Compile Data Set for Download or QSAR

Found 186 hits Enz. Inhib. hit(s) with all data for entry = 50002884   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464229 (CHEMBL4290409) Show SMILES O=S(=O)(N1CCN(CC1)c1cnc2ccccc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C19H18N4O4S/c24-28(25,14-5-6-17-18(11-14)27-13-26-17)23-9-7-22(8-10-23)19-12-20-15-3-1-2-4-16(15)21-19/h1-6,11-12H,7-10,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464230 (CHEMBL4291533) Show SMILES Clc1ccc(OC[C@H]2CCN2S(=O)(=O)c2ccc3OCOc3c2)cn1 |r| Show InChI InChI=1S/C16H15ClN2O5S/c17-16-4-1-12(8-18-16)22-9-11-5-6-19(11)25(20,21)13-2-3-14-15(7-13)24-10-23-14/h1-4,7-8,11H,5-6,9-10H2/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464231 (CHEMBL4283686) Show SMILES CCNC1=NC(C(S1)S(=O)(=O)c1ccc(cc1)C(C)(O)C(F)(F)F)C(F)(F)F |t:3| Show InChI InChI=1S/C15H16F6N2O3S2/c1-3-22-12-23-10(14(16,17)18)11(27-12)28(25,26)9-6-4-8(5-7-9)13(2,24)15(19,20)21/h4-7,10-11,24H,3H2,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464232 (CHEMBL4284303) Show SMILES Fc1ccc(NC2CN(C2)S(=O)(=O)c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C16H15FN2O4S/c17-11-1-3-12(4-2-11)18-13-8-19(9-13)24(20,21)14-5-6-15-16(7-14)23-10-22-15/h1-7,13,18H,8-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464233 (CHEMBL4293857) Show SMILES COc1cc(F)ccc1OC1CN(C1)S(=O)(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C17H16FNO6S/c1-22-16-6-11(18)2-4-15(16)25-12-8-19(9-12)26(20,21)13-3-5-14-17(7-13)24-10-23-14/h2-7,12H,8-10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464234 (CHEMBL4284872) Show SMILES COc1ccc(Cl)cc1OC1CN(C1)S(=O)(=O)c1ccc2[nH]c(=O)oc2c1 Show InChI InChI=1S/C17H15ClN2O6S/c1-24-14-5-2-10(18)6-16(14)25-11-8-20(9-11)27(22,23)12-3-4-13-15(7-12)26-17(21)19-13/h2-7,11H,8-9H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464235 (CHEMBL4287359) Show SMILES [H][C@]12CN(C[C@@]1([H])C(=O)N(C)CC2)S(=O)(=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C15H18N2O5S/c1-16-5-4-10-7-17(8-12(10)15(16)18)23(19,20)11-2-3-13-14(6-11)22-9-21-13/h2-3,6,10,12H,4-5,7-9H2,1H3/t10-,12+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464236 (CHEMBL4284350) Show SMILES O=S(=O)(N1CC(C1)c1nccc2ccccc12)c1ccc2OCOc2c1 Show InChI InChI=1S/C19H16N2O4S/c22-26(23,15-5-6-17-18(9-15)25-12-24-17)21-10-14(11-21)19-16-4-2-1-3-13(16)7-8-20-19/h1-9,14H,10-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464237 (CHEMBL4278843) Show SMILES COc1ccccc1O[C@H]1CCN(C1)S(=O)(=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C18H19NO6S/c1-22-15-4-2-3-5-17(15)25-13-8-9-19(11-13)26(20,21)14-6-7-16-18(10-14)24-12-23-16/h2-7,10,13H,8-9,11-12H2,1H3/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464238 (CHEMBL4287695) Show SMILES O=S(=O)(N1CCN(CC1)c1ccccc1)c1ccc2OCOc2c1 Show InChI InChI=1S/C17H18N2O4S/c20-24(21,15-6-7-16-17(12-15)23-13-22-16)19-10-8-18(9-11-19)14-4-2-1-3-5-14/h1-7,12H,8-11,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464239 (CHEMBL4287774) Show SMILES O=S(=O)(N1CCC(CC1)c1nc2ccccc2o1)c1ccc2OCOc2c1 Show InChI InChI=1S/C19H18N2O5S/c22-27(23,14-5-6-17-18(11-14)25-12-24-17)21-9-7-13(8-10-21)19-20-15-3-1-2-4-16(15)26-19/h1-6,11,13H,7-10,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464240 (CHEMBL4290216) Show SMILES O=S(=O)(N1CCO[C@@H](COc2ccccc2)C1)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C18H19NO6S/c20-26(21,16-6-7-17-18(10-16)25-13-24-17)19-8-9-22-15(11-19)12-23-14-4-2-1-3-5-14/h1-7,10,15H,8-9,11-13H2/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464241 (CHEMBL4290185) Show SMILES O=S(=O)(N1CCC(CC1)n1nnc2ccccc12)c1ccc2OCOc2c1 Show InChI InChI=1S/C18H18N4O4S/c23-27(24,14-5-6-17-18(11-14)26-12-25-17)21-9-7-13(8-10-21)22-16-4-2-1-3-15(16)19-20-22/h1-6,11,13H,7-10,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464242 (CHEMBL4285933) Show SMILES COCCCN1CCN(CC1)S(=O)(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C15H22N2O5S/c1-20-10-2-5-16-6-8-17(9-7-16)23(18,19)13-3-4-14-15(11-13)22-12-21-14/h3-4,11H,2,5-10,12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464243 (CHEMBL4293822) Show SMILES O=S(=O)(N1CCN(CCN2CCCCC2)CC1)c1ccc2OCOc2c1 Show InChI InChI=1S/C18H27N3O4S/c22-26(23,16-4-5-17-18(14-16)25-15-24-17)21-12-10-20(11-13-21)9-8-19-6-2-1-3-7-19/h4-5,14H,1-3,6-13,15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464244 (CHEMBL4279071) Show SMILES COc1cccc(COC2CN(C2)S(=O)(=O)c2ccc3OCOc3c2)c1 Show InChI InChI=1S/C18H19NO6S/c1-22-14-4-2-3-13(7-14)11-23-15-9-19(10-15)26(20,21)16-5-6-17-18(8-16)25-12-24-17/h2-8,15H,9-12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464245 (CHEMBL4283192) Show SMILES O=S(=O)(N1CC(C1)OCc1ccccn1)c1ccc2OCOc2c1 Show InChI InChI=1S/C16H16N2O5S/c19-24(20,14-4-5-15-16(7-14)23-11-22-15)18-8-13(9-18)21-10-12-3-1-2-6-17-12/h1-7,13H,8-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464246 (CHEMBL4280193) Show SMILES COc1ccc(OC2CN(C2)S(=O)(=O)c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C17H17NO6S/c1-21-12-2-4-13(5-3-12)24-14-9-18(10-14)25(19,20)15-6-7-16-17(8-15)23-11-22-16/h2-8,14H,9-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464247 (CHEMBL4294144) Show SMILES CC[C@@H]1N(CCn2cccc12)S(=O)(=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C16H18N2O4S/c1-2-13-14-4-3-7-17(14)8-9-18(13)23(19,20)12-5-6-15-16(10-12)22-11-21-15/h3-7,10,13H,2,8-9,11H2,1H3/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464248 (CHEMBL4290217) Show SMILES Fc1ccccc1CN1CCN(CC1)S(=O)(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C18H19FN2O4S/c19-16-4-2-1-3-14(16)12-20-7-9-21(10-8-20)26(22,23)15-5-6-17-18(11-15)25-13-24-17/h1-6,11H,7-10,12-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464249 (CHEMBL4286392) Show SMILES O=S(=O)(N1CCN(C[C@@H]2CCCO2)CC1)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C16H22N2O5S/c19-24(20,14-3-4-15-16(10-14)23-12-22-15)18-7-5-17(6-8-18)11-13-2-1-9-21-13/h3-4,10,13H,1-2,5-9,11-12H2/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464250 (CHEMBL4278475) Show SMILES COc1cccc(OC2CN(C2)S(=O)(=O)c2ccc3OCOc3c2)c1 Show InChI InChI=1S/C17H17NO6S/c1-21-12-3-2-4-13(7-12)24-14-9-18(10-14)25(19,20)15-5-6-16-17(8-15)23-11-22-16/h2-8,14H,9-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464251 (CHEMBL4281948) Show SMILES O=S(=O)(N1CCN(Cc2ccccn2)CC1)c1ccc2OCOc2c1 Show InChI InChI=1S/C17H19N3O4S/c21-25(22,15-4-5-16-17(11-15)24-13-23-16)20-9-7-19(8-10-20)12-14-3-1-2-6-18-14/h1-6,11H,7-10,12-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464252 (CHEMBL4293193) Show SMILES O=S(=O)(N1CC(C1)Oc1ccccc1)c1ccc2OCOc2c1 Show InChI InChI=1S/C16H15NO5S/c18-23(19,14-6-7-15-16(8-14)21-11-20-15)17-9-13(10-17)22-12-4-2-1-3-5-12/h1-8,13H,9-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464253 (CHEMBL4290872) Show SMILES Fc1ccc(CN2CCN(CC2)S(=O)(=O)c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C18H19FN2O4S/c19-15-3-1-14(2-4-15)12-20-7-9-21(10-8-20)26(22,23)16-5-6-17-18(11-16)25-13-24-17/h1-6,11H,7-10,12-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464231 (CHEMBL4283686) Show SMILES CCNC1=NC(C(S1)S(=O)(=O)c1ccc(cc1)C(C)(O)C(F)(F)F)C(F)(F)F |t:3| Show InChI InChI=1S/C15H16F6N2O3S2/c1-3-22-12-23-10(14(16,17)18)11(27-12)28(25,26)9-6-4-8(5-7-9)13(2,24)15(19,20)21/h4-7,10-11,24H,3H2,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464231 (CHEMBL4283686) Show SMILES CCNC1=NC(C(S1)S(=O)(=O)c1ccc(cc1)C(C)(O)C(F)(F)F)C(F)(F)F |t:3| Show InChI InChI=1S/C15H16F6N2O3S2/c1-3-22-12-23-10(14(16,17)18)11(27-12)28(25,26)9-6-4-8(5-7-9)13(2,24)15(19,20)21/h4-7,10-11,24H,3H2,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464254 (CHEMBL4276816) Show SMILES CC(O)(c1ccc(cc1)S(=O)(=O)C1SC(=NC1C(F)(F)F)N1CCCCC1)C(F)(F)F |c:15| Show InChI InChI=1S/C18H20F6N2O3S2/c1-16(27,18(22,23)24)11-5-7-12(8-6-11)31(28,29)14-13(17(19,20)21)25-15(30-14)26-9-3-2-4-10-26/h5-8,13-14,27H,2-4,9-10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464254 (CHEMBL4276816) Show SMILES CC(O)(c1ccc(cc1)S(=O)(=O)C1SC(=NC1C(F)(F)F)N1CCCCC1)C(F)(F)F |c:15| Show InChI InChI=1S/C18H20F6N2O3S2/c1-16(27,18(22,23)24)11-5-7-12(8-6-11)31(28,29)14-13(17(19,20)21)25-15(30-14)26-9-3-2-4-10-26/h5-8,13-14,27H,2-4,9-10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464254 (CHEMBL4276816) Show SMILES CC(O)(c1ccc(cc1)S(=O)(=O)C1SC(=NC1C(F)(F)F)N1CCCCC1)C(F)(F)F |c:15| Show InChI InChI=1S/C18H20F6N2O3S2/c1-16(27,18(22,23)24)11-5-7-12(8-6-11)31(28,29)14-13(17(19,20)21)25-15(30-14)26-9-3-2-4-10-26/h5-8,13-14,27H,2-4,9-10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-1/beta (Homo sapiens (Human))	BDBM50464255 (CHEMBL4083687) Show SMILES [H][C@@]12CN(C[C@]1([H])c1ccccc1N(C)C2=O)S(=O)(=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C19H18N2O5S/c1-20-16-5-3-2-4-13(16)14-9-21(10-15(14)19(20)22)27(23,24)12-6-7-17-18(8-12)26-11-25-17/h2-8,14-15H,9-11H2,1H3/t14-,15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha1beta assessed as increase in glycine-induced chloride ion flux by FLIPR assay				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-1/beta (Homo sapiens (Human))	BDBM50464234 (CHEMBL4284872) Show SMILES COc1ccc(Cl)cc1OC1CN(C1)S(=O)(=O)c1ccc2[nH]c(=O)oc2c1 Show InChI InChI=1S/C17H15ClN2O6S/c1-24-14-5-2-10(18)6-16(14)25-11-8-20(9-11)27(22,23)12-3-4-13-15(7-12)26-17(21)19-13/h2-7,11H,8-9H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha1beta assessed as increase in glycine-induced chloride ion flux by FLIPR assay				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50464234 (CHEMBL4284872) Show SMILES COc1ccc(Cl)cc1OC1CN(C1)S(=O)(=O)c1ccc2[nH]c(=O)oc2c1 Show InChI InChI=1S/C17H15ClN2O6S/c1-24-14-5-2-10(18)6-16(14)25-11-8-20(9-11)27(22,23)12-3-4-13-15(7-12)26-17(21)19-13/h2-7,11H,8-9H2,1H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Binding affinity to human GlyRalpha3cryst by SPR method				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50464234 (CHEMBL4284872) Show SMILES COc1ccc(Cl)cc1OC1CN(C1)S(=O)(=O)c1ccc2[nH]c(=O)oc2c1 Show InChI InChI=1S/C17H15ClN2O6S/c1-24-14-5-2-10(18)6-16(14)25-11-8-20(9-11)27(22,23)12-3-4-13-15(7-12)26-17(21)19-13/h2-7,11H,8-9H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Potentiation of human GABAA alpha1beta2gamma2 receptor				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464231 (CHEMBL4283686) Show SMILES CCNC1=NC(C(S1)S(=O)(=O)c1ccc(cc1)C(C)(O)C(F)(F)F)C(F)(F)F |t:3| Show InChI InChI=1S/C15H16F6N2O3S2/c1-3-22-12-23-10(14(16,17)18)11(27-12)28(25,26)9-6-4-8(5-7-9)13(2,24)15(19,20)21/h4-7,10-11,24H,3H2,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464254 (CHEMBL4276816) Show SMILES CC(O)(c1ccc(cc1)S(=O)(=O)C1SC(=NC1C(F)(F)F)N1CCCCC1)C(F)(F)F |c:15| Show InChI InChI=1S/C18H20F6N2O3S2/c1-16(27,18(22,23)24)11-5-7-12(8-6-11)31(28,29)14-13(17(19,20)21)25-15(30-14)26-9-3-2-4-10-26/h5-8,13-14,27H,2-4,9-10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464254 (CHEMBL4276816) Show SMILES CC(O)(c1ccc(cc1)S(=O)(=O)C1SC(=NC1C(F)(F)F)N1CCCCC1)C(F)(F)F |c:15| Show InChI InChI=1S/C18H20F6N2O3S2/c1-16(27,18(22,23)24)11-5-7-12(8-6-11)31(28,29)14-13(17(19,20)21)25-15(30-14)26-9-3-2-4-10-26/h5-8,13-14,27H,2-4,9-10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464256 (CHEMBL4294200) Show SMILES Fc1ccccc1[C@H]1CCN(C1)S(=O)(=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C17H16FNO4S/c18-15-4-2-1-3-14(15)12-7-8-19(10-12)24(20,21)13-5-6-16-17(9-13)23-11-22-16/h1-6,9,12H,7-8,10-11H2/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464257 (CHEMBL4290271) Show SMILES COc1ccccc1OC1CN(C1)S(=O)(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C17H17NO6S/c1-21-14-4-2-3-5-16(14)24-12-9-18(10-12)25(19,20)13-6-7-15-17(8-13)23-11-22-15/h2-8,12H,9-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464258 (CHEMBL4285964) Show SMILES COc1ccc(F)cc1OC1CN(C1)S(=O)(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C17H16FNO6S/c1-22-14-4-2-11(18)6-17(14)25-12-8-19(9-12)26(20,21)13-3-5-15-16(7-13)24-10-23-15/h2-7,12H,8-10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464259 (CHEMBL4290451) Show SMILES COc1cccc(F)c1OC1CN(C1)S(=O)(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C17H16FNO6S/c1-22-15-4-2-3-13(18)17(15)25-11-8-19(9-11)26(20,21)12-5-6-14-16(7-12)24-10-23-14/h2-7,11H,8-10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464260 (CHEMBL4282176) Show SMILES COc1ccc(C)cc1OC1CN(C1)S(=O)(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C18H19NO6S/c1-12-3-5-15(22-2)18(7-12)25-13-9-19(10-13)26(20,21)14-4-6-16-17(8-14)24-11-23-16/h3-8,13H,9-11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464261 (CHEMBL4292781) Show SMILES COc1ccc(Cl)cc1O[C@@H]1CN([C@@H]1C)S(=O)(=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C18H18ClNO6S/c1-11-18(26-17-7-12(19)3-5-14(17)23-2)9-20(11)27(21,22)13-4-6-15-16(8-13)25-10-24-15/h3-8,11,18H,9-10H2,1-2H3/t11-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464262 (CHEMBL4280233) Show SMILES COc1ccc(Cl)cc1O[C@H]1CN([C@@H]1C)S(=O)(=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C18H18ClNO6S/c1-11-18(26-17-7-12(19)3-5-14(17)23-2)9-20(11)27(21,22)13-4-6-15-16(8-13)25-10-24-15/h3-8,11,18H,9-10H2,1-2H3/t11-,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464263 (CHEMBL4277386) Show SMILES COc1ccc(Cl)cc1OC1CN(C1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C17H16ClN3O4S/c1-24-16-5-3-12(18)6-17(16)25-13-9-21(10-13)26(22,23)14-4-2-11-8-19-20-15(11)7-14/h2-8,13H,9-10H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464264 (CHEMBL4295252) Show SMILES COc1ccc(Cl)cc1OC1CN(C1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C17H16ClN3O4S/c1-24-16-5-2-12(18)7-17(16)25-13-9-21(10-13)26(22,23)14-3-4-15-11(6-14)8-19-20-15/h2-8,13H,9-10H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464265 (CHEMBL4292523) Show SMILES COc1ccc(Cl)cc1OC1CN(C1)S(=O)(=O)c1ccc2n(C)ncc2c1 Show InChI InChI=1S/C18H18ClN3O4S/c1-21-16-5-4-15(7-12(16)9-20-21)27(23,24)22-10-14(11-22)26-18-8-13(19)3-6-17(18)25-2/h3-9,14H,10-11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464266 (CHEMBL4282966) Show SMILES N[C@H]1CN(C[C@H]1c1ccccc1)S(=O)(=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C17H18N2O4S/c18-15-10-19(9-14(15)12-4-2-1-3-5-12)24(20,21)13-6-7-16-17(8-13)23-11-22-16/h1-8,14-15H,9-11,18H2/t14-,15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464267 (CHEMBL4288687) Show SMILES O=S(=O)(N1CC[C@](C1)(C#N)c1ccccc1)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C18H16N2O4S/c19-11-18(14-4-2-1-3-5-14)8-9-20(12-18)25(21,22)15-6-7-16-17(10-15)24-13-23-16/h1-7,10H,8-9,12-13H2/t18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464268 (CHEMBL4279655) Show SMILES O=C1Cc2ccccc2N1C1CCN(CC1)S(=O)(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C20H20N2O5S/c23-20-11-14-3-1-2-4-17(14)22(20)15-7-9-21(10-8-15)28(24,25)16-5-6-18-19(12-16)27-13-26-18/h1-6,12,15H,7-11,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
					More data for this Ligand-Target Pair

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