Compile Data Set for Download or QSAR

Found 23 hits Enz. Inhib. hit(s) with all data for entry = 50010937   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100358 ((S)-3-[(3-Pyridin-4-yl-3-aza-spiro[5.5]undecane-9-...) Show SMILES Cc1ccc(cc1)S(=O)(=O)N[C@@H](CNC(=O)C1CCC2(CC1)CCN(CC2)c1ccncc1)C(O)=O Show InChI InChI=1S/C26H34N4O5S/c1-19-2-4-22(5-3-19)36(34,35)29-23(25(32)33)18-28-24(31)20-6-10-26(11-7-20)12-16-30(17-13-26)21-8-14-27-15-9-21/h2-5,8-9,14-15,20,23,29H,6-7,10-13,16-18H2,1H3,(H,28,31)(H,32,33)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50092126 (2-(3,5-Dimethyl-isoxazole-4-sulfonylamino)-3-[(3-p...) Show SMILES Cc1noc(C)c1S(=O)(=O)N[C@@H](CNC(=O)C1CCC2(CC1)CCN(CC2)c1ccncc1)C(O)=O Show InChI InChI=1S/C24H33N5O6S/c1-16-21(17(2)35-27-16)36(33,34)28-20(23(31)32)15-26-22(30)18-3-7-24(8-4-18)9-13-29(14-10-24)19-5-11-25-12-6-19/h5-6,11-12,18,20,28H,3-4,7-10,13-15H2,1-2H3,(H,26,30)(H,31,32)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100365 ((S)-2-Benzyloxycarbonylamino-3-[(3-pyridin-4-yl-3-...) Show SMILES OC(=O)[C@H](CNC(=O)C1CCC2(CC1)CCN(CC2)c1ccncc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C27H34N4O5/c32-24(29-18-23(25(33)34)30-26(35)36-19-20-4-2-1-3-5-20)21-6-10-27(11-7-21)12-16-31(17-13-27)22-8-14-28-15-9-22/h1-5,8-9,14-15,21,23H,6-7,10-13,16-19H2,(H,29,32)(H,30,35)(H,33,34)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100360 ((S)-2-(Butane-1-sulfonylamino)-3-[(3-pyridin-4-yl-...) Show SMILES CCCCS(=O)(=O)N[C@@H](CNC(=O)C1CCC2(CC1)CCN(CC2)c1ccncc1)C(O)=O Show InChI InChI=1S/C23H36N4O5S/c1-2-3-16-33(31,32)26-20(22(29)30)17-25-21(28)18-4-8-23(9-5-18)10-14-27(15-11-23)19-6-12-24-13-7-19/h6-7,12-13,18,20,26H,2-5,8-11,14-17H2,1H3,(H,25,28)(H,29,30)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100376 ((S)-2-Butoxycarbonylamino-3-[(3-pyridin-4-yl-3-aza...) Show SMILES CCCCOC(=O)N[C@@H](CNC(=O)C1CCC2(CC1)CCN(CC2)c1ccncc1)C(O)=O Show InChI InChI=1S/C24H36N4O5/c1-2-3-16-33-23(32)27-20(22(30)31)17-26-21(29)18-4-8-24(9-5-18)10-14-28(15-11-24)19-6-12-25-13-7-19/h6-7,12-13,18,20H,2-5,8-11,14-17H2,1H3,(H,26,29)(H,27,32)(H,30,31)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100363 (3-{[3-(4-Carbamimidoyl-phenyl)-3-aza-spiro[5.5]und...) Show SMILES NC(=N)c1ccc(cc1)N1CCC2(CCC(CC2)C(=O)NCCC(O)=O)CC1 Show InChI InChI=1S/C21H30N4O3/c22-19(23)15-1-3-17(4-2-15)25-13-10-21(11-14-25)8-5-16(6-9-21)20(28)24-12-7-18(26)27/h1-4,16H,5-14H2,(H3,22,23)(H,24,28)(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100369 ((3-Pyridin-4-yl-3-aza-spiro[5.5]undec-9-ylamino)-a...) Show SMILES OC(=O)CNC1CCC2(CC1)CCN(CC2)c1ccncc1 Show InChI InChI=1S/C17H25N3O2/c21-16(22)13-19-14-1-5-17(6-2-14)7-11-20(12-8-17)15-3-9-18-10-4-15/h3-4,9-10,14,19H,1-2,5-8,11-13H2,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100372 ((3-Pyridin-4-yl-3-aza-spiro[5.5]undec-9-yloxy)-ace...) Show SMILES OC(=O)COC1CCC2(CC1)CCN(CC2)c1ccncc1 Show InChI InChI=1S/C17H24N2O3/c20-16(21)13-22-15-1-5-17(6-2-15)7-11-19(12-8-17)14-3-9-18-10-4-14/h3-4,9-10,15H,1-2,5-8,11-13H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100362 (CHEMBL24671 | [9-(4-Cyclohexyl-piperidine-1-carbon...) Show SMILES OC(=O)CN1CCC2(CCC(CC2)C(=O)N2CCC(CC2)C2CCCCC2)CC1 Show InChI InChI=1S/C24H40N2O3/c27-22(28)18-25-16-12-24(13-17-25)10-6-21(7-11-24)23(29)26-14-8-20(9-15-26)19-4-2-1-3-5-19/h19-21H,1-18H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100373 (4-[(3-Pyridin-4-yl-3-aza-spiro[5.5]undecane-9-carb...) Show SMILES OC(=O)CCCNC(=O)C1CCC2(CC1)CCN(CC2)c1ccncc1 Show InChI InChI=1S/C20H29N3O3/c24-18(25)2-1-11-22-19(26)16-3-7-20(8-4-16)9-14-23(15-10-20)17-5-12-21-13-6-17/h5-6,12-13,16H,1-4,7-11,14-15H2,(H,22,26)(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	319	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100370 (3-Methyl-4-[(3-pyridin-4-yl-3-aza-spiro[5.5]undeca...) Show SMILES CC(CNC(=O)C1CCC2(CC1)CCN(CC2)c1ccncc1)CC(O)=O Show InChI InChI=1S/C21H31N3O3/c1-16(14-19(25)26)15-23-20(27)17-2-6-21(7-3-17)8-12-24(13-9-21)18-4-10-22-11-5-18/h4-5,10-11,16-17H,2-3,6-9,12-15H2,1H3,(H,23,27)(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	332	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100374 (CHEMBL280622 | [9-(4-Pyridin-4-yl-piperazine-1-car...) Show SMILES OC(=O)CN1CCC2(CCC(CC2)C(=O)N2CCN(CC2)c2ccncc2)CC1 Show InChI InChI=1S/C22H32N4O3/c27-20(28)17-24-11-7-22(8-12-24)5-1-18(2-6-22)21(29)26-15-13-25(14-16-26)19-3-9-23-10-4-19/h3-4,9-10,18H,1-2,5-8,11-17H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	364	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100368 ((S)-3-[(3-Pyridin-4-yl-3-aza-spiro[5.5]undecane-9-...) Show SMILES C[C@@H](CC(O)=O)NC(=O)C1CCC2(CC1)CCN(CC2)c1ccncc1 Show InChI InChI=1S/C20H29N3O3/c1-15(14-18(24)25)22-19(26)16-2-6-20(7-3-16)8-12-23(13-9-20)17-4-10-21-11-5-17/h4-5,10-11,15-16H,2-3,6-9,12-14H2,1H3,(H,22,26)(H,24,25)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	616	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100371 ((S)-2-Amino-3-[(3-pyridin-4-yl-3-aza-spiro[5.5]und...) Show SMILES N[C@@H](CNC(=O)C1CCC2(CC1)CCN(CC2)c1ccncc1)C(O)=O Show InChI InChI=1S/C19H28N4O3/c20-16(18(25)26)13-22-17(24)14-1-5-19(6-2-14)7-11-23(12-8-19)15-3-9-21-10-4-15/h3-4,9-10,14,16H,1-2,5-8,11-13,20H2,(H,22,24)(H,25,26)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100379 (3-[9-([4,4']Bipiperidinyl-1-carbonyl)-3-aza-spiro[...) Show SMILES OC(=O)CC(=O)N1CCC2(CCC(CC2)C(=O)N2CCC(CC2)C2CCNCC2)CC1 Show InChI InChI=1S/C24H39N3O4/c28-21(17-22(29)30)26-15-9-24(10-16-26)7-1-20(2-8-24)23(31)27-13-5-19(6-14-27)18-3-11-25-12-4-18/h18-20,25H,1-17H2,(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100364 (3-[9-(4-Pyridin-4-yl-piperazine-1-carbonyl)-3-aza-...) Show SMILES OC(=O)CCN1CCC2(CCC(CC2)C(=O)N2CCN(CC2)c2ccncc2)CC1 Show InChI InChI=1S/C23H34N4O3/c28-21(29)5-12-25-13-8-23(9-14-25)6-1-19(2-7-23)22(30)27-17-15-26(16-18-27)20-3-10-24-11-4-20/h3-4,10-11,19H,1-2,5-9,12-18H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100377 (4-{[3-(4-Carbamimidoyl-phenyl)-3-aza-spiro[5.5]und...) Show SMILES NC(=N)c1ccc(cc1)N1CCC2(CCC(CC2)C(=O)NCCCC(O)=O)CC1 Show InChI InChI=1S/C22H32N4O3/c23-20(24)16-3-5-18(6-4-16)26-14-11-22(12-15-26)9-7-17(8-10-22)21(29)25-13-1-2-19(27)28/h3-6,17H,1-2,7-15H2,(H3,23,24)(H,25,29)(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100359 (CHEMBL24718 | {[3-(4-Carbamimidoyl-benzoyl)-3-aza-...) Show SMILES NC(=N)c1ccc(cc1)C(=O)N1CCC2(CCC(CC2)C(=O)NCC(O)=O)CC1 Show InChI InChI=1S/C21H28N4O4/c22-18(23)14-1-3-16(4-2-14)20(29)25-11-9-21(10-12-25)7-5-15(6-8-21)19(28)24-13-17(26)27/h1-4,15H,5-13H2,(H3,22,23)(H,24,28)(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100367 (3-(4-Carbamimidoyl-benzoyl)-3-aza-spiro[5.5]undeca...) Show SMILES NC(=N)c1ccc(cc1)C(=O)N1CCC2(CCC(CC2)C(O)=O)CC1 Show InChI InChI=1S/C19H25N3O3/c20-16(21)13-1-3-14(4-2-13)17(23)22-11-9-19(10-12-22)7-5-15(6-8-19)18(24)25/h1-4,15H,5-12H2,(H3,20,21)(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100375 ((R)-3-Phenyl-3-[(3-pyridin-4-yl-3-aza-spiro[5.5]un...) Show SMILES OC(=O)C[C@@H](NC(=O)C1CCC2(CC1)CCN(CC2)c1ccncc1)c1ccccc1 Show InChI InChI=1S/C25H31N3O3/c29-23(30)18-22(19-4-2-1-3-5-19)27-24(31)20-6-10-25(11-7-20)12-16-28(17-13-25)21-8-14-26-15-9-21/h1-5,8-9,14-15,20,22H,6-7,10-13,16-18H2,(H,27,31)(H,29,30)/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100366 (3-(3-Pyridin-4-yl-3-aza-spiro[5.5]undec-9-ylamino)...) Show SMILES OC(=O)CCNC1CCC2(CC1)CCN(CC2)c1ccncc1 Show InChI InChI=1S/C18H27N3O2/c22-17(23)5-12-20-15-1-6-18(7-2-15)8-13-21(14-9-18)16-3-10-19-11-4-16/h3-4,10-11,15,20H,1-2,5-9,12-14H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100378 (4-[9-([4,4']Bipiperidinyl-1-carbonyl)-3-aza-spiro[...) Show SMILES OC(=O)CCC(=O)N1CCC2(CCC(CC2)C(=O)N2CCC(CC2)C2CCNCC2)CC1 Show InChI InChI=1S/C25H41N3O4/c29-22(1-2-23(30)31)27-17-11-25(12-18-27)9-3-21(4-10-25)24(32)28-15-7-20(8-16-28)19-5-13-26-14-6-19/h19-21,26H,1-18H2,(H,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50100361 (5-[9-([4,4']Bipiperidinyl-1-carbonyl)-3-aza-spiro[...) Show SMILES OC(=O)CCCC(=O)N1CCC2(CCC(CC2)C(=O)N2CCC(CC2)C2CCNCC2)CC1 Show InChI InChI=1S/C26H43N3O4/c30-23(2-1-3-24(31)32)28-18-12-26(13-19-28)10-4-22(5-11-26)25(33)29-16-8-21(9-17-29)20-6-14-27-15-7-20/h20-22,27H,1-19H2,(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
COR Therapeutics, Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa				Bioorg Med Chem Lett 11: 1293-6 (2001) BindingDB Entry DOI: 10.7270/Q2Z037DQ
					More data for this Ligand-Target Pair