Compile Data Set for Download or QSAR

Found 40 hits of ph data with Target = 'Cathepsin L'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin L (Capra hircus (Goat))	BDBM192658 (N’-(2-nitrophenylmethylene)benzohydrazide (1i...) Show SMILES [O-][N+](=O)c1ccccc1\C=N\NC(=O)c1ccccc1 Show InChI InChI=1S/C14H11N3O3/c18-14(11-6-2-1-3-7-11)16-15-10-12-8-4-5-9-13(12)17(19)20/h1-10H,(H,16,18)/b15-10+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	4.20	-49.7	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192660 (N’-(4-nitrophenylmethylene)benzohydrazide (1k...) Show SMILES [O-][N+](=O)c1ccc(\C=N\NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C14H11N3O3/c18-14(12-4-2-1-3-5-12)16-15-10-11-6-8-13(9-7-11)17(19)20/h1-10H,(H,16,18)/b15-10+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.53	-49.0	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192659 (N’-(3-nitrophenylmethylene)benzohydrazide (1j...) Show SMILES [O-][N+](=O)c1cccc(\C=N\NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C14H11N3O3/c18-14(12-6-2-1-3-7-12)16-15-10-11-5-4-8-13(9-11)17(19)20/h1-10H,(H,16,18)/b15-10+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.86	-48.9	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192654 (N’-(4-chlorophenylmethylene)benzohydrazide (1...) Show SMILES Clc1ccc(\C=N\NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C14H11ClN2O/c15-13-8-6-11(7-9-13)10-16-17-14(18)12-4-2-1-3-5-12/h1-10H,(H,17,18)/b16-10+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	6.34	-48.7	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192652 (N’-(2-chlorophenylmethylene)benzohydrazide (1...) Show SMILES Clc1ccccc1\C=N\NC(=O)c1ccccc1 Show InChI InChI=1S/C14H11ClN2O/c15-13-9-5-4-8-12(13)10-16-17-14(18)11-6-2-1-3-7-11/h1-10H,(H,17,18)/b16-10+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	7.30	-48.3	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192655 (N’-(2-methoxyphenylmethylene)benzohydrazide (...) Show SMILES COc1ccccc1\C=N\NC(=O)c1ccccc1 Show InChI InChI=1S/C15H14N2O2/c1-19-14-10-6-5-9-13(14)11-16-17-15(18)12-7-3-2-4-8-12/h2-11H,1H3,(H,17,18)/b16-11+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	8.14	-48.0	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192653 (N’-(3-chlorophenylmethylene)benzohydrazide (1...) Show SMILES Clc1cccc(\C=N\NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C14H11ClN2O/c15-13-8-4-5-11(9-13)10-16-17-14(18)12-6-2-1-3-7-12/h1-10H,(H,17,18)/b16-10+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	8.63	-47.9	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192650 (N’-(phenylmethylene)benzohydrazide (1a)) Show SMILES O=C(N\N=C\c1ccccc1)c1ccccc1 Show InChI InChI=1S/C14H12N2O/c17-14(13-9-5-2-6-10-13)16-15-11-12-7-3-1-4-8-12/h1-11H,(H,16,17)/b15-11+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	13	-46.8	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192657 (N’-(4-methoxyphenylmethylene)benzohydrazide (...) Show SMILES COc1ccc(\C=N\NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C15H14N2O2/c1-19-14-9-7-12(8-10-14)11-16-17-15(18)13-5-3-2-4-6-13/h2-11H,1H3,(H,17,18)/b16-11+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	19.8	-45.7	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192656 (N’-(3-methoxyphenylmethylene)benzohydrazide (...) Show SMILES COc1cccc(\C=N\NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C15H14N2O2/c1-19-14-9-5-6-12(10-14)11-16-17-15(18)13-7-3-2-4-8-13/h2-11H,1H3,(H,17,18)/b16-11+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	28.6	-44.8	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192668 (2-phenyl-5-(4-nitrophenyl)-1,3,4-oxadiazole (2k)) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1nnc(o1)-c1ccccc1 Show InChI InChI=1S/C14H9N3O3/c18-17(19)12-8-6-11(7-9-12)14-16-15-13(20-14)10-4-2-1-3-5-10/h1-9H	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	47.3	-43.5	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192667 (2-phenyl-5-(2-nitrophenyl)-1,3,4-oxadiazole (2i)) Show SMILES [O-][N+](=O)c1ccccc1-c1nnc(o1)-c1ccccc1 Show InChI InChI=1S/C14H9N3O3/c18-17(19)12-9-5-4-8-11(12)14-16-15-13(20-14)10-6-2-1-3-7-10/h1-9H	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	57	-43.0	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM63525 (2-(3-nitrophenyl)-5-phenyl-1,3,4-oxadiazole | 2-ph...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1nnc(o1)-c1ccccc1 Show InChI InChI=1S/C14H9N3O3/c18-17(19)12-8-4-7-11(9-12)14-16-15-13(20-14)10-5-2-1-3-6-10/h1-9H	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	63.4	-42.7	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM48184 (2-(3-chlorophenyl)-5-phenyl-1,3,4-oxadiazole | 2-p...) Show SMILES Clc1cccc(c1)-c1nnc(o1)-c1ccccc1 Show InChI InChI=1S/C14H9ClN2O/c15-12-8-4-7-11(9-12)14-17-16-13(18-14)10-5-2-1-3-6-10/h1-9H	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	70.2	-42.5	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192662 (2-phenyl-5-(2-chlorophenyl)-1,3,4-oxadiazole (2c)) Show SMILES Clc1ccccc1-c1nnc(o1)-c1ccccc1 Show InChI InChI=1S/C14H9ClN2O/c15-12-9-5-4-8-11(12)14-17-16-13(18-14)10-6-2-1-3-7-10/h1-9H	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	92.1	-41.8	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192651 (N’-(4-methylphenylmethylene)benzohydrazide (1...) Show SMILES Cc1ccc(\C=N\NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C15H14N2O/c1-12-7-9-13(10-8-12)11-16-17-15(18)14-5-3-2-4-6-14/h2-11H,1H3,(H,17,18)/b16-11+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	95.9	-41.7	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192663 (2-phenyl-5-(4-chlorophenyl)-1,3,4-oxadiazole (2e)) Show SMILES Clc1ccc(cc1)-c1nnc(o1)-c1ccccc1 Show InChI InChI=1S/C14H9ClN2O/c15-12-8-6-11(7-9-12)14-17-16-13(18-14)10-4-2-1-3-5-10/h1-9H	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	99.3	-41.6	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192661 (2,5-diphenyl-1,3,4-oxadiazole (2a)) Show SMILES c1ccc(cc1)-c1nnc(o1)-c1ccccc1 Show InChI InChI=1S/C14H10N2O/c1-3-7-11(8-4-1)13-15-16-14(17-13)12-9-5-2-6-10-12/h1-10H	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	124	-41.0	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192665 (2-phenyl-5-(3-methoxyphenyl)-1,3,4-oxadiazole (2g)) Show SMILES COc1cccc(c1)-c1nnc(o1)-c1ccccc1 Show InChI InChI=1S/C15H12N2O2/c1-18-13-9-5-8-12(10-13)15-17-16-14(19-15)11-6-3-2-4-7-11/h2-10H,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	144	-40.6	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192664 (2-phenyl-5-(2-methoxyphenyl)-1,3,4-oxadiazole (2f)) Show SMILES COc1ccccc1-c1nnc(o1)-c1ccccc1 Show InChI InChI=1S/C15H12N2O2/c1-18-13-10-6-5-9-12(13)15-17-16-14(19-15)11-7-3-2-4-8-11/h2-10H,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	216	-39.6	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM192666 (2-phenyl-5-(4-methoxyphenyl)-1,3,4-oxadiazole (2h)) Show SMILES COc1ccc(cc1)-c1nnc(o1)-c1ccccc1 Show InChI InChI=1S/C15H12N2O2/c1-18-13-9-7-12(8-10-13)15-17-16-14(19-15)11-5-3-2-4-6-11/h2-10H,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	337	-38.4	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Capra hircus (Goat))	BDBM49356 (2-(4-methylphenyl)-5-phenyl-1,3,4-oxadiazole | 2-P...) Show SMILES Cc1ccc(cc1)-c1nnc(o1)-c1ccccc1 Show InChI InChI=1S/C15H12N2O/c1-11-7-9-13(10-8-11)15-17-16-14(18-15)12-5-3-2-4-6-12/h2-10H,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	1.36E+3	-34.8	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93184 (Cathepsin Inhibitor, Column 6 Row 2) Show SMILES CC(NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cc2ccccc2s1)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C35H32N4O4S/c1-23(30(40)22-37-33(41)20-25-12-9-14-26(18-25)28-15-7-8-17-36-28)38-34(42)29(19-24-10-3-2-4-11-24)39-35(43)32-21-27-13-5-6-16-31(27)44-32/h2-18,21,23,29H,19-20,22H2,1H3,(H,37,41)(H,38,42)(H,39,43)/t23?,29-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93178 (Cathepsin Inhibitor, Column 4 Row 2) Show SMILES CC(NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc2ncccc2c1)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C36H33N5O4/c1-24(33(42)23-39-34(43)21-26-11-7-12-27(19-26)30-14-5-6-17-37-30)40-36(45)32(20-25-9-3-2-4-10-25)41-35(44)29-15-16-31-28(22-29)13-8-18-38-31/h2-19,22,24,32H,20-21,23H2,1H3,(H,39,43)(H,40,45)(H,41,44)/t24?,32-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93175 (Cathepsin Inhibitor, Column 3 Row 2) Show SMILES COc1ccc(cc1OC)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C35H36N4O6/c1-23(30(40)22-37-33(41)20-25-12-9-13-26(18-25)28-14-7-8-17-36-28)38-35(43)29(19-24-10-5-4-6-11-24)39-34(42)27-15-16-31(44-2)32(21-27)45-3/h4-18,21,23,29H,19-20,22H2,1-3H3,(H,37,41)(H,38,43)(H,39,42)/t23?,29-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93183 (Cathepsin Inhibitor, Column 6 Row 1) Show SMILES CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C32H34N4O4S/c1-20(2)15-26(36-32(40)29-18-24-10-4-5-13-28(24)41-29)31(39)35-21(3)27(37)19-34-30(38)17-22-9-8-11-23(16-22)25-12-6-7-14-33-25/h4-14,16,18,20-21,26H,15,17,19H2,1-3H3,(H,34,38)(H,35,39)(H,36,40)/t21?,26-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93181 (Cathepsin Inhibitor, Column 5 Row 2) Show SMILES CC(NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc2ccccc2n1)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C36H33N5O4/c1-24(33(42)23-38-34(43)22-26-12-9-14-28(20-26)29-15-7-8-19-37-29)39-36(45)32(21-25-10-3-2-4-11-25)41-35(44)31-18-17-27-13-5-6-16-30(27)40-31/h2-20,24,32H,21-23H2,1H3,(H,38,43)(H,39,45)(H,41,44)/t24?,32-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93172 (Cathepsin Inhibitor, Column 2 Row 2) Show SMILES CC(NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(F)(F)F)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C34H31F3N4O4/c1-22(30(42)21-39-31(43)20-24-10-7-11-26(18-24)28-12-5-6-17-38-28)40-33(45)29(19-23-8-3-2-4-9-23)41-32(44)25-13-15-27(16-14-25)34(35,36)37/h2-18,22,29H,19-21H2,1H3,(H,39,43)(H,40,45)(H,41,44)/t22?,29-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93180 (Cathepsin Inhibitor, Column 5 Row 1) Show SMILES CC(C)C[C@H](NC(=O)c1ccc2ccccc2n1)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C33H35N5O4/c1-21(2)17-29(38-32(41)28-15-14-24-10-4-5-13-27(24)37-28)33(42)36-22(3)30(39)20-35-31(40)19-23-9-8-11-25(18-23)26-12-6-7-16-34-26/h4-16,18,21-22,29H,17,19-20H2,1-3H3,(H,35,40)(H,36,42)(H,38,41)/t22?,29-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93177 (Cathepsin Inhibitor, Column 4 Row 1) Show SMILES CC(C)C[C@H](NC(=O)c1ccc2ncccc2c1)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C33H35N5O4/c1-21(2)16-29(38-32(41)26-12-13-28-25(19-26)10-7-15-35-28)33(42)37-22(3)30(39)20-36-31(40)18-23-8-6-9-24(17-23)27-11-4-5-14-34-27/h4-15,17,19,21-22,29H,16,18,20H2,1-3H3,(H,36,40)(H,37,42)(H,38,41)/t22?,29-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93174 (Cathepsin Inhibitor, Column 3 Row 1) Show SMILES COc1ccc(cc1OC)C(=O)N[C@@H](CC(C)C)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C32H38N4O6/c1-20(2)15-26(36-31(39)24-12-13-28(41-4)29(18-24)42-5)32(40)35-21(3)27(37)19-34-30(38)17-22-9-8-10-23(16-22)25-11-6-7-14-33-25/h6-14,16,18,20-21,26H,15,17,19H2,1-5H3,(H,34,38)(H,35,40)(H,36,39)/t21?,26-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93171 (Cathepsin Inhibitor, Column 2 Row 1) Show SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1)C(F)(F)F)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C31H33F3N4O4/c1-19(2)15-26(38-29(41)22-10-12-24(13-11-22)31(32,33)34)30(42)37-20(3)27(39)18-36-28(40)17-21-7-6-8-23(16-21)25-9-4-5-14-35-25/h4-14,16,19-20,26H,15,17-18H2,1-3H3,(H,36,40)(H,37,42)(H,38,41)/t20?,26-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93168 (Cathepsin Inhibitor, Column 1 Row 1) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C25H32N4O4/c1-16(2)12-22(29-18(4)30)25(33)28-17(3)23(31)15-27-24(32)14-19-8-7-9-20(13-19)21-10-5-6-11-26-21/h5-11,13,16-17,22H,12,14-15H2,1-4H3,(H,27,32)(H,28,33)(H,29,30)/t17?,22-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93169 (Cathepsin Inhibitor, Column 1 Row 2) Show SMILES CC(NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C28H30N4O4/c1-19(31-28(36)25(32-20(2)33)16-21-9-4-3-5-10-21)26(34)18-30-27(35)17-22-11-8-12-23(15-22)24-13-6-7-14-29-24/h3-15,19,25H,16-18H2,1-2H3,(H,30,35)(H,31,36)(H,32,33)/t19?,25-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93170 (Cathepsin Inhibitor, Column 1 Row 3) Show SMILES CC(C)[C@H](NC(C)=O)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C24H30N4O4/c1-15(2)23(28-17(4)29)24(32)27-16(3)21(30)14-26-22(31)13-18-8-7-9-19(12-18)20-10-5-6-11-25-20/h5-12,15-16,23H,13-14H2,1-4H3,(H,26,31)(H,27,32)(H,28,29)/t16?,23-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93173 (Cathepsin Inhibitor, Column 2 Row 3) Show SMILES CC(C)[C@H](NC(=O)c1ccc(cc1)C(F)(F)F)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C30H31F3N4O4/c1-18(2)27(37-28(40)21-10-12-23(13-11-21)30(31,32)33)29(41)36-19(3)25(38)17-35-26(39)16-20-7-6-8-22(15-20)24-9-4-5-14-34-24/h4-15,18-19,27H,16-17H2,1-3H3,(H,35,39)(H,36,41)(H,37,40)/t19?,27-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93176 (Cathepsin Inhibitor, Column 3 Row 3) Show SMILES COc1ccc(cc1OC)C(=O)N[C@@H](C(C)C)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C31H36N4O6/c1-19(2)29(35-30(38)23-12-13-26(40-4)27(17-23)41-5)31(39)34-20(3)25(36)18-33-28(37)16-21-9-8-10-22(15-21)24-11-6-7-14-32-24/h6-15,17,19-20,29H,16,18H2,1-5H3,(H,33,37)(H,34,39)(H,35,38)/t20?,29-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93179 (Cathepsin Inhibitor, Column 4 Row 3) Show SMILES CC(C)[C@H](NC(=O)c1ccc2ncccc2c1)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C32H33N5O4/c1-20(2)30(37-31(40)25-12-13-27-24(18-25)10-7-15-34-27)32(41)36-21(3)28(38)19-35-29(39)17-22-8-6-9-23(16-22)26-11-4-5-14-33-26/h4-16,18,20-21,30H,17,19H2,1-3H3,(H,35,39)(H,36,41)(H,37,40)/t21?,30-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93182 (Cathepsin Inhibitor, Column 5 Row 3) Show SMILES CC(C)[C@H](NC(=O)c1ccc2ccccc2n1)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C32H33N5O4/c1-20(2)30(37-31(40)27-15-14-23-10-4-5-13-26(23)36-27)32(41)35-21(3)28(38)19-34-29(39)18-22-9-8-11-24(17-22)25-12-6-7-16-33-25/h4-17,20-21,30H,18-19H2,1-3H3,(H,34,39)(H,35,41)(H,37,40)/t21?,30-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair
Cathepsin L (Homo sapiens (Human))	BDBM93185 (Cathepsin Inhibitor, Column 6 Row 3) Show SMILES CC(C)[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1 |r| Show InChI InChI=1S/C31H32N4O4S/c1-19(2)29(35-30(38)27-17-23-10-4-5-13-26(23)40-27)31(39)34-20(3)25(36)18-33-28(37)16-21-9-8-11-22(15-21)24-12-6-7-14-32-24/h4-15,17,19-20,29H,16,18H2,1-3H3,(H,33,37)(H,34,39)(H,35,38)/t20?,29-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	5.5	n/a
SmithKline Beecham Pharmaceuticals					Assay Description Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...				J Comb Chem 1: 207-15 (1999) Article DOI: 10.1021/cc9800374 BindingDB Entry DOI: 10.7270/Q2HQ3XHJ
					More data for this Ligand-Target Pair