Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 234 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing National Laboratory for Molecular Sciences Curated by ChEMBL | Assay Description Inhibition of Abl using DAIpYAAPFAKKK phosphopeptide as substrate by MALDI-MS analysis | Bioorg Med Chem Lett 21: 6964-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.127 BindingDB Entry DOI: 10.7270/Q289168N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50358832 (CHEMBL1923082) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing National Laboratory for Molecular Sciences Curated by ChEMBL | Assay Description Inhibition of Abl using DAIpYAAPFAKKK phosphopeptide as substrate by MALDI-MS analysis | Bioorg Med Chem Lett 21: 6964-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.127 BindingDB Entry DOI: 10.7270/Q289168N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50240407 (CHEMBL20926 | N-(4-methyl-3-(4-(pyridin-3-yl)pyrim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing National Laboratory for Molecular Sciences Curated by ChEMBL | Assay Description Inhibition of Abl using DAIpYAAPFAKKK phosphopeptide as substrate by MALDI-MS analysis | Bioorg Med Chem Lett 21: 6964-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.127 BindingDB Entry DOI: 10.7270/Q289168N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50358831 (CHEMBL1923084) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing National Laboratory for Molecular Sciences Curated by ChEMBL | Assay Description Inhibition of Abl using DAIpYAAPFAKKK phosphopeptide as substrate by MALDI-MS analysis | Bioorg Med Chem Lett 21: 6964-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.127 BindingDB Entry DOI: 10.7270/Q289168N | |||||||||||
More data for this Ligand-Target Pair |