Found 6 hits Enz. Inhib. hit(s) with all data for entry = 50028875 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM3973
(N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide | ...)Show InChI InChI=1S/C9H9NO3/c11-6-10-4-3-7-5-8(12)1-2-9(7)13/h1-6,12-13H,(H,10,11)/b4-3+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of Epidermal growth factor receptor |
Bioorg Med Chem Lett 1: 165-168 (1991)
Article DOI: 10.1016/S0960-894X(01)80792-7 BindingDB Entry DOI: 10.7270/Q2WH2PWJ |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM4301
((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide...)Show InChI InChI=1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of Epidermal growth factor receptor |
Bioorg Med Chem Lett 1: 165-168 (1991)
Article DOI: 10.1016/S0960-894X(01)80792-7 BindingDB Entry DOI: 10.7270/Q2WH2PWJ |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50279860
(CHEMBL46946 | N-(3,4-dihydroxystyryl)formamide | N...)Show InChI InChI=1S/C9H9NO3/c11-6-10-4-3-7-1-2-8(12)9(13)5-7/h1-6,12-13H,(H,10,11)/b4-3+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of Epidermal growth factor receptor |
Bioorg Med Chem Lett 1: 165-168 (1991)
Article DOI: 10.1016/S0960-894X(01)80792-7 BindingDB Entry DOI: 10.7270/Q2WH2PWJ |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Lck
(Homo sapiens (Human)) | BDBM4301
((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide...)Show InChI InChI=1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of p56 lck tyrosine kinase |
Bioorg Med Chem Lett 1: 165-168 (1991)
Article DOI: 10.1016/S0960-894X(01)80792-7 BindingDB Entry DOI: 10.7270/Q2WH2PWJ |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50279861
((E)-2-Cyano-3-(2,5-dihydroxy-phenyl)-acrylamide | ...)Show InChI InChI=1S/C10H8N2O3/c11-5-7(10(12)15)3-6-4-8(13)1-2-9(6)14/h1-4,13-14H,(H2,12,15)/b7-3+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of Epidermal growth factor receptor |
Bioorg Med Chem Lett 1: 165-168 (1991)
Article DOI: 10.1016/S0960-894X(01)80792-7 BindingDB Entry DOI: 10.7270/Q2WH2PWJ |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Lck
(Homo sapiens (Human)) | BDBM50279861
((E)-2-Cyano-3-(2,5-dihydroxy-phenyl)-acrylamide | ...)Show InChI InChI=1S/C10H8N2O3/c11-5-7(10(12)15)3-6-4-8(13)1-2-9(6)14/h1-4,13-14H,(H2,12,15)/b7-3+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of p56 lck tyrosine kinase |
Bioorg Med Chem Lett 1: 165-168 (1991)
Article DOI: 10.1016/S0960-894X(01)80792-7 BindingDB Entry DOI: 10.7270/Q2WH2PWJ |
More data for this Ligand-Target Pair | |