Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387062 (CHEMBL2047041) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387054 (CHEMBL2047033) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387062 (CHEMBL2047041) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387056 (CHEMBL2047034) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387057 (CHEMBL2047039) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387057 (CHEMBL2047039) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387064 (CHEMBL2047038) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387054 (CHEMBL2047033) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387056 (CHEMBL2047034) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387065 (CHEMBL2047037) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387064 (CHEMBL2047038) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387065 (CHEMBL2047037) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387053 (CHEMBL2047035) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387058 (CHEMBL2047045) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387058 (CHEMBL2047045) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387053 (CHEMBL2047035) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387060 (CHEMBL2047043) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387063 (CHEMBL2047040) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387055 (CHEMBL2047032) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387063 (CHEMBL2047040) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387060 (CHEMBL2047043) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387055 (CHEMBL2047032) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387059 (CHEMBL2047044) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387059 (CHEMBL2047044) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387052 (CHEMBL2047036) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387061 (CHEMBL2047042) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387052 (CHEMBL2047036) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50387061 (CHEMBL2047042) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Link£ping University Curated by ChEMBL | Assay Description Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by... | Bioorg Med Chem 20: 4377-89 (2012) Article DOI: 10.1016/j.bmc.2012.05.039 BindingDB Entry DOI: 10.7270/Q2N29Z06 | |||||||||||
More data for this Ligand-Target Pair |