Compile Data Set for Download or QSAR

Found 81 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 1369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM318840 ((R)-6-4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethy...) Show SMILES CNC1=C(C(=N)C2CC2)C(=O)N([C@@H]1c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 |r,c:2| Show InChI InChI=1S/C23H23ClN6O/c1-12-10-17(11-29-13(2)27-28-22(12)29)30-21(15-6-8-16(24)9-7-15)20(26-3)18(23(30)31)19(25)14-4-5-14/h6-11,14,21,25-26H,4-5H2,1-3H3/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318855 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(fluorom...) Show SMILES Cc1cc(cn2c(CF)nnc12)N1[C@@H](c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H20ClFN6O/c1-12-9-16(11-30-17(10-25)26-27-22(12)30)31-20(14-5-7-15(24)8-6-14)21-18(23(31)32)19(13-3-4-13)28-29(21)2/h5-9,11,13,20H,3-4,10H2,1-2H3/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM318855 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(fluorom...) Show SMILES Cc1cc(cn2c(CF)nnc12)N1[C@@H](c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H20ClFN6O/c1-12-9-16(11-30-17(10-25)26-27-22(12)30)31-20(14-5-7-15(24)8-6-14)21-18(23(31)32)19(13-3-4-13)28-29(21)2/h5-9,11,13,20H,3-4,10H2,1-2H3/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318855 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(fluorom...) Show SMILES Cc1cc(cn2c(CF)nnc12)N1[C@@H](c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H20ClFN6O/c1-12-9-16(11-30-17(10-25)26-27-22(12)30)31-20(14-5-7-15(24)8-6-14)21-18(23(31)32)19(13-3-4-13)28-29(21)2/h5-9,11,13,20H,3-4,10H2,1-2H3/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318861 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimeth...) Show SMILES Cc1nnc2c(C)cc(nn12)N1[C@@H](c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H20ClN7O/c1-11-10-16(26-30-12(2)24-25-21(11)30)29-19(14-6-8-15(23)9-7-14)20-17(22(29)31)18(13-4-5-13)27-28(20)3/h6-10,13,19H,4-5H2,1-3H3/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM318861 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimeth...) Show SMILES Cc1nnc2c(C)cc(nn12)N1[C@@H](c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H20ClN7O/c1-11-10-16(26-30-12(2)24-25-21(11)30)29-19(14-6-8-15(23)9-7-14)20-17(22(29)31)18(13-4-5-13)27-28(20)3/h6-10,13,19H,4-5H2,1-3H3/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318840 ((R)-6-4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethy...) Show SMILES CNC1=C(C(=N)C2CC2)C(=O)N([C@@H]1c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 |r,c:2| Show InChI InChI=1S/C23H23ClN6O/c1-12-10-17(11-29-13(2)27-28-22(12)29)30-21(15-6-8-16(24)9-7-15)20(26-3)18(23(30)31)19(25)14-4-5-14/h6-11,14,21,25-26H,4-5H2,1-3H3/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318845 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(difluor...) Show SMILES Cc1cc(cn2c(nnc12)C(F)F)N1[C@@H](c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H19ClF2N6O/c1-11-9-15(10-31-21(11)27-28-22(31)20(25)26)32-18(13-5-7-14(24)8-6-13)19-16(23(32)33)17(12-3-4-12)29-30(19)2/h5-10,12,18,20H,3-4H2,1-2H3/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318861 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimeth...) Show SMILES Cc1nnc2c(C)cc(nn12)N1[C@@H](c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H20ClN7O/c1-11-10-16(26-30-12(2)24-25-21(11)30)29-19(14-6-8-15(23)9-7-14)20-17(22(29)31)18(13-4-5-13)27-28(20)3/h6-10,13,19H,4-5H2,1-3H3/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318842 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(difluoromet...) Show SMILES COCCn1nc(C2CC2)c2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 Show InChI InChI=1S/C25H25ClN6O2/c1-14-12-19(13-30-15(2)27-28-24(14)30)32-22(17-6-8-18(26)9-7-17)23-20(25(32)33)21(16-4-5-16)29-31(23)10-11-34-3/h6-9,12-13,16,22H,4-5,10-11H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318842 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(difluoromet...) Show SMILES COCCn1nc(C2CC2)c2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 Show InChI InChI=1S/C25H25ClN6O2/c1-14-12-19(13-30-15(2)27-28-24(14)30)32-22(17-6-8-18(26)9-7-17)23-20(25(32)33)21(16-4-5-16)29-31(23)10-11-34-3/h6-9,12-13,16,22H,4-5,10-11H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318841 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(difluoromet...) Show SMILES Cc1cc(cn2c(nnc12)C(F)F)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H19ClF2N6O/c1-11-9-15(10-31-21(11)27-28-22(31)20(25)26)32-18(13-5-7-14(24)8-6-13)19-16(23(32)33)17(12-3-4-12)29-30(19)2/h5-10,12,18,20H,3-4H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318841 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(difluoromet...) Show SMILES Cc1cc(cn2c(nnc12)C(F)F)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H19ClF2N6O/c1-11-9-15(10-31-21(11)27-28-22(31)20(25)26)32-18(13-5-7-14(24)8-6-13)19-16(23(32)33)17(12-3-4-12)29-30(19)2/h5-10,12,18,20H,3-4H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318840 ((R)-6-4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethy...) Show SMILES CNC1=C(C(=N)C2CC2)C(=O)N([C@@H]1c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 |r,c:2| Show InChI InChI=1S/C23H23ClN6O/c1-12-10-17(11-29-13(2)27-28-22(12)29)30-21(15-6-8-16(24)9-7-15)20(26-3)18(23(30)31)19(25)14-4-5-14/h6-11,14,21,25-26H,4-5H2,1-3H3/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318845 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(difluor...) Show SMILES Cc1cc(cn2c(nnc12)C(F)F)N1[C@@H](c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H19ClF2N6O/c1-11-9-15(10-31-21(11)27-28-22(31)20(25)26)32-18(13-5-7-14(24)8-6-13)19-16(23(32)33)17(12-3-4-12)29-30(19)2/h5-10,12,18,20H,3-4H2,1-2H3/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318858 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimeth...) Show SMILES Cc1nnc2c(C)cc(cn12)N1[C@@H](c2c(C1=O)c(nn2C[C@H](O)C(F)(F)F)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H22ClF3N6O2/c1-12-9-17(10-33-13(2)30-31-23(12)33)35-21(15-5-7-16(26)8-6-15)22-19(24(35)37)20(14-3-4-14)32-34(22)11-18(36)25(27,28)29/h5-10,14,18,21,36H,3-4,11H2,1-2H3/t18-,21+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM318841 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(difluoromet...) Show SMILES Cc1cc(cn2c(nnc12)C(F)F)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H19ClF2N6O/c1-11-9-15(10-31-21(11)27-28-22(31)20(25)26)32-18(13-5-7-14(24)8-6-13)19-16(23(32)33)17(12-3-4-12)29-30(19)2/h5-10,12,18,20H,3-4H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318854 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(fluoromethy...) Show SMILES Cc1cc(cn2c(CF)nnc12)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H20ClFN6O/c1-12-9-16(11-30-17(10-25)26-27-22(12)30)31-20(14-5-7-15(24)8-6-14)21-18(23(31)32)19(13-3-4-13)28-29(21)2/h5-9,11,13,20H,3-4,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM318858 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimeth...) Show SMILES Cc1nnc2c(C)cc(cn12)N1[C@@H](c2c(C1=O)c(nn2C[C@H](O)C(F)(F)F)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H22ClF3N6O2/c1-12-9-17(10-33-13(2)30-31-23(12)33)35-21(15-5-7-16(26)8-6-15)22-19(24(35)37)20(14-3-4-14)32-34(22)11-18(36)25(27,28)29/h5-10,14,18,21,36H,3-4,11H2,1-2H3/t18-,21+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM318845 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(difluor...) Show SMILES Cc1cc(cn2c(nnc12)C(F)F)N1[C@@H](c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H19ClF2N6O/c1-11-9-15(10-31-21(11)27-28-22(31)20(25)26)32-18(13-5-7-14(24)8-6-13)19-16(23(32)33)17(12-3-4-12)29-30(19)2/h5-10,12,18,20H,3-4H2,1-2H3/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318847 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(1,4-dimeth...) Show SMILES Cc1cc(cc2n(C)nnc12)N1[C@@H](c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H21ClN6O/c1-12-10-16(11-17-19(12)25-27-28(17)2)30-21(14-6-8-15(24)9-7-14)22-18(23(30)31)20(13-4-5-13)26-29(22)3/h6-11,13,21H,4-5H2,1-3H3/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318847 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(1,4-dimeth...) Show SMILES Cc1cc(cc2n(C)nnc12)N1[C@@H](c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H21ClN6O/c1-12-10-16(11-17-19(12)25-27-28(17)2)30-21(14-6-8-15(24)9-7-14)22-18(23(30)31)20(13-4-5-13)26-29(22)3/h6-11,13,21H,4-5H2,1-3H3/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318858 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimeth...) Show SMILES Cc1nnc2c(C)cc(cn12)N1[C@@H](c2c(C1=O)c(nn2C[C@H](O)C(F)(F)F)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H22ClF3N6O2/c1-12-9-17(10-33-13(2)30-31-23(12)33)35-21(15-5-7-16(26)8-6-15)22-19(24(35)37)20(14-3-4-14)32-34(22)11-18(36)25(27,28)29/h5-10,14,18,21,36H,3-4,11H2,1-2H3/t18-,21+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318854 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(fluoromethy...) Show SMILES Cc1cc(cn2c(CF)nnc12)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H20ClFN6O/c1-12-9-16(11-30-17(10-25)26-27-22(12)30)31-20(14-5-7-15(24)8-6-14)21-18(23(31)32)19(13-3-4-13)28-29(21)2/h5-9,11,13,20H,3-4,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318853 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimeth...) Show SMILES COCCn1nc(C2CC2)c2C(=O)N([C@@H](c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 |r| Show InChI InChI=1S/C25H25ClN6O2/c1-14-12-19(13-30-15(2)27-28-24(14)30)32-22(17-6-8-18(26)9-7-17)23-20(25(32)33)21(16-4-5-16)29-31(23)10-11-34-3/h6-9,12-13,16,22H,4-5,10-11H2,1-3H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM318854 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(fluoromethy...) Show SMILES Cc1cc(cn2c(CF)nnc12)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H20ClFN6O/c1-12-9-16(11-30-17(10-25)26-27-22(12)30)31-20(14-5-7-15(24)8-6-14)21-18(23(31)32)19(13-3-4-13)28-29(21)2/h5-9,11,13,20H,3-4,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM318842 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(difluoromet...) Show SMILES COCCn1nc(C2CC2)c2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 Show InChI InChI=1S/C25H25ClN6O2/c1-14-12-19(13-30-15(2)27-28-24(14)30)32-22(17-6-8-18(26)9-7-17)23-20(25(32)33)21(16-4-5-16)29-31(23)10-11-34-3/h6-9,12-13,16,22H,4-5,10-11H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318859 (6-(4-chlorophenyl)-3-cyclopropyl-5-(1,4-dimethyl-1...) Show SMILES Cc1cc(cc2n(C)nnc12)N1C(c2c(C1=O)c(nn2-c1ccnn1C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H23ClN8O/c1-14-12-18(13-19-22(14)29-31-32(19)2)34-24(16-6-8-17(27)9-7-16)25-21(26(34)36)23(15-4-5-15)30-35(25)20-10-11-28-33(20)3/h6-13,15,24H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318846 (6-(4-chlorophenyl)-3-cyclopropyl-5-(1,4-dimethyl-1...) Show SMILES Cc1cc(cc2n(C)nnc12)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClN6O/c1-12-10-16(11-17-19(12)25-27-28(17)2)30-21(14-6-8-15(24)9-7-14)22-18(23(30)31)20(13-4-5-13)26-29(22)3/h6-11,13,21H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318853 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimeth...) Show SMILES COCCn1nc(C2CC2)c2C(=O)N([C@@H](c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 |r| Show InChI InChI=1S/C25H25ClN6O2/c1-14-12-19(13-30-15(2)27-28-24(14)30)32-22(17-6-8-18(26)9-7-17)23-20(25(32)33)21(16-4-5-16)29-31(23)10-11-34-3/h6-9,12-13,16,22H,4-5,10-11H2,1-3H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318846 (6-(4-chlorophenyl)-3-cyclopropyl-5-(1,4-dimethyl-1...) Show SMILES Cc1cc(cc2n(C)nnc12)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClN6O/c1-12-10-16(11-17-19(12)25-27-28(17)2)30-21(14-6-8-15(24)9-7-14)22-18(23(30)31)20(13-4-5-13)26-29(22)3/h6-11,13,21H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM318853 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimeth...) Show SMILES COCCn1nc(C2CC2)c2C(=O)N([C@@H](c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 |r| Show InChI InChI=1S/C25H25ClN6O2/c1-14-12-19(13-30-15(2)27-28-24(14)30)32-22(17-6-8-18(26)9-7-17)23-20(25(32)33)21(16-4-5-16)29-31(23)10-11-34-3/h6-9,12-13,16,22H,4-5,10-11H2,1-3H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM318847 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(1,4-dimeth...) Show SMILES Cc1cc(cc2n(C)nnc12)N1[C@@H](c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H21ClN6O/c1-12-10-16(11-17-19(12)25-27-28(17)2)30-21(14-6-8-15(24)9-7-14)22-18(23(30)31)20(13-4-5-13)26-29(22)3/h6-11,13,21H,4-5H2,1-3H3/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318864 (5-(8-amino-3-methyl-[1,2,4]triazolo[4,3-a]pyridin-...) Show SMILES Cc1nnc2c(N)cc(cn12)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H20ClN7O/c1-11-25-26-21-16(24)9-15(10-29(11)21)30-19(13-5-7-14(23)8-6-13)20-17(22(30)31)18(12-3-4-12)27-28(20)2/h5-10,12,19H,3-4,24H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318851 ((R)-6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]tria...) Show SMILES COc1ncccc1-c1nn(C)c2[C@H](N(C(=O)c12)c1cc(C)c2nnc(C)n2c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C26H22ClN7O2/c1-14-12-18(13-33-15(2)29-30-24(14)33)34-22(16-7-9-17(27)10-8-16)23-20(26(34)35)21(31-32(23)3)19-6-5-11-28-25(19)36-4/h5-13,22H,1-4H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318865 (US9624247, Example 29 | ethyl (6-(6-(4-chloropheny...) Show SMILES CCOC(=O)Nc1cc(cn2c(C)nnc12)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H24ClN7O3/c1-4-36-25(35)27-18-11-17(12-32-13(2)28-29-23(18)32)33-21(15-7-9-16(26)10-8-15)22-19(24(33)34)20(14-5-6-14)30-31(22)3/h7-12,14,21H,4-6H2,1-3H3,(H,27,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318844 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(difluoromet...) Show SMILES COc1cc(cc2n(C)nnc12)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClN6O2/c1-28-16-10-15(11-17(32-3)20(16)25-27-28)30-21(13-6-8-14(24)9-7-13)22-18(23(30)31)19(12-4-5-12)26-29(22)2/h6-12,21H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318859 (6-(4-chlorophenyl)-3-cyclopropyl-5-(1,4-dimethyl-1...) Show SMILES Cc1cc(cc2n(C)nnc12)N1C(c2c(C1=O)c(nn2-c1ccnn1C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H23ClN8O/c1-14-12-18(13-19-22(14)29-31-32(19)2)34-24(16-6-8-17(27)9-7-16)25-21(26(34)36)23(15-4-5-15)30-35(25)20-10-11-28-33(20)3/h6-13,15,24H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318865 (US9624247, Example 29 | ethyl (6-(6-(4-chloropheny...) Show SMILES CCOC(=O)Nc1cc(cn2c(C)nnc12)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H24ClN7O3/c1-4-36-25(35)27-18-11-17(12-32-13(2)28-29-23(18)32)33-21(15-7-9-16(26)10-8-15)22-19(24(33)34)20(14-5-6-14)30-31(22)3/h7-12,14,21H,4-6H2,1-3H3,(H,27,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM318865 (US9624247, Example 29 | ethyl (6-(6-(4-chloropheny...) Show SMILES CCOC(=O)Nc1cc(cn2c(C)nnc12)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H24ClN7O3/c1-4-36-25(35)27-18-11-17(12-32-13(2)28-29-23(18)32)33-21(15-7-9-16(26)10-8-15)22-19(24(33)34)20(14-5-6-14)30-31(22)3/h7-12,14,21H,4-6H2,1-3H3,(H,27,35)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318857 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimeth...) Show SMILES Cc1nnc2c(C)cc(cn12)N1[C@@H](c2c(C1=O)c(nn2C[C@@H](O)C(F)(F)F)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H22ClF3N6O2/c1-12-9-17(10-33-13(2)30-31-23(12)33)35-21(15-5-7-16(26)8-6-15)22-19(24(35)37)20(14-3-4-14)32-34(22)11-18(36)25(27,28)29/h5-10,14,18,21,36H,3-4,11H2,1-2H3/t18-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318839 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethyl-[...) Show SMILES CNC1=C(C(=N)C2CC2)C(=O)N(C1c1ccc(Cl)cc1)c1cc(C)c2nnc(C)n2c1 |c:2| Show InChI InChI=1S/C23H23ClN6O/c1-12-10-17(11-29-13(2)27-28-22(12)29)30-21(15-6-8-16(24)9-7-15)20(26-3)18(23(30)31)19(25)14-4-5-14/h6-11,14,21,25-26H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318851 ((R)-6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]tria...) Show SMILES COc1ncccc1-c1nn(C)c2[C@H](N(C(=O)c12)c1cc(C)c2nnc(C)n2c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C26H22ClN7O2/c1-14-12-18(13-33-15(2)29-30-24(14)33)34-22(16-7-9-17(27)10-8-16)23-20(26(34)35)21(31-32(23)3)19-6-5-11-28-25(19)36-4/h5-13,22H,1-4H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318856 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(fluoromethy...) Show SMILES COCCn1nc(C2CC2)c2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(CF)n2c1 Show InChI InChI=1S/C25H24ClFN6O2/c1-14-11-18(13-31-19(12-27)28-29-24(14)31)33-22(16-5-7-17(26)8-6-16)23-20(25(33)34)21(15-3-4-15)30-32(23)9-10-35-2/h5-8,11,13,15,22H,3-4,9-10,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318862 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethyl-[...) Show SMILES Cc1nnc2c(C)cc(nn12)N1C(c2c(C1=O)c(nn2-c1ccnn1C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H22ClN9O/c1-13-12-18(30-34-14(2)28-29-24(13)34)33-22(16-6-8-17(26)9-7-16)23-20(25(33)36)21(15-4-5-15)31-35(23)19-10-11-27-32(19)3/h6-12,15,22H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318856 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(fluoromethy...) Show SMILES COCCn1nc(C2CC2)c2C(=O)N(C(c12)c1ccc(Cl)cc1)c1cc(C)c2nnc(CF)n2c1 Show InChI InChI=1S/C25H24ClFN6O2/c1-14-11-18(13-31-19(12-27)28-29-24(14)31)33-22(16-5-7-17(26)8-6-16)23-20(25(33)34)21(15-3-4-15)30-32(23)9-10-35-2/h5-8,11,13,15,22H,3-4,9-10,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM318862 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimethyl-[...) Show SMILES Cc1nnc2c(C)cc(nn12)N1C(c2c(C1=O)c(nn2-c1ccnn1C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H22ClN9O/c1-13-12-18(30-34-14(2)28-29-24(13)34)33-22(16-6-8-17(26)9-7-16)23-20(25(33)36)21(15-4-5-15)31-35(23)19-10-11-27-32(19)3/h6-12,15,22H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318844 (6-(4-chlorophenyl)-3-cyclopropyl-5-(3-(difluoromet...) Show SMILES COc1cc(cc2n(C)nnc12)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClN6O2/c1-28-16-10-15(11-17(32-3)20(16)25-27-28)30-21(13-6-8-14(24)9-7-13)22-18(23(30)31)19(12-4-5-12)26-29(22)2/h6-12,21H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM318857 ((R)-6-(4-chlorophenyl)-3-cyclopropyl-5-(3,8-dimeth...) Show SMILES Cc1nnc2c(C)cc(cn12)N1[C@@H](c2c(C1=O)c(nn2C[C@@H](O)C(F)(F)F)C1CC1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H22ClF3N6O2/c1-12-9-17(10-33-13(2)30-31-23(12)33)35-21(15-5-7-16(26)8-6-15)22-19(24(35)37)20(14-3-4-14)32-34(22)11-18(36)25(27,28)29/h5-10,14,18,21,36H,3-4,11H2,1-2H3/t18-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM318846 (6-(4-chlorophenyl)-3-cyclopropyl-5-(1,4-dimethyl-1...) Show SMILES Cc1cc(cc2n(C)nnc12)N1C(c2c(C1=O)c(nn2C)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H21ClN6O/c1-12-10-16(11-17-19(12)25-27-28(17)2)30-21(14-6-8-15(24)9-7-14)22-18(23(30)31)20(13-4-5-13)26-29(22)3/h6-11,13,21H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...				US Patent US9624247 (2017) BindingDB Entry DOI: 10.7270/Q28S4S02
					More data for this Ligand-Target Pair

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