc3ncc(s3)C(=O)NCCN3CCNC3=O)ccc2O1 Show InChI InChI=1S/C25H25FN4O4S/c1-15-2-4-17(26)13-19(15)21-6-3-16-12-18(5-7-20(16)34-21)33-25-29-14-22(35-25)23(31)27-8-10-30-11-9-28-24(30)32/h2,4-5,7,12-14,21H,3,6,8-11H2,1H3,(H,27,31)(H,28,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140629 (US8912224, 59) Show SMILES Cc1nc(Oc2ccc3OC(CCc3c2)c2ccccc2)sc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C26H23N3O3S/c1-17-24(25(30)28-16-18-11-13-27-14-12-18)33-26(29-17)31-21-8-10-23-20(15-21)7-9-22(32-23)19-5-3-2-4-6-19/h2-6,8,10-15,22H,7,9,16H2,1H3,(H,28,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the PBX Calcium Assay Kit from BD (Becton, Dickinson and Company) with...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140888 (US8912224, 326) Show SMILES Cc1ccccc1[C@@H]1CCc2cc(Oc3ncc(s3)C(=O)NCCO)ccc2O1 Show InChI InChI=1S/C22H22N2O4S/c1-14-4-2-3-5-17(14)19-8-6-15-12-16(7-9-18(15)28-19)27-22-24-13-20(29-22)21(26)23-10-11-25/h2-5,7,9,12-13,19,25H,6,8,10-11H2,1H3,(H,23,26)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the PBX Calcium Assay Kit from BD (Becton, Dickinson and Company) with...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140658 (US8912224, 89) Show SMILES O=C(NCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1)c1ccncn1 Show InChI InChI=1S/C24H20N4O3S/c29-23(20-10-11-25-15-28-20)26-13-19-14-27-24(32-19)30-18-7-9-22-17(12-18)6-8-21(31-22)16-4-2-1-3-5-16/h1-5,7,9-12,14-15,21H,6,8,13H2,(H,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140672 (US8912224, 103) Show SMILES C(NC1CC1)c1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C22H22N2O2S/c1-2-4-15(5-3-1)20-10-6-16-12-18(9-11-21(16)26-20)25-22-24-14-19(27-22)13-23-17-7-8-17/h1-5,9,11-12,14,17,20,23H,6-8,10,13H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140676 (US8912224, 107 | US8912224, 108) Show SMILES FC(F)(F)CNCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C21H19F3N2O2S/c22-21(23,24)13-25-11-17-12-26-20(29-17)27-16-7-9-19-15(10-16)6-8-18(28-19)14-4-2-1-3-5-14/h1-5,7,9-10,12,18,25H,6,8,11,13H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140679 (US8912224, 110) Show SMILES C(NC1CCC1)c1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C23H24N2O2S/c1-2-5-16(6-3-1)21-11-9-17-13-19(10-12-22(17)27-21)26-23-25-15-20(28-23)14-24-18-7-4-8-18/h1-3,5-6,10,12-13,15,18,21,24H,4,7-9,11,14H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140683 (US8912224, 114) Show SMILES COCCNCc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C22H24N2O3S/c1-25-12-11-23-14-19-15-24-22(28-19)26-18-8-10-21-17(13-18)7-9-20(27-21)16-5-3-2-4-6-16/h2-6,8,10,13,15,20,23H,7,9,11-12,14H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair
Sodium/calcium exchanger 1 (Homo sapiens (Human))	BDBM140685 (US8912224, 116) Show SMILES CC(CN)Cc1cnc(Oc2ccc3OC(CCc3c2)c2ccccc2)s1 Show InChI InChI=1S/C22H24N2O2S/c1-15(13-23)11-19-14-24-22(27-19)25-18-8-10-21-17(12-18)7-9-20(26-21)16-5-3-2-4-6-16/h2-6,8,10,12,14-15,20H,7,9,11,13,23H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...				US Patent US8912224 (2014) BindingDB Entry DOI: 10.7270/Q22F7M52
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 390 total )  |  Next  |  Last  >>

Jump to: