Compile Data Set for Download or QSAR

Found 176 hits Enz. Inhib. hit(s) with all data for entry = 50030495   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297088 ((S)-2-phenoxy-N-phenyl-N-(pyrrolidin-3-yl)benzamid...) Show SMILES O=C(N([C@H]1CCNC1)c1ccccc1)c1ccccc1Oc1ccccc1 |r| Show InChI InChI=1S/C23H22N2O2/c26-23(25(19-15-16-24-17-19)18-9-3-1-4-10-18)21-13-7-8-14-22(21)27-20-11-5-2-6-12-20/h1-14,19,24H,15-17H2/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus (rat))	BDBM50297077 ((S)-N-(cyclobutylmethyl)-N-(pyrrolidin-3-yl)-2-(tr...) Show SMILES FC(F)(F)c1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C17H21F3N2O/c18-17(19,20)15-7-2-1-6-14(15)16(23)22(11-12-4-3-5-12)13-8-9-21-10-13/h1-2,6-7,12-13,21H,3-5,8-11H2/t13-/m0/s1	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to rat NET expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297098 ((S)-N-cyclohexyl-2-(methylthio)-N-(pyrrolidin-3-yl...) Show SMILES CSc1ccccc1C(=O)N([C@H]1CCNC1)C1CCCCC1 |r| Show InChI InChI=1S/C18H26N2OS/c1-22-17-10-6-5-9-16(17)18(21)20(15-11-12-19-13-15)14-7-3-2-4-8-14/h5-6,9-10,14-15,19H,2-4,7-8,11-13H2,1H3/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262415 ((S)-N-(biphenyl-2-ylmethyl)-N-(pyrrolidin-3-yl)iso...) Show SMILES CC(C)C(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C21H26N2O/c1-16(2)21(24)23(19-12-13-22-14-19)15-18-10-6-7-11-20(18)17-8-4-3-5-9-17/h3-11,16,19,22H,12-15H2,1-2H3/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297078 ((S)-N-(cyclobutylmethyl)-2-(ethylthio)-N-(pyrrolid...) Show SMILES CCSc1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H26N2OS/c1-2-22-17-9-4-3-8-16(17)18(21)20(13-14-6-5-7-14)15-10-11-19-12-15/h3-4,8-9,14-15,19H,2,5-7,10-13H2,1H3/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297077 ((S)-N-(cyclobutylmethyl)-N-(pyrrolidin-3-yl)-2-(tr...) Show SMILES FC(F)(F)c1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C17H21F3N2O/c18-17(19,20)15-7-2-1-6-14(15)16(23)22(11-12-4-3-5-12)13-8-9-21-10-13/h1-2,6-7,12-13,21H,3-5,8-11H2/t13-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297081 ((S)-N-(cyclobutylmethyl)-2-phenoxy-N-(pyrrolidin-3...) Show SMILES O=C(N(CC1CCC1)[C@H]1CCNC1)c1ccccc1Oc1ccccc1 |r| Show InChI InChI=1S/C22H26N2O2/c25-22(24(16-17-7-6-8-17)18-13-14-23-15-18)20-11-4-5-12-21(20)26-19-9-2-1-3-10-19/h1-5,9-12,17-18,23H,6-8,13-16H2/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297091 ((S)-N-(cyclobutylmethyl)-2-(methylthio)-N-(pyrroli...) Show SMILES CSc1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C17H24N2OS/c1-21-16-8-3-2-7-15(16)17(20)19(12-13-5-4-6-13)14-9-10-18-11-14/h2-3,7-8,13-14,18H,4-6,9-12H2,1H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262678 ((S)-ethyl biphenyl-2-ylmethyl(pyrrolidin-3-yl)carb...) Show SMILES CCOC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C20H24N2O2/c1-2-24-20(23)22(18-12-13-21-14-18)15-17-10-6-7-11-19(17)16-8-4-3-5-9-16/h3-11,18,21H,2,12-15H2,1H3/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297087 ((S)-N-isobutyl-2-phenoxy-N-(pyrrolidin-3-yl)benzam...) Show SMILES CC(C)CN([C@H]1CCNC1)C(=O)c1ccccc1Oc1ccccc1 |r| Show InChI InChI=1S/C21H26N2O2/c1-16(2)15-23(17-12-13-22-14-17)21(24)19-10-6-7-11-20(19)25-18-8-4-3-5-9-18/h3-11,16-17,22H,12-15H2,1-2H3/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297085 ((S)-N-ethyl-2-phenoxy-N-(pyrrolidin-3-yl)benzamide...) Show SMILES CCN([C@H]1CCNC1)C(=O)c1ccccc1Oc1ccccc1 |r| Show InChI InChI=1S/C19H22N2O2/c1-2-21(15-12-13-20-14-15)19(22)17-10-6-7-11-18(17)23-16-8-4-3-5-9-16/h3-11,15,20H,2,12-14H2,1H3/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297096 ((S)-N-cyclopentyl-2-(methylthio)-N-(pyrrolidin-3-y...) Show SMILES CSc1ccccc1C(=O)N(C1CCCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C17H24N2OS/c1-21-16-9-5-4-8-15(16)17(20)19(13-6-2-3-7-13)14-10-11-18-12-14/h4-5,8-9,13-14,18H,2-3,6-7,10-12H2,1H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297079 ((S)-N-(cyclobutylmethyl)-2-isopropyl-N-(pyrrolidin...) Show SMILES CC(C)c1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C19H28N2O/c1-14(2)17-8-3-4-9-18(17)19(22)21(13-15-6-5-7-15)16-10-11-20-12-16/h3-4,8-9,14-16,20H,5-7,10-13H2,1-2H3/t16-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50236389 (CHEMBL273208 | N-methyl(6-methyl-4-(2-phenoxypheno...) Show SMILES CNCc1cnc(C)cc1Oc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C20H20N2O2/c1-15-12-20(16(13-21-2)14-22-15)24-19-11-7-6-10-18(19)23-17-8-4-3-5-9-17/h3-12,14,21H,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297086 ((S)-N-cyclobutyl-2-phenoxy-N-(pyrrolidin-3-yl)benz...) Show SMILES O=C(N(C1CCC1)[C@H]1CCNC1)c1ccccc1Oc1ccccc1 |r| Show InChI InChI=1S/C21H24N2O2/c24-21(23(16-7-6-8-16)17-13-14-22-15-17)19-11-4-5-12-20(19)25-18-9-2-1-3-10-18/h1-5,9-12,16-17,22H,6-8,13-15H2/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297082 ((S)-N-cyclobutyl-2-(methylthio)-N-(pyrrolidin-3-yl...) Show SMILES CSc1ccccc1C(=O)N(C1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C16H22N2OS/c1-20-15-8-3-2-7-14(15)16(19)18(12-5-4-6-12)13-9-10-17-11-13/h2-3,7-8,12-13,17H,4-6,9-11H2,1H3/t13-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297098 ((S)-N-cyclohexyl-2-(methylthio)-N-(pyrrolidin-3-yl...) Show SMILES CSc1ccccc1C(=O)N([C@H]1CCNC1)C1CCCCC1 |r| Show InChI InChI=1S/C18H26N2OS/c1-22-17-10-6-5-9-16(17)18(21)20(15-11-12-19-13-15)14-7-3-2-4-8-14/h5-6,9-10,14-15,19H,2-4,7-8,11-13H2,1H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297080 ((S)-N-(cyclobutylmethyl)-2-cyclopentyl-N-(pyrrolid...) Show SMILES O=C(N(CC1CCC1)[C@H]1CCNC1)c1ccccc1C1CCCC1 |r| Show InChI InChI=1S/C21H30N2O/c24-21(20-11-4-3-10-19(20)17-8-1-2-9-17)23(15-16-6-5-7-16)18-12-13-22-14-18/h3-4,10-11,16-18,22H,1-2,5-9,12-15H2/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297106 ((S)-N-(cyclopentylmethyl)-2-isopropyl-N-(pyrrolidi...) Show SMILES CC(C)c1ccccc1C(=O)N(CC1CCCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C20H30N2O/c1-15(2)18-9-5-6-10-19(18)20(23)22(17-11-12-21-13-17)14-16-7-3-4-8-16/h5-6,9-10,15-17,21H,3-4,7-8,11-14H2,1-2H3/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297097 ((S)-2-(methylthio)-N-phenyl-N-(pyrrolidin-3-yl)ben...) Show SMILES CSc1ccccc1C(=O)N([C@H]1CCNC1)c1ccccc1 |r| Show InChI InChI=1S/C18H20N2OS/c1-22-17-10-6-5-9-16(17)18(21)20(15-11-12-19-13-15)14-7-3-2-4-8-14/h2-10,15,19H,11-13H2,1H3/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297093 ((S)-2-chloro-N-(cyclobutylmethyl)-N-(pyrrolidin-3-...) Show SMILES Clc1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C16H21ClN2O/c17-15-7-2-1-6-14(15)16(20)19(11-12-4-3-5-12)13-8-9-18-10-13/h1-2,6-7,12-13,18H,3-5,8-11H2/t13-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297092 ((S)-N-(cyclobutylmethyl)-2-ethoxy-N-(pyrrolidin-3-...) Show SMILES CCOc1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H26N2O2/c1-2-22-17-9-4-3-8-16(17)18(21)20(13-14-6-5-7-14)15-10-11-19-12-15/h3-4,8-9,14-15,19H,2,5-7,10-13H2,1H3/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297102 ((S)-N-(cyclopentylmethyl)-N-(pyrrolidin-3-yl)-2-(t...) Show SMILES FC(F)(F)c1ccccc1C(=O)N(CC1CCCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H23F3N2O/c19-18(20,21)16-8-4-3-7-15(16)17(24)23(14-9-10-22-11-14)12-13-5-1-2-6-13/h3-4,7-8,13-14,22H,1-2,5-6,9-12H2/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297083 ((S)-N-phenyl-N-(pyrrolidin-3-yl)-2-(trifluoromethy...) Show SMILES FC(F)(F)c1ccccc1C(=O)N([C@H]1CCNC1)c1ccccc1 |r| Show InChI InChI=1S/C18H17F3N2O/c19-18(20,21)16-9-5-4-8-15(16)17(24)23(14-10-11-22-12-14)13-6-2-1-3-7-13/h1-9,14,22H,10-12H2/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297094 ((S)-N-(cyclobutylmethyl)-2-ethyl-N-(pyrrolidin-3-y...) Show SMILES CCc1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H26N2O/c1-2-15-8-3-4-9-17(15)18(21)20(13-14-6-5-7-14)16-10-11-19-12-16/h3-4,8-9,14,16,19H,2,5-7,10-13H2,1H3/t16-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297101 ((S)-N-(cyclopropylmethyl)-N-(pyrrolidin-3-yl)-2-(t...) Show SMILES FC(F)(F)c1ccccc1C(=O)N(CC1CC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C16H19F3N2O/c17-16(18,19)14-4-2-1-3-13(14)15(22)21(10-11-5-6-11)12-7-8-20-9-12/h1-4,11-12,20H,5-10H2/t12-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297104 ((S)-N-(cyclopropylmethyl)-2-isopropyl-N-(pyrrolidi...) Show SMILES CC(C)c1ccccc1C(=O)N(CC1CC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H26N2O/c1-13(2)16-5-3-4-6-17(16)18(21)20(12-14-7-8-14)15-9-10-19-11-15/h3-6,13-15,19H,7-12H2,1-2H3/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297084 ((S)-N-cyclopentyl-2-isopropyl-N-(pyrrolidin-3-yl)b...) Show SMILES CC(C)c1ccccc1C(=O)N(C1CCCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C19H28N2O/c1-14(2)17-9-5-6-10-18(17)19(22)21(15-7-3-4-8-15)16-11-12-20-13-16/h5-6,9-10,14-16,20H,3-4,7-8,11-13H2,1-2H3/t16-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297096 ((S)-N-cyclopentyl-2-(methylthio)-N-(pyrrolidin-3-y...) Show SMILES CSc1ccccc1C(=O)N(C1CCCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C17H24N2OS/c1-21-16-9-5-4-8-15(16)17(20)19(13-6-2-3-7-13)14-10-11-18-12-14/h4-5,8-9,13-14,18H,2-3,6-7,10-12H2,1H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297095 ((S)-2-(methylthio)-N-propyl-N-(pyrrolidin-3-yl)ben...) Show SMILES CCCN([C@H]1CCNC1)C(=O)c1ccccc1SC |r| Show InChI InChI=1S/C15H22N2OS/c1-3-10-17(12-8-9-16-11-12)15(18)13-6-4-5-7-14(13)19-2/h4-7,12,16H,3,8-11H2,1-2H3/t12-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297111 ((R)-N-(cyclobutylmethyl)-2-phenoxy-N-(pyrrolidin-3...) Show SMILES O=C(N(CC1CCC1)[C@@H]1CCNC1)c1ccccc1Oc1ccccc1 |r| Show InChI InChI=1S/C22H26N2O2/c25-22(24(16-17-7-6-8-17)18-13-14-23-15-18)20-11-4-5-12-21(20)26-19-9-2-1-3-10-19/h1-5,9-12,17-18,23H,6-8,13-16H2/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297093 ((S)-2-chloro-N-(cyclobutylmethyl)-N-(pyrrolidin-3-...) Show SMILES Clc1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C16H21ClN2O/c17-15-7-2-1-6-14(15)16(20)19(11-12-4-3-5-12)13-8-9-18-10-13/h1-2,6-7,12-13,18H,3-5,8-11H2/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297103 ((S)-N-cyclobutyl-2-isopropyl-N-(pyrrolidin-3-yl)be...) Show SMILES CC(C)c1ccccc1C(=O)N(C1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H26N2O/c1-13(2)16-8-3-4-9-17(16)18(21)20(14-6-5-7-14)15-10-11-19-12-15/h3-4,8-9,13-15,19H,5-7,10-12H2,1-2H3/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297100 ((S)-N-cyclobutyl-N-(pyrrolidin-3-yl)-2-(trifluorom...) Show SMILES FC(F)(F)c1ccccc1C(=O)N(C1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C16H19F3N2O/c17-16(18,19)14-7-2-1-6-13(14)15(22)21(11-4-3-5-11)12-8-9-20-10-12/h1-2,6-7,11-12,20H,3-5,8-10H2/t12-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297107 ((S)-N-methyl-2-phenoxy-N-(pyrrolidin-3-yl)benzamid...) Show SMILES CN([C@H]1CCNC1)C(=O)c1ccccc1Oc1ccccc1 |r| Show InChI InChI=1S/C18H20N2O2/c1-20(14-11-12-19-13-14)18(21)16-9-5-6-10-17(16)22-15-7-3-2-4-8-15/h2-10,14,19H,11-13H2,1H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297082 ((S)-N-cyclobutyl-2-(methylthio)-N-(pyrrolidin-3-yl...) Show SMILES CSc1ccccc1C(=O)N(C1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C16H22N2OS/c1-20-15-8-3-2-7-14(15)16(19)18(12-5-4-6-12)13-9-10-17-11-13/h2-3,7-8,12-13,17H,4-6,9-11H2,1H3/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297097 ((S)-2-(methylthio)-N-phenyl-N-(pyrrolidin-3-yl)ben...) Show SMILES CSc1ccccc1C(=O)N([C@H]1CCNC1)c1ccccc1 |r| Show InChI InChI=1S/C18H20N2OS/c1-22-17-10-6-5-9-16(17)18(21)20(15-11-12-19-13-15)14-7-3-2-4-8-14/h2-10,15,19H,11-13H2,1H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297088 ((S)-2-phenoxy-N-phenyl-N-(pyrrolidin-3-yl)benzamid...) Show SMILES O=C(N([C@H]1CCNC1)c1ccccc1)c1ccccc1Oc1ccccc1 |r| Show InChI InChI=1S/C23H22N2O2/c26-23(25(19-15-16-24-17-19)18-9-3-1-4-10-18)21-13-7-8-14-22(21)27-20-11-5-2-6-12-20/h1-14,19,24H,15-17H2/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297090 ((S)-N-(cyclobutylmethyl)-2-methyl-N-(pyrrolidin-3-...) Show SMILES Cc1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C17H24N2O/c1-13-5-2-3-8-16(13)17(20)19(12-14-6-4-7-14)15-9-10-18-11-15/h2-3,5,8,14-15,18H,4,6-7,9-12H2,1H3/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297105 ((S)-2-isopropyl-N-propyl-N-(pyrrolidin-3-yl)benzam...) Show SMILES CCCN([C@H]1CCNC1)C(=O)c1ccccc1C(C)C |r| Show InChI InChI=1S/C17H26N2O/c1-4-11-19(14-9-10-18-12-14)17(20)16-8-6-5-7-15(16)13(2)3/h5-8,13-14,18H,4,9-12H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297102 ((S)-N-(cyclopentylmethyl)-N-(pyrrolidin-3-yl)-2-(t...) Show SMILES FC(F)(F)c1ccccc1C(=O)N(CC1CCCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H23F3N2O/c19-18(20,21)16-8-4-3-7-15(16)17(24)23(14-9-10-22-11-14)12-13-5-1-2-6-13/h3-4,7-8,13-14,22H,1-2,5-6,9-12H2/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297083 ((S)-N-phenyl-N-(pyrrolidin-3-yl)-2-(trifluoromethy...) Show SMILES FC(F)(F)c1ccccc1C(=O)N([C@H]1CCNC1)c1ccccc1 |r| Show InChI InChI=1S/C18H17F3N2O/c19-18(20,21)16-9-5-4-8-15(16)17(24)23(14-10-11-22-12-14)13-6-2-1-3-7-13/h1-9,14,22H,10-12H2/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297090 ((S)-N-(cyclobutylmethyl)-2-methyl-N-(pyrrolidin-3-...) Show SMILES Cc1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C17H24N2O/c1-13-5-2-3-8-16(13)17(20)19(12-14-6-4-7-14)15-9-10-18-11-15/h2-3,5,8,14-15,18H,4,6-7,9-12H2,1H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297112 ((S)-N-(pyrrolidin-3-yl)-N-(2-(trifluoromethyl)benz...) Show SMILES FC(F)(F)c1ccccc1CN([C@H]1CCNC1)C(=O)C1CCC1 |r| Show InChI InChI=1S/C17H21F3N2O/c18-17(19,20)15-7-2-1-4-13(15)11-22(14-8-9-21-10-14)16(23)12-5-3-6-12/h1-2,4,7,12,14,21H,3,5-6,8-11H2/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297081 ((S)-N-(cyclobutylmethyl)-2-phenoxy-N-(pyrrolidin-3...) Show SMILES O=C(N(CC1CCC1)[C@H]1CCNC1)c1ccccc1Oc1ccccc1 |r| Show InChI InChI=1S/C22H26N2O2/c25-22(24(16-17-7-6-8-17)18-13-14-23-15-18)20-11-4-5-12-21(20)26-19-9-2-1-3-10-19/h1-5,9-12,17-18,23H,6-8,13-16H2/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	151	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297087 ((S)-N-isobutyl-2-phenoxy-N-(pyrrolidin-3-yl)benzam...) Show SMILES CC(C)CN([C@H]1CCNC1)C(=O)c1ccccc1Oc1ccccc1 |r| Show InChI InChI=1S/C21H26N2O2/c1-16(2)15-23(17-12-13-22-14-17)21(24)19-10-6-7-11-20(19)25-18-8-4-3-5-9-18/h3-11,16-17,22H,12-15H2,1-2H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297099 ((S)-N-isopropyl-N-(pyrrolidin-3-yl)-2-(trifluorome...) Show SMILES CC(C)N([C@H]1CCNC1)C(=O)c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C15H19F3N2O/c1-10(2)20(11-7-8-19-9-11)14(21)12-5-3-4-6-13(12)15(16,17)18/h3-6,10-11,19H,7-9H2,1-2H3/t11-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	172	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297091 ((S)-N-(cyclobutylmethyl)-2-(methylthio)-N-(pyrroli...) Show SMILES CSc1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C17H24N2OS/c1-21-16-8-3-2-7-15(16)17(20)19(12-13-5-4-6-13)14-9-10-18-11-14/h2-3,7-8,13-14,18H,4-6,9-12H2,1H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	179	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297112 ((S)-N-(pyrrolidin-3-yl)-N-(2-(trifluoromethyl)benz...) Show SMILES FC(F)(F)c1ccccc1CN([C@H]1CCNC1)C(=O)C1CCC1 |r| Show InChI InChI=1S/C17H21F3N2O/c18-17(19,20)15-7-2-1-4-13(15)11-22(14-8-9-21-10-14)16(23)12-5-3-6-12/h1-2,4,7,12,14,21H,3,5-6,8-11H2/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	187	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50297100 ((S)-N-cyclobutyl-N-(pyrrolidin-3-yl)-2-(trifluorom...) Show SMILES FC(F)(F)c1ccccc1C(=O)N(C1CCC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C16H19F3N2O/c17-16(18,19)14-7-2-1-6-13(14)15(22)21(11-4-3-5-11)12-8-9-20-10-12/h1-2,6-7,11-12,20H,3-5,8-10H2/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 4579-83 (2009) Article DOI: 10.1016/j.bmcl.2009.06.096 BindingDB Entry DOI: 10.7270/Q2NV9J96
					More data for this Ligand-Target Pair

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