Compile Data Set for Download or QSAR

Found 36 hits Enz. Inhib. hit(s) with all data for entry = 50007148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta-2B chain (Bos taurus)	BDBM50035218 (CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...) Show SMILES COc1cc(cc(OC)c1OC)[C@H]1[C@@H]2[C@H](COC2=O)[C@@H](O)c2cc3OCOc3cc12 |r| Show InChI InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin beta-2B chain (Bos taurus)	BDBM50005480 ((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin beta-2B chain (Bos taurus)	BDBM50059123 (2-(3-Methoxy-phenyl)-5-methyl-1H-[1,8]naphthyridin...) Show SMILES COc1cccc(c1)-c1cc(O)c2c(C)ccnc2n1 Show InChI InChI=1S/C16H14N2O2/c1-10-6-7-17-16-15(10)14(19)9-13(18-16)11-4-3-5-12(8-11)20-2/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059100 (6-Chloro-2-(3-methoxy-phenyl)-1H-[1,8]naphthyridin...) Show SMILES COc1cccc(c1)-c1cc(O)c2cc(Cl)cnc2n1 Show InChI InChI=1S/C15H11ClN2O2/c1-20-11-4-2-3-9(5-11)13-7-14(19)12-6-10(16)8-17-15(12)18-13/h2-8H,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059117 (2-(3-Methoxy-phenyl)-7-methyl-1H-[1,8]naphthyridin...) Show SMILES COc1cccc(c1)-c1cc(O)c2ccc(C)nc2n1 Show InChI InChI=1S/C16H14N2O2/c1-10-6-7-13-15(19)9-14(18-16(13)17-10)11-4-3-5-12(8-11)20-2/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059111 (2-(3-Methoxy-phenyl)-6-methyl-1H-[1,8]naphthyridin...) Show SMILES COc1cccc(c1)-c1cc(O)c2cc(C)cnc2n1 Show InChI InChI=1S/C16H14N2O2/c1-10-6-13-15(19)8-14(18-16(13)17-9-10)11-4-3-5-12(7-11)20-2/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50014846 ((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...) Show SMILES COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin beta-2B chain (Bos taurus)	BDBM50059103 (2-(3-Methoxy-phenyl)-5,7-dimethyl-1H-[1,8]naphthyr...) Show SMILES COc1cccc(c1)-c1cc(O)c2c(C)cc(C)nc2n1 Show InChI InChI=1S/C17H16N2O2/c1-10-7-11(2)18-17-16(10)15(20)9-14(19-17)12-5-4-6-13(8-12)21-3/h4-9H,1-3H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059122 (2-(3-Methoxy-phenyl)-1H-[1,8]naphthyridin-4-one | ...) Show SMILES COc1cccc(c1)-c1cc(O)c2cccnc2n1 Show InChI InChI=1S/C15H12N2O2/c1-19-11-5-2-4-10(8-11)13-9-14(18)12-6-3-7-16-15(12)17-13/h2-9H,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50041113 (2-(3-Methoxy-phenyl)-1H-quinolin-4-one | CHEMBL276...) Show SMILES COc1cccc(c1)-c1cc(O)c2ccccc2n1 Show InChI InChI=1S/C16H13NO2/c1-19-12-6-4-5-11(9-12)15-10-16(18)13-7-2-3-8-14(13)17-15/h2-10H,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059102 (6-Bromo-2-(3-methoxy-phenyl)-1H-[1,8]naphthyridin-...) Show SMILES COc1cccc(c1)-c1cc(O)c2cc(Br)cnc2n1 Show InChI InChI=1S/C15H11BrN2O2/c1-20-11-4-2-3-9(5-11)13-7-14(19)12-6-10(16)8-17-15(12)18-13/h2-8H,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059124 (2-(4-Chloro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...) Show SMILES Cc1cnc2nc(cc(O)c2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C15H11ClN2O/c1-9-6-12-14(19)7-13(18-15(12)17-8-9)10-2-4-11(16)5-3-10/h2-8H,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059107 (6-Methyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one | CH...) Show SMILES Cc1ccc(cc1)-c1cc(O)c2cc(C)cnc2n1 Show InChI InChI=1S/C16H14N2O/c1-10-3-5-12(6-4-10)14-8-15(19)13-7-11(2)9-17-16(13)18-14/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059097 (5-Methyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one | CH...) Show SMILES Cc1ccc(cc1)-c1cc(O)c2c(C)ccnc2n1 Show InChI InChI=1S/C16H14N2O/c1-10-3-5-12(6-4-10)13-9-14(19)15-11(2)7-8-17-16(15)18-13/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059115 (2-(4-Chloro-phenyl)-5-methyl-1H-[1,8]naphthyridin-...) Show SMILES Cc1ccnc2nc(cc(O)c12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C15H11ClN2O/c1-9-6-7-17-15-14(9)13(19)8-12(18-15)10-2-4-11(16)5-3-10/h2-8H,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059119 (7-Methyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one | CH...) Show SMILES Cc1ccc(cc1)-c1cc(O)c2ccc(C)nc2n1 Show InChI InChI=1S/C16H14N2O/c1-10-3-6-12(7-4-10)14-9-15(19)13-8-5-11(2)17-16(13)18-14/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059118 (2-(4-Methoxy-phenyl)-6-methyl-1H-[1,8]naphthyridin...) Show SMILES COc1ccc(cc1)-c1cc(O)c2cc(C)cnc2n1 Show InChI InChI=1S/C16H14N2O2/c1-10-7-13-15(19)8-14(18-16(13)17-9-10)11-3-5-12(20-2)6-4-11/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059114 (2-(4-Methoxy-phenyl)-5-methyl-1H-[1,8]naphthyridin...) Show SMILES COc1ccc(cc1)-c1cc(O)c2c(C)ccnc2n1 Show InChI InChI=1S/C16H14N2O2/c1-10-7-8-17-16-15(10)14(19)9-13(18-16)11-3-5-12(20-2)6-4-11/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059120 (5,7-Dimethyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one ...) Show SMILES Cc1ccc(cc1)-c1cc(O)c2c(C)cc(C)nc2n1 Show InChI InChI=1S/C17H16N2O/c1-10-4-6-13(7-5-10)14-9-15(20)16-11(2)8-12(3)18-17(16)19-14/h4-9H,1-3H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059099 (2-(4-Chloro-phenyl)-7-methyl-1H-[1,8]naphthyridin-...) Show SMILES Cc1ccc2c(O)cc(nc2n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C15H11ClN2O/c1-9-2-7-12-14(19)8-13(18-15(12)17-9)10-3-5-11(16)6-4-10/h2-8H,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059106 (6-Chloro-2-(4-fluoro-phenyl)-1H-[1,8]naphthyridin-...) Show SMILES Oc1cc(nc2ncc(Cl)cc12)-c1ccc(F)cc1 Show InChI InChI=1S/C14H8ClFN2O/c15-9-5-11-13(19)6-12(18-14(11)17-7-9)8-1-3-10(16)4-2-8/h1-7H,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059125 (2-(4-Fluoro-phenyl)-5-methyl-1H-[1,8]naphthyridin-...) Show SMILES Cc1ccnc2nc(cc(O)c12)-c1ccc(F)cc1 Show InChI InChI=1S/C15H11FN2O/c1-9-6-7-17-15-14(9)13(19)8-12(18-15)10-2-4-11(16)5-3-10/h2-8H,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059105 (2-(2-Methoxy-phenyl)-6-methyl-1H-[1,8]naphthyridin...) Show SMILES COc1ccccc1-c1cc(O)c2cc(C)cnc2n1 Show InChI InChI=1S/C16H14N2O2/c1-10-7-12-14(19)8-13(18-16(12)17-9-10)11-5-3-4-6-15(11)20-2/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059094 (2-(2-Methoxy-phenyl)-5-methyl-1H-[1,8]naphthyridin...) Show SMILES COc1ccccc1-c1cc(O)c2c(C)ccnc2n1 Show InChI InChI=1S/C16H14N2O2/c1-10-7-8-17-16-15(10)13(19)9-12(18-16)11-5-3-4-6-14(11)20-2/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059095 (2-(4-Fluoro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...) Show SMILES Cc1cnc2nc(cc(O)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C15H11FN2O/c1-9-6-12-14(19)7-13(18-15(12)17-8-9)10-2-4-11(16)5-3-10/h2-8H,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059108 (2-(4-Chloro-phenyl)-1H-[1,8]naphthyridin-4-one | C...) Show SMILES Oc1cc(nc2ncccc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C14H9ClN2O/c15-10-5-3-9(4-6-10)12-8-13(18)11-2-1-7-16-14(11)17-12/h1-8H,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059096 (2-(4-Chloro-phenyl)-5,7-dimethyl-1H-[1,8]naphthyri...) Show SMILES Cc1cc(C)c2c(O)cc(nc2n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H13ClN2O/c1-9-7-10(2)18-16-15(9)14(20)8-13(19-16)11-3-5-12(17)6-4-11/h3-8H,1-2H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059112 (2-(4-Methoxy-phenyl)-1H-[1,8]naphthyridin-4-one | ...) Show SMILES COc1ccc(cc1)-c1cc(O)c2cccnc2n1 Show InChI InChI=1S/C15H12N2O2/c1-19-11-6-4-10(5-7-11)13-9-14(18)12-3-2-8-16-15(12)17-13/h2-9H,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059110 (2-(2-Methoxy-phenyl)-1H-[1,8]naphthyridin-4-one | ...) Show SMILES COc1ccccc1-c1cc(O)c2cccnc2n1 Show InChI InChI=1S/C15H12N2O2/c1-19-14-7-3-2-5-10(14)12-9-13(18)11-6-4-8-16-15(11)17-12/h2-9H,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059109 (2-(4-Methoxy-phenyl)-7-methyl-1H-[1,8]naphthyridin...) Show SMILES COc1ccc(cc1)-c1cc(O)c2ccc(C)nc2n1 Show InChI InChI=1S/C16H14N2O2/c1-10-3-8-13-15(19)9-14(18-16(13)17-10)11-4-6-12(20-2)7-5-11/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059116 (2-(4-Fluoro-phenyl)-5,7-dimethyl-1H-[1,8]naphthyri...) Show SMILES Cc1cc(C)c2c(O)cc(nc2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C16H13FN2O/c1-9-7-10(2)18-16-15(9)14(20)8-13(19-16)11-3-5-12(17)6-4-11/h3-8H,1-2H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059101 (2-(4-Fluoro-phenyl)-7-methyl-1H-[1,8]naphthyridin-...) Show SMILES Cc1ccc2c(O)cc(nc2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C15H11FN2O/c1-9-2-7-12-14(19)8-13(18-15(12)17-9)10-3-5-11(16)6-4-10/h2-8H,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059098 (2-(2-Methoxy-phenyl)-5,7-dimethyl-1H-[1,8]naphthyr...) Show SMILES COc1ccccc1-c1cc(O)c2c(C)cc(C)nc2n1 Show InChI InChI=1S/C17H16N2O2/c1-10-8-11(2)18-17-16(10)14(20)9-13(19-17)12-6-4-5-7-15(12)21-3/h4-9H,1-3H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059121 (2-(4-Fluoro-phenyl)-1H-[1,8]naphthyridin-4-one | C...) Show SMILES Oc1cc(nc2ncccc12)-c1ccc(F)cc1 Show InChI InChI=1S/C14H9FN2O/c15-10-5-3-9(4-6-10)12-8-13(18)11-2-1-7-16-14(11)17-12/h1-8H,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059113 (2-(2-Methoxy-phenyl)-7-methyl-1H-[1,8]naphthyridin...) Show SMILES COc1ccccc1-c1cc(O)c2ccc(C)nc2n1 Show InChI InChI=1S/C16H14N2O2/c1-10-7-8-12-14(19)9-13(18-16(12)17-10)11-5-3-4-6-15(11)20-2/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50059104 (2-(4-Methoxy-phenyl)-5,7-dimethyl-1H-[1,8]naphthyr...) Show SMILES COc1ccc(cc1)-c1cc(O)c2c(C)cc(C)nc2n1 Show InChI InChI=1S/C17H16N2O2/c1-10-8-11(2)18-17-16(10)15(20)9-14(19-17)12-4-6-13(21-3)7-5-12/h4-9H,1-3H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair