Compile Data Set for Download or QSAR

Found 101 hits Enz. Inhib. hit(s) with all data for entry = 50015387   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311206 ((S)-1-(2-(difluoromethyl)-4-(2-methylpyridin-4-yl)...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)F)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C20H26F2N2O/c1-13(2)11-20(4,23)12-25-18-6-5-15(10-17(18)19(21)22)16-7-8-24-14(3)9-16/h5-10,13,19H,11-12,23H2,1-4H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311193 ((S)-1-(2-(difluoromethyl)-4-(2-(difluoromethyl)pyr...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)F)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C20H24F4N2O/c1-12(2)10-20(3,25)11-27-17-5-4-13(8-15(17)18(21)22)14-6-7-26-16(9-14)19(23)24/h4-9,12,18-19H,10-11,25H2,1-3H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311199 ((S)-2,4-dimethyl-1-(4-(pyridin-4-yl)-2-(trifluorom...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccncc1 |r| Show InChI InChI=1S/C19H23F3N2O/c1-13(2)11-18(3,23)12-25-17-5-4-15(10-16(17)19(20,21)22)14-6-8-24-9-7-14/h4-10,13H,11-12,23H2,1-3H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311191 ((S)-1-(4-(2-(difluoromethyl)pyridin-4-yl)-2-(trifl...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C20H23F5N2O/c1-12(2)10-19(3,26)11-28-17-5-4-13(8-15(17)20(23,24)25)14-6-7-27-16(9-14)18(21)22/h4-9,12,18H,10-11,26H2,1-3H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311192 ((S)-2-((2-amino-2,4-dimethylpentyl)oxy)-5-(2-(difl...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C#N)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C20H23F2N3O/c1-13(2)10-20(3,24)12-26-18-5-4-14(8-16(18)11-23)15-6-7-25-17(9-15)19(21)22/h4-9,13,19H,10,12,24H2,1-3H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311270 ((S)-1-(2-cyclopropyl-4-(2-(difluoromethyl)pyridin-...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C1CC1)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C22H28F2N2O/c1-14(2)12-22(3,25)13-27-20-7-6-16(10-18(20)15-4-5-15)17-8-9-26-19(11-17)21(23)24/h6-11,14-15,21H,4-5,12-13,25H2,1-3H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311166 ( (S)-2-((2-amino-4-methylpentyl)oxy)-5-(2-methylpy...) Show SMILES CC(C)C[C@H](N)COc1ccc(cc1C#N)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C19H23N3O/c1-13(2)8-18(21)12-23-19-5-4-15(10-17(19)11-20)16-6-7-22-14(3)9-16/h4-7,9-10,13,18H,8,12,21H2,1-3H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311206 ((S)-1-(2-(difluoromethyl)-4-(2-methylpyridin-4-yl)...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)F)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C20H26F2N2O/c1-13(2)11-20(4,23)12-25-18-6-5-15(10-17(18)19(21)22)16-7-8-24-14(3)9-16/h5-10,13,19H,11-12,23H2,1-4H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311193 ((S)-1-(2-(difluoromethyl)-4-(2-(difluoromethyl)pyr...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)F)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C20H24F4N2O/c1-12(2)10-20(3,25)11-27-17-5-4-13(8-15(17)18(21)22)14-6-7-26-16(9-14)19(23)24/h4-9,12,18-19H,10-11,25H2,1-3H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311201 ((S)-2,4-dimethyl-1-(4-(2-methylpyridin-4-yl)-2-(tr...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C20H25F3N2O/c1-13(2)11-19(4,24)12-26-18-6-5-15(10-17(18)20(21,22)23)16-7-8-25-14(3)9-16/h5-10,13H,11-12,24H2,1-4H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311304 (((S)-1-((6-chloro-2′-(difluoromethyl)-[2,4&#...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(nc1Cl)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C23H30ClF2N3O3/c1-14(2)12-23(6,29-21(30)32-22(3,4)5)13-31-18-8-7-16(28-19(18)24)15-9-10-27-17(11-15)20(25)26/h7-11,14,20H,12-13H2,1-6H3,(H,29,30)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311337 ((S)-1-((5-(difluoromethyl)-2′-methyl-[3,4...) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C(F)F)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C19H25F2N3O/c1-12(2)9-19(4,22)11-25-18-16(17(20)21)8-15(10-24-18)14-5-6-23-13(3)7-14/h5-8,10,12,17H,9,11,22H2,1-4H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311267 ((S)-1-((2′,6-bis(difluoromethyl)-[2,4′...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(nc1C(F)F)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C19H23F4N3O/c1-11(2)9-19(3,24)10-27-15-5-4-13(26-16(15)18(22)23)12-6-7-25-14(8-12)17(20)21/h4-8,11,17-18H,9-10,24H2,1-3H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311267 ((S)-1-((2′,6-bis(difluoromethyl)-[2,4′...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(nc1C(F)F)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C19H23F4N3O/c1-11(2)9-19(3,24)10-27-15-5-4-13(26-16(15)18(22)23)12-6-7-25-14(8-12)17(20)21/h4-8,11,17-18H,9-10,24H2,1-3H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311200 ((S)-1-(4-(2-fluoropyridin-4-yl)-2-(trifluoromethyl...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc(F)c1 |r| Show InChI InChI=1S/C19H22F4N2O/c1-12(2)10-18(3,24)11-26-16-5-4-13(8-15(16)19(21,22)23)14-6-7-25-17(20)9-14/h4-9,12H,10-11,24H2,1-3H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311205 ((S)-1-(2-cyclopropyl-4-(2-methylpyridin-4-yl)pheno...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C1CC1)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C22H30N2O/c1-15(2)13-22(4,23)14-25-21-8-7-18(12-20(21)17-5-6-17)19-9-10-24-16(3)11-19/h7-12,15,17H,5-6,13-14,23H2,1-4H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50586144 (CHEMBL5074638) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C)-c1ccnc(c1)C(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311263 ((S)-1-((6-(difluoromethyl)-2′-methyl-[2,4...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(nc1C(F)F)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C19H25F2N3O/c1-12(2)10-19(4,22)11-25-16-6-5-15(24-17(16)18(20)21)14-7-8-23-13(3)9-14/h5-9,12,18H,10-11,22H2,1-4H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311336 ((S)-1-((2′-chloro-5-(difluoromethyl)-[3,4...) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C(F)F)-c1ccnc(Cl)c1 |r| Show InChI InChI=1S/C18H22ClF2N3O/c1-11(2)8-18(3,22)10-25-17-14(16(20)21)6-13(9-24-17)12-4-5-23-15(19)7-12/h4-7,9,11,16H,8,10,22H2,1-3H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50586145 (CHEMBL5078653) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C#N)-c1ccnc(c1)C(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311301 ((S)-1-((2′-chloro-6-(difluoromethyl)-[2,4...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(nc1C(F)F)-c1ccnc(Cl)c1 |r| Show InChI InChI=1S/C18H22ClF2N3O/c1-11(2)9-18(3,22)10-25-14-5-4-13(24-16(14)17(20)21)12-6-7-23-15(19)8-12/h4-8,11,17H,9-10,22H2,1-3H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311204 ((S)-2-((2-amino-2,4-dimethylpentyl)oxy)-5-(2-methy...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C#N)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C20H25N3O/c1-14(2)11-20(4,22)13-24-19-6-5-16(10-18(19)12-21)17-7-8-23-15(3)9-17/h5-10,14H,11,13,22H2,1-4H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311192 ((S)-2-((2-amino-2,4-dimethylpentyl)oxy)-5-(2-(difl...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C#N)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C20H23F2N3O/c1-13(2)10-20(3,24)12-26-18-5-4-14(8-16(18)11-23)15-6-7-25-17(9-15)19(21)22/h4-9,13,19H,10,12,24H2,1-3H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50586142 (CHEMBL5088767) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C)-c1ccnc(Cl)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311191 ((S)-1-(4-(2-(difluoromethyl)pyridin-4-yl)-2-(trifl...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C20H23F5N2O/c1-12(2)10-19(3,26)11-28-17-5-4-13(8-15(17)20(23,24)25)14-6-7-27-16(9-14)18(21)22/h4-9,12,18H,10-11,26H2,1-3H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311270 ((S)-1-(2-cyclopropyl-4-(2-(difluoromethyl)pyridin-...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C1CC1)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C22H28F2N2O/c1-14(2)12-22(3,25)13-27-20-7-6-16(10-18(20)15-4-5-15)17-8-9-26-19(11-17)21(23)24/h6-11,14-15,21H,4-5,12-13,25H2,1-3H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311336 ((S)-1-((2′-chloro-5-(difluoromethyl)-[3,4...) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C(F)F)-c1ccnc(Cl)c1 |r| Show InChI InChI=1S/C18H22ClF2N3O/c1-11(2)8-18(3,22)10-25-17-14(16(20)21)6-13(9-24-17)12-4-5-23-15(19)7-12/h4-7,9,11,16H,8,10,22H2,1-3H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50586144 (CHEMBL5074638) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C)-c1ccnc(c1)C(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311167 ((S)-2-((2-amino-4-methylpentyl)oxy)-5-(2-methoxypy...) Show SMILES COc1cc(ccn1)-c1ccc(OC[C@@H](N)CC(C)C)c(c1)C#N |r| Show InChI InChI=1S/C19H23N3O2/c1-13(2)8-17(21)12-24-18-5-4-14(9-16(18)11-20)15-6-7-22-19(10-15)23-3/h4-7,9-10,13,17H,8,12,21H2,1-3H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50586142 (CHEMBL5088767) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C)-c1ccnc(Cl)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311263 ((S)-1-((6-(difluoromethyl)-2′-methyl-[2,4...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(nc1C(F)F)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C19H25F2N3O/c1-12(2)10-19(4,22)11-25-16-6-5-15(24-17(16)18(20)21)14-7-8-23-13(3)9-14/h5-9,12,18H,10-11,22H2,1-4H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311211 ((S)-1-((6-chloro-2′-methyl-[2,4′-bipyr...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(nc1Cl)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C18H24ClN3O/c1-12(2)10-18(4,20)11-23-16-6-5-15(22-17(16)19)14-7-8-21-13(3)9-14/h5-9,12H,10-11,20H2,1-4H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311245 ((S)-6-((2-amino-2,4-dimethylpentyl)oxy)-2′-m...) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C#N)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C19H24N4O/c1-13(2)9-19(4,21)12-24-18-16(10-20)8-17(11-23-18)15-5-6-22-14(3)7-15/h5-8,11,13H,9,12,21H2,1-4H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311204 ((S)-2-((2-amino-2,4-dimethylpentyl)oxy)-5-(2-methy...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C#N)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C20H25N3O/c1-14(2)11-20(4,22)13-24-19-6-5-16(10-18(19)12-21)17-7-8-23-15(3)9-17/h5-10,14H,11,13,22H2,1-4H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311201 ((S)-2,4-dimethyl-1-(4-(2-methylpyridin-4-yl)-2-(tr...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C20H25F3N2O/c1-13(2)11-19(4,24)12-26-18-6-5-15(10-17(18)20(21,22)23)16-7-8-25-14(3)9-16/h5-10,13H,11-12,24H2,1-4H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311199 ((S)-2,4-dimethyl-1-(4-(pyridin-4-yl)-2-(trifluorom...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccncc1 |r| Show InChI InChI=1S/C19H23F3N2O/c1-13(2)11-18(3,23)12-25-17-5-4-15(10-16(17)19(20,21)22)14-6-8-24-9-7-14/h4-10,13H,11-12,23H2,1-3H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50586143 (CHEMBL5077192) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1Cl)-c1ccnc(C)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311209 ((S)-1-((2′,6-dimethyl-[2,4′-bipyridin]...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(nc1C)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C19H27N3O/c1-13(2)11-19(5,20)12-23-18-7-6-17(22-15(18)4)16-8-9-21-14(3)10-16/h6-10,13H,11-12,20H2,1-5H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311205 ((S)-1-(2-cyclopropyl-4-(2-methylpyridin-4-yl)pheno...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C1CC1)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C22H30N2O/c1-15(2)13-22(4,23)14-25-21-8-7-18(12-20(21)17-5-6-17)19-9-10-24-16(3)11-19/h7-12,15,17H,5-6,13-14,23H2,1-4H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50586141 (CHEMBL5079068) Show SMILES CC(C)C[C@H](N)COc1ccc(cc1)-c1ccncc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50586141 (CHEMBL5079068) Show SMILES CC(C)C[C@H](N)COc1ccc(cc1)-c1ccncc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311168 ((S)-2-((2-amino-4-methylpentyl)oxy)-5-(2-(trifluor...) Show SMILES CC(C)C[C@H](N)COc1ccc(cc1C#N)-c1ccnc(c1)C(F)(F)F |r| Show InChI InChI=1S/C19H20F3N3O/c1-12(2)7-16(24)11-26-17-4-3-13(8-15(17)10-23)14-5-6-25-18(9-14)19(20,21)22/h3-6,8-9,12,16H,7,11,24H2,1-2H3/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
Citron Rho-interacting kinase (Homo sapiens (Human))	BDBM311193 ((S)-1-(2-(difluoromethyl)-4-(2-(difluoromethyl)pyr...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)F)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C20H24F4N2O/c1-12(2)10-20(3,25)11-27-17-5-4-13(8-15(17)18(21)22)14-6-7-26-16(9-14)19(23)24/h4-9,12,18-19H,10-11,25H2,1-3H3/t20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CRIK (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
Cyclin-G-associated kinase (Homo sapiens (Human))	BDBM311193 ((S)-1-(2-(difluoromethyl)-4-(2-(difluoromethyl)pyr...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)F)-c1ccnc(c1)C(F)F |r| Show InChI InChI=1S/C20H24F4N2O/c1-12(2)10-20(3,25)11-27-17-5-4-13(8-15(17)18(21)22)14-6-7-26-16(9-14)19(23)24/h4-9,12,18-19H,10-11,25H2,1-3H3/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GAK (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311211 ((S)-1-((6-chloro-2′-methyl-[2,4′-bipyr...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(nc1Cl)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C18H24ClN3O/c1-12(2)10-18(4,20)11-23-16-6-5-15(22-17(16)19)14-7-8-21-13(3)9-14/h5-9,12H,10-11,20H2,1-4H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50586143 (CHEMBL5077192) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1Cl)-c1ccnc(C)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311166 ( (S)-2-((2-amino-4-methylpentyl)oxy)-5-(2-methylpy...) Show SMILES CC(C)C[C@H](N)COc1ccc(cc1C#N)-c1ccnc(C)c1 |r| Show InChI InChI=1S/C19H23N3O/c1-13(2)8-18(21)12-23-19-5-4-15(10-17(19)11-20)16-6-7-22-14(3)9-16/h4-7,9-10,13,18H,8,12,21H2,1-3H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311167 ((S)-2-((2-amino-4-methylpentyl)oxy)-5-(2-methoxypy...) Show SMILES COc1cc(ccn1)-c1ccc(OC[C@@H](N)CC(C)C)c(c1)C#N |r| Show InChI InChI=1S/C19H23N3O2/c1-13(2)8-17(21)12-24-18-5-4-14(9-16(18)11-20)15-6-7-22-19(10-15)23-3/h4-7,9-10,13,17H,8,12,21H2,1-3H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311168 ((S)-2-((2-amino-4-methylpentyl)oxy)-5-(2-(trifluor...) Show SMILES CC(C)C[C@H](N)COc1ccc(cc1C#N)-c1ccnc(c1)C(F)(F)F |r| Show InChI InChI=1S/C19H20F3N3O/c1-12(2)7-16(24)11-26-17-4-3-13(8-15(17)10-23)14-5-6-25-18(9-14)19(20,21)22/h3-6,8-9,12,16H,7,11,24H2,1-2H3/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50586140 (CHEMBL5081027) Show SMILES CC(C)C[C@@H](N)COc1ccc(cc1)-c1ccncc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair

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