Compile Data Set for Download or QSAR

Found 39 hits Enz. Inhib. hit(s) with all data for entry = 50038911   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50098551 ((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...) Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50261126 (CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCNS(=O)(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C24H29N3O3S/c1-30-24-10-5-4-9-23(24)27-17-15-26(16-18-27)14-6-13-25-31(28,29)22-12-11-20-7-2-3-8-21(20)19-22/h2-5,7-12,19,25H,6,13-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297895 (4-(2-methoxyphenyl)-N-(N-(naphthalen-1-ylmethyl)ca...) Show SMILES COc1ccccc1N1CCN(CC1)C(=O)NC(N)=NCc1cccc2ccccc12 |w:19.21| Show InChI InChI=1S/C24H27N5O2/c1-31-22-12-5-4-11-21(22)28-13-15-29(16-14-28)24(30)27-23(25)26-17-19-9-6-8-18-7-2-3-10-20(18)19/h2-12H,13-17H2,1H3,(H3,25,26,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297894 (2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...) Show SMILES O=S(=O)(c1ccccc1)C1(CCCN2CCc3ccccc3C2)CCC1 Show InChI InChI=1S/C22H27NO2S/c24-26(25,21-10-2-1-3-11-21)22(13-6-14-22)15-7-16-23-17-12-19-8-4-5-9-20(19)18-23/h1-5,8-11H,6-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50261126 (CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCNS(=O)(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C24H29N3O3S/c1-30-24-10-5-4-9-23(24)27-17-15-26(16-18-27)14-6-13-25-31(28,29)22-12-11-20-7-2-3-8-21(20)19-22/h2-5,7-12,19,25H,6,13-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297894 (2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...) Show SMILES O=S(=O)(c1ccccc1)C1(CCCN2CCc3ccccc3C2)CCC1 Show InChI InChI=1S/C22H27NO2S/c24-26(25,21-10-2-1-3-11-21)22(13-6-14-22)15-7-16-23-17-12-19-8-4-5-9-20(19)18-23/h1-5,8-11H,6-7,12-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297896 (CHEMBL561346 | N-[[(2-ethoxybenzyl)amino](imino)me...) Show SMILES CCOc1ccccc1CN=C(N)NC(=O)NC |w:10.10| Show InChI InChI=1S/C12H18N4O2/c1-3-18-10-7-5-4-6-9(10)8-15-11(13)16-12(17)14-2/h4-7H,3,8H2,1-2H3,(H4,13,14,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297894 (2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...) Show SMILES O=S(=O)(c1ccccc1)C1(CCCN2CCc3ccccc3C2)CCC1 Show InChI InChI=1S/C22H27NO2S/c24-26(25,21-10-2-1-3-11-21)22(13-6-14-22)15-7-16-23-17-12-19-8-4-5-9-20(19)18-23/h1-5,8-11H,6-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50261126 (CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCNS(=O)(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C24H29N3O3S/c1-30-24-10-5-4-9-23(24)27-17-15-26(16-18-27)14-6-13-25-31(28,29)22-12-11-20-7-2-3-8-21(20)19-22/h2-5,7-12,19,25H,6,13-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297903 (4-(2-methoxyphenyl)-N-(4-(4-methylphenylsulfonamid...) Show SMILES COc1ccccc1N1CCN(CC1)C(N)=NCCCCNS(=O)(=O)c1ccc(C)cc1 |w:16.18| Show InChI InChI=1S/C23H33N5O3S/c1-19-9-11-20(12-10-19)32(29,30)26-14-6-5-13-25-23(24)28-17-15-27(16-18-28)21-7-3-4-8-22(21)31-2/h3-4,7-12,26H,5-6,13-18H2,1-2H3,(H2,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297897 (4-methyl-N-(2-(3-methylphenylsulfonamido)ethyl)pip...) Show SMILES CC1CCN(CC1)C(N)=NCCNS(=O)(=O)c1cccc(C)c1 |w:9.10| Show InChI InChI=1S/C16H26N4O2S/c1-13-6-10-20(11-7-13)16(17)18-8-9-19-23(21,22)15-5-3-4-14(2)12-15/h3-5,12-13,19H,6-11H2,1-2H3,(H2,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297895 (4-(2-methoxyphenyl)-N-(N-(naphthalen-1-ylmethyl)ca...) Show SMILES COc1ccccc1N1CCN(CC1)C(=O)NC(N)=NCc1cccc2ccccc12 |w:19.21| Show InChI InChI=1S/C24H27N5O2/c1-31-22-12-5-4-11-21(22)28-13-15-29(16-14-28)24(30)27-23(25)26-17-19-9-6-8-18-7-2-3-10-20(18)19/h2-12H,13-17H2,1H3,(H3,25,26,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297902 (CHEMBL557740 | N-(4-(3-methylphenylsulfonamido)but...) Show SMILES Cc1cccc(c1)S(=O)(=O)NCCCCN=C(N)N1CCC(CC1)c1ccccc1 |w:15.15| Show InChI InChI=1S/C23H32N4O2S/c1-19-8-7-11-22(18-19)30(28,29)26-15-6-5-14-25-23(24)27-16-12-21(13-17-27)20-9-3-2-4-10-20/h2-4,7-11,18,21,26H,5-6,12-17H2,1H3,(H2,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297898 (CHEMBL558025 | N-(2-(3-methylphenylsulfonamido)eth...) Show SMILES Cc1cccc(c1)S(=O)(=O)NCCN=C(N)N1CCC(CC1)c1ccccc1 |w:13.13| Show InChI InChI=1S/C21H28N4O2S/c1-17-6-5-9-20(16-17)28(26,27)24-13-12-23-21(22)25-14-10-19(11-15-25)18-7-3-2-4-8-18/h2-9,16,19,24H,10-15H2,1H3,(H2,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297898 (CHEMBL558025 | N-(2-(3-methylphenylsulfonamido)eth...) Show SMILES Cc1cccc(c1)S(=O)(=O)NCCN=C(N)N1CCC(CC1)c1ccccc1 |w:13.13| Show InChI InChI=1S/C21H28N4O2S/c1-17-6-5-9-20(16-17)28(26,27)24-13-12-23-21(22)25-14-10-19(11-15-25)18-7-3-2-4-8-18/h2-9,16,19,24H,10-15H2,1H3,(H2,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	161	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297897 (4-methyl-N-(2-(3-methylphenylsulfonamido)ethyl)pip...) Show SMILES CC1CCN(CC1)C(N)=NCCNS(=O)(=O)c1cccc(C)c1 |w:9.10| Show InChI InChI=1S/C16H26N4O2S/c1-13-6-10-20(11-7-13)16(17)18-8-9-19-23(21,22)15-5-3-4-14(2)12-15/h3-5,12-13,19H,6-11H2,1-2H3,(H2,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297901 (4-(2-methoxyphenyl)-N-(3-(naphthalene-1-sulfonamid...) Show SMILES COc1ccccc1N1CCN(CC1)C(N)=NCCCNS(=O)(=O)c1cccc2ccccc12 |w:16.18| Show InChI InChI=1S/C25H31N5O3S/c1-33-23-12-5-4-11-22(23)29-16-18-30(19-17-29)25(26)27-14-7-15-28-34(31,32)24-13-6-9-20-8-2-3-10-21(20)24/h2-6,8-13,28H,7,14-19H2,1H3,(H2,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	195	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297904 (CHEMBL564509 | N-(4-(naphthalene-1-sulfonamido)but...) Show SMILES NC(=NCCCCNS(=O)(=O)c1cccc2ccccc12)N1CCc2ccccc2C1 |w:2.2| Show InChI InChI=1S/C24H28N4O2S/c25-24(28-17-14-19-8-1-2-10-21(19)18-28)26-15-5-6-16-27-31(29,30)23-13-7-11-20-9-3-4-12-22(20)23/h1-4,7-13,27H,5-6,14-18H2,(H2,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	195	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297904 (CHEMBL564509 | N-(4-(naphthalene-1-sulfonamido)but...) Show SMILES NC(=NCCCCNS(=O)(=O)c1cccc2ccccc12)N1CCc2ccccc2C1 |w:2.2| Show InChI InChI=1S/C24H28N4O2S/c25-24(28-17-14-19-8-1-2-10-21(19)18-28)26-15-5-6-16-27-31(29,30)23-13-7-11-20-9-3-4-12-22(20)23/h1-4,7-13,27H,5-6,14-18H2,(H2,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	198	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297900 (CHEMBL561750 | N-(3-(3-methylphenylsulfonamido)pro...) Show SMILES Cc1cccc(c1)S(=O)(=O)NCCCN=C(N)N1CCC(CC1)c1ccccc1 |w:14.14| Show InChI InChI=1S/C22H30N4O2S/c1-18-7-5-10-21(17-18)29(27,28)25-14-6-13-24-22(23)26-15-11-20(12-16-26)19-8-3-2-4-9-19/h2-5,7-10,17,20,25H,6,11-16H2,1H3,(H2,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	276	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297899 (4-(2-methoxyphenyl)-N-(2-(3-methylphenylsulfonamid...) Show SMILES COc1ccccc1N1CCN(CC1)C(N)=NCCNS(=O)(=O)c1cccc(C)c1 |w:16.18| Show InChI InChI=1S/C21H29N5O3S/c1-17-6-5-7-18(16-17)30(27,28)24-11-10-23-21(22)26-14-12-25(13-15-26)19-8-3-4-9-20(19)29-2/h3-9,16,24H,10-15H2,1-2H3,(H2,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	339	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297903 (4-(2-methoxyphenyl)-N-(4-(4-methylphenylsulfonamid...) Show SMILES COc1ccccc1N1CCN(CC1)C(N)=NCCCCNS(=O)(=O)c1ccc(C)cc1 |w:16.18| Show InChI InChI=1S/C23H33N5O3S/c1-19-9-11-20(12-10-19)32(29,30)26-14-6-5-13-25-23(24)28-17-15-27(16-18-28)21-7-3-4-8-22(21)31-2/h3-4,7-12,26H,5-6,13-18H2,1-2H3,(H2,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297896 (CHEMBL561346 | N-[[(2-ethoxybenzyl)amino](imino)me...) Show SMILES CCOc1ccccc1CN=C(N)NC(=O)NC |w:10.10| Show InChI InChI=1S/C12H18N4O2/c1-3-18-10-7-5-4-6-9(10)8-15-11(13)16-12(17)14-2/h4-7H,3,8H2,1-2H3,(H4,13,14,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297895 (4-(2-methoxyphenyl)-N-(N-(naphthalen-1-ylmethyl)ca...) Show SMILES COc1ccccc1N1CCN(CC1)C(=O)NC(N)=NCc1cccc2ccccc12 |w:19.21| Show InChI InChI=1S/C24H27N5O2/c1-31-22-12-5-4-11-21(22)28-13-15-29(16-14-28)24(30)27-23(25)26-17-19-9-6-8-18-7-2-3-10-20(18)19/h2-12H,13-17H2,1H3,(H3,25,26,27,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297902 (CHEMBL557740 | N-(4-(3-methylphenylsulfonamido)but...) Show SMILES Cc1cccc(c1)S(=O)(=O)NCCCCN=C(N)N1CCC(CC1)c1ccccc1 |w:15.15| Show InChI InChI=1S/C23H32N4O2S/c1-19-8-7-11-22(18-19)30(28,29)26-15-6-5-14-25-23(24)27-16-12-21(13-17-27)20-9-3-2-4-10-20/h2-4,7-11,18,21,26H,5-6,12-17H2,1H3,(H2,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297901 (4-(2-methoxyphenyl)-N-(3-(naphthalene-1-sulfonamid...) Show SMILES COc1ccccc1N1CCN(CC1)C(N)=NCCCNS(=O)(=O)c1cccc2ccccc12 |w:16.18| Show InChI InChI=1S/C25H31N5O3S/c1-33-23-12-5-4-11-22(23)29-16-18-30(19-17-29)25(26)27-14-7-15-28-34(31,32)24-13-6-9-20-8-2-3-10-21(20)24/h2-6,8-13,28H,7,14-19H2,1H3,(H2,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297897 (4-methyl-N-(2-(3-methylphenylsulfonamido)ethyl)pip...) Show SMILES CC1CCN(CC1)C(N)=NCCNS(=O)(=O)c1cccc(C)c1 |w:9.10| Show InChI InChI=1S/C16H26N4O2S/c1-13-6-10-20(11-7-13)16(17)18-8-9-19-23(21,22)15-5-3-4-14(2)12-15/h3-5,12-13,19H,6-11H2,1-2H3,(H2,17,18)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297899 (4-(2-methoxyphenyl)-N-(2-(3-methylphenylsulfonamid...) Show SMILES COc1ccccc1N1CCN(CC1)C(N)=NCCNS(=O)(=O)c1cccc(C)c1 |w:16.18| Show InChI InChI=1S/C21H29N5O3S/c1-17-6-5-7-18(16-17)30(27,28)24-11-10-23-21(22)26-14-12-25(13-15-26)19-8-3-4-9-20(19)29-2/h3-9,16,24H,10-15H2,1-2H3,(H2,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297900 (CHEMBL561750 | N-(3-(3-methylphenylsulfonamido)pro...) Show SMILES Cc1cccc(c1)S(=O)(=O)NCCCN=C(N)N1CCC(CC1)c1ccccc1 |w:14.14| Show InChI InChI=1S/C22H30N4O2S/c1-18-7-5-10-21(17-18)29(27,28)25-14-6-13-24-22(23)26-15-11-20(12-16-26)19-8-3-2-4-9-19/h2-5,7-10,17,20,25H,6,11-16H2,1H3,(H2,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297904 (CHEMBL564509 | N-(4-(naphthalene-1-sulfonamido)but...) Show SMILES NC(=NCCCCNS(=O)(=O)c1cccc2ccccc12)N1CCc2ccccc2C1 |w:2.2| Show InChI InChI=1S/C24H28N4O2S/c25-24(28-17-14-19-8-1-2-10-21(19)18-28)26-15-5-6-16-27-31(29,30)23-13-7-11-20-9-3-4-12-22(20)23/h1-4,7-13,27H,5-6,14-18H2,(H2,25,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297896 (CHEMBL561346 | N-[[(2-ethoxybenzyl)amino](imino)me...) Show SMILES CCOc1ccccc1CN=C(N)NC(=O)NC |w:10.10| Show InChI InChI=1S/C12H18N4O2/c1-3-18-10-7-5-4-6-9(10)8-15-11(13)16-12(17)14-2/h4-7H,3,8H2,1-2H3,(H4,13,14,15,16,17)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297898 (CHEMBL558025 | N-(2-(3-methylphenylsulfonamido)eth...) Show SMILES Cc1cccc(c1)S(=O)(=O)NCCN=C(N)N1CCC(CC1)c1ccccc1 |w:13.13| Show InChI InChI=1S/C21H28N4O2S/c1-17-6-5-9-20(16-17)28(26,27)24-13-12-23-21(22)25-14-10-19(11-15-25)18-7-3-2-4-8-18/h2-9,16,19,24H,10-15H2,1H3,(H2,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.56E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297901 (4-(2-methoxyphenyl)-N-(3-(naphthalene-1-sulfonamid...) Show SMILES COc1ccccc1N1CCN(CC1)C(N)=NCCCNS(=O)(=O)c1cccc2ccccc12 |w:16.18| Show InChI InChI=1S/C25H31N5O3S/c1-33-23-12-5-4-11-22(23)29-16-18-30(19-17-29)25(26)27-14-7-15-28-34(31,32)24-13-6-9-20-8-2-3-10-21(20)24/h2-6,8-13,28H,7,14-19H2,1H3,(H2,26,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	9.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098551 ((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...) Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50098551 ((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...) Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297903 (4-(2-methoxyphenyl)-N-(4-(4-methylphenylsulfonamid...) Show SMILES COc1ccccc1N1CCN(CC1)C(N)=NCCCCNS(=O)(=O)c1ccc(C)cc1 |w:16.18| Show InChI InChI=1S/C23H33N5O3S/c1-19-9-11-20(12-10-19)32(29,30)26-14-6-5-13-25-23(24)28-17-15-27(16-18-28)21-7-3-4-8-22(21)31-2/h3-4,7-12,26H,5-6,13-18H2,1-2H3,(H2,24,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297899 (4-(2-methoxyphenyl)-N-(2-(3-methylphenylsulfonamid...) Show SMILES COc1ccccc1N1CCN(CC1)C(N)=NCCNS(=O)(=O)c1cccc(C)c1 |w:16.18| Show InChI InChI=1S/C21H29N5O3S/c1-17-6-5-7-18(16-17)30(27,28)24-11-10-23-21(22)26-14-12-25(13-15-26)19-8-3-4-9-20(19)29-2/h3-9,16,24H,10-15H2,1-2H3,(H2,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297902 (CHEMBL557740 | N-(4-(3-methylphenylsulfonamido)but...) Show SMILES Cc1cccc(c1)S(=O)(=O)NCCCCN=C(N)N1CCC(CC1)c1ccccc1 |w:15.15| Show InChI InChI=1S/C23H32N4O2S/c1-19-8-7-11-22(18-19)30(28,29)26-15-6-5-14-25-23(24)27-16-12-21(13-17-27)20-9-3-2-4-10-20/h2-4,7-11,18,21,26H,5-6,12-17H2,1H3,(H2,24,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297900 (CHEMBL561750 | N-(3-(3-methylphenylsulfonamido)pro...) Show SMILES Cc1cccc(c1)S(=O)(=O)NCCCN=C(N)N1CCC(CC1)c1ccccc1 |w:14.14| Show InChI InChI=1S/C22H30N4O2S/c1-18-7-5-10-21(17-18)29(27,28)25-14-6-13-24-22(23)26-15-11-20(12-16-26)19-8-3-2-4-9-19/h2-5,7-10,17,20,25H,6,11-16H2,1H3,(H2,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair