Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4683 (4-Anilinoquinazoline 30 | N-(4-bromo-2-fluoropheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4682 (4-Anilinoquinazoline 29 | N-(4-chloro-2-fluorophen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4680 (4-Anilinoquinazoline 27 | N-(4-Bromo-2-fluoropheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4645 (4-Anilinoquinazoline 13 | Anilinoquinazoline deriv...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4671 (4-Anilinoquinazoline 18 | 4-fluoro-5-({6-methoxy-7...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4628 (Anilinoquinazoline deriv. 11 | CHEMBL286160 | KDR ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4670 (2-chloro-4-fluoro-5-({6-methoxy-7-[(1-methylpiperi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4664 (4-Anilinoquinazoline 11 | N-(4-Bromo-2-fluoropheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4658 (4-Anilinoquinazoline 5 | N-(4-bromo-2-fluorophenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4639 (4-Anilinoquinazoline 7 | Anilinoquinazoline deriv....) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4673 (4-Anilinoquinazoline 20 | N-(4-bromo-2,6-difluorop...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4684 (4-Anilinoquinazoline 31 | N-(4-bromo-2-fluoropheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4668 (4-Anilinoquinazoline 15 | N-(4-chloro-2-fluorophen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4678 (4-Anilinoquinazoline 25 | N-(4-bromo-2,6-difluorop...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4657 (4-Anilinoquinazoline 4 | N-(4-Chloro-2-fluoropheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human)) | BDBM4670 (2-chloro-4-fluoro-5-({6-methoxy-7-[(1-methylpiperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4669 (4-Anilinoquinazoline 16 | N-(2-fluoro-4-methylphen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human)) | BDBM4671 (4-Anilinoquinazoline 18 | 4-fluoro-5-({6-methoxy-7...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4672 (4-Anilinoquinazoline 19 | N-(4-Chloro-2,6-difluoro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4651 (N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[2-(1H-1,2,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4659 (4-Anilinoquinazoline 6 | N-(4-Chloro-2-fluoropheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4662 (4-Anilinoquinazoline 9 | N-(4-Chloro-2-fluoropheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4676 (4-Anilinoquinazoline 23 | N-(2-fluoro-4-methylphen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4663 (4-Anilinoquinazoline 10 | N-(4-Chloro-2-fluorophen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4638 (4-Anilinoquinazoline 8 | Anilinoquinazoline deriv....) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM21 (CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4677 (4-Anilinoquinazoline 24 | N-(4-chloro-2,6-difluoro...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4681 (4-Anilinoquinazoline 28 | N-(4-Bromo-2-fluoropheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4674 (4-Anilinoquinazoline 21 | N-(4-Chloro-2-fluorophen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4679 (4-Anilinoquinazoline 26 | N-(4-chloro-2-fluorophen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM4675 (4-Anilinoquinazoline 22 | N-(4-Bromo-2-fluoropheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4657 (4-Anilinoquinazoline 4 | N-(4-Chloro-2-fluoropheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4663 (4-Anilinoquinazoline 10 | N-(4-Chloro-2-fluorophen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human)) | BDBM4645 (4-Anilinoquinazoline 13 | Anilinoquinazoline deriv...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4628 (Anilinoquinazoline deriv. 11 | CHEMBL286160 | KDR ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4658 (4-Anilinoquinazoline 5 | N-(4-bromo-2-fluorophenyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4639 (4-Anilinoquinazoline 7 | Anilinoquinazoline deriv....) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4662 (4-Anilinoquinazoline 9 | N-(4-Chloro-2-fluoropheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4664 (4-Anilinoquinazoline 11 | N-(4-Bromo-2-fluoropheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4670 (2-chloro-4-fluoro-5-({6-methoxy-7-[(1-methylpiperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4682 (4-Anilinoquinazoline 29 | N-(4-chloro-2-fluorophen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4684 (4-Anilinoquinazoline 31 | N-(4-bromo-2-fluoropheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human)) | BDBM4680 (4-Anilinoquinazoline 27 | N-(4-Bromo-2-fluoropheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human)) | BDBM4681 (4-Anilinoquinazoline 28 | N-(4-Bromo-2-fluoropheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human)) | BDBM4662 (4-Anilinoquinazoline 9 | N-(4-Chloro-2-fluoropheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4680 (4-Anilinoquinazoline 27 | N-(4-Bromo-2-fluoropheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human)) | BDBM4639 (4-Anilinoquinazoline 7 | Anilinoquinazoline deriv....) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4681 (4-Anilinoquinazoline 28 | N-(4-Bromo-2-fluoropheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4683 (4-Anilinoquinazoline 30 | N-(4-bromo-2-fluoropheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM4659 (4-Anilinoquinazoline 6 | N-(4-Chloro-2-fluoropheny...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ... | J Med Chem 45: 1300-12 (2002) Article DOI: 10.1021/jm011022e BindingDB Entry DOI: 10.7270/Q29C6VMW | |||||||||||
More data for this Ligand-Target Pair |
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