Compile Data Set for Download or QSAR

Found 8 hits of ic50 for UniProtKB: P27296   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM213233 (Telomestatin (TMS)) Show SMILES [H]C12CSC(=N1)c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1nc(oc1C)-c1nc2oc1C |c:4| Show InChI InChI=1S/C26H14N8O7S/c1-9-17-24-30-14(6-39-24)21-28-12(4-37-21)19-27-11(3-35-19)20-29-13(5-36-20)22-31-15(7-38-22)26-32-16(8-42-26)23-33-18(10(2)40-23)25(34-17)41-9/h3-7,16H,8H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM213233 (Telomestatin (TMS)) Show SMILES [H]C12CSC(=N1)c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1nc(oc1C)-c1nc2oc1C |c:4| Show InChI InChI=1S/C26H14N8O7S/c1-9-17-24-30-14(6-39-24)21-28-12(4-37-21)19-27-11(3-35-19)20-29-13(5-36-20)22-31-15(7-38-22)26-32-16(8-42-26)23-33-18(10(2)40-23)25(34-17)41-9/h3-7,16H,8H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM50376748 (CHEMBL259739 | Phen-DC3) Show SMILES C[n+]1cc(NC(=O)c2ccc3ccc4ccc(nc4c3n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-19-25(17-23-7-3-5-9-29(23)39)35-33(41)27-15-13-21-11-12-22-14-16-28(38-32(22)31(21)37-27)34(42)36-26-18-24-8-4-6-10-30(24)40(2)20-26/h3-20H,1-2H3/p+2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM213234 (Phen-DC6) Show SMILES C[n+]1cccc2cc(NC(=O)c3ccc4ccc5ccc(nc5c4n3)C(=O)Nc3ccc4[n+](C)cccc4c3)ccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-17-3-5-23-19-25(11-15-29(23)39)35-33(41)27-13-9-21-7-8-22-10-14-28(38-32(22)31(21)37-27)34(42)36-26-12-16-30-24(20-26)6-4-18-40(30)2/h3-20H,1-2H3/p+2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM213234 (Phen-DC6) Show SMILES C[n+]1cccc2cc(NC(=O)c3ccc4ccc5ccc(nc5c4n3)C(=O)Nc3ccc4[n+](C)cccc4c3)ccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-17-3-5-23-19-25(11-15-29(23)39)35-33(41)27-13-9-21-7-8-22-10-14-28(38-32(22)31(21)37-27)34(42)36-26-12-16-30-24(20-26)6-4-18-40(30)2/h3-20H,1-2H3/p+2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM50376748 (CHEMBL259739 | Phen-DC3) Show SMILES C[n+]1cc(NC(=O)c2ccc3ccc4ccc(nc4c3n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12 Show InChI InChI=1S/C34H24N6O2/c1-39-19-25(17-23-7-3-5-9-29(23)39)35-33(41)27-15-13-21-11-12-22-14-16-28(38-32(22)31(21)37-27)34(42)36-26-18-24-8-4-6-10-30(24)40(2)20-26/h3-20H,1-2H3/p+2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM50107609 (5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...) Show SMILES C[n+]1ccc(cc1)-c1c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc1n2 Show InChI InChI=1S/C44H37N8/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31/h5-28H,1-4H3,(H,45,46,47,48)/q+3/p+1/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair
ATP-dependent DNA helicase DinG (Escherichia coli (Enterobacteria))	BDBM50107609 (5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...) Show SMILES C[n+]1ccc(cc1)-c1c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc1n2 Show InChI InChI=1S/C44H37N8/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31/h5-28H,1-4H3,(H,45,46,47,48)/q+3/p+1/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	8.0	n/a
National Institutes of Health, National Institutes of Health Biomedical Research Center					Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...				J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS
					More data for this Ligand-Target Pair