Found 12 hits Enz. Inhib. hit(s) with all data for entry = 50029324 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50283416
(4-[7-(2,3-Dihydroxy-phenyl)-heptyloxy]-2-hydroxy-3...)Show InChI InChI=1S/C23H30O6/c1-2-9-17-20(14-13-18(22(17)26)23(27)28)29-15-7-5-3-4-6-10-16-11-8-12-19(24)21(16)25/h8,11-14,24-26H,2-7,9-10,15H2,1H3,(H,27,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells |
Bioorg Med Chem Lett 4: 339-344 (1994)
Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50283408
(4-[5-(2,3-Dihydroxy-phenyl)-pentyloxy]-2-hydroxy-3...)Show InChI InChI=1S/C21H26O6/c1-2-7-15-18(12-11-16(20(15)24)21(25)26)27-13-5-3-4-8-14-9-6-10-17(22)19(14)23/h6,9-12,22-24H,2-5,7-8,13H2,1H3,(H,25,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells |
Bioorg Med Chem Lett 4: 339-344 (1994)
Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM22372
(4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...)Show SMILES C[C@@H](Cc1ccc(O)c(O)c1)[C@H](C)Cc1ccc(O)c(O)c1 Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3/t11-,12+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells |
Bioorg Med Chem Lett 4: 339-344 (1994)
Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50283407
(4-[10-(2,3-Dihydroxy-phenyl)-decyloxy]-2-hydroxy-3...)Show SMILES CCCc1c(O)c(ccc1OCCCCCCCCCCc1cccc(O)c1O)C(O)=O Show InChI InChI=1S/C26H36O6/c1-2-12-20-23(17-16-21(25(20)29)26(30)31)32-18-10-8-6-4-3-5-7-9-13-19-14-11-15-22(27)24(19)28/h11,14-17,27-29H,2-10,12-13,18H2,1H3,(H,30,31) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells |
Bioorg Med Chem Lett 4: 339-344 (1994)
Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50283409
(4-[6-(2,3-Dihydroxy-phenyl)-hexyloxy]-2-hydroxy-3-...)Show InChI InChI=1S/C22H28O6/c1-2-8-16-19(13-12-17(21(16)25)22(26)27)28-14-6-4-3-5-9-15-10-7-11-18(23)20(15)24/h7,10-13,23-25H,2-6,8-9,14H2,1H3,(H,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells |
Bioorg Med Chem Lett 4: 339-344 (1994)
Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50283414
(4-[6-(2,3-Dihydroxy-phenyl)-hexyloxy]-3-propyl-ben...)Show InChI InChI=1S/C22H28O5/c1-2-8-17-15-18(22(25)26)12-13-20(17)27-14-6-4-3-5-9-16-10-7-11-19(23)21(16)24/h7,10-13,15,23-24H,2-6,8-9,14H2,1H3,(H,25,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells |
Bioorg Med Chem Lett 4: 339-344 (1994)
Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50283410
(4-[4-(2,3-Dihydroxy-phenyl)-butoxy]-2-hydroxy-3-pr...)Show InChI InChI=1S/C20H24O6/c1-2-6-14-17(11-10-15(19(14)23)20(24)25)26-12-4-3-7-13-8-5-9-16(21)18(13)22/h5,8-11,21-23H,2-4,6-7,12H2,1H3,(H,24,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells |
Bioorg Med Chem Lett 4: 339-344 (1994)
Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50283412
(4-[8-(2,3-Dihydroxy-phenyl)-octyloxy]-2-hydroxy-3-...)Show SMILES CCCc1c(O)c(ccc1OCCCCCCCCc1cccc(O)c1O)C(O)=O Show InChI InChI=1S/C24H32O6/c1-2-10-18-21(15-14-19(23(18)27)24(28)29)30-16-8-6-4-3-5-7-11-17-12-9-13-20(25)22(17)26/h9,12-15,25-27H,2-8,10-11,16H2,1H3,(H,28,29) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells |
Bioorg Med Chem Lett 4: 339-344 (1994)
Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50283413
(4-[3-(2,3-Dihydroxy-phenyl)-propoxy]-2-hydroxy-3-p...)Show InChI InChI=1S/C19H22O6/c1-2-5-13-16(10-9-14(18(13)22)19(23)24)25-11-4-7-12-6-3-8-15(20)17(12)21/h3,6,8-10,20-22H,2,4-5,7,11H2,1H3,(H,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells |
Bioorg Med Chem Lett 4: 339-344 (1994)
Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50283406
(4-[6-(2,3-Dihydroxy-phenyl)-hexyloxy]-benzoic acid...)Show InChI InChI=1S/C19H22O5/c20-17-8-5-7-14(18(17)21)6-3-1-2-4-13-24-16-11-9-15(10-12-16)19(22)23/h5,7-12,20-21H,1-4,6,13H2,(H,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells |
Bioorg Med Chem Lett 4: 339-344 (1994)
Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50283415
(4-[2-(2,3-Dihydroxy-phenyl)-ethoxy]-2-hydroxy-3-pr...)Show InChI InChI=1S/C18H20O6/c1-2-4-12-15(8-7-13(17(12)21)18(22)23)24-10-9-11-5-3-6-14(19)16(11)20/h3,5-8,19-21H,2,4,9-10H2,1H3,(H,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells |
Bioorg Med Chem Lett 4: 339-344 (1994)
Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50283411
(4-[6-(2,3-Dihydroxy-phenyl)-hexyloxy]-2-hydroxy-be...)Show InChI InChI=1S/C19H22O6/c20-16-8-5-7-13(18(16)22)6-3-1-2-4-11-25-14-9-10-15(19(23)24)17(21)12-14/h5,7-10,12,20-22H,1-4,6,11H2,(H,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells |
Bioorg Med Chem Lett 4: 339-344 (1994)
Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT |
More data for this
Ligand-Target Pair | |
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