Found 11 hits Enz. Inhib. hit(s) with all data for entry = 4878 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Alpha-1B adrenergic receptor
(C.H.O.) | BDBM29568
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) | Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Children's Medical Research Center
Curated by PDSP Ki Database
| |
Eur J Pharmacol 268: 399-407 (1994)
Article DOI: 10.1016/0922-4106(94)90065-5
BindingDB Entry DOI: 10.7270/Q26W98KS |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(C.H.O.) | BDBM81444
(CAS_185453 | NSC_185453 | WB 4101 | WB-4101)Show InChI InChI=1S/C25H27NO5/c1-27-21-13-8-14-22(28-2)25(21)29-16-15-26-17-23-24(18-9-4-3-5-10-18)31-20-12-7-6-11-19(20)30-23/h3-14,23-24,26H,15-17H2,1-2H3 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Children's Medical Research Center
Curated by PDSP Ki Database
| |
Eur J Pharmacol 268: 399-407 (1994)
Article DOI: 10.1016/0922-4106(94)90065-5
BindingDB Entry DOI: 10.7270/Q26W98KS |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(C.H.O.) | BDBM31046
(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)Show InChI InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19) | Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Children's Medical Research Center
Curated by PDSP Ki Database
| |
Eur J Pharmacol 268: 399-407 (1994)
Article DOI: 10.1016/0922-4106(94)90065-5
BindingDB Entry DOI: 10.7270/Q26W98KS |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(C.H.O.) | BDBM50033112
(6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyla...)Show SMILES COc1ccccc1N1CCN(CCCNc2c(C)c(=O)n(C)c(=O)n2C)CC1 Show InChI InChI=1S/C21H31N5O3/c1-16-19(23(2)21(28)24(3)20(16)27)22-10-7-11-25-12-14-26(15-13-25)17-8-5-6-9-18(17)29-4/h5-6,8-9,22H,7,10-15H2,1-4H3 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Children's Medical Research Center
Curated by PDSP Ki Database
| |
Eur J Pharmacol 268: 399-407 (1994)
Article DOI: 10.1016/0922-4106(94)90065-5
BindingDB Entry DOI: 10.7270/Q26W98KS |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(C.H.O.) | BDBM30712
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)Show InChI InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18) | Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
DrugBank
KEGG
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Children's Medical Research Center
Curated by PDSP Ki Database
| |
Eur J Pharmacol 268: 399-407 (1994)
Article DOI: 10.1016/0922-4106(94)90065-5
BindingDB Entry DOI: 10.7270/Q26W98KS |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(C.H.O.) | BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 670 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Children's Medical Research Center
Curated by PDSP Ki Database
| |
Eur J Pharmacol 268: 399-407 (1994)
Article DOI: 10.1016/0922-4106(94)90065-5
BindingDB Entry DOI: 10.7270/Q26W98KS |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(C.H.O.) | BDBM35234
(DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradre...)Show InChI InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 920 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Children's Medical Research Center
Curated by PDSP Ki Database
| |
Eur J Pharmacol 268: 399-407 (1994)
Article DOI: 10.1016/0922-4106(94)90065-5
BindingDB Entry DOI: 10.7270/Q26W98KS |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(C.H.O.) | BDBM84342
(4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol...)Show InChI InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
KEGG
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Children's Medical Research Center
Curated by PDSP Ki Database
| |
Eur J Pharmacol 268: 399-407 (1994)
Article DOI: 10.1016/0922-4106(94)90065-5
BindingDB Entry DOI: 10.7270/Q26W98KS |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(C.H.O.) | BDBM25392
(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Children's Medical Research Center
Curated by PDSP Ki Database
| |
Eur J Pharmacol 268: 399-407 (1994)
Article DOI: 10.1016/0922-4106(94)90065-5
BindingDB Entry DOI: 10.7270/Q26W98KS |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(C.H.O.) | BDBM50026777
(2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol | 2-A...)Show InChI InChI=1S/C11H17NO3/c1-7(12)11(13)9-6-8(14-2)4-5-10(9)15-3/h4-7,11,13H,12H2,1-3H3 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Children's Medical Research Center
Curated by PDSP Ki Database
| |
Eur J Pharmacol 268: 399-407 (1994)
Article DOI: 10.1016/0922-4106(94)90065-5
BindingDB Entry DOI: 10.7270/Q26W98KS |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(C.H.O.) | BDBM36024
((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...)Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Children's Medical Research Center
Curated by PDSP Ki Database
| |
Eur J Pharmacol 268: 399-407 (1994)
Article DOI: 10.1016/0922-4106(94)90065-5
BindingDB Entry DOI: 10.7270/Q26W98KS |
More data for this
Ligand-Target Pair | |
Search and Browse
