Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50346864 (CHEMBL1797641 | CHEMBL3104337 | US8765820, 8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of LSD1 (unknown origin) | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50080870 (CHEMBL3421673) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex... | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50080872 (CHEMBL3421675) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex... | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM50080871 (CHEMBL3421672) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines... | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM50080870 (CHEMBL3421673) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines... | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50346864 (CHEMBL1797641 | CHEMBL3104337 | US8765820, 8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex... | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM50080873 (CHEMBL3421674) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines... | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM50080872 (CHEMBL3421675) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines... | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM50346864 (CHEMBL1797641 | CHEMBL3104337 | US8765820, 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines... | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50080871 (CHEMBL3421672) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex... | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific histone demethylase 1A (Homo sapiens (Human)) | BDBM50080873 (CHEMBL3421674) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex... | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50080870 (CHEMBL3421673) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOB expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines... | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50080871 (CHEMBL3421672) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza University of Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOB expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines... | ACS Med Chem Lett 6: 173-7 (2015) Article DOI: 10.1021/ml500424z BindingDB Entry DOI: 10.7270/Q2833TQM | |||||||||||
More data for this Ligand-Target Pair |