Compile Data Set for Download or QSAR

Found 53 hits Enz. Inhib. hit(s) with all data for entry = 3369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31965 (carbohydrazide derivative, 5h) Show SMILES Oc1cc2ccccc2cc1C(=O)NN=Cc1cc(Br)c(O)c(Br)c1O |w:15.17| Show InChI InChI=1S/C18H12Br2N2O4/c19-13-6-11(16(24)15(20)17(13)25)8-21-22-18(26)12-5-9-3-1-2-4-10(9)7-14(12)23/h1-8,23-25H,(H,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31930 (carbohydrazide derivative, 3m) Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccc3ccccc3c2)c(O)c1Br Show InChI InChI=1S/C18H12Br2N2O3/c19-14-8-13(16(23)15(20)17(14)24)9-21-22-18(25)12-6-5-10-3-1-2-4-11(10)7-12/h1-9,23-24H,(H,22,25)/b21-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair				3D Structure (crystal)
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31927 (carbohydrazide derivative, 3j) Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccc(Br)cc2)c(O)c1Br Show InChI InChI=1S/C14H9Br3N2O3/c15-9-3-1-7(2-4-9)14(22)19-18-6-8-5-10(16)13(21)11(17)12(8)20/h1-6,20-21H,(H,19,22)/b18-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair				3D Structure (crystal)
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31926 (carbohydrazide derivative, 3i) Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccc(Cl)cc2)c(O)c1Br Show InChI InChI=1S/C14H9Br2ClN2O3/c15-10-5-8(12(20)11(16)13(10)21)6-18-19-14(22)7-1-3-9(17)4-2-7/h1-6,20-21H,(H,19,22)/b18-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair				3D Structure (crystal)
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31934 (carbohydrazide derivative, 3q) Show SMILES CC(C)(C)c1ccc(cc1)C(=O)N\N=C\c1cc(Br)c(O)c(Br)c1O Show InChI InChI=1S/C18H18Br2N2O3/c1-18(2,3)12-6-4-10(5-7-12)17(25)22-21-9-11-8-13(19)16(24)14(20)15(11)23/h4-9,23-24H,1-3H3,(H,22,25)/b21-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair				3D Structure (crystal)
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31964 (carbohydrazide derivative, 5g) Show SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc3ccccc3c2O)c(O)c1Br |w:6.5| Show InChI InChI=1S/C18H12Br2N2O4/c19-13-7-10(15(23)14(20)17(13)25)8-21-22-18(26)12-6-5-9-3-1-2-4-11(9)16(12)24/h1-8,23-25H,(H,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31928 (carbohydrazide derivative, 3k) Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2cccc(Br)c2)c(O)c1Br Show InChI InChI=1S/C14H9Br3N2O3/c15-9-3-1-2-7(4-9)14(22)19-18-6-8-5-10(16)13(21)11(17)12(8)20/h1-6,20-21H,(H,19,22)/b18-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair				3D Structure (crystal)
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31960 (carbohydrazide derivative, 5c) Show SMILES Oc1c(Br)cc(C=NNC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(O)c1Br |w:6.5| Show InChI InChI=1S/C16H8Br2F6N2O3/c17-10-3-7(12(27)11(18)13(10)28)5-25-26-14(29)6-1-8(15(19,20)21)4-9(2-6)16(22,23)24/h1-5,27-28H,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31967 (carbohydrazide derivative, 5j) Show SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc3cc(Br)ccc3c2)c(O)c1Br |w:6.5| Show InChI InChI=1S/C18H11Br3N2O3/c19-13-4-3-9-5-11(2-1-10(9)6-13)18(26)23-22-8-12-7-14(20)17(25)15(21)16(12)24/h1-8,24-25H,(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31963 (carbohydrazide derivative, 5f) Show SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc-3c(Cc4ccccc-34)c2)c(O)c1Br |w:6.5| Show InChI InChI=1S/C21H14Br2N2O3/c22-17-9-14(19(26)18(23)20(17)27)10-24-25-21(28)12-5-6-16-13(8-12)7-11-3-1-2-4-15(11)16/h1-6,8-10,26-27H,7H2,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31925 (carbohydrazide derivative, 3h) Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccc(F)cc2)c(O)c1Br Show InChI InChI=1S/C14H9Br2FN2O3/c15-10-5-8(12(20)11(16)13(10)21)6-18-19-14(22)7-1-3-9(17)4-2-7/h1-6,20-21H,(H,19,22)/b18-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.43E+3	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31966 (carbohydrazide derivative, 5i) Show SMILES Oc1ccc2cc(ccc2c1)C(=O)NN=Cc1cc(Br)c(O)c(Br)c1O |w:15.17| Show InChI InChI=1S/C18H12Br2N2O4/c19-14-7-12(16(24)15(20)17(14)25)8-21-22-18(26)11-2-1-10-6-13(23)4-3-9(10)5-11/h1-8,23-25H,(H,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31931 (carbohydrazide derivative, 3n) Show SMILES COc1ccc(cc1)C(=O)N\N=C\c1cc(Br)c(O)c(Br)c1O Show InChI InChI=1S/C15H12Br2N2O4/c1-23-10-4-2-8(3-5-10)15(22)19-18-7-9-6-11(16)14(21)12(17)13(9)20/h2-7,20-21H,1H3,(H,19,22)/b18-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	9.92E+3	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair				3D Structure (crystal)
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31961 (carbohydrazide derivative, 5d) Show SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc(Oc3ccccc3)cc2)c(O)c1Br |w:6.5| Show InChI InChI=1S/C20H14Br2N2O4/c21-16-10-13(18(25)17(22)19(16)26)11-23-24-20(27)12-6-8-15(9-7-12)28-14-4-2-1-3-5-14/h1-11,25-26H,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31917 (carbohydrazide derivative, 1) Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2cccnc2)c(O)c1Br Show InChI InChI=1S/C13H9Br2N3O3/c14-9-4-8(11(19)10(15)12(9)20)6-17-18-13(21)7-2-1-3-16-5-7/h1-6,19-20H,(H,18,21)/b17-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	3.98E+4	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair				3D Structure (crystal)
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31959 (carbohydrazide derivative, 5b) Show SMILES Oc1ccc(cc1)-c1ccc(cc1)C(=O)NN=Cc1cc(Br)c(O)c(Br)c1O |w:17.19| Show InChI InChI=1S/C20H14Br2N2O4/c21-16-9-14(18(26)17(22)19(16)27)10-23-24-20(28)13-3-1-11(2-4-13)12-5-7-15(25)8-6-12/h1-10,25-27H,(H,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31941 (1,3-thiazolidin-5-ylidene derivative, 4e) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccc(OC)cc1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(O)=O Show InChI InChI=1S/C25H21ClN2O6S/c1-32-12-11-28-23(29)22(35-25(28)27-16-4-6-17(33-2)7-5-16)14-18-8-10-21(34-18)15-3-9-20(26)19(13-15)24(30)31/h3-10,13-14H,11-12H2,1-2H3,(H,30,31)/b22-14+,27-25+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31943 (1,3-thiazolidin-5-ylidene derivative, 4g) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccccc1Br)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C25H20BrClN2O5S/c1-32-12-11-29-23(30)22(35-25(29)28-20-6-4-3-5-18(20)26)14-16-8-10-21(34-16)15-7-9-19(27)17(13-15)24(31)33-2/h3-10,13-14H,11-12H2,1-2H3/b22-14+,28-25+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31944 (1,3-thiazolidin-5-ylidene derivative, 4h) Show SMILES COCCN1C(=O)\C(S\C1=N\c1cccc(Br)c1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C25H20BrClN2O5S/c1-32-11-10-29-23(30)22(35-25(29)28-17-5-3-4-16(26)13-17)14-18-7-9-21(34-18)15-6-8-20(27)19(12-15)24(31)33-2/h3-9,12-14H,10-11H2,1-2H3/b22-14+,28-25+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31945 (1,3-thiazolidin-5-ylidene derivative, 4i) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccc2ccccc2c1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C29H23ClN2O5S/c1-35-14-13-32-27(33)26(38-29(32)31-21-9-7-18-5-3-4-6-19(18)15-21)17-22-10-12-25(37-22)20-8-11-24(30)23(16-20)28(34)36-2/h3-12,15-17H,13-14H2,1-2H3/b26-17+,31-29+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31946 (1,3-thiazolidin-5-ylidene derivative, 4j) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccc2ccccc2c1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(O)=O Show InChI InChI=1S/C28H21ClN2O5S/c1-35-13-12-31-26(32)25(37-28(31)30-20-8-6-17-4-2-3-5-18(17)14-20)16-21-9-11-24(36-21)19-7-10-23(29)22(15-19)27(33)34/h2-11,14-16H,12-13H2,1H3,(H,33,34)/b25-16+,30-28+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31947 (1,3-thiazolidin-5-ylidene derivative, 4k) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccc(cc1)C(F)(F)F)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C26H20ClF3N2O5S/c1-35-12-11-32-23(33)22(38-25(32)31-17-6-4-16(5-7-17)26(28,29)30)14-18-8-10-21(37-18)15-3-9-20(27)19(13-15)24(34)36-2/h3-10,13-14H,11-12H2,1-2H3/b22-14+,31-25+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31948 (1,3-thiazolidin-5-ylidene derivative, 4l) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccccc1C(F)(F)F)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C26H20ClF3N2O5S/c1-35-12-11-32-23(33)22(38-25(32)31-20-6-4-3-5-18(20)26(28,29)30)14-16-8-10-21(37-16)15-7-9-19(27)17(13-15)24(34)36-2/h3-10,13-14H,11-12H2,1-2H3/b22-14+,31-25+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31949 (1,3-thiazolidin-5-ylidene derivative, 4m) Show SMILES COCCN1C(=O)\C(S\C1=N\c1cccc(c1)C(F)(F)F)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C26H20ClF3N2O5S/c1-35-11-10-32-23(33)22(38-25(32)31-17-5-3-4-16(13-17)26(28,29)30)14-18-7-9-21(37-18)15-6-8-20(27)19(12-15)24(34)36-2/h3-9,12-14H,10-11H2,1-2H3/b22-14+,31-25+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31950 (1,3-thiazolidin-5-ylidene derivative, 4n) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccccc1OC)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C26H23ClN2O6S/c1-32-13-12-29-24(30)23(36-26(29)28-20-6-4-5-7-22(20)33-2)15-17-9-11-21(35-17)16-8-10-19(27)18(14-16)25(31)34-3/h4-11,14-15H,12-13H2,1-3H3/b23-15+,28-26+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31951 (1,3-thiazolidin-5-ylidene derivative, 4o) Show SMILES COCCN1C(=O)\C(S\C1=N\c1cccc(OC)c1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C26H23ClN2O6S/c1-32-12-11-29-24(30)23(36-26(29)28-17-5-4-6-18(14-17)33-2)15-19-8-10-22(35-19)16-7-9-21(27)20(13-16)25(31)34-3/h4-10,13-15H,11-12H2,1-3H3/b23-15+,28-26+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31952 (1,3-thiazolidin-5-ylidene derivative, 4p) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccc(F)cc1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C25H20ClFN2O5S/c1-32-12-11-29-23(30)22(35-25(29)28-17-6-4-16(27)5-7-17)14-18-8-10-21(34-18)15-3-9-20(26)19(13-15)24(31)33-2/h3-10,13-14H,11-12H2,1-2H3/b22-14+,28-25+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31953 (1,3-thiazolidin-5-ylidene derivative, 4q) Show SMILES COCCN1C(=O)\C(S\C1=N\c1cccc(F)c1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C25H20ClFN2O5S/c1-32-11-10-29-23(30)22(35-25(29)28-17-5-3-4-16(27)13-17)14-18-7-9-21(34-18)15-6-8-20(26)19(12-15)24(31)33-2/h3-9,12-14H,10-11H2,1-2H3/b22-14+,28-25+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31954 (1,3-thiazolidin-5-ylidene derivative, 4r) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccccc1F)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C25H20ClFN2O5S/c1-32-12-11-29-23(30)22(35-25(29)28-20-6-4-3-5-19(20)27)14-16-8-10-21(34-16)15-7-9-18(26)17(13-15)24(31)33-2/h3-10,13-14H,11-12H2,1-2H3/b22-14+,28-25+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31955 (1,3-thiazolidin-5-ylidene derivative, 4s) Show SMILES COC(=O)c1cc(ccc1Cl)-c1ccc(\C=C2\S\C(=N\c3ccccc3)N(CCCN(C)C)C2=O)o1 Show InChI InChI=1S/C27H26ClN3O4S/c1-30(2)14-7-15-31-25(32)24(36-27(31)29-19-8-5-4-6-9-19)17-20-11-13-23(35-20)18-10-12-22(28)21(16-18)26(33)34-3/h4-6,8-13,16-17H,7,14-15H2,1-3H3/b24-17+,29-27+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31956 (1,3-thiazolidin-5-ylidene derivative, 4t) Show SMILES CCN(CC)CCN1C(=O)\C(S\C1=N\c1ccccc1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C28H28ClN3O4S/c1-4-31(5-2)15-16-32-26(33)25(37-28(32)30-20-9-7-6-8-10-20)18-21-12-14-24(36-21)19-11-13-23(29)22(17-19)27(34)35-3/h6-14,17-18H,4-5,15-16H2,1-3H3/b25-18+,30-28+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31957 (1,3-thiazolidin-5-ylidene derivative, 4u) Show SMILES COC(=O)c1cc(ccc1Cl)-c1ccc(\C=C2\S\C(=N\c3ccccc3)N(CCN3CCCC3)C2=O)o1 Show InChI InChI=1S/C28H26ClN3O4S/c1-35-27(34)22-17-19(9-11-23(22)29)24-12-10-21(36-24)18-25-26(33)32(16-15-31-13-5-6-14-31)28(37-25)30-20-7-3-2-4-8-20/h2-4,7-12,17-18H,5-6,13-16H2,1H3/b25-18+,30-28+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31958 (carbohydrazide derivative, 5a) Show SMILES Oc1ccc(cc1)C(=O)NN=Cc1cc(Br)c(O)c(Br)c1O |w:11.12| Show InChI InChI=1S/C14H10Br2N2O4/c15-10-5-8(12(20)11(16)13(10)21)6-17-18-14(22)7-1-3-9(19)4-2-7/h1-6,19-21H,(H,18,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31962 (carbohydrazide derivative, 5e) Show SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc(cc2)-c2ccccc2)c(O)c1Br |w:6.5| Show InChI InChI=1S/C20H14Br2N2O3/c21-16-10-15(18(25)17(22)19(16)26)11-23-24-20(27)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-11,25-26H,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31968 (trimethoxybenzyl thiourea, 5k) Show SMILES COc1cc(CNC(=S)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc(OC)c1OC Show InChI InChI=1S/C19H18F6N2O3S/c1-28-14-4-10(5-15(29-2)16(14)30-3)9-26-17(31)27-13-7-11(18(20,21)22)6-12(8-13)19(23,24)25/h4-8H,9H2,1-3H3,(H2,26,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31969 (trimethoxyphenyl prop-2-enamide, 5l) Show SMILES COc1ccc(\C=C\C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(OC)c1OC Show InChI InChI=1S/C20H17F6NO4/c1-29-15-6-4-11(17(30-2)18(15)31-3)5-7-16(28)27-14-9-12(19(21,22)23)8-13(10-14)20(24,25)26/h4-10H,1-3H3,(H,27,28)/b7-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31940 (1,3-thiazolidin-5-ylidene derivative, 4d) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccc(OC)cc1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C26H23ClN2O6S/c1-32-13-12-29-24(30)23(36-26(29)28-17-5-7-18(33-2)8-6-17)15-19-9-11-22(35-19)16-4-10-21(27)20(14-16)25(31)34-3/h4-11,14-15H,12-13H2,1-3H3/b23-15+,28-26+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31939 (1,3-thiazolidin-5-ylidene derivative, 4c) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccccc1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC Show InChI InChI=1S/C25H21ClN2O5S/c1-31-13-12-28-23(29)22(34-25(28)27-17-6-4-3-5-7-17)15-18-9-11-21(33-18)16-8-10-20(26)19(14-16)24(30)32-2/h3-11,14-15H,12-13H2,1-2H3/b22-15+,27-25+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31938 (1,3-thiazolidin-5-ylidene derivative, 4b) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccccc1)=C/c1ccc(o1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H19ClN2O3S/c1-28-14-13-26-22(27)21(30-23(26)25-18-5-3-2-4-6-18)15-19-11-12-20(29-19)16-7-9-17(24)10-8-16/h2-12,15H,13-14H2,1H3/b21-15+,25-23+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31937 (1,3-thiazolidin-5-ylidene derivative, 4a) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccccc1)=C/c1ccc(o1)-c1cc(ccc1Cl)C(=O)OC Show InChI InChI=1S/C25H21ClN2O5S/c1-31-13-12-28-23(29)22(34-25(28)27-17-6-4-3-5-7-17)15-18-9-11-21(33-18)19-14-16(24(30)32-2)8-10-20(19)26/h3-11,14-15H,12-13H2,1-2H3/b22-15+,27-25+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31936 (1,3-thiazolidin-5-ylidene derivative, 2) Show SMILES COCCN1C(=O)\C(S\C1=N\c1ccccc1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(O)=O Show InChI InChI=1S/C24H19ClN2O5S/c1-31-12-11-27-22(28)21(33-24(27)26-16-5-3-2-4-6-16)14-17-8-10-20(32-17)15-7-9-19(25)18(13-15)23(29)30/h2-10,13-14H,11-12H2,1H3,(H,29,30)/b21-14+,26-24+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair				3D Structure (crystal)
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31935 (carbohydrazide derivative, 3r) Show SMILES Oc1ccc(CC(=O)N\N=C\c2cc(Br)c(O)c(Br)c2O)cc1 Show InChI InChI=1S/C15H12Br2N2O4/c16-11-6-9(14(22)13(17)15(11)23)7-18-19-12(21)5-8-1-3-10(20)4-2-8/h1-4,6-7,20,22-23H,5H2,(H,19,21)/b18-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31933 (carbohydrazide derivative, 3p) Show SMILES CC(=O)N\N=C\c1cc(Br)c(O)c(Br)c1O Show InChI InChI=1S/C9H8Br2N2O3/c1-4(14)13-12-3-5-2-6(10)9(16)7(11)8(5)15/h2-3,15-16H,1H3,(H,13,14)/b12-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31932 (carbohydrazide derivative, 3o) Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccncc2)c(O)c1Br Show InChI InChI=1S/C13H9Br2N3O3/c14-9-5-8(11(19)10(15)12(9)20)6-17-18-13(21)7-1-3-16-4-2-7/h1-6,19-20H,(H,18,21)/b17-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31929 (carbohydrazide derivative, 3l) Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2cccs2)c(O)c1Br Show InChI InChI=1S/C12H8Br2N2O3S/c13-7-4-6(10(17)9(14)11(7)18)5-15-16-12(19)8-2-1-3-20-8/h1-5,17-18H,(H,16,19)/b15-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31924 (carbohydrazide derivative, 3g) Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2cccc(F)c2)c(O)c1Br Show InChI InChI=1S/C14H9Br2FN2O3/c15-10-5-8(12(20)11(16)13(10)21)6-18-19-14(22)7-2-1-3-9(17)4-7/h1-6,20-21H,(H,19,22)/b18-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31923 (carbohydrazide derivative, 3f) Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccco2)c(O)c1Br Show InChI InChI=1S/C12H8Br2N2O4/c13-7-4-6(10(17)9(14)11(7)18)5-15-16-12(19)8-2-1-3-20-8/h1-5,17-18H,(H,16,19)/b15-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31922 (carbohydrazide derivative, 3e) Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccccc2)c(O)c1Br Show InChI InChI=1S/C14H10Br2N2O3/c15-10-6-9(12(19)11(16)13(10)20)7-17-18-14(21)8-4-2-1-3-5-8/h1-7,19-20H,(H,18,21)/b17-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31921 (carbohydrazide derivative, 3d) Show SMILES COc1c(Br)cc(\C=N\NC(=O)c2cccnc2)c(OC)c1Br Show InChI InChI=1S/C15H13Br2N3O3/c1-22-13-10(6-11(16)14(23-2)12(13)17)8-19-20-15(21)9-4-3-5-18-7-9/h3-8H,1-2H3,(H,20,21)/b19-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Helicobacter pylori (Campylobacter pylori))	BDBM31920 (carbohydrazide derivative, 3c) Show SMILES Oc1ccc(\C=N\NC(=O)c2cccnc2)cc1 Show InChI InChI=1S/C13H11N3O2/c17-12-5-3-10(4-6-12)8-15-16-13(18)11-2-1-7-14-9-11/h1-9,17H,(H,16,18)/b15-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	25
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair

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