Compile Data Set for Download or QSAR

Found 30 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 1699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13528 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1Cn1cccn1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H22F3N5O2/c20-14-10-16(22)15(21)8-12(14)7-13(23)9-18(28)27-6-1-3-24-19(29)17(27)11-26-5-2-4-25-26/h2,4-5,8,10,13,17H,1,3,6-7,9,11,23H2,(H,24,29)/t13-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.290	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13527 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1Cc1ccccn1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H23F3N4O2/c22-16-12-18(24)17(23)9-13(16)8-14(25)10-20(29)28-7-3-6-27-21(30)19(28)11-15-4-1-2-5-26-15/h1-2,4-5,9,12,14,19H,3,6-8,10-11,25H2,(H,27,30)/t14-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.490	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13526 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1Cc1ccccc1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C22H24F3N3O2/c23-17-13-19(25)18(24)11-15(17)10-16(26)12-21(29)28-8-4-7-27-22(30)20(28)9-14-5-2-1-3-6-14/h1-3,5-6,11,13,16,20H,4,7-10,12,26H2,(H,27,30)/t16-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.910	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13525 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1CC(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C17H19F6N3O2/c18-11-7-13(20)12(19)5-9(11)4-10(24)6-15(27)26-3-1-2-25-16(28)14(26)8-17(21,22)23/h5,7,10,14H,1-4,6,8,24H2,(H,25,28)/t10-,14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13519 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES C[C@H]1N(CCCNC1=O)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C16H20F3N3O2/c1-9-16(24)21-3-2-4-22(9)15(23)7-11(20)5-10-6-13(18)14(19)8-12(10)17/h6,8-9,11H,2-5,7,20H2,1H3,(H,21,24)/t9-,11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13515 ((3R)-3-amino-4-(2,5-difluorophenyl)-1-[(8R)-8-meth...) Show SMILES C[C@H]1N(CCn2c1nnc2C(F)(F)F)C(=O)C[C@H](N)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C17H18F5N5O/c1-9-15-24-25-16(17(20,21)22)27(15)5-4-26(9)14(28)8-12(23)7-10-6-11(18)2-3-13(10)19/h2-3,6,9,12H,4-5,7-8,23H2,1H3/t9-,12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13518 ((3R)-4-[(3R)-3-amino-4-(2,5-difluorophenyl)butanoy...) Show SMILES C[C@H]1N(CCCNC1=O)C(=O)C[C@H](N)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C16H21F2N3O2/c1-10-16(23)20-5-2-6-21(10)15(22)9-13(19)8-11-7-12(17)3-4-14(11)18/h3-4,7,10,13H,2,5-6,8-9,19H2,1H3,(H,20,23)/t10-,13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13524 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES CC[C@H]1N(CCCNC1=O)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C17H22F3N3O2/c1-2-15-17(25)22-4-3-5-23(15)16(24)8-11(21)6-10-7-13(19)14(20)9-12(10)18/h7,9,11,15H,2-6,8,21H2,1H3,(H,22,25)/t11-,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11162 ((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11160 ((3R)-3-amino-4-(2,5-difluorophenyl)-1-[3-(trifluor...) Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C16H16F5N5O/c17-10-1-2-12(18)9(5-10)6-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,5,11H,3-4,6-8,22H2/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13517 ((3R)-4-[(3R)-3-amino-4-(2,5-difluorophenyl)butanoy...) Show SMILES C[C@H]1N(CCNC1=O)C(=O)C[C@H](N)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C15H19F2N3O2/c1-9-15(22)19-4-5-20(9)14(21)8-12(18)7-10-6-11(16)2-3-13(10)17/h2-3,6,9,12H,4-5,7-8,18H2,1H3,(H,19,22)/t9-,12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13523 (1,4-diazepan-2-one 2c | 4-[(3R)-3-amino-4-(2,4,5-t...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)C1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C15H18F3N3O2/c16-11-7-13(18)12(17)5-9(11)4-10(19)6-15(23)21-3-1-2-20-14(22)8-21/h5,7,10H,1-4,6,8,19H2,(H,20,22)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13520 ((3S)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES C[C@@H]1N(CCCNC1=O)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C16H20F3N3O2/c1-9-16(24)21-3-2-4-22(9)15(23)7-11(20)5-10-6-13(18)14(19)8-12(10)17/h6,8-9,11H,2-5,7,20H2,1H3,(H,21,24)/t9-,11+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13516 ((5R)-1-[(3R)-3-amino-4-(2,5-difluorophenyl)butanoy...) Show SMILES C[C@H]1N(CNC1=O)C(=O)C[C@H](N)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C14H17F2N3O2/c1-8-14(21)18-7-19(8)13(20)6-11(17)5-9-4-10(15)2-3-12(9)16/h2-4,8,11H,5-7,17H2,1H3,(H,18,21)/t8-,11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13521 ((3S)-4-[(3S)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES C[C@@H]1N(CCCNC1=O)C(=O)C[C@@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C16H20F3N3O2/c1-9-16(24)21-3-2-4-22(9)15(23)7-11(20)5-10-6-13(18)14(19)8-12(10)17/h6,8-9,11H,2-5,7,20H2,1H3,(H,21,24)/t9-,11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM13524 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES CC[C@H]1N(CCCNC1=O)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C17H22F3N3O2/c1-2-15-17(25)22-4-3-5-23(15)16(24)8-11(21)6-10-7-13(19)14(20)9-12(10)18/h7,9,11,15H,2-6,8,21H2,1H3,(H,22,25)/t11-,15-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM13526 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1Cc1ccccc1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C22H24F3N3O2/c23-17-13-19(25)18(24)11-15(17)10-16(26)12-21(29)28-8-4-7-27-22(30)20(28)9-14-5-2-1-3-6-14/h1-3,5-6,11,13,16,20H,4,7-10,12,26H2,(H,27,30)/t16-,20-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM13526 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1Cc1ccccc1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C22H24F3N3O2/c23-17-13-19(25)18(24)11-15(17)10-16(26)12-21(29)28-8-4-7-27-22(30)20(28)9-14-5-2-1-3-6-14/h1-3,5-6,11,13,16,20H,4,7-10,12,26H2,(H,27,30)/t16-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM13525 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1CC(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C17H19F6N3O2/c18-11-7-13(20)12(19)5-9(11)4-10(24)6-15(27)26-3-1-2-25-16(28)14(26)8-17(21,22)23/h5,7,10,14H,1-4,6,8,24H2,(H,25,28)/t10-,14-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM13519 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES C[C@H]1N(CCCNC1=O)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C16H20F3N3O2/c1-9-16(24)21-3-2-4-22(9)15(23)7-11(20)5-10-6-13(18)14(19)8-12(10)17/h6,8-9,11H,2-5,7,20H2,1H3,(H,21,24)/t9-,11-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM13524 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES CC[C@H]1N(CCCNC1=O)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C17H22F3N3O2/c1-2-15-17(25)22-4-3-5-23(15)16(24)8-11(21)6-10-7-13(19)14(20)9-12(10)18/h7,9,11,15H,2-6,8,21H2,1H3,(H,22,25)/t11-,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM13527 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1Cc1ccccn1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H23F3N4O2/c22-16-12-18(24)17(23)9-13(16)8-14(25)10-20(29)28-7-3-6-27-21(30)19(28)11-15-4-1-2-5-26-15/h1-2,4-5,9,12,14,19H,3,6-8,10-11,25H2,(H,27,30)/t14-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM13525 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1CC(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C17H19F6N3O2/c18-11-7-13(20)12(19)5-9(11)4-10(24)6-15(27)26-3-1-2-25-16(28)14(26)8-17(21,22)23/h5,7,10,14H,1-4,6,8,24H2,(H,25,28)/t10-,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	DrugBank PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM13519 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES C[C@H]1N(CCCNC1=O)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C16H20F3N3O2/c1-9-16(24)21-3-2-4-22(9)15(23)7-11(20)5-10-6-13(18)14(19)8-12(10)17/h6,8-9,11H,2-5,7,20H2,1H3,(H,21,24)/t9-,11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM13522 ((3R)-4-[(3S)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES C[C@H]1N(CCCNC1=O)C(=O)C[C@@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C16H20F3N3O2/c1-9-16(24)21-3-2-4-22(9)15(23)7-11(20)5-10-6-13(18)14(19)8-12(10)17/h6,8-9,11H,2-5,7,20H2,1H3,(H,21,24)/t9-,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	7.5	37
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM13528 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1Cn1cccn1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H22F3N5O2/c20-14-10-16(22)15(21)8-12(14)7-13(23)9-18(28)27-6-1-3-24-19(29)17(27)11-26-5-2-4-25-26/h2,4-5,8,10,13,17H,1,3,6-7,9,11,23H2,(H,24,29)/t13-,17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM13528 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1Cn1cccn1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H22F3N5O2/c20-14-10-16(22)15(21)8-12(14)7-13(23)9-18(28)27-6-1-3-24-19(29)17(27)11-26-5-2-4-25-26/h2,4-5,8,10,13,17H,1,3,6-7,9,11,23H2,(H,24,29)/t13-,17-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM13523 (1,4-diazepan-2-one 2c | 4-[(3R)-3-amino-4-(2,4,5-t...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)C1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C15H18F3N3O2/c16-11-7-13(18)12(17)5-9(11)4-10(19)6-15(23)21-3-1-2-20-14(22)8-21/h5,7,10H,1-4,6,8,19H2,(H,20,22)/t10-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM13527 ((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1Cc1ccccn1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H23F3N4O2/c22-16-12-18(24)17(23)9-13(16)8-14(25)10-20(29)28-7-3-6-27-21(30)19(28)11-15-4-1-2-5-26-15/h1-2,4-5,9,12,14,19H,3,6-8,10-11,25H2,(H,27,30)/t14-,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM13523 (1,4-diazepan-2-one 2c | 4-[(3R)-3-amino-4-(2,4,5-t...) Show SMILES N[C@@H](CC(=O)N1CCCNC(=O)C1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C15H18F3N3O2/c16-11-7-13(18)12(17)5-9(11)4-10(19)6-15(23)21-3-1-2-20-14(22)8-21/h5,7,10H,1-4,6,8,19H2,(H,20,22)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...				Bioorg Med Chem Lett 17: 49-52 (2007) Article DOI: 10.1016/j.bmcl.2006.09.099 BindingDB Entry DOI: 10.7270/Q2F47MC2
					More data for this Ligand-Target Pair