Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466343 ((8S)-N-[(2S)-2- cyclopentyl-2- hydroxy-ethyl]-5- (...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466343 ((8S)-N-[(2S)-2- cyclopentyl-2- hydroxy-ethyl]-5- (...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM466343 ((8S)-N-[(2S)-2- cyclopentyl-2- hydroxy-ethyl]-5- (...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM466343 ((8S)-N-[(2S)-2- cyclopentyl-2- hydroxy-ethyl]-5- (...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466344 ((8S)-N-(2- cyclohexyl-2- hydroxy-ethyl)-5- (7H-pyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466344 ((8S)-N-(2- cyclohexyl-2- hydroxy-ethyl)-5- (7H-pyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM466344 ((8S)-N-(2- cyclohexyl-2- hydroxy-ethyl)-5- (7H-pyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM466344 ((8S)-N-(2- cyclohexyl-2- hydroxy-ethyl)-5- (7H-pyr...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466345 ((8S)-N-[(1S,2S)-2- cyclohexyl-2- hydroxy-1- methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466345 ((8S)-N-[(1S,2S)-2- cyclohexyl-2- hydroxy-1- methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM466345 ((8S)-N-[(1S,2S)-2- cyclohexyl-2- hydroxy-1- methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM466345 ((8S)-N-[(1S,2S)-2- cyclohexyl-2- hydroxy-1- methyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466346 ((8S)-N-[(2S)-2- cyclohexyl-2- hydroxy-ethyl]-5- (7...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466346 ((8S)-N-[(2S)-2- cyclohexyl-2- hydroxy-ethyl]-5- (7...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM466346 ((8S)-N-[(2S)-2- cyclohexyl-2- hydroxy-ethyl]-5- (7...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM466346 ((8S)-N-[(2S)-2- cyclohexyl-2- hydroxy-ethyl]-5- (7...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466347 ((8S)—N-[(1S,2S)-2-Cyclopentyl-2-Hydroxy-1-Methyl-E...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466347 ((8S)—N-[(1S,2S)-2-Cyclopentyl-2-Hydroxy-1-Methyl-E...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM466347 ((8S)—N-[(1S,2S)-2-Cyclopentyl-2-Hydroxy-1-Methyl-E...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM466347 ((8S)—N-[(1S,2S)-2-Cyclopentyl-2-Hydroxy-1-Methyl-E...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466348 ((8S)-N-[(1S,2S)-2- (4-fluorophenyl)- 2-hydroxy-1- ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466348 ((8S)-N-[(1S,2S)-2- (4-fluorophenyl)- 2-hydroxy-1- ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM466348 ((8S)-N-[(1S,2S)-2- (4-fluorophenyl)- 2-hydroxy-1- ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM466348 ((8S)-N-[(1S,2S)-2- (4-fluorophenyl)- 2-hydroxy-1- ...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466349 ((8S)-N-[(2S)-2-(4- fluorophenyl)-2- hydroxy-ethyl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466349 ((8S)-N-[(2S)-2-(4- fluorophenyl)-2- hydroxy-ethyl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM466349 ((8S)-N-[(2S)-2-(4- fluorophenyl)-2- hydroxy-ethyl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM466349 ((8S)-N-[(2S)-2-(4- fluorophenyl)-2- hydroxy-ethyl]...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466350 ((8S)-N-[(2S)-2-(4- cyanophenyl)-2- hydroxy-ethyl]-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466350 ((8S)-N-[(2S)-2-(4- cyanophenyl)-2- hydroxy-ethyl]-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM466350 ((8S)-N-[(2S)-2-(4- cyanophenyl)-2- hydroxy-ethyl]-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM466350 ((8S)-N-[(2S)-2-(4- cyanophenyl)-2- hydroxy-ethyl]-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 17.7 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466351 ((8S)-N-[(1S,2S)-2- (4-fluorophenyl)- 2-hydroxy-1- ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466351 ((8S)-N-[(1S,2S)-2- (4-fluorophenyl)- 2-hydroxy-1- ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM466351 ((8S)-N-[(1S,2S)-2- (4-fluorophenyl)- 2-hydroxy-1- ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM466351 ((8S)-N-[(1S,2S)-2- (4-fluorophenyl)- 2-hydroxy-1- ...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466352 ((8S)-N-[(2R)-2- hydroxy-2- tetrahydropyran- 4-yl-e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466352 ((8S)-N-[(2R)-2- hydroxy-2- tetrahydropyran- 4-yl-e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM466352 ((8S)-N-[(2R)-2- hydroxy-2- tetrahydropyran- 4-yl-e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 11.7 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM466352 ((8S)-N-[(2R)-2- hydroxy-2- tetrahydropyran- 4-yl-e...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 10.8 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466353 ((8S)-N-[(2R)-2- cyclopentyl-2- hydroxy-ethyl]-5- (...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466353 ((8S)-N-[(2R)-2- cyclopentyl-2- hydroxy-ethyl]-5- (...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM466353 ((8S)-N-[(2R)-2- cyclopentyl-2- hydroxy-ethyl]-5- (...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM466353 ((8S)-N-[(2R)-2- cyclopentyl-2- hydroxy-ethyl]-5- (...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 18.2 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466354 ((8S)-N-[(2R)-2-(5- fluoro-2-pyridyl)- 2-hydroxy-et...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466354 ((8S)-N-[(2R)-2-(5- fluoro-2-pyridyl)- 2-hydroxy-et...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM466354 ((8S)-N-[(2R)-2-(5- fluoro-2-pyridyl)- 2-hydroxy-et...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 26.5 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM466354 ((8S)-N-[(2R)-2-(5- fluoro-2-pyridyl)- 2-hydroxy-et...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 13.9 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM466355 ((8S)-N-[(4- cyanophenyl) methyl]-5-(7H- pyrrolo[2,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466355 ((8S)-N-[(4- cyanophenyl) methyl]-5-(7H- pyrrolo[2,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair |
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