Compile Data Set for Download or QSAR

Found 23 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 8454   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM249390 (US9464081, 22) Show SMILES [#6]-[#6@@H](-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccccc12)-[#6](\F)=[#6](\[#6])-[#6] |r| Show InChI InChI=1S/C22H26FN5O3/c1-11(2)19(23)12(3)25-22(31)17-9-13-8-16(13)28(17)18(29)10-27-15-7-5-4-6-14(15)20(26-27)21(24)30/h4-7,12-13,16-17H,8-10H2,1-3H3,(H2,24,30)(H,25,31)/t12-,13-,16-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249386 (US9464081, 19) Show SMILES [#6]-[#6](-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccccc12)-[#6](\F)=[#6](\[#6])-[#6] |r| Show InChI InChI=1S/C22H26FN5O3/c1-11(2)19(23)12(3)25-22(31)17-9-13-8-16(13)28(17)18(29)10-27-15-7-5-4-6-14(15)20(26-27)21(24)30/h4-7,12-13,16-17H,8-10H2,1-3H3,(H2,24,30)(H,25,31)/t12?,13-,16-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249383 (US9464081, 16) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#6])=O)c2cc(-[#8]-[#6]-c3ncccn3)ccc12 |r| Show InChI InChI=1S/C27H29FN6O4/c1-15(2)20(28)12-31-27(37)23-10-17-9-22(17)34(23)25(36)13-33-21-6-5-18(11-19(21)26(32-33)16(3)35)38-14-24-29-7-4-8-30-24/h4-8,11,17,22-23H,9-10,12-14H2,1-3H3,(H,31,37)/t17-,22-,23+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249378 (US9464081, 11) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#6])=O)c2ccccc12 |r| Show InChI InChI=1S/C22H25FN4O3/c1-12(2)16(23)10-24-22(30)19-9-14-8-18(14)27(19)20(29)11-26-17-7-5-4-6-15(17)21(25-26)13(3)28/h4-7,14,18-19H,8-11H2,1-3H3,(H,24,30)/t14-,18-,19+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249389 (US9464081, 23) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#7]-c1cn(-[#6](-[#7])=O)c2ccccc12 |r| Show InChI InChI=1S/C21H24FN5O3/c1-11(2)14(22)9-24-19(28)18-8-12-7-17(12)27(18)21(30)25-15-10-26(20(23)29)16-6-4-3-5-13(15)16/h3-6,10,12,17-18H,7-9H2,1-2H3,(H2,23,29)(H,24,28)(H,25,30)/t12-,17-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249368 (US9464081, 1) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccc(Cl)cc12 Show InChI InChI=1S/C21H23ClFN5O3/c1-10(2)14(23)8-25-21(31)17-6-11-5-15(11)28(17)18(29)9-27-16-7-12(22)3-4-13(16)19(26-27)20(24)30/h3-4,7,11,15,17H,5-6,8-9H2,1-2H3,(H2,24,30)(H,25,31)/t11-,15-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249369 (US9464081, 2) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccccc12 |r| Show InChI InChI=1S/C21H24FN5O3/c1-11(2)14(22)9-24-21(30)17-8-12-7-16(12)27(17)18(28)10-26-15-6-4-3-5-13(15)19(25-26)20(23)29/h3-6,12,16-17H,7-10H2,1-2H3,(H2,23,29)(H,24,30)/t12-,16-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249380 (US9464081, 13) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#6])=O)c2ccncc12 |r| Show InChI InChI=1S/C21H24FN5O3/c1-11(2)15(22)8-24-21(30)17-7-13-6-16(13)27(17)19(29)10-26-18-9-23-5-4-14(18)20(25-26)12(3)28/h4-5,9,13,16-17H,6-8,10H2,1-3H3,(H,24,30)/t13-,16-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249382 (US9464081, 15) Show SMILES [#6]-[#6]-c1cc2c(nn(-[#6]-[#6](=O)-[#7]-3-[#6@@H]-4-[#6]-[#6@@H]-4-[#6]-[#6@H]-3-[#6](=O)-[#7]-[#6]\[#6](F)=[#6](\[#6])-[#6])c2cn1)-[#6](-[#7])=O |r| Show InChI InChI=1S/C22H27FN6O3/c1-4-13-7-14-18(9-25-13)28(27-20(14)21(24)31)10-19(30)29-16-5-12(16)6-17(29)22(32)26-8-15(23)11(2)3/h7,9,12,16-17H,4-6,8,10H2,1-3H3,(H2,24,31)(H,26,32)/t12-,16-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249385 (US9464081, 18) Show SMILES [#6]\[#6](-[#6])=[#6](\F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccccc12 |r| Show InChI InChI=1S/C21H24FN5O3/c1-11(2)14(22)9-24-21(30)17-8-12-7-16(12)27(17)18(28)10-26-15-6-4-3-5-13(15)19(25-26)20(23)29/h3-6,12,16-17H,7-10H2,1-2H3,(H2,23,29)(H,24,30)/t12-,16-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249374 (US9464081, 7) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@@H](F)-[#6]-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccccc12 |r| Show InChI InChI=1S/C20H23F2N5O3/c1-11(2)14(22)8-24-20(30)16-7-12(21)9-26(16)17(28)10-27-15-6-4-3-5-13(15)18(25-27)19(23)29/h3-6,12,16H,7-10H2,1-2H3,(H2,23,29)(H,24,30)/t12-,16+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249375 (US9464081, 8) Show SMILES [#6]-[#8]-[#6@@H]-1-[#6@@H](F)-[#6]-[#7](-[#6@@H]-1-[#6](=O)-[#7]-[#6]\[#6](F)=[#6](\[#6])-[#6])-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccccc12 |r| Show InChI InChI=1S/C21H25F2N5O4/c1-11(2)13(22)8-25-21(31)18-19(32-3)14(23)9-27(18)16(29)10-28-15-7-5-4-6-12(15)17(26-28)20(24)30/h4-7,14,18-19H,8-10H2,1-3H3,(H2,24,30)(H,25,31)/t14-,18-,19+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	59	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249381 (US9464081, 14) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccnc(-[#6])c12 |r| Show InChI InChI=1S/C21H25FN6O3/c1-10(2)14(22)8-25-21(31)16-7-12-6-15(12)28(16)17(29)9-27-19-11(3)24-5-4-13(19)18(26-27)20(23)30/h4-5,12,15-16H,6-9H2,1-3H3,(H2,23,30)(H,25,31)/t12-,15-,16+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249379 (US9464081, 12) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2cc(-[#6])ncc12 |r| Show InChI InChI=1S/C21H25FN6O3/c1-10(2)14(22)7-25-21(31)16-6-12-5-15(12)28(16)18(29)9-27-17-8-24-11(3)4-13(17)19(26-27)20(23)30/h4,8,12,15-16H,5-7,9H2,1-3H3,(H2,23,30)(H,25,31)/t12-,15-,16+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	74	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249377 (US9464081, 10) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccncc12 |r| Show InChI InChI=1S/C20H23FN6O3/c1-10(2)13(21)7-24-20(30)15-6-11-5-14(11)27(15)17(28)9-26-16-8-23-4-3-12(16)18(25-26)19(22)29/h3-4,8,11,14-15H,5-7,9H2,1-2H3,(H2,22,29)(H,24,30)/t11-,14-,15+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	78	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249387 (US9464081, 20) Show SMILES NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC\C(F)=C\C(F)(F)F)c2ccccc12 |r| Show InChI InChI=1S/C20H19F4N5O3/c21-11(7-20(22,23)24)8-26-19(32)15-6-10-5-14(10)29(15)16(30)9-28-13-4-2-1-3-12(13)17(27-28)18(25)31/h1-4,7,10,14-15H,5-6,8-9H2,(H2,25,31)(H,26,32)/b11-7-/t10-,14-,15+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249373 (US9464081, 6) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6][C@@]2([#6]-[#8])[#6]-[#6@H]2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccccc12 |r| Show InChI InChI=1S/C22H26FN5O4/c1-12(2)14(23)9-25-21(32)16-7-22(11-29)8-17(22)28(16)18(30)10-27-15-6-4-3-5-13(15)19(26-27)20(24)31/h3-6,16-17,29H,7-11H2,1-2H3,(H2,24,31)(H,25,32)/t16-,17+,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	99	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249384 (US9464081, 17) Show SMILES [#7]-[#6](=O)-c1nn(-[#6]-[#6](=O)-[#7]-2-[#6@@H]-3-[#6]-[#6@@H]-3-[#6]-[#6@H]-2-[#6](=O)-[#7]-[#6]\[#6](F)=[#6]-2\[#6]-[#6]-[#6]-[#6]-2)c2ccccc12 |r| Show InChI InChI=1S/C23H26FN5O3/c24-16(13-5-1-2-6-13)11-26-23(32)19-10-14-9-18(14)29(19)20(30)12-28-17-8-4-3-7-15(17)21(27-28)22(25)31/h3-4,7-8,14,18-19H,1-2,5-6,9-12H2,(H2,25,31)(H,26,32)/t14-,18-,19+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	128	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249372 (US9464081, 5) Show SMILES [#6]-[#8]-[#6@@H]-1-[#6@@H](F)-[#6]-[#7](-[#6@@H]-1-[#6](=O)-[#7]-[#6]\[#6](F)=[#6](\[#6])-[#6])-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccncc12 |r| Show InChI InChI=1S/C20H24F2N6O4/c1-10(2)12(21)6-25-20(31)17-18(32-3)13(22)8-27(17)15(29)9-28-14-7-24-5-4-11(14)16(26-28)19(23)30/h4-5,7,13,17-18H,6,8-9H2,1-3H3,(H2,23,30)(H,25,31)/t13-,17-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	253	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249370 (US9464081, 3) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@@H](F)-[#6]-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccncc12 |r| Show InChI InChI=1S/C19H22F2N6O3/c1-10(2)13(21)6-24-19(30)14-5-11(20)8-26(14)16(28)9-27-15-7-23-4-3-12(15)17(25-27)18(22)29/h3-4,7,11,14H,5-6,8-9H2,1-2H3,(H2,22,29)(H,24,30)/t11-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	255	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249376 (US9464081, 9) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2cc(-[#6])nc(-[#6])c12 |r| Show InChI InChI=1S/C22H27FN6O3/c1-10(2)15(23)8-25-22(32)17-7-13-6-16(13)29(17)18(30)9-28-20-12(4)26-11(3)5-14(20)19(27-28)21(24)31/h5,13,16-17H,6-9H2,1-4H3,(H2,24,31)(H,25,32)/t13-,16-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	356	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249371 (US9464081, 4) Show SMILES [#6]\[#6](-[#6])=[#6](/F)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccc(-[#6])cc12 |r| Show InChI InChI=1S/C22H26FN5O3/c1-11(2)15(23)9-25-22(31)18-8-13-7-16(13)28(18)19(29)10-27-17-6-12(3)4-5-14(17)20(26-27)21(24)30/h4-6,13,16,18H,7-10H2,1-3H3,(H2,24,30)(H,25,31)/t13-,16-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	450	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM249388 (US9464081, 21) Show SMILES [#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@H]-2-[#6]-[#6@H]-2-[#7]-1-[#6](=O)-[#6]-n1nc(-[#6](-[#7])=O)c2ccccc12)-[#6](\F)=[#6](\[#6])-[#6] |r| Show InChI InChI=1S/C22H26FN5O3/c1-11(2)19(23)12(3)25-22(31)17-9-13-8-16(13)28(17)18(29)10-27-15-7-5-4-6-14(15)20(26-27)21(24)30/h4-7,12-13,16-17H,8-10H2,1-3H3,(H2,24,30)(H,25,31)/t12-,13+,16+,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...				US Patent US9464081 (2016) BindingDB Entry DOI: 10.7270/Q2PN94K2
					More data for this Ligand-Target Pair