Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Geranylgeranyl pyrophosphate synthase (Homo sapiens (Human)) | BDBM50151859 (CHEMBL3775876) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa Curated by ChEMBL | Assay Description Inhibition of recombinant GGDPS (unknown origin) assessed as radiolabeled GGPP formation preincubated for 10 mins followed by addition of 10 uM FPP s... | ACS Med Chem Lett 6: 1195-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00334 BindingDB Entry DOI: 10.7270/Q25B04DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Geranylgeranyl pyrophosphate synthase (Homo sapiens (Human)) | BDBM50151852 (CHEMBL3775694) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa Curated by ChEMBL | Assay Description Inhibition of recombinant GGDPS (unknown origin) assessed as radiolabeled GGPP formation preincubated for 10 mins followed by addition of 10 uM FPP s... | ACS Med Chem Lett 6: 1195-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00334 BindingDB Entry DOI: 10.7270/Q25B04DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Geranylgeranyl pyrophosphate synthase (Homo sapiens (Human)) | BDBM50151855 (CHEMBL3775345) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa Curated by ChEMBL | Assay Description Inhibition of recombinant GGDPS (unknown origin) assessed as radiolabeled GGPP formation preincubated for 10 mins followed by addition of 10 uM FPP s... | ACS Med Chem Lett 6: 1195-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00334 BindingDB Entry DOI: 10.7270/Q25B04DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Farnesyl pyrophosphate synthase (Homo sapiens (Human)) | BDBM50151855 (CHEMBL3775345) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa Curated by ChEMBL | Assay Description Inhibition of recombinant FDPS (unknown origin) assessed as radiolabeled FPP formation preincubated for 10 mins followed by addition of 10 uM GPP sub... | ACS Med Chem Lett 6: 1195-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00334 BindingDB Entry DOI: 10.7270/Q25B04DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Farnesyl pyrophosphate synthase (Homo sapiens (Human)) | BDBM50151852 (CHEMBL3775694) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa Curated by ChEMBL | Assay Description Inhibition of recombinant FDPS (unknown origin) assessed as radiolabeled FPP formation preincubated for 10 mins followed by addition of 10 uM GPP sub... | ACS Med Chem Lett 6: 1195-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00334 BindingDB Entry DOI: 10.7270/Q25B04DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Geranylgeranyl pyrophosphate synthase (Homo sapiens (Human)) | BDBM50013156 (CHEMBL3262351) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa Curated by ChEMBL | Assay Description Inhibition of recombinant GGDPS (unknown origin) assessed as radiolabeled GGPP formation preincubated for 10 mins followed by addition of 10 uM FPP s... | ACS Med Chem Lett 6: 1195-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00334 BindingDB Entry DOI: 10.7270/Q25B04DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Farnesyl pyrophosphate synthase (Homo sapiens (Human)) | BDBM50151859 (CHEMBL3775876) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Iowa Curated by ChEMBL | Assay Description Inhibition of recombinant FDPS (unknown origin) assessed as radiolabeled FPP formation preincubated for 10 mins followed by addition of 10 uM GPP sub... | ACS Med Chem Lett 6: 1195-8 (2015) Article DOI: 10.1021/acsmedchemlett.5b00334 BindingDB Entry DOI: 10.7270/Q25B04DN | |||||||||||
More data for this Ligand-Target Pair |