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Compile Data Set for Download or QSAR

Found 96 hits Enz. Inhib. hit(s) with all data for entry = 1704   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kallikrein-7


(Homo sapiens (Human))
BDBM336124
PNG
(US9744148, 1)
Show SMILES CC(OC(=O)Cc1ccc(Cl)cc1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C15H15ClN2O4/c1-9-7-13(18-22-9)17-15(20)10(2)21-14(19)8-11-3-5-12(16)6-4-11/h3-7,10H,8H2,1-2H3,(H,17,18,20)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336128
PNG
(US9744148, 2)
Show SMILES CC(OC(=O)Cc1ccc(Cl)cc1)C(=O)Nc1ccc(F)cc1
Show InChI InChI=1S/C17H15ClFNO3/c1-11(17(22)20-15-8-6-14(19)7-9-15)23-16(21)10-12-2-4-13(18)5-3-12/h2-9,11H,10H2,1H3,(H,20,22)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336129
PNG
(US9744148, 3)
Show SMILES CCC(OC(=O)Cc1ccc(Cl)cc1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C16H17ClN2O4/c1-3-13(16(21)18-14-8-10(2)23-19-14)22-15(20)9-11-4-6-12(17)7-5-11/h4-8,13H,3,9H2,1-2H3,(H,18,19,21)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336130
PNG
(US9744148, 4)
Show SMILES COc1ccc(NC(=O)C(C)OC(=O)Cc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C18H18ClNO4/c1-12(18(22)20-15-7-9-16(23-2)10-8-15)24-17(21)11-13-3-5-14(19)6-4-13/h3-10,12H,11H2,1-2H3,(H,20,22)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336132
PNG
(US9744148, 5)
Show SMILES CC(OC(=O)Cc1ccc(Cl)cc1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C17H16ClNO3/c1-12(17(21)19-15-5-3-2-4-6-15)22-16(20)11-13-7-9-14(18)10-8-13/h2-10,12H,11H2,1H3,(H,19,21)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336133
PNG
(US9744148, 6)
Show SMILES CCC(OC(=O)Cc1ccc(Cl)cc1)C(=O)Nc1ccc(OC)cc1
Show InChI InChI=1S/C19H20ClNO4/c1-3-17(19(23)21-15-8-10-16(24-2)11-9-15)25-18(22)12-13-4-6-14(20)7-5-13/h4-11,17H,3,12H2,1-2H3,(H,21,23)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336134
PNG
(US9744148, 7)
Show SMILES COc1ccc(CC(=O)OC(C)C(=O)Nc2cc(C)on2)cc1
Show InChI InChI=1S/C16H18N2O5/c1-10-8-14(18-23-10)17-16(20)11(2)22-15(19)9-12-4-6-13(21-3)7-5-12/h4-8,11H,9H2,1-3H3,(H,17,18,20)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336135
PNG
(US9744148, 8)
Show SMILES CCC(OC(=O)Cc1ccc(Cl)cc1)C(=O)Nc1ccc(F)cc1
Show InChI InChI=1S/C18H17ClFNO3/c1-2-16(18(23)21-15-9-7-14(20)8-10-15)24-17(22)11-12-3-5-13(19)6-4-12/h3-10,16H,2,11H2,1H3,(H,21,23)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336138
PNG
(US9744148, 11)
Show SMILES CCC(OC(=O)CCC1CCCC1)C(=O)Nc1ccc(OC)cc1
Show InChI InChI=1S/C19H27NO4/c1-3-17(24-18(21)13-8-14-6-4-5-7-14)19(22)20-15-9-11-16(23-2)12-10-15/h9-12,14,17H,3-8,13H2,1-2H3,(H,20,22)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336137
PNG
(US9744148, 10 | US9744148, 31)
Show SMILES CC(OC(=O)CCC1CCCC1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C17H23NO3/c1-13(17(20)18-15-9-3-2-4-10-15)21-16(19)12-11-14-7-5-6-8-14/h2-4,9-10,13-14H,5-8,11-12H2,1H3,(H,18,20)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336136
PNG
(US9744148, 9)
Show SMILES CCC(OC(=O)Cc1ccc(Cl)cc1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C18H18ClNO3/c1-2-16(18(22)20-15-6-4-3-5-7-15)23-17(21)12-13-8-10-14(19)11-9-13/h3-11,16H,2,12H2,1H3,(H,20,22)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336142
PNG
(US9744148, 12 | US9744148, 23)
Show SMILES CCC(OC(=O)Cc1ccc(OC)cc1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C17H20N2O5/c1-4-14(17(21)18-15-9-11(2)24-19-15)23-16(20)10-12-5-7-13(22-3)8-6-12/h5-9,14H,4,10H2,1-3H3,(H,18,19,21)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336143
PNG
(US9744148, 13)
Show SMILES COc1ccc(NC(=O)C(OC(=O)Cc2ccc(Cl)cc2)c2ccccc2)cc1
Show InChI InChI=1S/C23H20ClNO4/c1-28-20-13-11-19(12-14-20)25-23(27)22(17-5-3-2-4-6-17)29-21(26)15-16-7-9-18(24)10-8-16/h2-14,22H,15H2,1H3,(H,25,27)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336145
PNG
(US9744148, 14)
Show SMILES CC(OC(=O)CCC1CCCC1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C15H22N2O4/c1-10-9-13(17-21-10)16-15(19)11(2)20-14(18)8-7-12-5-3-4-6-12/h9,11-12H,3-8H2,1-2H3,(H,16,17,19)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336146
PNG
(US9744148, 15)
Show SMILES COc1ccc(CC(=O)OC(C)C(=O)Nc2ccc(OC)cc2)cc1
Show InChI InChI=1S/C19H21NO5/c1-13(19(22)20-15-6-10-17(24-3)11-7-15)25-18(21)12-14-4-8-16(23-2)9-5-14/h4-11,13H,12H2,1-3H3,(H,20,22)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336147
PNG
(US9744148, 16)
Show SMILES CCC(OC(=O)CCC1CCCC1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C16H24N2O4/c1-3-13(16(20)17-14-10-11(2)22-18-14)21-15(19)9-8-12-6-4-5-7-12/h10,12-13H,3-9H2,1-2H3,(H,17,18,20)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336148
PNG
(US9744148, 17)
Show SMILES Cc1cc(NC(=O)C(OC(=O)Cc2ccc(Cl)cc2)c2ccccc2)no1
Show InChI InChI=1S/C20H17ClN2O4/c1-13-11-17(23-27-13)22-20(25)19(15-5-3-2-4-6-15)26-18(24)12-14-7-9-16(21)10-8-14/h2-11,19H,12H2,1H3,(H,22,23,25)
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SIXERA Pharma AB

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Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336149
PNG
(US9744148, 18)
Show SMILES CCCC(OC(=O)C(c1ccccc1)c1ccccc1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C23H24N2O4/c1-3-10-19(22(26)24-20-15-16(2)29-25-20)28-23(27)21(17-11-6-4-7-12-17)18-13-8-5-9-14-18/h4-9,11-15,19,21H,3,10H2,1-2H3,(H,24,25,26)
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SIXERA Pharma AB

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Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336150
PNG
(US9744148, 19)
Show SMILES COc1ccc(NC(=O)C(OC(=O)CCC2CCCC2)c2ccccc2)cc1
Show InChI InChI=1S/C23H27NO4/c1-27-20-14-12-19(13-15-20)24-23(26)22(18-9-3-2-4-10-18)28-21(25)16-11-17-7-5-6-8-17/h2-4,9-10,12-15,17,22H,5-8,11,16H2,1H3,(H,24,26)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336151
PNG
(US9744148, 20)
Show SMILES Cc1cc(NC(=O)C(OC(=O)CCC2CCCC2)c2ccccc2)no1
Show InChI InChI=1S/C20H24N2O4/c1-14-13-17(22-26-14)21-20(24)19(16-9-3-2-4-10-16)25-18(23)12-11-15-7-5-6-8-15/h2-4,9-10,13,15,19H,5-8,11-12H2,1H3,(H,21,22,24)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336152
PNG
(US9744148, 21)
Show SMILES COc1ccc(CC(=O)OC(C)C(=O)Nc2ccccc2)cc1
Show InChI InChI=1S/C18H19NO4/c1-13(18(21)19-15-6-4-3-5-7-15)23-17(20)12-14-8-10-16(22-2)11-9-14/h3-11,13H,12H2,1-2H3,(H,19,21)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336153
PNG
(US9744148, 22)
Show SMILES CC(OC(=O)CCC1CCCC1)C(=O)Nc1ccc(F)cc1
Show InChI InChI=1S/C17H22FNO3/c1-12(17(21)19-15-9-7-14(18)8-10-15)22-16(20)11-6-13-4-2-3-5-13/h7-10,12-13H,2-6,11H2,1H3,(H,19,21)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336142
PNG
(US9744148, 12 | US9744148, 23)
Show SMILES CCC(OC(=O)Cc1ccc(OC)cc1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C17H20N2O5/c1-4-14(17(21)18-15-9-11(2)24-19-15)23-16(20)10-12-5-7-13(22-3)8-6-12/h5-9,14H,4,10H2,1-3H3,(H,18,19,21)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336155
PNG
(US9744148, 24)
Show SMILES CCC(OC(=O)Cc1ccc(OC)cc1)C(=O)Nc1ccc(OC)cc1
Show InChI InChI=1S/C20H23NO5/c1-4-18(20(23)21-15-7-11-17(25-3)12-8-15)26-19(22)13-14-5-9-16(24-2)10-6-14/h5-12,18H,4,13H2,1-3H3,(H,21,23)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336156
PNG
(US9744148, 25)
Show SMILES CCC(OC(=O)CCC1CCCC1)C(=O)Nc1ccc(F)cc1
Show InChI InChI=1S/C18H24FNO3/c1-2-16(18(22)20-15-10-8-14(19)9-11-15)23-17(21)12-7-13-5-3-4-6-13/h8-11,13,16H,2-7,12H2,1H3,(H,20,22)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336157
PNG
(US9744148, 26)
Show SMILES CCC(OC(=O)Cc1ccc2OCOc2c1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C17H18N2O6/c1-3-12(17(21)18-15-6-10(2)25-19-15)24-16(20)8-11-4-5-13-14(7-11)23-9-22-13/h4-7,12H,3,8-9H2,1-2H3,(H,18,19,21)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336158
PNG
(US9744148, 27)
Show SMILES CCCCC(OC(=O)C(c1ccccc1)c1ccccc1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C24H26N2O4/c1-3-4-15-20(23(27)25-21-16-17(2)30-26-21)29-24(28)22(18-11-7-5-8-12-18)19-13-9-6-10-14-19/h5-14,16,20,22H,3-4,15H2,1-2H3,(H,25,26,27)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336159
PNG
(US9744148, 28)
Show SMILES CC[C@H](OC(=O)C(c1ccccc1)c1ccccc1)C(=O)Nc1cc(C)on1 |r|
Show InChI InChI=1S/C22H22N2O4/c1-3-18(21(25)23-19-14-15(2)28-24-19)27-22(26)20(16-10-6-4-7-11-16)17-12-8-5-9-13-17/h4-14,18,20H,3H2,1-2H3,(H,23,24,25)/t18-/m0/s1
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336160
PNG
(US9744148, 29)
Show SMILES Fc1ccc(NC(=O)C(OC(=O)Cc2ccc(Cl)cc2)c2ccccc2)cc1
Show InChI InChI=1S/C22H17ClFNO3/c23-17-8-6-15(7-9-17)14-20(26)28-21(16-4-2-1-3-5-16)22(27)25-19-12-10-18(24)11-13-19/h1-13,21H,14H2,(H,25,27)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336161
PNG
(US9744148, 30)
Show SMILES CCC(OC(=O)Cc1ccc(OC)cc1)C(=O)Nc1ccc(F)cc1
Show InChI InChI=1S/C19H20FNO4/c1-3-17(19(23)21-15-8-6-14(20)7-9-15)25-18(22)12-13-4-10-16(24-2)11-5-13/h4-11,17H,3,12H2,1-2H3,(H,21,23)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336137
PNG
(US9744148, 10 | US9744148, 31)
Show SMILES CC(OC(=O)CCC1CCCC1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C17H23NO3/c1-13(17(20)18-15-9-3-2-4-10-15)21-16(19)12-11-14-7-5-6-8-14/h2-4,9-10,13-14H,5-8,11-12H2,1H3,(H,18,20)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336163
PNG
(US9744148, 32)
Show SMILES Clc1ccc(CC(=O)OC(C(=O)Nc2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C22H18ClNO3/c23-18-13-11-16(12-14-18)15-20(25)27-21(17-7-3-1-4-8-17)22(26)24-19-9-5-2-6-10-19/h1-14,21H,15H2,(H,24,26)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336164
PNG
(US9744148, 33)
Show SMILES CCC(OC(=O)C(c1ccccc1)c1ccccc1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C22H22N2O4/c1-3-18(21(25)23-19-14-15(2)28-24-19)27-22(26)20(16-10-6-4-7-11-16)17-12-8-5-9-13-17/h4-14,18,20H,3H2,1-2H3,(H,23,24,25)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336165
PNG
(US9744148, 34)
Show SMILES CCC(OC(=O)Cc1ccc(OC)cc1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C19H21NO4/c1-3-17(19(22)20-15-7-5-4-6-8-15)24-18(21)13-14-9-11-16(23-2)12-10-14/h4-12,17H,3,13H2,1-2H3,(H,20,22)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336166
PNG
(US9744148, 35)
Show SMILES COc1ccc(CC(=O)OC(C(=O)Nc2ccc(OC)cc2)c2ccccc2)cc1
Show InChI InChI=1S/C24H23NO5/c1-28-20-12-8-17(9-13-20)16-22(26)30-23(18-6-4-3-5-7-18)24(27)25-19-10-14-21(29-2)15-11-19/h3-15,23H,16H2,1-2H3,(H,25,27)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336167
PNG
(US9744148, 36)
Show SMILES COc1ccc(CC(=O)OC(C(=O)Nc2cc(C)on2)c2ccccc2)cc1
Show InChI InChI=1S/C21H20N2O5/c1-14-12-18(23-28-14)22-21(25)20(16-6-4-3-5-7-16)27-19(24)13-15-8-10-17(26-2)11-9-15/h3-12,20H,13H2,1-2H3,(H,22,23,25)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336168
PNG
(US9744148, 37)
Show SMILES O=C(CCC1CCCC1)OC(C(=O)NCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H27NO3/c25-21(16-15-18-9-7-8-10-18)27-22(20-13-5-2-6-14-20)23(26)24-17-19-11-3-1-4-12-19/h1-6,11-14,18,22H,7-10,15-17H2,(H,24,26)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336169
PNG
(US9744148, 38)
Show SMILES COCCC(OC(=O)C(c1ccccc1)c1ccccc1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C23H24N2O5/c1-16-15-20(25-30-16)24-22(26)19(13-14-28-2)29-23(27)21(17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-12,15,19,21H,13-14H2,1-2H3,(H,24,25,26)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336170
PNG
(US9744148, 39)
Show SMILES CCC(OC(=O)Cc1ccc(Cl)c(Cl)c1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C16H16Cl2N2O4/c1-3-13(16(22)19-14-6-9(2)24-20-14)23-15(21)8-10-4-5-11(17)12(18)7-10/h4-7,13H,3,8H2,1-2H3,(H,19,20,22)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336171
PNG
(US9744148, 40)
Show SMILES COc1ccc(NC(=O)COC(=O)Cc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C17H16ClNO4/c1-22-15-8-6-14(7-9-15)19-16(20)11-23-17(21)10-12-2-4-13(18)5-3-12/h2-9H,10-11H2,1H3,(H,19,20)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336172
PNG
(US9744148, 41)
Show SMILES CCC(OC(=O)Cc1ccc(OC)c(OC)c1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C18H22N2O6/c1-5-13(18(22)19-16-8-11(2)26-20-16)25-17(21)10-12-6-7-14(23-3)15(9-12)24-4/h6-9,13H,5,10H2,1-4H3,(H,19,20,22)
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n/an/a 580n/an/an/an/an/an/a



SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336173
PNG
(US9744148, 42)
Show SMILES COc1ccc(CC(=O)OC(C)C(=O)Nc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H18FNO4/c1-12(18(22)20-15-7-5-14(19)6-8-15)24-17(21)11-13-3-9-16(23-2)10-4-13/h3-10,12H,11H2,1-2H3,(H,20,22)
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n/an/a 590n/an/an/an/an/an/a



SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336174
PNG
(US9744148, 43)
Show SMILES CCC(OC(=O)C(c1ccccc1)c1ccccc1)C(=O)Nc1ccc(OC)cc1
Show InChI InChI=1S/C25H25NO4/c1-3-22(24(27)26-20-14-16-21(29-2)17-15-20)30-25(28)23(18-10-6-4-7-11-18)19-12-8-5-9-13-19/h4-17,22-23H,3H2,1-2H3,(H,26,27)
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n/an/a 630n/an/an/an/an/an/a



SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336175
PNG
(US9744148, 44)
Show SMILES CCC(OC(=O)C(c1ccccc1)c1ccccc1)C(=O)Nc1ccc(F)cc1
Show InChI InChI=1S/C24H22FNO3/c1-2-21(23(27)26-20-15-13-19(25)14-16-20)29-24(28)22(17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-16,21-22H,2H2,1H3,(H,26,27)
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n/an/a 640n/an/an/an/an/an/a



SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336176
PNG
(US9744148, 45 | US9744148, 85)
Show SMILES CCC(OC(=O)C(NC(=O)c1ccccc1)c1ccccc1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C23H23N3O5/c1-3-18(22(28)24-19-14-15(2)31-26-19)30-23(29)20(16-10-6-4-7-11-16)25-21(27)17-12-8-5-9-13-17/h4-14,18,20H,3H2,1-2H3,(H,25,27)(H,24,26,28)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336177
PNG
(US9744148, 46)
Show SMILES COc1ccc(NC(=O)COC(=O)CCC2CCCC2)cc1
Show InChI InChI=1S/C17H23NO4/c1-21-15-9-7-14(8-10-15)18-16(19)12-22-17(20)11-6-13-4-2-3-5-13/h7-10,13H,2-6,11-12H2,1H3,(H,18,19)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336178
PNG
(US9744148, 47)
Show SMILES CC(OC(=O)C(c1ccccc1)c1ccccc1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C21H20N2O4/c1-14-13-18(23-27-14)22-20(24)15(2)26-21(25)19(16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-13,15,19H,1-2H3,(H,22,23,24)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336179
PNG
(US9744148, 48)
Show SMILES CCC(OC(=O)C(c1ccccc1)c1ccccc1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C24H23NO3/c1-2-21(23(26)25-20-16-10-5-11-17-20)28-24(27)22(18-12-6-3-7-13-18)19-14-8-4-9-15-19/h3-17,21-22H,2H2,1H3,(H,25,26)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336180
PNG
(US9744148, 49)
Show SMILES Cc1cc(NC(=O)C(OC(=O)C(NC(=O)c2ccccc2)c2ccccc2)c2ccccc2)no1
Show InChI InChI=1S/C27H23N3O5/c1-18-17-22(30-35-18)28-26(32)24(20-13-7-3-8-14-20)34-27(33)23(19-11-5-2-6-12-19)29-25(31)21-15-9-4-10-16-21/h2-17,23-24H,1H3,(H,29,31)(H,28,30,32)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
Kallikrein-7


(Homo sapiens (Human))
BDBM336181
PNG
(US9744148, 50)
Show SMILES Fc1ccc(NC(=O)COC(=O)Cc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C16H13ClFNO3/c17-12-3-1-11(2-4-12)9-16(21)22-10-15(20)19-14-7-5-13(18)6-8-14/h1-8H,9-10H2,(H,19,20)
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SIXERA Pharma AB

US Patent


Assay Description
Substrate:(MeO-Suc-Arg-Pro-Tyr-pNA), acetate salt, Peptide international, lot #906841, previously named S-2586Enzyme: Active human KLK7 (SCCE) 0.62 m...


US Patent US9744148 (2017)


BindingDB Entry DOI: 10.7270/Q2TH8PSV
More data for this
Ligand-Target Pair
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