Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50010495 (Acetyl-Ser-Leu-Asn-Phe-[CH(OH)CH2N]Pro-Ile-Val-OMe...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro binding affinity of the compound against HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50010497 (Acetyl-Ser-Leu-Asn-Phe-[S]-[CH(OH)CH2N]Pro-Ile-Val...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50010497 (Acetyl-Ser-Leu-Asn-Phe-[S]-[CH(OH)CH2N]Pro-Ile-Val...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured (exp 2) | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50011680 (CHEMBL3351098 | Qua-Asn-Phe-HEA(S)-Pro-Ile-Phe-OMe) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50011684 (CHEMBL3350878 | Cbz-Asn-Phe-HEA(S)-Pro-Ile-Phe-OMe) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50010495 (Acetyl-Ser-Leu-Asn-Phe-[CH(OH)CH2N]Pro-Ile-Val-OMe...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro binding affinity of the compound against HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50011682 (Ac-Ser-Leu-Asn-Phe-HEA(S)-Pro-O-terbutyl | BDBM504...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50011687 (Ac-Ser-Leu-Asn-Phe-HEA(R)-Pro-O-terbutyl | CHEMBL3...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50011688 (Boc-Asn-Phe-HEA(R)-Pro-Ile-Val-OMe | CHEMBL3349554) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50005687 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured (exp 2) | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50010497 (Acetyl-Ser-Leu-Asn-Phe-[S]-[CH(OH)CH2N]Pro-Ile-Val...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50010497 (Acetyl-Ser-Leu-Asn-Phe-[S]-[CH(OH)CH2N]Pro-Ile-Val...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50005687 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50010500 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro binding affinity of the compound against HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50010500 (1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50011683 (Boc-Asn-Phe-HEA(S)-Pro-Ile-Val-OMe | CHEMBL3349553) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured | J Med Chem 34: 1222-5 (1991) BindingDB Entry DOI: 10.7270/Q2057DWM | |||||||||||
More data for this Ligand-Target Pair |