Compile Data Set for Download or QSAR

Found 136 hits Enz. Inhib. hit(s) with all data for entry = 50046050   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092618 (CHEMBL3586362) Show SMILES C[C@@H]1COc2c(Cl)cc(cc2CN1Cc1cc[nH]c(=O)c1)-n1ccc2cc(F)ccc12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM50092616 (CHEMBL3586360) Show SMILES Fc1ccc2n(ccc2c1)-c1cc(Cl)c2OCCN(Cc3cc[nH]c(=O)c3)Cc2c1 Show InChI InChI=1S/C23H19ClFN3O2/c24-20-12-19(28-6-4-16-10-18(25)1-2-21(16)28)11-17-14-27(7-8-30-23(17)20)13-15-3-5-26-22(29)9-15/h1-6,9-12H,7-8,13-14H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at mouse EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092616 (CHEMBL3586360) Show SMILES Fc1ccc2n(ccc2c1)-c1cc(Cl)c2OCCN(Cc3cc[nH]c(=O)c3)Cc2c1 Show InChI InChI=1S/C23H19ClFN3O2/c24-20-12-19(28-6-4-16-10-18(25)1-2-21(16)28)11-17-14-27(7-8-30-23(17)20)13-15-3-5-26-22(29)9-15/h1-6,9-12H,7-8,13-14H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092615 (CHEMBL3586361) Show SMILES C[C@@H]1COc2c(Cl)cc(cc2CN1Cc1cc[nH]c(=O)c1)-c1csc2ccccc12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM50092616 (CHEMBL3586360) Show SMILES Fc1ccc2n(ccc2c1)-c1cc(Cl)c2OCCN(Cc3cc[nH]c(=O)c3)Cc2c1 Show InChI InChI=1S/C23H19ClFN3O2/c24-20-12-19(28-6-4-16-10-18(25)1-2-21(16)28)11-17-14-27(7-8-30-23(17)20)13-15-3-5-26-22(29)9-15/h1-6,9-12H,7-8,13-14H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092618 (CHEMBL3586362) Show SMILES C[C@@H]1COc2c(Cl)cc(cc2CN1Cc1cc[nH]c(=O)c1)-n1ccc2cc(F)ccc12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Rattus norvegicus)	BDBM50092616 (CHEMBL3586360) Show SMILES Fc1ccc2n(ccc2c1)-c1cc(Cl)c2OCCN(Cc3cc[nH]c(=O)c3)Cc2c1 Show InChI InChI=1S/C23H19ClFN3O2/c24-20-12-19(28-6-4-16-10-18(25)1-2-21(16)28)11-17-14-27(7-8-30-23(17)20)13-15-3-5-26-22(29)9-15/h1-6,9-12H,7-8,13-14H2,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from rat EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092760 (CHEMBL3586312) Show SMILES COc1cc(cc2CN(Cc3cncnc3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C21H25FN2/c1-16-13-19(22)7-8-21(16)24-11-9-23(10-12-24)15-18-14-20(18)17-5-3-2-4-6-17/h2-8,13,18,20H,9-12,14-15H2,1H3/t18-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092619 (CHEMBL3586359) Show SMILES Clc1cc(cc2CN(Cc3cc[nH]c(=O)c3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C23H19ClN2O2S/c24-20-11-16(19-14-29-21-4-2-1-3-18(19)21)10-17-13-26(7-8-28-23(17)20)12-15-5-6-25-22(27)9-15/h1-6,9-11,14H,7-8,12-13H2,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092653 (CHEMBL3586347) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)N1CCc2cc(Cl)ccc12 Show InChI InChI=1S/C24H24ClN3O2/c1-29-23-13-21(28-8-6-18-11-20(25)4-5-22(18)28)12-19-16-27(9-10-30-24(19)23)15-17-3-2-7-26-14-17/h2-5,7,11-14H,6,8-10,15-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Rattus norvegicus)	BDBM50092616 (CHEMBL3586360) Show SMILES Fc1ccc2n(ccc2c1)-c1cc(Cl)c2OCCN(Cc3cc[nH]c(=O)c3)Cc2c1 Show InChI InChI=1S/C23H19ClFN3O2/c24-20-12-19(28-6-4-16-10-18(25)1-2-21(16)28)11-17-14-27(7-8-30-23(17)20)13-15-3-5-26-22(29)9-15/h1-6,9-12H,7-8,13-14H2,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092654 (CHEMBL3586346) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-n1ccc2cc(F)ccc12 Show InChI InChI=1S/C20H21N5O6S/c1-25(9-10-2-3-12-11(8-10)17(28)24-20(21)23-12)15-6-5-14(32-15)18(29)22-13(19(30)31)4-7-16(26)27/h2-3,5-6,8,13H,4,7,9H2,1H3,(H,22,29)(H,26,27)(H,30,31)(H3,21,23,24,28)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092616 (CHEMBL3586360) Show SMILES Fc1ccc2n(ccc2c1)-c1cc(Cl)c2OCCN(Cc3cc[nH]c(=O)c3)Cc2c1 Show InChI InChI=1S/C23H19ClFN3O2/c24-20-12-19(28-6-4-16-10-18(25)1-2-21(16)28)11-17-14-27(7-8-30-23(17)20)13-15-3-5-26-22(29)9-15/h1-6,9-12H,7-8,13-14H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092653 (CHEMBL3586347) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)N1CCc2cc(Cl)ccc12 Show InChI InChI=1S/C24H24ClN3O2/c1-29-23-13-21(28-8-6-18-11-20(25)4-5-22(18)28)12-19-16-27(9-10-30-24(19)23)15-17-3-2-7-26-14-17/h2-5,7,11-14H,6,8-10,15-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM50092617 (CHEMBL3586309) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C24H22N2O2S/c1-27-22-12-18(21-16-29-23-7-3-2-6-20(21)23)11-19-15-26(9-10-28-24(19)22)14-17-5-4-8-25-13-17/h2-8,11-13,16H,9-10,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at mouse EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092725 (CHEMBL3586340) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-n1cc(Cl)c2ccccc12 Show InChI InChI=1S/C24H22ClN3O2/c1-29-23-12-19(28-16-21(25)20-6-2-3-7-22(20)28)11-18-15-27(9-10-30-24(18)23)14-17-5-4-8-26-13-17/h2-8,11-13,16H,9-10,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092617 (CHEMBL3586309) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C24H22N2O2S/c1-27-22-12-18(21-16-29-23-7-3-2-6-20(21)23)11-19-15-26(9-10-28-24(19)22)14-17-5-4-8-25-13-17/h2-8,11-13,16H,9-10,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092760 (CHEMBL3586312) Show SMILES COc1cc(cc2CN(Cc3cncnc3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C21H25FN2/c1-16-13-19(22)7-8-21(16)24-11-9-23(10-12-24)15-18-14-20(18)17-5-3-2-4-6-17/h2-8,13,18,20H,9-12,14-15H2,1H3/t18-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092723 (CHEMBL3586342) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-n1ccc2cc(Cl)ccc12 Show InChI InChI=1S/C24H22ClN3O2/c1-29-23-13-21(28-8-6-18-11-20(25)4-5-22(18)28)12-19-16-27(9-10-30-24(19)23)15-17-3-2-7-26-14-17/h2-8,11-14H,9-10,15-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092638 (CHEMBL3586353) Show SMILES Clc1cc(cc2CN(Cc3cccnc3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C79H100FN17O19S2/c1-42(85-64(102)37-82)67(103)94-61-40-117-118-41-62(79(115)116)95-75(111)60(39-98)93-78(114)66(44(3)100)97-74(110)57(33-47-21-11-6-12-22-47)92-77(113)65(43(2)99)96-73(109)56(34-48-26-28-50(80)29-27-48)89-71(107)58(35-49-38-84-52-24-14-13-23-51(49)52)90-70(106)55(32-46-19-9-5-10-20-46)87-69(105)54(31-45-17-7-4-8-18-45)88-72(108)59(36-63(83)101)91-68(104)53(86-76(61)112)25-15-16-30-81/h4-14,17-24,26-29,38,42-44,53-62,65-66,84,98-100H,15-16,25,30-37,39-41,81-82H2,1-3H3,(H2,83,101)(H,85,102)(H,86,112)(H,87,105)(H,88,108)(H,89,107)(H,90,106)(H,91,104)(H,92,113)(H,93,114)(H,94,103)(H,95,111)(H,96,109)(H,97,110)(H,115,116)/t42?,43?,44?,53-,54-,55-,56-,57-,58?,59-,60-,61-,62+,65-,66-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092654 (CHEMBL3586346) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-n1ccc2cc(F)ccc12 Show InChI InChI=1S/C20H21N5O6S/c1-25(9-10-2-3-12-11(8-10)17(28)24-20(21)23-12)15-6-5-14(32-15)18(29)22-13(19(30)31)4-7-16(26)27/h2-3,5-6,8,13H,4,7,9H2,1H3,(H,22,29)(H,26,27)(H,30,31)(H3,21,23,24,28)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092763 (CHEMBL3586322) Show SMILES COc1cc(cc2CN(Cc3ccc(cc3)S(C)(=O)=O)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C20H22Cl2N2/c21-18-7-4-8-19(20(18)22)24-11-9-23(10-12-24)14-16-13-17(16)15-5-2-1-3-6-15/h1-8,16-17H,9-14H2/t16-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092749 (CHEMBL3586324) Show SMILES COc1cc(cc2CN(Cc3cccc(c3)C#N)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C20H22Cl2N2/c21-19-7-6-17(13-20(19)22)24-10-8-23(9-11-24)14-16-12-18(16)15-4-2-1-3-5-15/h1-7,13,16,18H,8-12,14H2/t16-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM50092617 (CHEMBL3586309) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C24H22N2O2S/c1-27-22-12-18(21-16-29-23-7-3-2-6-20(21)23)11-19-15-26(9-10-28-24(19)22)14-17-5-4-8-25-13-17/h2-8,11-13,16H,9-10,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092655 (CHEMBL3586345) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-n1ccc2cc(ccc12)C#N Show InChI InChI=1S/C25H22N4O2/c1-30-24-13-22(29-8-6-20-11-18(14-26)4-5-23(20)29)12-21-17-28(9-10-31-25(21)24)16-19-3-2-7-27-15-19/h2-8,11-13,15H,9-10,16-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Rattus norvegicus)	BDBM50092617 (CHEMBL3586309) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C24H22N2O2S/c1-27-22-12-18(21-16-29-23-7-3-2-6-20(21)23)11-19-15-26(9-10-28-24(19)22)14-17-5-4-8-25-13-17/h2-8,11-13,16H,9-10,14-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from rat EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092758 (CHEMBL3586314) Show SMILES COc1ccc(CN2CCOc3c(C2)cc(cc3OC)-c2csc3ccccc23)cn1 Show InChI InChI=1S/C19H23N3/c1-2-4-16(5-3-1)19-14-17(19)15-21-10-12-22(13-11-21)18-6-8-20-9-7-18/h1-9,17,19H,10-15H2/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092619 (CHEMBL3586359) Show SMILES Clc1cc(cc2CN(Cc3cc[nH]c(=O)c3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C23H19ClN2O2S/c24-20-11-16(19-14-29-21-4-2-1-3-18(19)21)10-17-13-26(7-8-28-23(17)20)12-15-5-6-25-22(27)9-15/h1-6,9-11,14H,7-8,12-13H2,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092655 (CHEMBL3586345) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-n1ccc2cc(ccc12)C#N Show InChI InChI=1S/C25H22N4O2/c1-30-24-13-22(29-8-6-20-11-18(14-26)4-5-23(20)29)12-21-17-28(9-10-31-25(21)24)16-19-3-2-7-27-15-19/h2-8,11-13,15H,9-10,16-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092757 (CHEMBL3586315) Show SMILES COc1cc(cc2CN(Cc3ccc(=O)[nH]c3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C20H22ClFN2/c21-17-3-7-19(8-4-17)24-11-9-23(10-12-24)14-16-13-20(16)15-1-5-18(22)6-2-15/h1-8,16,20H,9-14H2/t16-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092759 (CHEMBL3586313) Show SMILES COc1cc(cc2CN(Cc3cccnc3OC)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C21H26N2O/c1-24-20-9-7-19(8-10-20)23-13-11-22(12-14-23)16-18-15-21(18)17-5-3-2-4-6-17/h2-10,18,21H,11-16H2,1H3/t18-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092761 (CHEMBL3586311) Show SMILES COc1cc(cc2CN(Cc3ccncc3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C21H25ClN2O/c1-25-21-8-7-18(22)14-20(21)24-11-9-23(10-12-24)15-17-13-19(17)16-5-3-2-4-6-16/h2-8,14,17,19H,9-13,15H2,1H3/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092639 (CHEMBL3586352) Show SMILES Cc1cc(cc2CN(Cc3cccnc3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C49H50FN5O7/c1-27(56)42-49(62)53-38(24-28-11-4-2-5-12-28)44(57)33-16-10-17-34(33)46(59)54-40(25-29-13-6-3-7-14-29)48(61)52-39-26-35-32-15-8-9-18-37(32)51-43(35)41(45(39)58)36(47(60)55-42)23-30-19-21-31(50)22-20-30/h2-9,11-15,18-22,27,33-34,36,38-42,51,56H,10,16-17,23-26H2,1H3,(H,52,61)(H,53,62)(H,54,59)(H,55,60)/t27?,33?,34-,36-,38+,39-,40+,41?,42+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092615 (CHEMBL3586361) Show SMILES C[C@@H]1COc2c(Cl)cc(cc2CN1Cc1cc[nH]c(=O)c1)-c1csc2ccccc12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Rattus norvegicus)	BDBM50092617 (CHEMBL3586309) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C24H22N2O2S/c1-27-22-12-18(21-16-29-23-7-3-2-6-20(21)23)11-19-15-26(9-10-28-24(19)22)14-17-5-4-8-25-13-17/h2-8,11-13,16H,9-10,14-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092745 (CHEMBL3586328) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-c1cccc2ccccc12 Show InChI InChI=1S/C21H24Cl2N2O/c1-26-21-19(22)12-17(13-20(21)23)25-9-7-24(8-10-25)14-16-11-18(16)15-5-3-2-4-6-15/h2-6,12-13,16,18H,7-11,14H2,1H3/t16-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092728 (CHEMBL3586337) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-n1ccc2ccccc12 Show InChI InChI=1S/C24H23N3O2/c1-28-23-14-21(27-10-8-19-6-2-3-7-22(19)27)13-20-17-26(11-12-29-24(20)23)16-18-5-4-9-25-15-18/h2-10,13-15H,11-12,16-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092724 (CHEMBL3586341) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-n1ccc2c(Cl)cccc12 Show InChI InChI=1S/C24H22ClN3O2/c1-29-23-13-19(28-9-7-20-21(25)5-2-6-22(20)28)12-18-16-27(10-11-30-24(18)23)15-17-4-3-8-26-14-17/h2-9,12-14H,10-11,15-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092730 (CHEMBL3586335) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-c1nsc2ccccc12 Show InChI InChI=1S/C23H21N3O2S/c1-27-20-12-17(22-19-6-2-3-7-21(19)29-25-22)11-18-15-26(9-10-28-23(18)20)14-16-5-4-8-24-13-16/h2-8,11-13H,9-10,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092757 (CHEMBL3586315) Show SMILES COc1cc(cc2CN(Cc3ccc(=O)[nH]c3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C20H22ClFN2/c21-17-3-7-19(8-4-17)24-11-9-23(10-12-24)14-16-13-20(16)15-1-5-18(22)6-2-15/h1-8,16,20H,9-14H2/t16-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092750 (CHEMBL3586321) Show SMILES COc1cc(cc2CN(Cc3ccc(cc3)C#N)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C19H23N3/c1-2-6-16(7-3-1)18-14-17(18)15-21-10-12-22(13-11-21)19-8-4-5-9-20-19/h1-9,17-18H,10-15H2/t17-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092751 (CHEMBL3586320) Show SMILES COC(=O)c1ccc(CN2CCOc3c(C2)cc(cc3OC)-c2csc3ccccc23)cc1 Show InChI InChI=1S/C20H23ClN2/c21-18-6-8-19(9-7-18)23-12-10-22(11-13-23)15-17-14-20(17)16-4-2-1-3-5-16/h1-9,17,20H,10-15H2/t17-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092617 (CHEMBL3586309) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C24H22N2O2S/c1-27-22-12-18(21-16-29-23-7-3-2-6-20(21)23)11-19-15-26(9-10-28-24(19)22)14-17-5-4-8-25-13-17/h2-8,11-13,16H,9-10,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092730 (CHEMBL3586335) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-c1nsc2ccccc12 Show InChI InChI=1S/C23H21N3O2S/c1-27-20-12-17(22-19-6-2-3-7-21(19)29-25-22)11-18-15-26(9-10-28-23(18)20)14-16-5-4-8-24-13-16/h2-8,11-13H,9-10,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092732 (CHEMBL3586333) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-c1cccc(Cl)c1 Show InChI InChI=1S/C22H21ClN2O2/c1-26-21-12-18(17-5-2-6-20(23)11-17)10-19-15-25(8-9-27-22(19)21)14-16-4-3-7-24-13-16/h2-7,10-13H,8-9,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092762 (CHEMBL3586310) Show SMILES COc1cc(cc2CN(Cc3ccccn3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C20H23ClN2/c21-18-7-4-8-19(14-18)23-11-9-22(10-12-23)15-17-13-20(17)16-5-2-1-3-6-16/h1-8,14,17,20H,9-13,15H2/t17-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092723 (CHEMBL3586342) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-n1ccc2cc(Cl)ccc12 Show InChI InChI=1S/C24H22ClN3O2/c1-29-23-13-21(28-8-6-18-11-20(25)4-5-22(18)28)12-19-16-27(9-10-30-24(19)23)15-17-3-2-7-26-14-17/h2-8,11-14H,9-10,15-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092722 (CHEMBL3586343) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-n1ccc2ccc(Cl)cc12 Show InChI InChI=1S/C24H22ClN3O2/c1-29-23-13-21(28-8-6-18-4-5-20(25)12-22(18)28)11-19-16-27(9-10-30-24(19)23)15-17-3-2-7-26-14-17/h2-8,11-14H,9-10,15-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assay				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092761 (CHEMBL3586311) Show SMILES COc1cc(cc2CN(Cc3ccncc3)CCOc12)-c1csc2ccccc12 Show InChI InChI=1S/C21H25ClN2O/c1-25-21-8-7-18(22)14-20(21)24-11-9-23(10-12-24)15-17-13-19(17)16-5-3-2-4-6-16/h2-8,14,17,19H,9-13,15H2,1H3/t17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50092725 (CHEMBL3586340) Show SMILES COc1cc(cc2CN(Cc3cccnc3)CCOc12)-n1cc(Cl)c2ccccc12 Show InChI InChI=1S/C24H22ClN3O2/c1-29-23-12-19(28-16-21(25)20-6-2-3-7-22(20)28)11-18-15-27(9-10-30-24(18)23)14-17-5-4-8-26-13-17/h2-8,11-13,16H,9-10,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP production				J Med Chem 58: 5256-73 (2015) Article DOI: 10.1021/acs.jmedchem.5b00567 BindingDB Entry DOI: 10.7270/Q2416ZSC
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 136 total )  |  Next  |  Last  >>

Jump to: