Compile Data Set for Download or QSAR

Found 62 hits Enz. Inhib. hit(s) with all data for entry = 50044756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028695 (CHEMBL3342688) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1c[nH]c(n1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C23H26N6O3/c24-23(25)26-13-7-12-17(22(31)32)29-21(30)18-14-27-20(28-18)19(15-8-3-1-4-9-15)16-10-5-2-6-11-16/h1-6,8-11,14,17,19H,7,12-13H2,(H,27,28)(H,29,30)(H,31,32)(H4,24,25,26)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028695 (CHEMBL3342688) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1c[nH]c(n1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C23H26N6O3/c24-23(25)26-13-7-12-17(22(31)32)29-21(30)18-14-27-20(28-18)19(15-8-3-1-4-9-15)16-10-5-2-6-11-16/h1-6,8-11,14,17,19H,7,12-13H2,(H,27,28)(H,29,30)(H,31,32)(H4,24,25,26)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028698 (CHEMBL3342676) Show SMILES NC(=N)NCCC[C@H](NC(=O)CSCC(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H28N4O3S/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19H,7,12-15H2,(H,26,27)(H,28,29)(H4,23,24,25)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028698 (CHEMBL3342676) Show SMILES NC(=N)NCCC[C@H](NC(=O)CSCC(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H28N4O3S/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19H,7,12-15H2,(H,26,27)(H,28,29)(H4,23,24,25)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028781 (CHEMBL3342686) Show SMILES Cc1oc(nc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H27N5O4/c1-15-20(21(30)28-18(23(31)32)13-8-14-27-24(25)26)29-22(33-15)19(16-9-4-2-5-10-16)17-11-6-3-7-12-17/h2-7,9-12,18-19H,8,13-14H2,1H3,(H,28,30)(H,31,32)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50322650 ((S)-2-(2-(2,2-diphenylethoxy)acetamido)-5-guanidin...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#8]-[#6]-[#6](-c1ccccc1)-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C22H28N4O4/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19H,7,12-15H2,(H,26,27)(H,28,29)(H4,23,24,25)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50322650 ((S)-2-(2-(2,2-diphenylethoxy)acetamido)-5-guanidin...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#8]-[#6]-[#6](-c1ccccc1)-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C22H28N4O4/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19H,7,12-15H2,(H,26,27)(H,28,29)(H4,23,24,25)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028696 (CHEMBL3342689) Show SMILES Cc1[nH]c(nc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H28N6O3/c1-15-20(22(31)29-18(23(32)33)13-8-14-27-24(25)26)30-21(28-15)19(16-9-4-2-5-10-16)17-11-6-3-7-12-17/h2-7,9-12,18-19H,8,13-14H2,1H3,(H,28,30)(H,29,31)(H,32,33)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028696 (CHEMBL3342689) Show SMILES Cc1[nH]c(nc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H28N6O3/c1-15-20(22(31)29-18(23(32)33)13-8-14-27-24(25)26)30-21(28-15)19(16-9-4-2-5-10-16)17-11-6-3-7-12-17/h2-7,9-12,18-19H,8,13-14H2,1H3,(H,28,30)(H,29,31)(H,32,33)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028781 (CHEMBL3342686) Show SMILES Cc1oc(nc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H27N5O4/c1-15-20(21(30)28-18(23(31)32)13-8-14-27-24(25)26)29-22(33-15)19(16-9-4-2-5-10-16)17-11-6-3-7-12-17/h2-7,9-12,18-19H,8,13-14H2,1H3,(H,28,30)(H,31,32)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028702 (CHEMBL3342680) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1nc(no1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H24N6O4/c23-22(24)25-13-7-12-16(21(30)31)26-19(29)20-27-18(28-32-20)17(14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16-17H,7,12-13H2,(H,26,29)(H,30,31)(H4,23,24,25)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028702 (CHEMBL3342680) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1nc(no1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H24N6O4/c23-22(24)25-13-7-12-16(21(30)31)26-19(29)20-27-18(28-32-20)17(14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16-17H,7,12-13H2,(H,26,29)(H,30,31)(H4,23,24,25)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028780 (CHEMBL3342685) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1coc(n1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C23H25N5O4/c24-23(25)26-13-7-12-17(22(30)31)27-20(29)18-14-32-21(28-18)19(15-8-3-1-4-9-15)16-10-5-2-6-11-16/h1-6,8-11,14,17,19H,7,12-13H2,(H,27,29)(H,30,31)(H4,24,25,26)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028780 (CHEMBL3342685) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1coc(n1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C23H25N5O4/c24-23(25)26-13-7-12-17(22(30)31)27-20(29)18-14-32-21(28-18)19(15-8-3-1-4-9-15)16-10-5-2-6-11-16/h1-6,8-11,14,17,19H,7,12-13H2,(H,27,29)(H,30,31)(H4,24,25,26)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028697 (CHEMBL3342690) Show SMILES Cc1c(nc(C(c2ccccc2)c2ccccc2)n1C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| Show InChI InChI=1S/C25H30N6O3/c1-16-21(23(32)29-19(24(33)34)14-9-15-28-25(26)27)30-22(31(16)2)20(17-10-5-3-6-11-17)18-12-7-4-8-13-18/h3-8,10-13,19-20H,9,14-15H2,1-2H3,(H,29,32)(H,33,34)(H4,26,27,28)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028697 (CHEMBL3342690) Show SMILES Cc1c(nc(C(c2ccccc2)c2ccccc2)n1C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| Show InChI InChI=1S/C25H30N6O3/c1-16-21(23(32)29-19(24(33)34)14-9-15-28-25(26)27)30-22(31(16)2)20(17-10-5-3-6-11-17)18-12-7-4-8-13-18/h3-8,10-13,19-20H,9,14-15H2,1-2H3,(H,29,32)(H,33,34)(H4,26,27,28)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028775 (CHEMBL3342681) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1noc(n1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H24N6O4/c23-22(24)25-13-7-12-16(21(30)31)26-19(29)18-27-20(32-28-18)17(14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16-17H,7,12-13H2,(H,26,29)(H,30,31)(H4,23,24,25)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422988 (CHEMBL230034) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1ccc(o1)-[#6](-c1ccccc1)-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C24H26N4O4/c25-24(26)27-15-7-12-18(23(30)31)28-22(29)20-14-13-19(32-20)21(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,13-14,18,21H,7,12,15H2,(H,28,29)(H,30,31)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028775 (CHEMBL3342681) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1noc(n1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H24N6O4/c23-22(24)25-13-7-12-16(21(30)31)26-19(29)18-27-20(32-28-18)17(14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16-17H,7,12-13H2,(H,26,29)(H,30,31)(H4,23,24,25)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422988 (CHEMBL230034) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1ccc(o1)-[#6](-c1ccccc1)-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C24H26N4O4/c25-24(26)27-15-7-12-18(23(30)31)28-22(29)20-14-13-19(32-20)21(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,13-14,18,21H,7,12,15H2,(H,28,29)(H,30,31)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028778 (CHEMBL3342687) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1nc([nH]c1-c1ccccc1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C29H30N6O3/c30-29(31)32-18-10-17-22(28(37)38)33-27(36)25-24(21-15-8-3-9-16-21)34-26(35-25)23(19-11-4-1-5-12-19)20-13-6-2-7-14-20/h1-9,11-16,22-23H,10,17-18H2,(H,33,36)(H,34,35)(H,37,38)(H4,30,31,32)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028778 (CHEMBL3342687) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1nc([nH]c1-c1ccccc1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C29H30N6O3/c30-29(31)32-18-10-17-22(28(37)38)33-27(36)25-24(21-15-8-3-9-16-21)34-26(35-25)23(19-11-4-1-5-12-19)20-13-6-2-7-14-20/h1-9,11-16,22-23H,10,17-18H2,(H,33,36)(H,34,35)(H,37,38)(H4,30,31,32)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028699 (CHEMBL3342677) Show SMILES NC(=N)NCCC[C@H](NC(=O)CCCC(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C23H30N4O3/c24-23(25)26-16-8-14-20(22(29)30)27-21(28)15-7-13-19(17-9-3-1-4-10-17)18-11-5-2-6-12-18/h1-6,9-12,19-20H,7-8,13-16H2,(H,27,28)(H,29,30)(H4,24,25,26)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028777 (CHEMBL3342683) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1oc(nc1-c1ccccc1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C29H29N5O4/c30-29(31)32-18-10-17-22(28(36)37)33-26(35)25-24(21-15-8-3-9-16-21)34-27(38-25)23(19-11-4-1-5-12-19)20-13-6-2-7-14-20/h1-9,11-16,22-23H,10,17-18H2,(H,33,35)(H,36,37)(H4,30,31,32)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028701 (CHEMBL3342679) Show SMILES Cc1nc(oc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H27N5O4/c1-15-20(21(30)29-18(23(31)32)13-8-14-27-24(25)26)33-22(28-15)19(16-9-4-2-5-10-16)17-11-6-3-7-12-17/h2-7,9-12,18-19H,8,13-14H2,1H3,(H,29,30)(H,31,32)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028699 (CHEMBL3342677) Show SMILES NC(=N)NCCC[C@H](NC(=O)CCCC(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C23H30N4O3/c24-23(25)26-16-8-14-20(22(29)30)27-21(28)15-7-13-19(17-9-3-1-4-10-17)18-11-5-2-6-12-18/h1-6,9-12,19-20H,7-8,13-16H2,(H,27,28)(H,29,30)(H4,24,25,26)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028701 (CHEMBL3342679) Show SMILES Cc1nc(oc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H27N5O4/c1-15-20(21(30)29-18(23(31)32)13-8-14-27-24(25)26)33-22(28-15)19(16-9-4-2-5-10-16)17-11-6-3-7-12-17/h2-7,9-12,18-19H,8,13-14H2,1H3,(H,29,30)(H,31,32)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028777 (CHEMBL3342683) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1oc(nc1-c1ccccc1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C29H29N5O4/c30-29(31)32-18-10-17-22(28(36)37)33-26(35)25-24(21-15-8-3-9-16-21)34-27(38-25)23(19-11-4-1-5-12-19)20-13-6-2-7-14-20/h1-9,11-16,22-23H,10,17-18H2,(H,33,35)(H,36,37)(H4,30,31,32)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028700 (CHEMBL3342678) Show SMILES NC(=N)NCCC[C@H](NC(=O)CNCC(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H29N5O3/c23-22(24)26-13-7-12-19(21(29)30)27-20(28)15-25-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19,25H,7,12-15H2,(H,27,28)(H,29,30)(H4,23,24,26)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028700 (CHEMBL3342678) Show SMILES NC(=N)NCCC[C@H](NC(=O)CNCC(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H29N5O3/c23-22(24)26-13-7-12-19(21(29)30)27-20(28)15-25-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19,25H,7,12-15H2,(H,27,28)(H,29,30)(H4,23,24,26)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028698 (CHEMBL3342676) Show SMILES NC(=N)NCCC[C@H](NC(=O)CSCC(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H28N4O3S/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19H,7,12-15H2,(H,26,27)(H,28,29)(H4,23,24,25)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028698 (CHEMBL3342676) Show SMILES NC(=N)NCCC[C@H](NC(=O)CSCC(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H28N4O3S/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19H,7,12-15H2,(H,26,27)(H,28,29)(H4,23,24,25)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028776 (CHEMBL3342682) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1nnc(o1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H24N6O4/c23-22(24)25-13-7-12-16(21(30)31)26-18(29)20-28-27-19(32-20)17(14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16-17H,7,12-13H2,(H,26,29)(H,30,31)(H4,23,24,25)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	967	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028702 (CHEMBL3342680) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1nc(no1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H24N6O4/c23-22(24)25-13-7-12-16(21(30)31)26-19(29)20-27-18(28-32-20)17(14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16-17H,7,12-13H2,(H,26,29)(H,30,31)(H4,23,24,25)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	999	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028775 (CHEMBL3342681) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1noc(n1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H24N6O4/c23-22(24)25-13-7-12-16(21(30)31)26-19(29)18-27-20(32-28-18)17(14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16-17H,7,12-13H2,(H,26,29)(H,30,31)(H4,23,24,25)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	999	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028702 (CHEMBL3342680) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1nc(no1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H24N6O4/c23-22(24)25-13-7-12-16(21(30)31)26-19(29)20-27-18(28-32-20)17(14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16-17H,7,12-13H2,(H,26,29)(H,30,31)(H4,23,24,25)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028776 (CHEMBL3342682) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1nnc(o1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H24N6O4/c23-22(24)25-13-7-12-16(21(30)31)26-18(29)20-28-27-19(32-20)17(14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16-17H,7,12-13H2,(H,26,29)(H,30,31)(H4,23,24,25)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028775 (CHEMBL3342681) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1noc(n1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H24N6O4/c23-22(24)25-13-7-12-16(21(30)31)26-19(29)18-27-20(32-28-18)17(14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16-17H,7,12-13H2,(H,26,29)(H,30,31)(H4,23,24,25)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028779 (CHEMBL3342684) Show SMILES Cc1nc(C(c2ccccc2)c2ccccc2)n(C)c1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| Show InChI InChI=1S/C25H30N6O3/c1-16-21(23(32)30-19(24(33)34)14-9-15-28-25(26)27)31(2)22(29-16)20(17-10-5-3-6-11-17)18-12-7-4-8-13-18/h3-8,10-13,19-20H,9,14-15H2,1-2H3,(H,30,32)(H,33,34)(H4,26,27,28)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50322650 ((S)-2-(2-(2,2-diphenylethoxy)acetamido)-5-guanidin...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#8]-[#6]-[#6](-c1ccccc1)-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C22H28N4O4/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19H,7,12-15H2,(H,26,27)(H,28,29)(H4,23,24,25)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50322650 ((S)-2-(2-(2,2-diphenylethoxy)acetamido)-5-guanidin...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#8]-[#6]-[#6](-c1ccccc1)-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C22H28N4O4/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19H,7,12-15H2,(H,26,27)(H,28,29)(H4,23,24,25)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028779 (CHEMBL3342684) Show SMILES Cc1nc(C(c2ccccc2)c2ccccc2)n(C)c1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| Show InChI InChI=1S/C25H30N6O3/c1-16-21(23(32)30-19(24(33)34)14-9-15-28-25(26)27)31(2)22(29-16)20(17-10-5-3-6-11-17)18-12-7-4-8-13-18/h3-8,10-13,19-20H,9,14-15H2,1-2H3,(H,30,32)(H,33,34)(H4,26,27,28)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422988 (CHEMBL230034) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1ccc(o1)-[#6](-c1ccccc1)-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C24H26N4O4/c25-24(26)27-15-7-12-18(23(30)31)28-22(29)20-14-13-19(32-20)21(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,13-14,18,21H,7,12,15H2,(H,28,29)(H,30,31)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028777 (CHEMBL3342683) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1oc(nc1-c1ccccc1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C29H29N5O4/c30-29(31)32-18-10-17-22(28(36)37)33-26(35)25-24(21-15-8-3-9-16-21)34-27(38-25)23(19-11-4-1-5-12-19)20-13-6-2-7-14-20/h1-9,11-16,22-23H,10,17-18H2,(H,33,35)(H,36,37)(H4,30,31,32)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422988 (CHEMBL230034) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1ccc(o1)-[#6](-c1ccccc1)-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C24H26N4O4/c25-24(26)27-15-7-12-18(23(30)31)28-22(29)20-14-13-19(32-20)21(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,13-14,18,21H,7,12,15H2,(H,28,29)(H,30,31)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028777 (CHEMBL3342683) Show SMILES NC(=N)NCCC[C@H](NC(=O)c1oc(nc1-c1ccccc1)C(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C29H29N5O4/c30-29(31)32-18-10-17-22(28(36)37)33-26(35)25-24(21-15-8-3-9-16-21)34-27(38-25)23(19-11-4-1-5-12-19)20-13-6-2-7-14-20/h1-9,11-16,22-23H,10,17-18H2,(H,33,35)(H,36,37)(H4,30,31,32)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028700 (CHEMBL3342678) Show SMILES NC(=N)NCCC[C@H](NC(=O)CNCC(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H29N5O3/c23-22(24)26-13-7-12-19(21(29)30)27-20(28)15-25-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19,25H,7,12-15H2,(H,27,28)(H,29,30)(H4,23,24,26)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028701 (CHEMBL3342679) Show SMILES Cc1nc(oc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H27N5O4/c1-15-20(21(30)29-18(23(31)32)13-8-14-27-24(25)26)33-22(28-15)19(16-9-4-2-5-10-16)17-11-6-3-7-12-17/h2-7,9-12,18-19H,8,13-14H2,1H3,(H,29,30)(H,31,32)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028700 (CHEMBL3342678) Show SMILES NC(=N)NCCC[C@H](NC(=O)CNCC(c1ccccc1)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H29N5O3/c23-22(24)26-13-7-12-19(21(29)30)27-20(28)15-25-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19,25H,7,12-15H2,(H,27,28)(H,29,30)(H4,23,24,26)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50028701 (CHEMBL3342679) Show SMILES Cc1nc(oc1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H27N5O4/c1-15-20(21(30)29-18(23(31)32)13-8-14-27-24(25)26)33-22(28-15)19(16-9-4-2-5-10-16)17-11-6-3-7-12-17/h2-7,9-12,18-19H,8,13-14H2,1H3,(H,29,30)(H,31,32)(H4,25,26,27)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
					More data for this Ligand-Target Pair

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