Compile Data Set for Download or QSAR

Found 49 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 2436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365351 (6-amino-N-[bis(3- hydroxypropyl)(oxido)-lambda4- s...) Show SMILES Cc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)C(=O)N=S(=O)(CCCO)CCCO)c1 Show InChI InChI=1S/C28H31N5O5S2/c1-18-5-2-6-21(13-18)31-28(37)32-22-7-8-24-19(14-22)16-25(39-24)23-15-20(17-30-26(23)29)27(36)33-40(38,11-3-9-34)12-4-10-35/h2,5-8,13-17,34-35H,3-4,9-12H2,1H3,(H2,29,30)(H2,31,32,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364999 (US10633373, Example 16 | US10669265, Example 16 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(F)cc3F)ccc2s1 Show InChI InChI=1S/C22H16F2N4O3S/c1-31-21(29)12-7-15(20(25)26-10-12)19-8-11-6-14(3-5-18(11)32-19)27-22(30)28-17-4-2-13(23)9-16(17)24/h2-10H,1H3,(H2,25,26)(H2,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364997 (US10633373, Example 14 | US10669265, Example 14 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccccc3F)ccc2s1 Show InChI InChI=1S/C22H17FN4O3S/c1-30-21(28)13-9-15(20(24)25-11-13)19-10-12-8-14(6-7-18(12)31-19)26-22(29)27-17-5-3-2-4-16(17)23/h2-11H,1H3,(H2,24,25)(H2,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365217 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)B2OC(C)(C)C(C)(C)O2)c1 Show InChI InChI=1S/C27H28BFN4O3S/c1-15-6-8-20(29)21(10-15)33-25(34)32-18-7-9-22-16(11-18)12-23(37-22)19-13-17(14-31-24(19)30)28-35-26(2,3)27(4,5)36-28/h6-14H,1-5H3,(H2,30,31)(H2,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364986 (US10633373, Example 7 | US10669265, Example 7 | US...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cccc(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C23H17F3N4O3S/c1-33-21(31)13-8-17(20(27)28-11-13)19-9-12-7-16(5-6-18(12)34-19)30-22(32)29-15-4-2-3-14(10-15)23(24,25)26/h2-11H,1H3,(H2,27,28)(H2,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364996 (US10633373, Example 13 | US10669265, Example 13 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(C)cc3)ccc2s1 Show InChI InChI=1S/C23H20N4O3S/c1-13-3-5-16(6-4-13)26-23(29)27-17-7-8-19-14(9-17)11-20(31-19)18-10-15(22(28)30-2)12-25-21(18)24/h3-12H,1-2H3,(H2,24,25)(H2,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365367 (US10633373, Example 72 | US10669265, Example 72 | ...) Show SMILES COC(=O)CCCCS(=O)(CCCCC(=O)OC)=NC(=O)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C32H36F3N5O7S/c1-46-27(41)10-3-5-16-48(45,17-6-4-11-28(42)47-2)40-30(43)22-18-26(29(36)37-20-22)21-12-14-24(15-13-21)38-31(44)39-25-9-7-8-23(19-25)32(33,34)35/h7-9,12-15,18-20H,3-6,10-11,16-17H2,1-2H3,(H2,36,37)(H2,38,39,44)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364992 (US10633373, Example 10 | US10669265, Example 10 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(C)ccc3F)ccc2s1 Show InChI InChI=1S/C23H19FN4O3S/c1-12-3-5-17(24)18(7-12)28-23(30)27-15-4-6-19-13(8-15)10-20(32-19)16-9-14(22(29)31-2)11-26-21(16)25/h3-11H,1-2H3,(H2,25,26)(H2,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365348 (US10633373, Example 53 | US10669265, Example 53 | ...) Show SMILES COC(=O)CCCC[S@](C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cccc(C)c3)ccc2s1 |r| Show InChI InChI=1S/C29H31N5O5S2/c1-18-7-6-8-21(13-18)32-29(37)33-22-10-11-24-19(14-22)16-25(40-24)23-15-20(17-31-27(23)30)28(36)34-41(3,38)12-5-4-9-26(35)39-2/h6-8,10-11,13-17H,4-5,9,12H2,1-3H3,(H2,30,31)(H2,32,33,37)/t41-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM363243 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)C(=O)N=S(C)(C)=O)c1 Show InChI InChI=1S/C24H22FN5O3S2/c1-13-4-6-18(25)19(8-13)29-24(32)28-16-5-7-20-14(9-16)11-21(34-20)17-10-15(12-27-22(17)26)23(31)30-35(2,3)33/h4-12H,1-3H3,(H2,26,27)(H2,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM363234 (6-amino-5-[5-({[(3-chloro-4- fluorophenyl)amino]ca...) Show SMILES CS(C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(F)c(Cl)c3)ccc2s1 Show InChI InChI=1S/C23H19ClFN5O3S2/c1-35(2,33)30-22(31)13-8-16(21(26)27-11-13)20-9-12-7-14(4-6-19(12)34-20)28-23(32)29-15-3-5-18(25)17(24)10-15/h3-11H,1-2H3,(H2,26,27)(H2,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365013 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES CC1(C)OB(OC1(C)C)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(ccc3F)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C27H25BF4N4O3S/c1-25(2)26(3,4)39-28(38-25)16-12-18(23(33)34-13-16)22-10-14-9-17(6-8-21(14)40-22)35-24(37)36-20-11-15(27(30,31)32)5-7-19(20)29/h5-13H,1-4H3,(H2,33,34)(H2,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364994 (US10633373, Example 11 | US10669265, Example 11 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cccc(C)c3)ccc2s1 Show InChI InChI=1S/C23H20N4O3S/c1-13-4-3-5-16(8-13)26-23(29)27-17-6-7-19-14(9-17)11-20(31-19)18-10-15(22(28)30-2)12-25-21(18)24/h3-12H,1-2H3,(H2,24,25)(H2,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365308 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES CCc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)B2OC(C)(C)C(C)(C)O2)c1 Show InChI InChI=1S/C28H31BN4O3S/c1-6-17-8-7-9-20(12-17)32-26(34)33-21-10-11-23-18(13-21)14-24(37-23)22-15-19(16-31-25(22)30)29-35-27(2,3)28(4,5)36-29/h7-16H,6H2,1-5H3,(H2,30,31)(H2,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365309 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES Cc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)B2OC(C)(C)C(C)(C)O2)c1 Show InChI InChI=1S/C27H29BN4O3S/c1-16-7-6-8-19(11-16)31-25(33)32-20-9-10-22-17(12-20)13-23(36-22)21-14-18(15-30-24(21)29)28-34-26(2,3)27(4,5)35-28/h6-15H,1-5H3,(H2,29,30)(H2,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM363197 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES Cc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)C(=O)N=S(C)(C)=O)c1 Show InChI InChI=1S/C24H23N5O3S2/c1-14-5-4-6-17(9-14)27-24(31)28-18-7-8-20-15(10-18)12-21(33-20)19-11-16(13-26-22(19)25)23(30)29-34(2,3)32/h4-13H,1-3H3,(H2,25,26)(H2,27,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364980 (6-amino-5-{5-[({[4-chloro-3- (trifluoromethyl)phen...) Show SMILES CS(C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C24H19ClF3N5O3S2/c1-38(2,36)33-22(34)13-8-16(21(29)30-11-13)20-9-12-7-14(4-6-19(12)37-20)31-23(35)32-15-3-5-18(25)17(10-15)24(26,27)28/h3-11H,1-2H3,(H2,29,30)(H2,31,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365216 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES CC1(C)OB(OC1(C)C)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C27H25BClF3N4O3S/c1-25(2)26(3,4)39-28(38-25)15-11-18(23(33)34-13-15)22-10-14-9-16(6-8-21(14)40-22)35-24(37)36-17-5-7-20(29)19(12-17)27(30,31)32/h5-13H,1-4H3,(H2,33,34)(H2,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364990 (US10633373, Example 8 | US10669265, Example 8 | US...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(ccc3F)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C23H16F4N4O3S/c1-34-21(32)12-7-15(20(28)29-10-12)19-8-11-6-14(3-5-18(11)35-19)30-22(33)31-17-9-13(23(25,26)27)2-4-16(17)24/h2-10H,1H3,(H2,28,29)(H2,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365357 (1-{4-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cc(cnc2N)B2OC(C)(C)C(C)(C)O2)c1 Show InChI InChI=1S/C25H28BFN4O3/c1-15-6-11-20(27)21(12-15)31-23(32)30-18-9-7-16(8-10-18)19-13-17(14-29-22(19)28)26-33-24(2,3)25(4,5)34-26/h6-14H,1-5H3,(H2,28,29)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365338 (US10633373, Example 43 | US10669265, Example 43 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)c3ccc(F)c(Cl)c3)ccc2s1 Show InChI InChI=1S/C22H15ClFN3O3S/c1-30-22(29)13-7-15(20(25)26-10-13)19-9-12-6-14(3-5-18(12)31-19)27-21(28)11-2-4-17(24)16(23)8-11/h2-10H,1H3,(H2,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365335 (US10633373, Example 40 | US10669265, Example 40 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)c3cccc(C)c3)ccc2s1 Show InChI InChI=1S/C23H19N3O3S/c1-13-4-3-5-14(8-13)22(27)26-17-6-7-19-15(9-17)11-20(30-19)18-10-16(23(28)29-2)12-25-21(18)24/h3-12H,1-2H3,(H2,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364995 (US10633373, Example 12 | US10669265, Example 12 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(F)c(Cl)c3)ccc2s1 Show InChI InChI=1S/C22H16ClFN4O3S/c1-31-21(29)12-7-15(20(25)26-10-12)19-8-11-6-13(3-5-18(11)32-19)27-22(30)28-14-2-4-17(24)16(23)9-14/h2-10H,1H3,(H2,25,26)(H2,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364984 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES CS(C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cc(ccc3F)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C24H19F4N5O3S2/c1-38(2,36)33-22(34)13-8-16(21(29)30-11-13)20-9-12-7-15(4-6-19(12)37-20)31-23(35)32-18-10-14(24(26,27)28)3-5-17(18)25/h3-11H,1-2H3,(H2,29,30)(H2,31,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364998 (US10633373, Example 15 | US10669265, Example 15 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccccc3)ccc2s1 Show InChI InChI=1S/C22H18N4O3S/c1-29-21(27)14-10-17(20(23)24-12-14)19-11-13-9-16(7-8-18(13)30-19)26-22(28)25-15-5-3-2-4-6-15/h2-12H,1H3,(H2,23,24)(H2,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365339 (US10633373, Example 44 | US10669265, Example 44 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)c3cc(ccc3F)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C23H15F4N3O3S/c1-33-22(32)12-7-16(20(28)29-10-12)19-8-11-6-14(3-5-18(11)34-19)30-21(31)15-9-13(23(25,26)27)2-4-17(15)24/h2-10H,1H3,(H2,28,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365315 (6-amino-5-(5-{[4-chloro-3- (trifluoromethyl)benzoy...) Show SMILES CS(C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)c3ccc(Cl)c(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C24H18ClF3N4O3S2/c1-37(2,35)32-23(34)14-8-16(21(29)30-11-14)20-10-13-7-15(4-6-19(13)36-20)31-22(33)12-3-5-18(25)17(9-12)24(26,27)28/h3-11H,1-2H3,(H2,29,30)(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365336 (US10633373, Example 41 | US10669265, Example 41 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)c3cc(C)ccc3F)ccc2s1 Show InChI InChI=1S/C23H18FN3O3S/c1-12-3-5-18(24)16(7-12)22(28)27-15-4-6-19-13(8-15)10-20(31-19)17-9-14(23(29)30-2)11-26-21(17)25/h3-11H,1-2H3,(H2,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365312 (US10633373, Example 31 | US10669265, Example 31 | ...) Show SMILES Cc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)B(O)O)c1 Show InChI InChI=1S/C21H19BN4O3S/c1-12-3-2-4-15(7-12)25-21(27)26-16-5-6-18-13(8-16)9-19(30-18)17-10-14(22(28)29)11-24-20(17)23/h2-11,28-29H,1H3,(H2,23,24)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364991 (US10633373, Example 9 | US10669265, Example 9 | US...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C23H16ClF3N4O3S/c1-34-21(32)12-7-15(20(28)29-10-12)19-8-11-6-13(3-5-18(11)35-19)30-22(33)31-14-2-4-17(24)16(9-14)23(25,26)27/h2-10H,1H3,(H2,28,29)(H2,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365356 (US10633373, Example 61 | US10669265, Example 61 | ...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cc(cnc2N)B(O)O)c1 Show InChI InChI=1S/C19H18BFN4O3/c1-11-2-7-16(21)17(8-11)25-19(26)24-14-5-3-12(4-6-14)15-9-13(20(27)28)10-23-18(15)22/h2-10,27-28H,1H3,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365326 (US10633373, Example 39 | US10669265, Example 39 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)c3occc3C)ccc2s1 Show InChI InChI=1S/C21H17N3O4S/c1-11-5-6-28-18(11)20(25)24-14-3-4-16-12(7-14)9-17(29-16)15-8-13(21(26)27-2)10-23-19(15)22/h3-10H,1-2H3,(H2,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM364977 (6-amino-5-{5- [(anilinocarbonyl)amino]-1- benzothi...) Show SMILES CS(C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccccc3)ccc2s1 Show InChI InChI=1S/C23H21N5O3S2/c1-33(2,31)28-22(29)15-11-18(21(24)25-13-15)20-12-14-10-17(8-9-19(14)32-20)27-23(30)26-16-6-4-3-5-7-16/h3-13H,1-2H3,(H2,24,25)(H2,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365360 (US10633373, Example 65 | US10669265, Example 65 | ...) Show SMILES CCOP(=O)(OCC)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1 Show InChI InChI=1S/C23H26FN4O4P/c1-4-31-33(30,32-5-2)18-13-19(22(25)26-14-18)16-7-9-17(10-8-16)27-23(29)28-21-12-15(3)6-11-20(21)24/h6-14H,4-5H2,1-3H3,(H2,25,26)(H2,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365364 (6-amino-N-[bis(3- hydroxypropyl)(oxido)-lambda6- s...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cc(cnc2N)C(=O)N=S(=O)(CCCO)CCCO)c1 Show InChI InChI=1S/C26H31N5O5S/c1-18-5-2-6-22(15-18)30-26(35)29-21-9-7-19(8-10-21)23-16-20(17-28-24(23)27)25(34)31-37(36,13-3-11-32)14-4-12-33/h2,5-10,15-17,32-33H,3-4,11-14H2,1H3,(H2,27,28)(H2,29,30,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365366 (US10633373, Example 71 | US10669265, Example 71 | ...) Show SMILES COC(=O)CCCCS(=O)(CCCCC(=O)OC)=NC(=O)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1 Show InChI InChI=1S/C32H38FN5O7S/c1-21-10-15-26(33)27(18-21)37-32(42)36-24-13-11-22(12-14-24)25-19-23(20-35-30(25)34)31(41)38-46(43,16-6-4-8-28(39)44-2)17-7-5-9-29(40)45-3/h10-15,18-20H,4-9,16-17H2,1-3H3,(H2,34,35)(H2,36,37,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365354 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cc(cnc2N)C(=O)N=S(=O)(CCCO)CCCO)c1 Show InChI InChI=1S/C26H30FN5O5S/c1-17-4-9-22(27)23(14-17)31-26(36)30-20-7-5-18(6-8-20)21-15-19(16-29-24(21)28)25(35)32-38(37,12-2-10-33)13-3-11-34/h4-9,14-16,33-34H,2-3,10-13H2,1H3,(H2,28,29)(H2,30,31,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365322 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES CS(C)(=O)=NC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)c3cc(ccc3F)C(F)(F)F)ccc2s1 Show InChI InChI=1S/C24H18F4N4O3S2/c1-37(2,35)32-22(33)13-8-17(21(29)30-11-13)20-9-12-7-15(4-6-19(12)36-20)31-23(34)16-10-14(24(26,27)28)3-5-18(16)25/h3-11H,1-2H3,(H2,29,30)(H,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365311 (1-{2-[2-amino-5-(4,4,5,5- tetramethyl-1,3,2- dioxa...) Show SMILES CC1(C)OB(OC1(C)C)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3ccccc3)ccc2s1 Show InChI InChI=1S/C26H27BN4O3S/c1-25(2)26(3,4)34-27(33-25)17-14-20(23(28)29-15-17)22-13-16-12-19(10-11-21(16)35-22)31-24(32)30-18-8-6-5-7-9-18/h5-15H,1-4H3,(H2,28,29)(H2,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365321 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES Cc1cccc(c1)C(=O)Nc1ccc2sc(cc2c1)-c1cc(cnc1N)C(=O)N=S(C)(C)=O Show InChI InChI=1S/C24H22N4O3S2/c1-14-5-4-6-15(9-14)23(29)27-18-7-8-20-16(10-18)12-21(32-20)19-11-17(13-26-22(19)25)24(30)28-33(2,3)31/h4-13H,1-3H3,(H2,25,26)(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365365 (US10633373, Example 70 | US10669265, Example 70 | ...) Show SMILES COC(=O)CCCCS(=O)(CCCCC(=O)OC)=NC(=O)c1cnc(N)c(c1)-c1ccc(NC(=O)Nc2cccc(C)c2)cc1 Show InChI InChI=1S/C32H39N5O7S/c1-22-9-8-10-26(19-22)36-32(41)35-25-15-13-23(14-16-25)27-20-24(21-34-30(27)33)31(40)37-45(42,17-6-4-11-28(38)43-2)18-7-5-12-29(39)44-3/h8-10,13-16,19-21H,4-7,11-12,17-18H2,1-3H3,(H2,33,34)(H2,35,36,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365313 ((6-amino-5-{5- [(anilinocarbonyl)amino]-1- benzoth...) Show SMILES Nc1ncc(cc1-c1cc2cc(NC(=O)Nc3ccccc3)ccc2s1)B(O)O Show InChI InChI=1S/C20H17BN4O3S/c22-19-16(10-13(11-23-19)21(27)28)18-9-12-8-15(6-7-17(12)29-18)25-20(26)24-14-4-2-1-3-5-14/h1-11,27-28H,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365318 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES Cc1ccc(F)c(c1)C(=O)Nc1ccc2sc(cc2c1)-c1cc(cnc1N)C(=O)N=S(C)(C)=O Show InChI InChI=1S/C24H21FN4O3S2/c1-13-4-6-19(25)17(8-13)24(31)28-16-5-7-20-14(9-16)11-21(33-20)18-10-15(12-27-22(18)26)23(30)29-34(2,3)32/h4-12H,1-3H3,(H2,26,27)(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	258	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365005 (6-amino-5-[5-({[(3- methylphenyl)amino]carbonyl} a...) Show SMILES Cc1cccc(NC(=O)Nc2ccc3sc(cc3c2)-c2cc(cnc2N)C(O)=O)c1 Show InChI InChI=1S/C22H18N4O3S/c1-12-3-2-4-15(7-12)25-22(29)26-16-5-6-18-13(8-16)10-19(30-18)17-9-14(21(27)28)11-24-20(17)23/h2-11H,1H3,(H2,23,24)(H,27,28)(H2,25,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	431	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365314 (6-amino-N-[dimethyl(oxido)- lambda4-sulfanylidene]...) Show SMILES Cc1ccoc1C(=O)Nc1ccc2sc(cc2c1)-c1cc(cnc1N)C(=O)N=S(C)(C)=O Show InChI InChI=1S/C22H20N4O4S2/c1-12-6-7-30-19(12)22(28)25-15-4-5-17-13(8-15)10-18(31-17)16-9-14(11-24-20(16)23)21(27)26-32(2,3)29/h4-11H,1-3H3,(H2,23,24)(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	457	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365337 (6-amino-5-[5-[5 (benzoylamino)-1-benzothien- 2-yl]...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)c3ccccc3)ccc2s1 Show InChI InChI=1S/C22H17N3O3S/c1-28-22(27)15-10-17(20(23)24-12-15)19-11-14-9-16(7-8-18(14)29-19)25-21(26)13-5-3-2-4-6-13/h2-12H,1H3,(H2,23,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	503	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365340 (US10633373, Example 45 | US10669265, Example 45 | ...) Show SMILES COC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)c3cc4ccccc4o3)ccc2s1 Show InChI InChI=1S/C24H17N3O4S/c1-30-24(29)15-9-17(22(25)26-12-15)21-11-14-8-16(6-7-20(14)32-21)27-23(28)19-10-13-4-2-3-5-18(13)31-19/h2-12H,1H3,(H2,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	936	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365343 (N-[2-(2-aminopyridin-3-yl)-1- benzothien-5-yl]-3- ...) Show SMILES Cc1cccc(c1)C(=O)Nc1ccc2sc(cc2c1)-c1cccnc1N Show InChI InChI=1S/C21H17N3OS/c1-13-4-2-5-14(10-13)21(25)24-16-7-8-18-15(11-16)12-19(26-18)17-6-3-9-23-20(17)22/h2-12H,1H3,(H2,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM365347 (2-(2-aminopyridin-3-yl)-N-(3- methylphenyl)-1- ben...) Show SMILES Cc1cccc(NC(=O)c2ccc3sc(cc3c2)-c2cccnc2N)c1 Show InChI InChI=1S/C21H17N3OS/c1-13-4-2-5-16(10-13)24-21(25)14-7-8-18-15(11-14)12-19(26-18)17-6-3-9-23-20(17)22/h2-12H,1H3,(H2,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2DB8465
					More data for this Ligand-Target Pair