Compile Data Set for Download or QSAR

Found 71 hits Enz. Inhib. hit(s) with all data for entry = 50017540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50158845 (2-(3-(3-(2-chlorobenzyl)ureido)thiophen-2-yl)-5,6-...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)NCc1ccccc1Cl Show InChI InChI=1S/C17H13ClN4O5S/c18-9-4-2-1-3-8(9)7-19-17(27)20-10-5-6-28-13(10)14-21-11(16(25)26)12(23)15(24)22-14/h1-6,23H,7H2,(H,25,26)(H2,19,20,27)(H,21,22,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving manganese chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50158845 (2-(3-(3-(2-chlorobenzyl)ureido)thiophen-2-yl)-5,6-...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)NCc1ccccc1Cl Show InChI InChI=1S/C17H13ClN4O5S/c18-9-4-2-1-3-8(9)7-19-17(27)20-10-5-6-28-13(10)14-21-11(16(25)26)12(23)15(24)22-14/h1-6,23H,7H2,(H,25,26)(H2,19,20,27)(H,21,22,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 2a BK NS5B deltaC21 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50158845 (2-(3-(3-(2-chlorobenzyl)ureido)thiophen-2-yl)-5,6-...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)NCc1ccccc1Cl Show InChI InChI=1S/C17H13ClN4O5S/c18-9-4-2-1-3-8(9)7-19-17(27)20-10-5-6-28-13(10)14-21-11(16(25)26)12(23)15(24)22-14/h1-6,23H,7H2,(H,25,26)(H2,19,20,27)(H,21,22,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC21 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50158845 (2-(3-(3-(2-chlorobenzyl)ureido)thiophen-2-yl)-5,6-...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)NCc1ccccc1Cl Show InChI InChI=1S/C17H13ClN4O5S/c18-9-4-2-1-3-8(9)7-19-17(27)20-10-5-6-28-13(10)14-21-11(16(25)26)12(23)15(24)22-14/h1-6,23H,7H2,(H,25,26)(H2,19,20,27)(H,21,22,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 3a BK NS5B deltaC21 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183509 (5,6-dihydroxy-2-(3-nitro-2-thienyl)pyrimidine-4-ca...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1[N+]([O-])=O Show InChI InChI=1S/C9H5N3O6S/c13-5-4(9(15)16)10-7(11-8(5)14)6-3(12(17)18)1-2-19-6/h1-2,13H,(H,15,16)(H,10,11,14)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving manganese chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183482 (2-[3-({[(2-chlorobenzyl)amino]carbonyl}amino)-2-th...) Show SMILES Cn1c(nc(C(O)=O)c(O)c1=O)-c1sccc1NC(=O)Nc1ccccc1Cl Show InChI InChI=1S/C17H13ClN4O5S/c1-22-14(21-11(16(25)26)12(23)15(22)24)13-10(6-7-28-13)20-17(27)19-9-5-3-2-4-8(9)18/h2-7,23H,1H3,(H,25,26)(H2,19,20,27)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving manganese chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50158845 (2-(3-(3-(2-chlorobenzyl)ureido)thiophen-2-yl)-5,6-...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)NCc1ccccc1Cl Show InChI InChI=1S/C17H13ClN4O5S/c18-9-4-2-1-3-8(9)7-19-17(27)20-10-5-6-28-13(10)14-21-11(16(25)26)12(23)15(24)22-14/h1-6,23H,7H2,(H,25,26)(H2,19,20,27)(H,21,22,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50158845 (2-(3-(3-(2-chlorobenzyl)ureido)thiophen-2-yl)-5,6-...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)NCc1ccccc1Cl Show InChI InChI=1S/C17H13ClN4O5S/c18-9-4-2-1-3-8(9)7-19-17(27)20-10-5-6-28-13(10)14-21-11(16(25)26)12(23)15(24)22-14/h1-6,23H,7H2,(H,25,26)(H2,19,20,27)(H,21,22,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving magnesium chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183496 (5,6-dihydroxy-2-{3-[(1H-indol-3-ylacetyl)amino]-2-...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)Cc1c[nH]c2ccccc12 Show InChI InChI=1S/C19H14N4O5S/c24-13(7-9-8-20-11-4-2-1-3-10(9)11)21-12-5-6-29-16(12)17-22-14(19(27)28)15(25)18(26)23-17/h1-6,8,20,25H,7H2,(H,21,24)(H,27,28)(H,22,23,26)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183486 (5,6-dihydroxy-2-(1,3-thiazol-2-yl)pyrimidine-4-car...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1nccs1 Show InChI InChI=1S/C8H5N3O4S/c12-4-3(8(14)15)10-5(11-6(4)13)7-9-1-2-16-7/h1-2,12H,(H,14,15)(H,10,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving manganese chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183499 (2-(3-{[(2-chlorophenyl)acetyl]amino}-2-thienyl)-5,...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)Cc1ccccc1Cl Show InChI InChI=1S/C17H12ClN3O5S/c18-9-4-2-1-3-8(9)7-11(22)19-10-5-6-27-14(10)15-20-12(17(25)26)13(23)16(24)21-15/h1-6,23H,7H2,(H,19,22)(H,25,26)(H,20,21,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183504 (2-{3-[(1-benzothien-3-ylacetyl)amino]-2-thienyl}-5...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)Cc1csc2ccccc12 Show InChI InChI=1S/C19H13N3O5S2/c23-13(7-9-8-29-12-4-2-1-3-10(9)12)20-11-5-6-28-16(11)17-21-14(19(26)27)15(24)18(25)22-17/h1-6,8,24H,7H2,(H,20,23)(H,26,27)(H,21,22,25)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183510 (2-(3-{[(benzylamino)carbonyl]amino}-2-thienyl)-5,6...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)NCc1ccccc1 Show InChI InChI=1S/C17H14N4O5S/c22-12-11(16(24)25)20-14(21-15(12)23)13-10(6-7-27-13)19-17(26)18-8-9-4-2-1-3-5-9/h1-7,22H,8H2,(H,24,25)(H2,18,19,26)(H,20,21,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183493 (2-(2-furyl)-5,6-dihydroxypyrimidine-4-carboxylic a...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1ccco1 Show InChI InChI=1S/C9H6N2O5/c12-6-5(9(14)15)10-7(11-8(6)13)4-2-1-3-16-4/h1-3,12H,(H,14,15)(H,10,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving manganese chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cccs1 Show InChI InChI=1S/C9H6N2O4S/c12-6-5(9(14)15)10-7(11-8(6)13)4-2-1-3-16-4/h1-3,12H,(H,14,15)(H,10,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving manganese chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183498 (5,6-dihydroxy-2-(3-{[(2-phenyl-1H-indol-3-yl)acety...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)Cc1c([nH]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C25H18N4O5S/c30-18(12-15-14-8-4-5-9-16(14)27-19(15)13-6-2-1-3-7-13)26-17-10-11-35-22(17)23-28-20(25(33)34)21(31)24(32)29-23/h1-11,27,31H,12H2,(H,26,30)(H,33,34)(H,28,29,32)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183502 (2-(3-{[(benzyloxy)carbonyl]amino}-2-thienyl)-5,6-d...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)OCc1ccccc1 Show InChI InChI=1S/C17H13N3O6S/c21-12-11(16(23)24)19-14(20-15(12)22)13-10(6-7-27-13)18-17(25)26-8-9-4-2-1-3-5-9/h1-7,21H,8H2,(H,18,25)(H,23,24)(H,19,20,22)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183487 (2-[3-({[(2-chlorobenzyl)oxy]carbonyl}amino)-2-thie...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)OCc1ccccc1Cl Show InChI InChI=1S/C17H12ClN3O6S/c18-9-4-2-1-3-8(9)7-27-17(26)19-10-5-6-28-13(10)14-20-11(16(24)25)12(22)15(23)21-14/h1-6,22H,7H2,(H,19,26)(H,24,25)(H,20,21,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55-R158M mutant RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183514 (5,6-dihydroxy-2-{3-[(phenylacetyl)amino]-2-thienyl...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)Cc1ccccc1 Show InChI InChI=1S/C17H13N3O5S/c21-11(8-9-4-2-1-3-5-9)18-10-6-7-26-14(10)15-19-12(17(24)25)13(22)16(23)20-15/h1-7,22H,8H2,(H,18,21)(H,24,25)(H,19,20,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50153254 (5,6-dihydroxy-1-methyl-2-thiophen-2-yl-pyrimidine-...) Show SMILES Cn1c(nc(C(O)=O)c(O)c1=O)-c1cccs1 Show InChI InChI=1S/C10H8N2O4S/c1-12-8(5-3-2-4-17-5)11-6(10(15)16)7(13)9(12)14/h2-4,13H,1H3,(H,15,16)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving manganese chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183479 (5,6-dihydroxy-2-{3-[(3-phenylpropanoyl)amino]-2-th...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)CCc1ccccc1 Show InChI InChI=1S/C18H15N3O5S/c22-12(7-6-10-4-2-1-3-5-10)19-11-8-9-27-15(11)16-20-13(18(25)26)14(23)17(24)21-16/h1-5,8-9,23H,6-7H2,(H,19,22)(H,25,26)(H,20,21,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183490 (5,6-dihydroxy-2-[3-({[(2-phenylethyl)amino]carbony...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)NCCc1ccccc1 Show InChI InChI=1S/C18H16N4O5S/c23-13-12(17(25)26)21-15(22-16(13)24)14-11(7-9-28-14)20-18(27)19-8-6-10-4-2-1-3-5-10/h1-5,7,9,23H,6,8H2,(H,25,26)(H2,19,20,27)(H,21,22,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183509 (5,6-dihydroxy-2-(3-nitro-2-thienyl)pyrimidine-4-ca...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1[N+]([O-])=O Show InChI InChI=1S/C9H5N3O6S/c13-5-4(9(15)16)10-7(11-8(5)14)6-3(12(17)18)1-2-19-6/h1-2,13H,(H,15,16)(H,10,11,14)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183509 (5,6-dihydroxy-2-(3-nitro-2-thienyl)pyrimidine-4-ca...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1[N+]([O-])=O Show InChI InChI=1S/C9H5N3O6S/c13-5-4(9(15)16)10-7(11-8(5)14)6-3(12(17)18)1-2-19-6/h1-2,13H,(H,15,16)(H,10,11,14)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving magnesium chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183486 (5,6-dihydroxy-2-(1,3-thiazol-2-yl)pyrimidine-4-car...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1nccs1 Show InChI InChI=1S/C8H5N3O4S/c12-4-3(8(14)15)10-5(11-6(4)13)7-9-1-2-16-7/h1-2,12H,(H,14,15)(H,10,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183486 (5,6-dihydroxy-2-(1,3-thiazol-2-yl)pyrimidine-4-car...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1nccs1 Show InChI InChI=1S/C8H5N3O4S/c12-4-3(8(14)15)10-5(11-6(4)13)7-9-1-2-16-7/h1-2,12H,(H,14,15)(H,10,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving magnesium chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183487 (2-[3-({[(2-chlorobenzyl)oxy]carbonyl}amino)-2-thie...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)OCc1ccccc1Cl Show InChI InChI=1S/C17H12ClN3O6S/c18-9-4-2-1-3-8(9)7-27-17(26)19-10-5-6-28-13(10)14-20-11(16(24)25)12(22)15(23)21-14/h1-6,22H,7H2,(H,19,26)(H,24,25)(H,20,21,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55-R158K mutant RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183482 (2-[3-({[(2-chlorobenzyl)amino]carbonyl}amino)-2-th...) Show SMILES Cn1c(nc(C(O)=O)c(O)c1=O)-c1sccc1NC(=O)Nc1ccccc1Cl Show InChI InChI=1S/C17H13ClN4O5S/c1-22-14(21-11(16(25)26)12(23)15(22)24)13-10(6-7-28-13)20-17(27)19-9-5-3-2-4-8(9)18/h2-7,23H,1H3,(H,25,26)(H2,19,20,27)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving magnesium chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183482 (2-[3-({[(2-chlorobenzyl)amino]carbonyl}amino)-2-th...) Show SMILES Cn1c(nc(C(O)=O)c(O)c1=O)-c1sccc1NC(=O)Nc1ccccc1Cl Show InChI InChI=1S/C17H13ClN4O5S/c1-22-14(21-11(16(25)26)12(23)15(22)24)13-10(6-7-28-13)20-17(27)19-9-5-3-2-4-8(9)18/h2-7,23H,1H3,(H,25,26)(H2,19,20,27)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183512 (5,6-dihydroxy-2-{3-[(2-naphthylsulfonyl)amino]-2-t...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NS(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C19H13N3O6S2/c23-15-14(19(25)26)20-17(21-18(15)24)16-13(7-8-29-16)22-30(27,28)12-6-5-10-3-1-2-4-11(10)9-12/h1-9,22-23H,(H,25,26)(H,20,21,24)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183489 ((3-amino-2-thienyl)-5,6-dihydroxypyrimidine-4-carb...) Show SMILES Nc1ccsc1-c1nc(C(O)=O)c(O)c(=O)[nH]1 Show InChI InChI=1S/C9H7N3O4S/c10-3-1-2-17-6(3)7-11-4(9(15)16)5(13)8(14)12-7/h1-2,13H,10H2,(H,15,16)(H,11,12,14)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM33414 (CHEMBL440562 | pyrimidinol carboxylic acid, 6) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1ccccc1 Show InChI InChI=1S/C11H8N2O4/c14-8-7(11(16)17)12-9(13-10(8)15)6-4-2-1-3-5-6/h1-5,14H,(H,16,17)(H,12,13,15)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving manganese chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183507 (5,6-dihydroxy-2-(methylsulfonyl)pyrimidine-4-carbo...) Show SMILES CS(=O)(=O)c1nc(C(O)=O)c(O)c(=O)[nH]1 Show InChI InChI=1S/C6H6N2O6S/c1-15(13,14)6-7-2(5(11)12)3(9)4(10)8-6/h9H,1H3,(H,11,12)(H,7,8,10)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cccs1 Show InChI InChI=1S/C9H6N2O4S/c12-6-5(9(14)15)10-7(11-8(6)13)4-2-1-3-16-4/h1-3,12H,(H,14,15)(H,10,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving magnesium chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cccs1 Show InChI InChI=1S/C9H6N2O4S/c12-6-5(9(14)15)10-7(11-8(6)13)4-2-1-3-16-4/h1-3,12H,(H,14,15)(H,10,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183486 (5,6-dihydroxy-2-(1,3-thiazol-2-yl)pyrimidine-4-car...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1nccs1 Show InChI InChI=1S/C8H5N3O4S/c12-4-3(8(14)15)10-5(11-6(4)13)7-9-1-2-16-7/h1-2,12H,(H,14,15)(H,10,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55-R158M mutant RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183493 (2-(2-furyl)-5,6-dihydroxypyrimidine-4-carboxylic a...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1ccco1 Show InChI InChI=1S/C9H6N2O5/c12-6-5(9(14)15)10-7(11-8(6)13)4-2-1-3-16-4/h1-3,12H,(H,14,15)(H,10,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183493 (2-(2-furyl)-5,6-dihydroxypyrimidine-4-carboxylic a...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1ccco1 Show InChI InChI=1S/C9H6N2O5/c12-6-5(9(14)15)10-7(11-8(6)13)4-2-1-3-16-4/h1-3,12H,(H,14,15)(H,10,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving magnesium chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50153254 (5,6-dihydroxy-1-methyl-2-thiophen-2-yl-pyrimidine-...) Show SMILES Cn1c(nc(C(O)=O)c(O)c1=O)-c1cccs1 Show InChI InChI=1S/C10H8N2O4S/c1-12-8(5-3-2-4-17-5)11-6(10(15)16)7(13)9(12)14/h2-4,13H,1H3,(H,15,16)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving magnesium chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50153254 (5,6-dihydroxy-1-methyl-2-thiophen-2-yl-pyrimidine-...) Show SMILES Cn1c(nc(C(O)=O)c(O)c1=O)-c1cccs1 Show InChI InChI=1S/C10H8N2O4S/c1-12-8(5-3-2-4-17-5)11-6(10(15)16)7(13)9(12)14/h2-4,13H,1H3,(H,15,16)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183503 (5,6-dihydroxy-2-pyrazin-2-ylpyrimidine-4-carboxyli...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cnccn1 Show InChI InChI=1S/C9H6N4O4/c14-6-5(9(16)17)12-7(13-8(6)15)4-3-10-1-2-11-4/h1-3,14H,(H,16,17)(H,12,13,15)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183501 (5,6-dihydroxy-2-(3-methyl-2-thienyl)pyrimidine-4-c...) Show SMILES Cc1ccsc1-c1nc(C(O)=O)c(O)c(=O)[nH]1 Show InChI InChI=1S/C10H8N2O4S/c1-4-2-3-17-7(4)8-11-5(10(15)16)6(13)9(14)12-8/h2-3,13H,1H3,(H,15,16)(H,11,12,14)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183500 (5-hydroxy-1-methyl-2-(3-nitrothien-2-yl)-6-oxo-1,6...) Show SMILES Cn1c(nc(C(O)=O)c(O)c1=O)-c1sccc1[N+]([O-])=O Show InChI InChI=1S/C10H7N3O6S/c1-12-8(7-4(13(18)19)2-3-20-7)11-5(10(16)17)6(14)9(12)15/h2-3,14H,1H3,(H,16,17)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cccs1 Show InChI InChI=1S/C9H6N2O4S/c12-6-5(9(14)15)10-7(11-8(6)13)4-2-1-3-16-4/h1-3,12H,(H,14,15)(H,10,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55-R158M mutant RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183491 (5,6-dihydroxy-2-(4-nitro-2-thienyl)pyrimidine-4-ca...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cc(cs1)[N+]([O-])=O Show InChI InChI=1S/C9H5N3O6S/c13-6-5(9(15)16)10-7(11-8(6)14)4-1-3(2-19-4)12(17)18/h1-2,13H,(H,15,16)(H,10,11,14)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183485 (2-(1-benzothien-2-yl)-5,6-dihydroxypyrimidine-4-ca...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cc2ccccc2s1 Show InChI InChI=1S/C13H8N2O4S/c16-10-9(13(18)19)14-11(15-12(10)17)8-5-6-3-1-2-4-7(6)20-8/h1-5,16H,(H,18,19)(H,14,15,17)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183513 (5,6-dihydroxy-2-{4-[(2-thienylcarbonyl)amino]-2-th...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cc(NC(=O)c2cccs2)cs1 Show InChI InChI=1S/C14H9N3O5S2/c18-10-9(14(21)22)16-11(17-13(10)20)8-4-6(5-24-8)15-12(19)7-2-1-3-23-7/h1-5,18H,(H,15,19)(H,21,22)(H,16,17,20)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183483 (5,6-dihydroxy-2-(5-nitro-2-thienyl)pyrimidine-4-ca...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1ccc(s1)[N+]([O-])=O Show InChI InChI=1S/C9H5N3O6S/c13-6-5(9(15)16)10-7(11-8(6)14)3-1-2-4(19-3)12(17)18/h1-2,13H,(H,15,16)(H,10,11,14)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183486 (5,6-dihydroxy-2-(1,3-thiazol-2-yl)pyrimidine-4-car...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1nccs1 Show InChI InChI=1S/C8H5N3O4S/c12-4-3(8(14)15)10-5(11-6(4)13)7-9-1-2-16-7/h1-2,12H,(H,14,15)(H,10,11,13)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55-R158K mutant RNA polymerase				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50183484 (2-cyclohexyl-5,6-dihydroxypyrimidine-4-carboxylic ...) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)C1CCCCC1 Show InChI InChI=1S/C11H14N2O4/c14-8-7(11(16)17)12-9(13-10(8)15)6-4-2-1-3-5-6/h6,14H,1-5H2,(H,16,17)(H,12,13,15)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
P. Angeletti S.p.A. (Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving manganese chelation				J Med Chem 49: 1693-705 (2006) Article DOI: 10.1021/jm051064t BindingDB Entry DOI: 10.7270/Q2QJ7GWR
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 71 total )  |  Next  |  Last  >>

Jump to: